WO2010042207A3 - Methods of making collagen fiber medical constructs and related medical constructs, including nerve guides and patches - Google Patents

Methods of making collagen fiber medical constructs and related medical constructs, including nerve guides and patches Download PDF

Info

Publication number
WO2010042207A3
WO2010042207A3 PCT/US2009/005542 US2009005542W WO2010042207A3 WO 2010042207 A3 WO2010042207 A3 WO 2010042207A3 US 2009005542 W US2009005542 W US 2009005542W WO 2010042207 A3 WO2010042207 A3 WO 2010042207A3
Authority
WO
WIPO (PCT)
Prior art keywords
medical constructs
collagen fiber
patches
methods
constructs
Prior art date
Application number
PCT/US2009/005542
Other languages
French (fr)
Other versions
WO2010042207A2 (en
Inventor
Mengyan Li
Thomas J. Koob
Original Assignee
Mimedx, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mimedx, Inc. filed Critical Mimedx, Inc.
Priority to CA2740009A priority Critical patent/CA2740009C/en
Priority to EP09819572.0A priority patent/EP2349364B1/en
Publication of WO2010042207A2 publication Critical patent/WO2010042207A2/en
Publication of WO2010042207A3 publication Critical patent/WO2010042207A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/11Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
    • A61B17/1128Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis of nerves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/11Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
    • A61B17/1146Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis of tendons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B50/00Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers
    • A61B50/30Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A61L15/325Collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24Collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/26Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58Materials at least partially resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/043Proteins; Polypeptides; Degradation products thereof
    • A61L31/044Collagen
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B37/00Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding
    • B32B37/14Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding characterised by the properties of the layers
    • B32B37/142Laminating of sheets, panels or inserts, e.g. stiffeners, by wrapping in at least one outer layer, or inserting into a preformed pocket
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B37/00Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding
    • B32B37/14Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding characterised by the properties of the layers
    • B32B37/16Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding characterised by the properties of the layers with all layers existing as coherent layers before laminating
    • B32B37/20Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding characterised by the properties of the layers with all layers existing as coherent layers before laminating involving the assembly of continuous webs only
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B38/00Ancillary operations in connection with laminating processes
    • B32B38/08Impregnating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00491Surgical glue applicators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0401Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06166Sutures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00526Methods of manufacturing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B2017/06052Needle-suture combinations in which a suture is extending inside a hollow tubular needle, e.g. over the entire length of the needle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06066Needles, e.g. needle tip configurations
    • A61B2017/06071Needles, e.g. needle tip configurations with an abrupt angle formed between two adjacent sections
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06066Needles, e.g. needle tip configurations
    • A61B2017/0608J-shaped
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B50/00Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers
    • A61B50/30Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments
    • A61B2050/314Flexible bags or pouches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/08Muscles; Tendons; Ligaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0076Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof multilayered, e.g. laminated structures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0067Three-dimensional shapes conical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0069Three-dimensional shapes cylindrical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2240/00Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2240/00Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2240/001Designing or manufacturing processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00Materials or methods for coatings medical devices
    • A61L2420/04Coatings containing a composite material such as inorganic/organic, i.e. material comprising different phases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00Materials or methods for coatings medical devices
    • A61L2420/08Coatings comprising two or more layers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/10Materials or treatment for tissue regeneration for reconstruction of tendons or ligaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/32Materials or treatment for tissue regeneration for nerve reconstruction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C53/00Shaping by bending, folding, twisting, straightening or flattening; Apparatus therefor
    • B29C53/56Winding and joining, e.g. winding spirally
    • B29C53/58Winding and joining, e.g. winding spirally helically
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C53/00Shaping by bending, folding, twisting, straightening or flattening; Apparatus therefor
    • B29C53/56Winding and joining, e.g. winding spirally
    • B29C53/58Winding and joining, e.g. winding spirally helically
    • B29C53/60Winding and joining, e.g. winding spirally helically using internal forming surfaces, e.g. mandrels
    • B29C53/62Winding and joining, e.g. winding spirally helically using internal forming surfaces, e.g. mandrels rotatable about the winding axis
    • B29C53/66Winding and joining, e.g. winding spirally helically using internal forming surfaces, e.g. mandrels rotatable about the winding axis with axially movable winding feed member, e.g. lathe type winding
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2535/00Medical equipment, e.g. bandage, prostheses, catheter
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/249921Web or sheet containing structurally defined element or component
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2913Rod, strand, filament or fiber
    • Y10T428/2933Coated or with bond, impregnation or core
    • Y10T428/2938Coating on discrete and individual rods, strands or filaments
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T442/00Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
    • Y10T442/30Woven fabric [i.e., woven strand or strip material]
    • Y10T442/3065Including strand which is of specific structural definition

