WO2010039817A4 - System and method for wire-guided pedicle screw stabilization of spinal vertebrae - Google Patents

System and method for wire-guided pedicle screw stabilization of spinal vertebrae Download PDF

Info

Publication number
WO2010039817A4
WO2010039817A4 PCT/US2009/059004 US2009059004W WO2010039817A4 WO 2010039817 A4 WO2010039817 A4 WO 2010039817A4 US 2009059004 W US2009059004 W US 2009059004W WO 2010039817 A4 WO2010039817 A4 WO 2010039817A4
Authority
WO
WIPO (PCT)
Prior art keywords
rod
screw
flexible connector
screw head
guide
Prior art date
Application number
PCT/US2009/059004
Other languages
French (fr)
Other versions
WO2010039817A2 (en
WO2010039817A3 (en
Inventor
Sherwin Hua
Original Assignee
Sherwin Hua
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sherwin Hua filed Critical Sherwin Hua
Priority to CN200980140693.1A priority Critical patent/CN102186433B/en
Priority to EP09818436.9A priority patent/EP2341858B1/en
Priority to CA2739431A priority patent/CA2739431C/en
Priority to KR1020117009465A priority patent/KR101679088B1/en
Priority to JP2011530168A priority patent/JP5795534B2/en
Priority to ES09818436.9T priority patent/ES2462759T3/en
Priority to AU2009298554A priority patent/AU2009298554B2/en
Priority to US13/122,388 priority patent/US8556940B2/en
Priority to BRPI0920821A priority patent/BRPI0920821B8/en
Priority to RU2011113701/14A priority patent/RU2513155C2/en
Priority to MX2011003046A priority patent/MX345890B/en
Priority to PCT/US2010/029199 priority patent/WO2011040986A1/en
Publication of WO2010039817A2 publication Critical patent/WO2010039817A2/en
Publication of WO2010039817A3 publication Critical patent/WO2010039817A3/en
Publication of WO2010039817A4 publication Critical patent/WO2010039817A4/en
Priority to US13/082,346 priority patent/US8721691B2/en
Priority to US13/098,325 priority patent/US8545541B2/en
Priority to US13/189,432 priority patent/US10973551B2/en
Priority to US13/245,227 priority patent/US8333770B2/en
Priority to US13/246,432 priority patent/US8216282B2/en
Priority to AU2016201395A priority patent/AU2016201395B2/en
Priority to AU2017245407A priority patent/AU2017245407B2/en
Priority to AU2019210492A priority patent/AU2019210492A1/en
Priority to US17/025,815 priority patent/US11759238B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7001—Screws or hooks combined with longitudinal elements which do not contact vertebrae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7001—Screws or hooks combined with longitudinal elements which do not contact vertebrae
    • A61B17/7002—Longitudinal elements, e.g. rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7001—Screws or hooks combined with longitudinal elements which do not contact vertebrae
    • A61B17/7002—Longitudinal elements, e.g. rods
    • A61B17/701—Longitudinal elements with a non-circular, e.g. rectangular, cross-section
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7053—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant with parts attached to bones or to each other by flexible wires, straps, sutures or cables
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7074—Tools specially adapted for spinal fixation operations other than for bone removal or filler handling
    • A61B17/7083—Tools for guidance or insertion of tethers, rod-to-anchor connectors, rod-to-rod connectors, or longitudinal elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84—Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86—Pins or screws or threaded wires; nuts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/8863—Apparatus for shaping or cutting osteosynthesis equipment by medical personnel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/90—Identification means for patients or instruments, e.g. tags
    • A61B90/92—Identification means for patients or instruments, e.g. tags coded with colour
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/392—Radioactive markers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3937—Visible markers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3937—Visible markers
    • A61B2090/3941—Photoluminescent markers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3954—Markers, e.g. radio-opaque or breast lesions markers magnetic, e.g. NMR or MRI
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3966—Radiopaque markers visible in an X-ray image

Abstract

An improved system and method for positioning screws and rods to immobilize bones is provided. Specifically, the system and method is optimal for performing transforaminal lumbar interbody fusion (TLIF) and other interbody fusions in the spine. The system involves pedicle screws detachably connected to wires that guide rods down to the screws. The wires are strong, narrow, flexible, adjustable in tension, and easily disconnected from the screws after rod placement via a process such as cutting, radiating, burning, dissolving, etc.. The use of wires to place the rods avoids the conventional bulky tower apparatuses of the prior art while at the same time enhancing the accuracy of placement. One of the preferred methods involves relying upon the natural lordotic curvature of the spine and the narrow diameter of the wires to insert many elements through a single minimally invasive incision.