Abstract

The disclosure describes methods of winding collagen fiber to make medical constructs and related collagen fiber tube and patch devices.
PCT/US2009/005542 2008-10-09 2009-10-09 Methods of making collagen fiber medical constructs and related medical constructs, including nerve guides and patches WO2010042207A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA2740009A CA2740009C (en) 2008-10-09 2009-10-09 Methods of making collagen fiber medical constructs and related medical constructs, including nerve guides and patches
EP09819572.0A EP2349364B1 (en) 2008-10-09 2009-10-09 Methods of making collagen fiber medical constructs and related medical constructs, including nerve guides and patches

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10399508P 2008-10-09 2008-10-09
US61/103,995 2008-10-09
US13816508P 2008-12-17 2008-12-17
US61/138,165 2008-12-17

Publications (2)

Publication Number Publication Date
WO2010042207A2 WO2010042207A2 (en) 2010-04-15
WO2010042207A3 true WO2010042207A3 (en) 2010-07-08

Family

ID=42099574

Family Applications (3)

Application Number Title Priority Date Filing Date
PCT/US2009/005542 WO2010042207A2 (en) 2008-10-09 2009-10-09 Methods of making collagen fiber medical constructs and related medical constructs, including nerve guides and patches
PCT/US2009/005540 WO2010042205A2 (en) 2008-10-09 2009-10-09 Methods of making biocomposite medical constructs and related constructs including artificial tissues, vessels and patches
PCT/US2011/039375 WO2011156319A2 (en) 2008-10-09 2011-06-07 Methods of making collagen fiber medical constructs and related medical constructs, including tubes for auto and/or allo-grafts

Family Applications After (2)

Application Number Title Priority Date Filing Date
PCT/US2009/005540 WO2010042205A2 (en) 2008-10-09 2009-10-09 Methods of making biocomposite medical constructs and related constructs including artificial tissues, vessels and patches
PCT/US2011/039375 WO2011156319A2 (en) 2008-10-09 2011-06-07 Methods of making collagen fiber medical constructs and related medical constructs, including tubes for auto and/or allo-grafts

Country Status (4)

Country Link
US (7) US9078775B2 (en)
EP (3) EP2349364B1 (en)
CA (4) CA2976265C (en)
WO (3) WO2010042207A2 (en)

Families Citing this family (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4596335B2 (en) * 2007-12-07 2010-12-08 東洋紡績株式会社 Method for manufacturing nerve regeneration induction tube
EP2349364B1 (en) * 2008-10-09 2017-04-12 MiMedx Group, Inc. Methods of making collagen fiber medical constructs and related medical constructs, including nerve guides and patches
EP2389204B1 (en) 2009-01-23 2019-07-03 Royal College of Surgeons in Ireland Layered scaffold suitable for osteochondral repair
US8858577B2 (en) 2010-05-19 2014-10-14 University Of Utah Research Foundation Tissue stabilization system
FR2962646B1 (en) 2010-07-16 2012-06-22 Sofradim Production PROSTHETIC WITH RADIO OPAQUE ELEMENT
US20120012771A1 (en) * 2010-07-16 2012-01-19 Lale Korkmaz Ball seat having collapsible helical seat
US8758374B2 (en) 2010-09-15 2014-06-24 University Of Utah Research Foundation Method for connecting nerves via a side-to-side epineurial window using artificial conduits
US8852214B2 (en) 2011-02-04 2014-10-07 University Of Utah Research Foundation System for tissue fixation to bone
CA2829339C (en) 2011-03-08 2018-10-16 Mimedx, Inc. Collagen fiber ribbons with integrated fixation sutures and methods of making the same
FR2977790B1 (en) 2011-07-13 2013-07-19 Sofradim Production PROSTHETIC FOR UMBILIC HERNIA
US20130178874A1 (en) * 2011-07-19 2013-07-11 Hilton Becker Composite implant
EP2747796B8 (en) * 2011-08-25 2018-12-26 Universität Zürich A device for repair surgery of cylindrical organs, particularly ruptured tendons
WO2013066619A1 (en) 2011-10-17 2013-05-10 University Of Utah Research Foundation Methods and devices for connecting nerves
US10842494B2 (en) 2011-10-17 2020-11-24 University Of Utah Research Foundation Methods and devices for connecting nerves
US9179994B2 (en) 2011-10-25 2015-11-10 Covidien Lp Implantable film/mesh composite
US9005308B2 (en) 2011-10-25 2015-04-14 Covidien Lp Implantable film/mesh composite for passage of tissue therebetween
WO2013067294A1 (en) * 2011-11-02 2013-05-10 Mimedx Group, Inc. Implantable collagen devices and related methods and systems of making same
WO2013070670A1 (en) 2011-11-10 2013-05-16 Lifecell Corporation Device for tendon and ligament treatment
US20130218125A1 (en) * 2012-02-16 2013-08-22 Covidien Lp Implantable Devices Including A Mesh And A Perforated Film
US20130331802A1 (en) * 2012-06-06 2013-12-12 Cory Collinge Wound Treatment Medium and Method of Packaging and Use
FR2992662B1 (en) 2012-06-28 2014-08-08 Sofradim Production KNIT WITH PICOTS
EP2867298A4 (en) * 2012-06-29 2016-01-20 Univ South Florida Biocompatible polyacrylate compositions and methods of use
FR2992547B1 (en) 2012-06-29 2015-04-24 Sofradim Production PROSTHETIC FOR HERNIA
US9644177B2 (en) * 2012-07-12 2017-05-09 Board Of Regents, The University Of Texas System Extracellular matrix films and methods of making and using same
EP2687188A1 (en) * 2012-07-20 2014-01-22 Le Centre National De La Recherche Scientifique Artificial tendon or ligament with varying stiffness along its length
US10130346B2 (en) * 2012-07-24 2018-11-20 Omrix Biopharmaceuticals Ltd. Device and method for the application of a curable fluid composition to a bodily organ
US11253252B2 (en) 2012-07-30 2022-02-22 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US10219804B2 (en) 2012-07-30 2019-03-05 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US11944531B2 (en) 2012-07-30 2024-04-02 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US11957334B2 (en) 2012-07-30 2024-04-16 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US9629632B2 (en) 2012-07-30 2017-04-25 Conextions, Inc. Soft tissue repair devices, systems, and methods
US10390935B2 (en) 2012-07-30 2019-08-27 Conextions, Inc. Soft tissue to bone repair devices, systems, and methods
US10835241B2 (en) 2012-07-30 2020-11-17 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US9427309B2 (en) 2012-07-30 2016-08-30 Conextions, Inc. Soft tissue repair devices, systems, and methods
US9943551B2 (en) 2012-08-15 2018-04-17 Mimedx Group, Inc. Tissue grafts composed of micronized placental tissue and methods of making and using the same
US20140186461A1 (en) 2012-09-10 2014-07-03 Alpha Tissue, Inc. Human Amniotic Membrane Lyophilized Grafts
US9180145B2 (en) 2012-10-12 2015-11-10 Mimedx Group, Inc. Compositions and methods for recruiting and localizing stem cells
US9155799B2 (en) 2012-11-19 2015-10-13 Mimedx Group, Inc. Cross-linked collagen with at least one bound antimicrobial agent for in vivo release of the agent
US8946163B2 (en) 2012-11-19 2015-02-03 Mimedx Group, Inc. Cross-linked collagen comprising metallic anticancer agents
US8940684B2 (en) 2012-11-19 2015-01-27 Mimedx Group, Inc. Cross-linked collagen comprising an antifungal agent
JP6545102B2 (en) 2013-01-18 2019-07-17 ミメディクス グループ インコーポレイテッド How to treat a cardiac condition
US10206977B1 (en) 2013-01-18 2019-02-19 Mimedx Group, Inc. Isolated placental stem cell recruiting factors
WO2014143925A1 (en) * 2013-03-15 2014-09-18 New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Carbon nanotubes and graphene patches and implants for biological tissue
US10029030B2 (en) 2013-03-15 2018-07-24 Mimedx Group, Inc. Molded placental tissue compositions and methods of making and using the same
US10335433B2 (en) 2013-04-10 2019-07-02 Mimedx Group, Inc. NDGA polymers and metal complexes thereof
US9446142B2 (en) 2013-05-28 2016-09-20 Mimedx Group, Inc. Polymer chelator conjugates
JP6455427B2 (en) * 2013-06-28 2019-01-23 国立大学法人佐賀大学 Patch-type artificial skin preparation
WO2015031681A1 (en) 2013-08-30 2015-03-05 Mimedx Group, Inc. Micronized placental compositions comprising a chelator
EP3085394B1 (en) * 2013-12-16 2018-02-28 Eisai R&D Management Co., Ltd. Revascularization graft material