Claims

AMENDED CLAIMS received by the International Bureau on 09 July 2010 (09.07.2010)
1. An apparatus for guiding a rod or flexible connector into a screw head, configured to: (i) accept a large degree of malalignment of the rod or flexible connector and the screw head;
(ii) guide the screw head and the rod or flexible connector into alignment; and (iii) lock the rod or flexible connector into the screw head by a locking mechanism.
2. The apparatus of claim 1, especially adapted for fusing together or stabilizing at least two lumbar vertebrae, comprising: at least two screws, each screw having, a head with a seat and a downwardly directed shaft; at least one rod or flexible connector, at least two locking assemblies to lock the rod or flexible connector into each screw head; at least one upwardly directed guide wire and/or guide shaft for each screw; wherein the upwardly directed guide wire and/or guide shaft is connected to the screw head or downwardly directed screw shaft when the screw is inserted into a vertebrae, and is also disconnectable from the screw head or downwardly directed screw shaft, including after the screw has been inserted and the rod or flexible connector has been locked in place in the screw head; wherein the rod or flexible connector is configured to be guided by the upwardly directed guide wire(s) and/or guide shaft(s) until the rod or flexible connector is inserted into the seats of the screw heads.
3. The apparatus of claim 2, wherein each locking assembly is configured to be guided by the upwardly directed guide wire(s) and/or guide shaft(s) until the locking assembly is attached to the screw head and tightened to lock the rod or flexible connector into position.
4. The apparatus of claim 2, wherein each locking assembly is part of a screw head that can be manipulated to trap the rod or flexible connector.
5. The apparatus of claim 4, wherein each locking assembly that is part of a screw head snaps into place to trap the rod or flexible connector.
6. The apparatus of claim 2, further comprising an extended tab positioned between and attached to both (i) the upwardly directed guide wire and/or guide shaft and (ii) the screw head or downwardly directed screw shaft; such that (i) the upwardly directed guide wire and/or guide shaft and (ii) the screw head or downwardly directed screw shaft, are connected to each other through the extended tab; wherein the extended tab is adapted to be easily detached from the screw head or downwardly directed screw shaft, thereby also disconnecting the upwardly directed guide wire and/or guide shaft from the screw head or downwardly directed screw shaft as it is detached.
7. The apparatus of claim 6, wherein the extended tab has screw threads.
8. The apparatus of claim 6, wherein the extended tab is easily detached by snapping off.
9. The apparatus of claim 2, further comprising: one or more instrument(s) for manipulating the rod or flexible connector and the screw(s) with respect to one another; and one or more retractor(s), for holding muscle and tissue apart during insertion of the rod or flexible connector and locking assemblies, or for accessing other structures of a spine, as in a laminectomy, discectomy, or interbody fusion;
44 wherein the instrument(s) are guided by the upwardly directed guide wire(s) and/or guide shaft(s) until the rod or flexible connector is securely locked into the screw head(s) by the locking assemblies; and wherein the retractor(s) are also guided by the upwardly directed guide wire(s) and/or guide shaft(s) and optionally, held in place by them.
10. The apparatus of claim 9, further comprising: one or more instrument(s) for inserting the rod or flexible connector into the screw heads; one or more instrument(s) for inserting the locking assemblies into the screw heads above the rod or flexible connector; one or more instrument(s) for adjusting an angle and an orientation of the screw heads; one or more instrument(s) for confirming that the rod or flexible connector is within the screw heads; one or more instrument(s) for capturing the screw heads in order to advance, withdraw, or remove the screw(s); one or more instruments) for compressing or distracting the vertebrae using the screws or screw heads; one or more instruments) for reducing vertebrae that are dislocated or spondylolisthesis using screws or screw heads; or one or more instrument(s) for tightening or locking the locking assemblies to secure the rod or flexible connector within the screw heads; wherein any above instrument can perform more than one of the above functions and wherein the instrument(s) is guided by the upwardly directed guide wire(s) and/or guide shaft(s).