EP3094336A4 (en) 2014-01-17 2018-02-14 MIMEDX Group Inc. Method for inducing angiogenesis
US9949819B2 (en) * 2014-02-13 2018-04-24 Antonio Sambusseti Non-absorbable tissue reconstruction device, in particular for tissues such as ligaments
CA2941418A1 (en) * 2014-03-11 2015-09-17 Antonio Sambusseti Absorbable tissue reconstruction device, in particular for tissues such as ligaments
US11583384B2 (en) 2014-03-12 2023-02-21 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
CN106457419B (en) 2014-03-17 2019-09-13 盛邦直接植入国际有限责任公司 Bore caging system and its application method
EP3139972B1 (en) * 2014-05-08 2020-04-29 The Secant Group, LLC Composite lumen with reinforcing textile and matrix
WO2016036833A1 (en) * 2014-09-02 2016-03-10 Rutgers, The State University Of New Jersey Biocompatible textile sleeves to support and guide muscle regeneration and methods of use thereof
CN104921841B (en) * 2015-04-10 2017-03-29 南开大学 A kind of preparation method of double-decker artificial blood vessel
US10413635B2 (en) * 2015-08-17 2019-09-17 Vivex Biomedical, Inc. Umbilical cord transplant product
CN106480607A (en) * 2015-08-24 2017-03-08 上海微创医疗器械(集团)有限公司 Static spinning membrane, the preparation method of static spinning membrane and composite membrane
US11913166B2 (en) 2015-09-21 2024-02-27 Modern Meadow, Inc. Fiber reinforced tissue composites
US10675016B2 (en) 2015-10-30 2020-06-09 New York Society For The Relief Of The Ruptured And Crippled, Maintaining The Hospital For Special Surgery Suture sleeve patch and methods of delivery within an existing arthroscopic workflow
US11523812B2 (en) 2016-02-01 2022-12-13 Medos International Sarl Soft tissue fixation repair methods using tissue augmentation constructs
US11484401B2 (en) 2016-02-01 2022-11-01 Medos International Sarl Tissue augmentation scaffolds for use in soft tissue fixation repair
BR112017016266A2 (en) 2016-02-15 2018-03-27 Modern Meadow, Inc. method for producing a biofabricated material.
WO2017147431A1 (en) * 2016-02-24 2017-08-31 Georgia Tech Research Corporation Surgical suture materials with porous sheaths for drug delivery
CA3015510A1 (en) 2016-02-25 2017-08-31 The Secant Group, Llc Composite containing poly(glycerol sebacate) filler
US11696822B2 (en) 2016-09-28 2023-07-11 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
CA3057869A1 (en) 2017-03-31 2018-10-04 The Secant Group, Llc Cured biodegradable microparticles and scaffolds and methods of making and using the same
CN107385577B (en) * 2017-08-22 2019-06-25 安徽佳元工业纤维有限公司 The method of multi cord first twist differentiation is realized on a kind of two-for-one twister
US11065099B2 (en) 2017-10-06 2021-07-20 The Secant Group, Llc Flexible hollow lumen composite
AU2018253595A1 (en) 2017-11-13 2019-05-30 Modern Meadow, Inc. Biofabricated leather articles having zonal properties
US11547397B2 (en) 2017-12-20 2023-01-10 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
AU2019223962A1 (en) 2018-02-20 2020-09-10 Conextions, Inc. Devices, systems, and methods for repairing soft tissue and attaching soft tissue to bone
US11589973B2 (en) 2018-05-16 2023-02-28 Mimedx Group, Inc. Methods of making collagen fiber medical constructs and related medical constructs, including patches
GB201808106D0 (en) * 2018-05-18 2018-07-04 Cambridge Entpr Ltd Collagen biomaterials and methods for manufacturing collagen biomaterials
EP3595589A1 (en) * 2018-05-21 2020-01-22 Aran Biomedical Teoranta Insertable medical devices with low profile composite coverings
US11583609B2 (en) * 2018-08-08 2023-02-21 Mimedx Group, Inc. Collagen constructs and methods of making the same
EP3628763B1 (en) * 2018-09-27 2021-06-02 Sofradim Production Bioresorbable knit for hernia repair and method for manufacturing the same
US20200129435A1 (en) * 2018-10-24 2020-04-30 Uvic Industry Partnerships Inc. Composition for delivering a therapeutic agent and methods for making and using
WO2020147733A1 (en) * 2019-01-16 2020-07-23 武汉杨森生物技术有限公司 Method for preparing material for artificial blood vessel, artificial blood vessel prepared thereby and application thereof
EP3704202A4 (en) 2019-01-17 2020-12-16 Modern Meadow, Inc. Layered collagen materials and methods of making the same
WO2021035679A1 (en) * 2019-08-30 2021-03-04 江南大学 Tissue engineered nerve graft and preparation method therefor
JP2023500562A (en) * 2019-09-25 2023-01-10 カンヌフロウ インコーポレイテッド Method and apparatus for implanting biological constructs
KR20220123658A (en) * 2019-12-09 2022-09-08 모던 메도우 아이엔씨. Leather-Like Materials Including Melt-Blended Collagen and Thermoplastic Polymers
EP3854349A1 (en) * 2020-01-23 2021-07-28 Kardiozis SAS Endoprosthesis and method of manufacturing an endoprosthesis
EP3854348A1 (en) * 2020-01-23 2021-07-28 Kardiozis SAS Endoprosthesis and method of attaching a fiber to a surface
CN115135280A (en) * 2020-02-18 2022-09-30 史密夫和内修有限公司 Bioactive scaffold augmentation for anterior cruciate ligament reconstruction
US11471264B2 (en) * 2020-04-01 2022-10-18 Medtronic Vascular, Inc. Branching stent graft with mechanical interlock
US20230389926A1 (en) * 2020-10-16 2023-12-07 The Johns Hopkins University Biodegradable nanofiber conical conduits for nerve repair
AU2021387812A1 (en) * 2020-11-30 2023-06-22 Embody, Inc. Micropost array apparatus and biocompatible scaffold
CN113045645B (en) * 2021-03-15 2024-03-22 张梦蝶 Raw pigskin collagen fiber extraction element of medical treatment usefulness
EP4082448A1 (en) * 2021-04-26 2022-11-02 Tissium SA Nerve conduit
WO2023080894A1 (en) * 2021-11-04 2023-05-11 Upside Foods, Inc. Substrate apparatus with multi-layer substrate for cell-based meat cultivators
WO2024044026A1 (en) * 2022-08-26 2024-02-29 Checkpoint Surgical, Inc. Chitosan tubular member and method of producing
WO2024078716A1 (en) * 2022-10-12 2024-04-18 Tissium S.A. Nerve conduit