11. The apparatus of claim 2, wherein each screw has at least two upwardly directed guide wires.
45
12. The apparatus of claim 2, wherein each screw has multiple (more than one) upwardly directed short wires attached to the screw head and each short wire is then connected to one or more upwardly directed long wire(s).
13. The apparatus of claim 12, wherein the multiple short wires are connected to an inner edge on the screw head, leaving space therein for the rod or flexible connector to sit.
14. The apparatus of claim 2, wherein a cross-section of each screw head has a concave shape that forms a channel in which the rod or flexible connector sits.
15. The apparatus of claim 14, wherein each screw head has upper edges and further comprising flanged arms, attached to or formed from the upper edges of the screw head, the flanged arms being configured to receive an incoming rod or flexible connector at a wide range of angles.
16. The apparatus of claim 2, wherein each screw head has an upwardly directed shaft attached thereto and the upwardly directed shaft has a non-circular shape configured to engage a complementary non-circular shape on another element such that the other element can be moved closer to the screw without rotation.
17. The apparatus of claim 16, wherein the other element is an insertion tool or a rod or flexible connector.
18. The apparatus of claim 2, wherein the seat of each screw head is in a center of the screw head, in which the rod or flexible connector is inserted, and on each of two opposite sides of the seat is a wall and each wall or an extension thereof is highest in a center of it and lowest on edges of it, thereby configured to allow a malaligned or rotated rod or flexible connector or screw head to come together and slowly conform to one another as the rod or flexible connector is inserted into the seat of the screw head.
19. The apparatus of claim 18, wherein the walls or extensions thereof ate downwardly tapered and symmetrically convex.
20. The apparatus of claim 2, wherein the seat of each screw head is in a center of the screw head, in which the rod or flexible connector is inserted, and on each of two opposite sides of the seat or on extended tabs above the seat is a slanted wall or a slanted flange attached to a wall such that a distance between the two wails or flanges is greater as a distance away from the seat increases and lowest within the seat, and the walls or flanges converge to form a V-shape, such that the screw head is thereby configured to allow a malaligned or rotated rod or flexible connector or screw head to come together and slowly conform to one another as the rod or flexible connector is inserted into the seat of the screw head.
21. The apparatus of claim 2, comprising one or more ρair(s) of upwardly directed guide wires, wherein each pair of guide wires is connected to a pair of flexible strands that attach to a top of the downwardly directed screw shaft or the seat at a base of the screw head under where the rod or flexible connector is to sit, such that as the rod or flexible connector is lowered into the screw head, guided by the guide wires, the flexible strands are configured to wrap around the rod or flexible connector, each strand being just long enough (approximately half of a circumference of the rod or flexible connector) to wrap around the rod or flexible connector so that ends of the guide wires meet together above the rod or flexible connector and can be placed together and inserted within a cannulated locking assembly and/or other cannulated tools.
22. The apparatus of claims 2 or 21 , .wherein the upwardly directed guide wire and/or guide shaft is attached to the screw or screw head with a very thin material that is both flexible and can be tensed by pulling or tightening.
23. The apparatus of claim 22, wherein the material is in the form of a sheet that when tightened, guides the rod or flexible connector into the seat of the screw head.
47
24. The apparatus of claim 2, wherein the upwardly directed guide wire and/or guide shaft is attached to the screw or screw head through a mechanical clamp or device that securely holds the screw head, and the clamp/device is removed along with the wire after the rod or flexible connector is guided into place in the screw head and locked in place.
25. The apparatus of claim 2, wherein the upwardly directed guide wire and/or guide shaft is attached to the screw or screw head by a ring or loop that the downwardly directed screw shaft fits through but that the screw head cannot fit through.
26. The apparatus of claim 2, wherein the upwardly directed guide wire and/or guide shaft 1 is attached to one or a multitude of wires, threads, strands, or extensor tabs that are then attached to the screw or screw head.
27. The apparatus of claim 2, further comprising a shortened tower such as one that is conventionally used for placing screws, rods or flexible connectors, and locking assemblies in minimally invasive systems; wherein the shortened tower is attached to the screw or screw head at its base and attached to the upwardly directed guide wire and/or guide shaft at its top; and wherein the shortened tower is configured to function, at its base, as do standard towers conventionally used for minimally invasive pedicle screw systems, while also permitting insertion of multiple hybrid wire/tower constructs through a single small incision due to only a wire portion, at its top, extending though the incision at skin level to prevent overcrowding of towers at that level.
28. The apparatus of claim 2, further comprising at least one retention thread for each rod or flexible connector, arranged in one or more loop(s) along one or more side(s) of the rod or flexible connector to serve as a guide rail as the upwardly directed guide wire(s) and/or guide shaft(s) extending from the screw head pass through it; wherein the retention thread is attached to the rod or flexible connector at an end face of the rod or flexible connector or along a side of the rod or flexible connector a short
48 distance away from the end face, so as to ensure that the end of the rod or flexible connector fits completely through the screw head.
29. The apparatus of claim 28, wherein the retention thread is biodegradable and naturally disintegrates with time after the rod or flexible connector has been placed in the screw head and securely tightened therein.
30. The apparatus of claim 2, wherein at least one guide wire or guide shaft is coded to distinguish it from at least one other guide wire or guide shaft.
31. The apparatus of claim 2, wherein at least one guide wire or guide shaft is coded to group it with at least one other wire or guide shaft.
32. The apparatus of claim 2, wherein the upwardly directed guide wire(s) and/or guide shaft(s) have markers thereon to denote their depth of insertion beneath skin of a patient's body such that these depth markers can be used to reflect a virtual image of a contour of the screw heads so that the rod or flexible connector can be pre-bent accurately outside the body, and in this manner the guide wire(s) and/or guide shaft(s) act similarly to light rays that are focused into a single point by a convex lens which then creates a virtual mirror image at an equal distance from a focal point, the focal point in this case being a point at which the wires come closest together.
33. The apparatus of claim 2, wherein the rod or flexible connector element is a flexible connector to allow dynamic stabilization, permitting some motion, without complete fusion of the vertebrae.
34. The apparatus of claim 33, wherein the rod or flexible connector is made of a polymer material comprising polyetheretherketone (PEEK).
49
35. A method of using the apparatus of claim 2, wherein the rod or flexible connector is inserted through a first incision and tunneled through tissue to fit between upwardly directed guide wires and/or guide shafts attached to screws inserted through separate additional incisions.
36. The method of claim 35, wherein two or more upwardly directed guide wires and/or guide shafts on a screw or screw head are spread apart to widen a gap between them to allow easier capture of the rod or flexible connector, including when the rod or flexible connector does not have retention threads, including when the screws through which the rod or flexible connector is inserted were inserted through separate incisions from the rod or flexible connector.
37. A method of rosing together or dynamically stabilizing at least two vertebrae using the apparatus of claim 2, comprising:
(i) inserting a first screw into a first vertebra, wherein the first screw has a first screw head attached to a first group of one or more wire(s); (ii) inserting a second screw into a second vertebra, wherein the second screw has a second screw head;