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6596296B1 (en) * 1999-08-06 2003-07-22 Board Of Regents, The University Of Texas System Drug releasing biodegradable fiber implant
US20050009178A1 (en) * 2003-06-04 2005-01-13 University Of South Carolina Tissue scaffold having aligned fibrils, apparatus and method for producing the same, and artificial tissue and methods of use thereof
US7135040B2 (en) * 2002-12-23 2006-11-14 Agency For Science, Technology And Research Medical guide tubes
US20070269481A1 (en) * 2006-01-27 2007-11-22 The Regents Of The University Of California Biomimetic Scaffolds

Family Cites Families (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1104051A (en) * 1963-10-16 1968-02-21 Klinger Mfg Co Ltd Improvements in or relating to false twisting apparatus
US3700489A (en) * 1970-07-30 1972-10-24 Ethicon Inc Process for applying a thin coating of polytetrafluoroethylene
US3791388A (en) * 1971-09-22 1974-02-12 Ethicon Inc Covered suture
GB2084468B (en) * 1980-09-25 1984-06-06 South African Inventions Surgical implant
WO1982001647A1 (en) 1980-11-17 1982-05-27 Robert L Kaster Vascular graft
FR2559666B1 (en) * 1984-02-21 1986-08-08 Tech Cuir Centre PROCESS FOR THE MANUFACTURE OF COLLAGEN TUBES, ESPECIALLY LOW-DIAMETER TUBES, AND APPLICATION OF THE TUBES OBTAINED IN THE FIELD OF VASCULAR PROSTHESES AND NERVOUS SUTURES
US4837285A (en) * 1984-03-27 1989-06-06 Medimatrix Collagen matrix beads for soft tissue repair
US4778467A (en) 1984-04-25 1988-10-18 The University Of Utah Prostheses and methods for promoting nerve regeneration and for inhibiting the formation of neuromas
US4792336A (en) 1986-03-03 1988-12-20 American Cyanamid Company Flat braided ligament or tendon implant device having texturized yarns
US5263984A (en) 1987-07-20 1993-11-23 Regen Biologics, Inc. Prosthetic ligaments
US5078744A (en) 1987-09-04 1992-01-07 Bio-Products, Inc. Method of using tendon/ligament substitutes composed of long, parallel, non-antigenic tendon/ligament fibers
DE3884743T2 (en) 1987-10-30 1994-01-27 Howmedica Device for restoring a tendon or ligament.
ES2060614T3 (en) * 1988-03-11 1994-12-01 Chemokol G B R Ing Buro Fur Ko PROCEDURE FOR THE MANUFACTURE OF COLLAGEN MEMBRANES FOR HEMOSTASIS, WOUND TREATMENT AND IMPLANTS.
US4883486A (en) 1988-05-31 1989-11-28 Indu Kapadia Prosthetic ligament
US5162430A (en) * 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
US5106949A (en) * 1989-09-15 1992-04-21 Organogenesis, Inc. Collagen compositions and methods for preparation thereof
US5256418A (en) 1990-04-06 1993-10-26 Organogenesis, Inc. Collagen constructs
US5378469A (en) * 1990-04-06 1995-01-03 Organogenesis, Inc. Collagen threads
CA2704197C (en) * 1990-12-13 2011-01-04 United States Surgical Corporation Method and apparatus for tipping sutures
US5656605A (en) 1994-01-26 1997-08-12 Institute Of Molecular Biology, Inc. Device to promote drug-induced nerve regeneration
EP0793512A1 (en) 1994-11-07 1997-09-10 University Of Medicine And Dentistry Of New Jersey Synthetic collagen orthopaedic structures such as grafts, tendons and other structures
US5713374A (en) 1995-02-10 1998-02-03 The Hospital For Joint Diseases Orthopaedic Institute Fixation method for the attachment of wound repair materials to cartilage defects
US5900245A (en) 1996-03-22 1999-05-04 Focal, Inc. Compliant tissue sealants
US5718012A (en) * 1996-05-28 1998-02-17 Organogenesis, Inc. Method of strength enhancement of collagen constructs
US5718717A (en) 1996-08-19 1998-02-17 Bonutti; Peter M. Suture anchor
TW501934B (en) 1996-11-20 2002-09-11 Tapic Int Co Ltd Collagen material and process for making the same
TW528600B (en) * 1996-11-20 2003-04-21 Yasuhiko Shimizu Artificial neural canal
FR2755846B1 (en) 1996-11-20 1998-12-31 Jacques Philippe Laboureau PRE-ORIENT PROSTHETIC LIGAMENT AND METHOD OF MAKING
ES2238736T3 (en) * 1996-12-03 2005-09-01 Osteobiologics, Inc. BIODEGRADABLE POLYMER FILM.
US6083522A (en) 1997-01-09 2000-07-04 Neucoll, Inc. Devices for tissue repair and methods for preparation and use thereof
CN1264390A (en) * 1997-05-28 2000-08-23 清水庆彦 Collagen gel
US6245103B1 (en) 1997-08-01 2001-06-12 Schneider (Usa) Inc Bioabsorbable self-expanding stent
US6420625B1 (en) 1997-09-12 2002-07-16 Kimberly-Clark Worldwide, Inc. Breathable, liquid-impermeable, apertured film/nonwoven laminate and process for making same
US6224630B1 (en) * 1998-05-29 2001-05-01 Advanced Bio Surfaces, Inc. Implantable tissue repair device
WO1999063908A1 (en) 1998-06-10 1999-12-16 Tapic International Co., Ltd. Artificial neural tube
EP1098024A4 (en) * 1998-06-11 2008-04-02 Yasuhiko Shimizu Collagen material and process for producing the same
US20020165611A1 (en) 1998-12-22 2002-11-07 Robert-Jan Enzerink Graft material convenience package
EP1022031B1 (en) * 1999-01-21 2005-03-23 Nipro Corporation Suturable adhesion-preventing membrane
US7615373B2 (en) * 1999-02-25 2009-11-10 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed collagen and tissue engineering
US6592623B1 (en) 1999-08-31 2003-07-15 Virginia Commonwealth University Intellectual Property Foundation Engineered muscle
US6391333B1 (en) * 1999-04-14 2002-05-21 Collagen Matrix, Inc. Oriented biopolymeric membrane
US6964685B2 (en) 1999-06-22 2005-11-15 The Brigham And Women's Hospital, Inc. Biologic replacement for fibrin clot
WO2001006045A1 (en) * 1999-07-14 2001-01-25 Kaneka Corporation Regenerated collagen fiber with excellent heat resistance
US6936072B2 (en) 1999-08-18 2005-08-30 Intrinsic Therapeutics, Inc. Encapsulated intervertebral disc prosthesis and methods of manufacture
ATE297229T1 (en) * 1999-08-31 2005-06-15 Univ Virginia Commonwealth RECONSTRUCTED MUSCLE
CA2285161A1 (en) 1999-10-06 2001-04-06 1218122 Ontario Inc. In vitro cultured ligament tissue and method of making same
US6645247B2 (en) * 1999-10-08 2003-11-11 Bret A. Ferree Supplementing engineered annulus tissues with autograft of allograft tendons
US20030035786A1 (en) * 1999-11-04 2003-02-20 Medtronic, Inc. Biological tissue adhesives, articles, and methods
US6292697B1 (en) 2000-02-15 2001-09-18 Medtronic, Inc. Testing sterile packaged components of an implantable medical device prior to chronic implantation
AR027685A1 (en) * 2000-03-22 2003-04-09 Synthes Ag METHOD AND METHOD FOR CARRYING OUT
DE60132079T2 (en) 2000-03-24 2008-12-18 Drexel University Process for the preparation of a replacement construct for ligaments
US6565960B2 (en) 2000-06-01 2003-05-20 Shriners Hospital Of Children Polymer composite compositions
US6692528B2 (en) * 2000-11-09 2004-02-17 The Polymer Technology Group Incorporated Devices that change size/shape via osmotic pressure
US6752831B2 (en) * 2000-12-08 2004-06-22 Osteotech, Inc. Biocompatible osteogenic band for repair of spinal disorders
US20040110439A1 (en) * 2001-04-20 2004-06-10 Chaikof Elliot L Native protein mimetic fibers, fiber networks and fabrics for medical use
JP3871525B2 (en) * 2001-04-26 2007-01-24 ニプロ株式会社 Biological tissue or organ regeneration device
US6445247B1 (en) * 2001-06-01 2002-09-03 Qualcomm Incorporated Self-controlled high efficiency power amplifier
US20030003157A1 (en) * 2001-06-06 2003-01-02 University Of Medicine & Dentistry Of New Jersey Collagen compositions and methods for making and using the same
US6596096B2 (en) * 2001-08-14 2003-07-22 General Electric Company Permanent magnet for electromagnetic device and method of making
US6902932B2 (en) * 2001-11-16 2005-06-07 Tissue Regeneration, Inc. Helically organized silk fibroin fiber bundles for matrices in tissue engineering
US6899981B1 (en) 2001-11-21 2005-05-31 Dupont Photomasks, Inc. Photomask and method for detecting violations in a mask pattern file using a manufacturing rule
US7048963B2 (en) * 2001-11-30 2006-05-23 Cambridge Polymers Group, Inc. Layered aligned polymer structures and methods of making same
US20030114061A1 (en) * 2001-12-13 2003-06-19 Kazuhisa Matsuda Adhesion preventive membrane, method of producing a collagen single strand, collagen nonwoven fabric and method and apparatus for producing the same
AU2003219916A1 (en) * 2002-02-22 2003-09-09 University Of Washington Bioengineered tissue substitutes
US6730124B2 (en) 2002-03-08 2004-05-04 Musculoskeletal Transplant Foundation Bone-tendon-bone assembly with cancellous allograft bone block
US7514249B2 (en) * 2002-04-18 2009-04-07 The University Of Florida Research Foundation, Inc. Biomimetic organic/inorganic composites