(iii) inserting a rod or flexible connector; (iv) guiding the rod or flexible connector along the first group of wires to the first screw head of the first screw in the first vertebra; (v) guiding the rod or flexible connector to the second screw head of the second screw in the second vertebra; and (vi) disconnecting one or more wire(s) from one or more screw head(s).
38. The method of claim 37, wherein the second screw head is attached to a second group of one or more wire(s) and the rod or flexible connector is guided to the second screw head of the second screw through the second group of wires.
50
39. The method of claim 37, wherein the second screw is inserted through a conventional tower and the rod or flexible connector is also inserted through the tower and guided down to the second screw head of the second screw through the tower.
40. The method of claim 37, after the steps of guiding the rod or flexible connector and before the step of disconnecting the wires, further comprising steps of: guiding the locking assemblies along the wire(s) down to the screw heads over the rod or flexible connector or, when the locking assemblies are part of the screw heads, manipulating the locking assemblies with an instrument; and tightening the locking assemblies upon each screw head to secure a position of the rod or flexible connector.
41. The method of claim 37, further comprising steps of:
(i) removing a defective disk from an intervertebral body space via an opening at a foramina; and (ii) inserting a spacer therein.
42. The method of claim 41» further comprising one or more step of: decorticating a facet joint and bone around the screws and inserting bone graft material around the spacer, the rod or flexible connector(s), and the screws.
43. A method of guiding a rod or flexible connector, specially adapted to ruse or stabilize adjacent vertebrae, into a screw head using the apparatus of claim 1, comprising a step in which one or more guiding element(s) attached to the screw head open up to receive and direct the rod or flexible connector into the screw head.
44. The method of claim 43, wherein the rod or flexible connector is inserted through a different incision than the screw head.
51
45. The method of claim 43, wherein a T-shaped tool is inserted to open up the guiding element(s) to receive the rod or flexible connector.
46. The method of claim 45, wherein the T-shaped tool has a hinge such that it forms a straight shape during insertion and removal, with sides of the T-shapc parallel to a longitudinal axis and configured to turn perpendicular about the hinge after insertion and before removal to open up the guiding element(s).
\
47. The method of claim 45, wherein the T-shaped tool has two radially extending arms that expand radially outward in a direction perpendicular to a longitudinal insertion axis when a housing over them is retracted.
48. A method of guiding a rod or flexible connector adapted to fuse or stabilize adjacent vertebrae into a screw head using the apparatus as in claim 1 and further comprising one or more guiding element(s) attached to the screw head, and' a thread attached to an end face of the rod or flexible connector; comprising a step of using the thread to pull the rod or flexible connector through the guiding elements) attached to the screw head.
49. The apparatus of claim 2, wherein upwardly directed guide wire(s) and/or guide shaft(s) associated with each of 2 or more screws extend upward from their respective screw heads through one or more skin incision sites to form, as idealized lines or cylinders in space, a configuration selected from the group consisting of:
(i) parallel configuration of the guide wire(s) and/or guide shafts) associated with different screws; (ii) skew configuration where the guide wire(s) and/or guide shaft(s) associated with different screws are neither parallel or intersecting; (iii) converging but not intersecting configuration; (iv) intersecting at a "V'-configuration where the proximal ends intersect outside a surface of skin and at an angle between 0 and 180 degrees; (v) intersecting at a "T" configuration where a proximal end of the guide wire(s) and/or guide shaft(s) from one screw intersects the guide wire(s) and/or guide