US7105021B2 (en) 2002-04-25 2006-09-12 Scimed Life Systems, Inc. Implantable textile prostheses having PTFE cold drawn yarns
US20030230316A1 (en) 2002-06-18 2003-12-18 Glucksman Dov Z. Battery operated hair braider
US7309359B2 (en) * 2003-08-21 2007-12-18 Warsaw Orthopedic, Inc. Allogenic/xenogenic implants and methods for augmenting or repairing intervertebral discs
US7090690B2 (en) 2002-11-19 2006-08-15 Arthrocare Corporation Devices and methods for repairing soft tissue
US7264859B2 (en) * 2002-12-19 2007-09-04 Kimberly-Clark Worldwide, Inc. Lubricious coating for medical devices
JP4605985B2 (en) * 2002-12-27 2011-01-05 ニプロ株式会社 Nerve regeneration induction tube
US8226715B2 (en) 2003-06-30 2012-07-24 Depuy Mitek, Inc. Scaffold for connective tissue repair
EP1682161A4 (en) 2003-10-29 2011-12-07 Gentis Inc Polymerizable emulsions for tissue engineering
FR2865380B1 (en) 2004-01-23 2006-03-03 L A R S Laboratoire D Applic E METHOD FOR ATTACHING TRACTION WIRES TO THE END OF A PROTHETIC LIGAMENT
US20070230316A1 (en) * 2004-03-29 2007-10-04 Yoshimi Tomita Information Recording Medium, Information Reproducing Apparatus and Method, Information Recording Apparatus and Method, and Computer Program
US7595282B2 (en) * 2004-05-20 2009-09-29 Halliburton Energy Services, Inc. Methods and compositions of controlling the rheology of a diutan-containing well treatment fluid at high temperatures
CN101044284B (en) * 2004-10-19 2010-12-01 东京制纲株式会社 Cable composed of high strength fiber composite material
US20060095134A1 (en) * 2004-10-28 2006-05-04 Sdgi Holdings, Inc. Materials, devices and methods for implantation of transformable implants
US7354627B2 (en) * 2004-12-22 2008-04-08 Depuy Products, Inc. Method for organizing the assembly of collagen fibers and compositions formed therefrom
US20060200250A1 (en) 2005-03-04 2006-09-07 Ku David N Biocompatible implant device
US8728463B2 (en) * 2005-03-11 2014-05-20 Wake Forest University Health Science Production of tissue engineered digits and limbs
KR20080008364A (en) * 2005-05-05 2008-01-23 헤모텍 아게 All-over coating of vessel stents
US8048446B2 (en) * 2005-05-10 2011-11-01 Drexel University Electrospun blends of natural and synthetic polymer fibers as tissue engineering scaffolds
US20070038290A1 (en) * 2005-08-15 2007-02-15 Bin Huang Fiber reinforced composite stents
US8782436B2 (en) * 2006-05-31 2014-07-15 International Business Machines Corporation Method and system for transformation of logical data objects for storage
CA2656044C (en) * 2006-06-22 2015-10-20 University Of South Florida Collagen scaffolds, medical implants with same and methods of use
US8093027B2 (en) * 2006-09-13 2012-01-10 University Of South Florida Method for producing biocomposite comprising collagen and polymer
WO2008041183A2 (en) 2006-10-05 2008-04-10 Technion Research & Development Foundation Ltd. Microtubes and methods of producing same
EP2111240B1 (en) * 2006-12-27 2012-08-08 Shriners Hospitals for Children Methods of making high-strength ndga polymerized collagen fibers and related medical devices and constructs
WO2008093342A2 (en) 2007-02-01 2008-08-07 Technion Research & Development Foundation Ltd. Albumin fibers and fabrics and methods of generating and using same
AU2008219006B2 (en) 2007-02-20 2013-04-18 Shriners Hospitals For Children In vivo hydraulic fixation including bio-rivets using biocompatible expandable fibers
ES2744388T3 (en) * 2007-03-20 2020-02-24 Allergan Inc Tendon prostheses and manufacturing method
US20080286332A1 (en) 2007-05-14 2008-11-20 Pacetti Stephen D Implantable medical devices with a topcoat layer of phosphoryl choline acrylate polymer for reduced thrombosis, and improved mechanical properties
US9681869B2 (en) 2008-02-22 2017-06-20 Mimedx Group, Inc. Biostaples suitable for wrist, hand and other ligament replacements or repairs
US9216077B2 (en) * 2008-05-16 2015-12-22 Mimedx Group, Inc. Medical constructs of twisted lengths of collagen fibers and methods of making same
US8480686B2 (en) * 2008-09-25 2013-07-09 Ethicon Endo-Surgery, Inc. Methods and devices for delivering and applying suture anchors
EP2349364B1 (en) 2008-10-09 2017-04-12 MiMedx Group, Inc. Methods of making collagen fiber medical constructs and related medical constructs, including nerve guides and patches

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6596296B1 (en) * 1999-08-06 2003-07-22 Board Of Regents, The University Of Texas System Drug releasing biodegradable fiber implant
US7135040B2 (en) * 2002-12-23 2006-11-14 Agency For Science, Technology And Research Medical guide tubes
US20050009178A1 (en) * 2003-06-04 2005-01-13 University Of South Carolina Tissue scaffold having aligned fibrils, apparatus and method for producing the same, and artificial tissue and methods of use thereof
US20070269481A1 (en) * 2006-01-27 2007-11-22 The Regents Of The University Of California Biomimetic Scaffolds

Also Published As

Publication number Publication date
CA2740008A1 (en) 2010-04-15
EP2349364B1 (en) 2017-04-12
CA2976265A1 (en) 2010-04-15
WO2010042205A2 (en) 2010-04-15
EP2575911A4 (en) 2016-02-10
EP2349364A2 (en) 2011-08-03
US9801978B2 (en) 2017-10-31
EP2349363A2 (en) 2011-08-03
CA2806396A1 (en) 2011-12-15
US20100094318A1 (en) 2010-04-15
CA2740009C (en) 2017-09-26
CA2806396C (en) 2019-01-08
US9078775B2 (en) 2015-07-14
US9125759B2 (en) 2015-09-08
WO2010042207A2 (en) 2010-04-15
US20110282448A1 (en) 2011-11-17
CA2976265C (en) 2019-03-19
US20100094404A1 (en) 2010-04-15
WO2011156319A3 (en) 2012-04-12
US20180177921A1 (en) 2018-06-28
EP2575911A2 (en) 2013-04-10
EP2575911B1 (en) 2019-03-06
US10238773B2 (en) 2019-03-26
US9179976B2 (en) 2015-11-10
US20130131781A1 (en) 2013-05-23
CA2740008C (en) 2017-01-31
EP2349364A4 (en) 2013-10-30
US20150283305A1 (en) 2015-10-08
US20160022874A1 (en) 2016-01-28
EP2349363B1 (en) 2018-12-05
CA2740009A1 (en) 2010-04-15
WO2010042205A3 (en) 2010-07-22
WO2011156319A2 (en) 2011-12-15
US8367148B2 (en) 2013-02-05
EP2349363A4 (en) 2013-11-06

Similar Documents

Publication Publication Date Title
WO2010042207A3 (en) Methods of making collagen fiber medical constructs and related medical constructs, including nerve guides and patches
EP3800197B8 (en) Tissue plug
WO2010043980A3 (en) Surgical patch
EP2291143A4 (en) Medical constructs of twisted lengths of collagen fibers and methods of making same
WO2010019753A3 (en) Tissue scaffolds
IL220903A0 (en) Bioengineered tissue constructs and methods for producing and using thereof
EP2667810A4 (en) Ultrasonic surgical instrument, associated surgical method and related manufacturing method
WO2012082517A3 (en) Controlled degradation fibers
EP2584975A4 (en) Endoscopic suturing device, system and method
EP2303144A4 (en) Endoscopic suturing system
WO2011143206A3 (en) Porous materials, methods of making and uses
GB0819912D0 (en) Tubular implantable cord
EP2452673A4 (en) Chitosan gel for dermatological use, production method therefor and use of same
WO2011133504A3 (en) Nanozymes, methods of making nanozymes, and methods of using nanozymes
EP2335554A4 (en) Medical system, out-of-body device of the medical system, capsule medical device of the medical system, and antennal switching method of the capsule medical device
EP2344049A4 (en) Implantable prosthesis
EP2644757A4 (en) Hollow fiber membrane spinning nozzle, and method for manufacturing hollow fiber membrane
WO2010065743A3 (en) Bicyclic compounds and methods of making and using same
WO2009146099A3 (en) Contrast agents, methods for preparing contrast agents, and methods of imaging
EP2269981A4 (en) Vinylsulfonic acid, polymer of the same, and method for producing the same
EP2402501A4 (en) Artificial leather, entangled web of long fibers, and processes for producing these
EP2613187A4 (en) Optical transmission body, method for producing same, and optical transmission module
BRPI1016020A2 (en) surgical line comprising cells and method of producing the line.
WO2011003103A3 (en) Pharmacology of visual cycle modulators
EP2629830A4 (en) Catheter patch applicator assembly

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 09819572

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 2740009

Country of ref document: CA

NENP Non-entry into the national phase

Ref country code: DE

REEP Request for entry into the european phase

Ref document number: 2009819572

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2009819572

Country of ref document: EP