52 shaft(s) from another screw(s) at a point other than at an end of the guidance elements) and at an angle between 0 and 180 degrees; (vi) intersecting at an "X"-configuration or a criss-cross configuration where guide wire(s) and/or guide shaft(s) of two or more screws intersect at points not at the ends of the guidance elements and at an angle between 0 and 180 degrees; and (vii) diverging configuration where the proximal ends outside the skin are farther apart than the distal ends at the screw head.
50. The apparatus of claim 49, wherein upwardly directed guide wire(s) and/or guide shaft(s) from two or more screws extend upward from their respective screw heads to form the '^"-configuration, the "X"-configuration comprising guide wire(s) and/or guide shaft(s) that intersect or criss-cross above, at, or below a surface of skin at one or more incision sites.
51. The apparatus of claim 49, wherein a lumen bounded by the upwardly directed guide wire(s) and/or guide shaft(s) for each screw passes through and intersects with one or more lumens associated with guidance elements for other screws such that each lumen participating in the intersection continues to be freely accessible by tools, rods, and locking assemblies without interference down to the screw head.
52. The apparatus of claim 2, wherein the upwardly directed guide wire(s) and/or guide shaft(s) for two or more screw heads are configured to pass through a common incision, wherein the common incision is smaller than the sum of the maximal widths of two respective largest elements for each screw that are inserted through the common .incision, where an element includes the screw, screw head, rod, locking assembly, and associated tools.
53. The apparatus of claim 1 , wherein the screw head is polyaxial.
53
PCT/US2009/059004 2008-10-01 2009-09-30 System and method for wire-guided pedicle screw stabilization of spinal vertebrae WO2010039817A2 (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
CN200980140693.1A CN102186433B (en) 2008-10-01 2009-09-30 System and method for wire-guided pedicle screw stabilization of spinal vertebrae
EP09818436.9A EP2341858B1 (en) 2008-10-01 2009-09-30 System for wire-guided pedicle screw stabilization of spinal vertebrae
CA2739431A CA2739431C (en) 2008-10-01 2009-09-30 System and method for wire-guided pedicle screw stabilization of spinal vertebrae
KR1020117009465A KR101679088B1 (en) 2008-10-01 2009-09-30 System and method for wire-guided pedicle screw stabilization of spinal vertebrae
JP2011530168A JP5795534B2 (en) 2008-10-01 2009-09-30 System and method for wire-guided pedicle screw stabilization of vertebrae
ES09818436.9T ES2462759T3 (en) 2008-10-01 2009-09-30 System for pedicle screw stabilization guided by column vertebrae wire
AU2009298554A AU2009298554B2 (en) 2008-10-01 2009-09-30 System and method for wire-guided pedicle screw stabilization of spinal vertebrae
US13/122,388 US8556940B2 (en) 2008-10-01 2009-09-30 System and method for wire-guided pedicle screw stabilization of spinal vertebrae
BRPI0920821A BRPI0920821B8 (en) 2008-10-01 2009-09-30 bone stabilization system and screw for use in bone stabilization
RU2011113701/14A RU2513155C2 (en) 2008-10-01 2009-09-30 System and method for spine stabilisation using wired pedicle screw
MX2011003046A MX345890B (en) 2008-10-01 2009-09-30 System and method for wire-guided pedicle screw stabilization of spinal vertebrae.
PCT/US2010/029199 WO2011040986A1 (en) 2009-09-30 2010-03-30 System and method for offset guidance in pedicle screw stabilization of spinal vertebrae
US13/082,346 US8721691B2 (en) 2008-10-01 2011-04-07 Systems and methods for pedicle screw stabilization of spinal vertebrae
US13/098,325 US8545541B2 (en) 2008-10-01 2011-04-29 System and method for wire-guided pedicle screw stabilization of spinal vertebrae
US13/189,432 US10973551B2 (en) 2008-10-01 2011-07-22 Systems and methods for pedicle screw stabilization of spinal vertebrae
US13/245,227 US8333770B2 (en) 2008-10-01 2011-09-26 Systems and methods for pedicle screw stabilization of spinal vertebrae
US13/246,432 US8216282B2 (en) 2008-10-01 2011-09-27 System and method for wire-guided pedicle screw stabilization of spinal vertebrae
AU2016201395A AU2016201395B2 (en) 2008-10-01 2016-03-03 System and method for wire-guided pedicle screw stabilization of spinal vertebrae
AU2017245407A AU2017245407B2 (en) 2008-10-01 2017-10-12 System and method for wire-guided pedicle screw stabilization of spinal vertebrae
AU2019210492A AU2019210492A1 (en) 2008-10-01 2019-07-29 System and method for wire-guided pedicle screw stabilization of spinal vertebrae
US17/025,815 US11759238B2 (en) 2008-10-01 2020-09-18 Systems and methods for pedicle screw stabilization of spinal vertebrae

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10193208P 2008-10-01 2008-10-01
US61/101,932 2008-10-01

Related Child Applications (5)

Application Number Title Priority Date Filing Date
US13/122,388 A-371-Of-International US8556940B2 (en) 2008-10-01 2009-09-30 System and method for wire-guided pedicle screw stabilization of spinal vertebrae
PCT/US2010/029199 Continuation-In-Part WO2011040986A1 (en) 2008-10-01 2010-03-30 System and method for offset guidance in pedicle screw stabilization of spinal vertebrae
US13/082,346 Continuation-In-Part US8721691B2 (en) 2008-10-01 2011-04-07 Systems and methods for pedicle screw stabilization of spinal vertebrae
US13/098,325 Continuation US8545541B2 (en) 2008-10-01 2011-04-29 System and method for wire-guided pedicle screw stabilization of spinal vertebrae
US13/246,432 Continuation US8216282B2 (en) 2008-10-01 2011-09-27 System and method for wire-guided pedicle screw stabilization of spinal vertebrae

Publications (3)

Publication Number Publication Date
WO2010039817A2 WO2010039817A2 (en) 2010-04-08
WO2010039817A3 WO2010039817A3 (en) 2010-07-22
WO2010039817A4 true WO2010039817A4 (en) 2010-09-16

Family

ID=42074180

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/059004 WO2010039817A2 (en) 2008-10-01 2009-09-30 System and method for wire-guided pedicle screw stabilization of spinal vertebrae

Country Status (12)

Country Link
US (5) US8556940B2 (en)
EP (1) EP2341858B1 (en)
JP (1) JP5795534B2 (en)
KR (1) KR101679088B1 (en)
CN (1) CN102186433B (en)
AU (4) AU2009298554B2 (en)
BR (1) BRPI0920821B8 (en)
CA (1) CA2739431C (en)
ES (1) ES2462759T3 (en)
MX (1) MX345890B (en)
RU (1) RU2513155C2 (en)
WO (1) WO2010039817A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8216282B2 (en) 2008-10-01 2012-07-10 Sherwin Hua System and method for wire-guided pedicle screw stabilization of spinal vertebrae
US8333770B2 (en) 2008-10-01 2012-12-18 Sherwin Hua Systems and methods for pedicle screw stabilization of spinal vertebrae

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9155544B2 (en) * 2002-03-20 2015-10-13 P Tech, Llc Robotic systems and methods
US8549888B2 (en) 2008-04-04 2013-10-08 Nuvasive, Inc. System and device for designing and forming a surgical implant
US8388659B1 (en) 2008-10-17 2013-03-05 Theken Spine, Llc Spondylolisthesis screw and instrument for implantation
US9655658B2 (en) * 2009-10-14 2017-05-23 Ebi, Llc Deformable device for minimally invasive fixation
US8236032B2 (en) * 2009-10-20 2012-08-07 Depuy Spine, Inc. Spinal implant with a flexible extension element
AU2011232543B2 (en) 2010-03-26 2015-11-19 Echostar Technologies L.L.C. Multiple input television receiver
US8337530B2 (en) * 2011-03-09 2012-12-25 Zimmer Spine, Inc. Polyaxial pedicle screw with increased angulation
FR2977471B1 (en) * 2011-07-07 2013-07-05 Aspide Medical DEVICE COMPRISING A PLURALITY OF IMPLANTS FOR FIXING PROTHETIC EQUIPMENT
US8657855B2 (en) * 2011-10-17 2014-02-25 Warsaw Orthopedic, Inc. Spinal fixation implant for mounting to spinous processes and related method
US9289250B2 (en) * 2011-10-17 2016-03-22 Warsaw Orthopedic, Inc. Extender collar system
RU2472461C1 (en) * 2011-11-23 2013-01-20 Государственное учреждение здравоохранения "Свердловская областная клиническая больница №1" Method of anterior spondylodesis in case of non-specific spine spondylodiscitis (versions)
US11207132B2 (en) 2012-03-12 2021-12-28 Nuvasive, Inc. Systems and methods for performing spinal surgery
US20150282847A1 (en) * 2012-10-23 2015-10-08 Charles R. Gordon Method of Positioning Pedicle Screws and Spinal Rods and Apparatuses for the Same
US9486256B1 (en) 2013-03-15 2016-11-08 Nuvasive, Inc. Rod reduction assemblies and related methods
US10136927B1 (en) 2013-03-15 2018-11-27 Nuvasive, Inc. Rod reduction assemblies and related methods
US10786283B2 (en) * 2013-08-01 2020-09-29 Musc Foundation For Research Development Skeletal bone fixation mechanism
US9848922B2 (en) 2013-10-09 2017-12-26 Nuvasive, Inc. Systems and methods for performing spine surgery
WO2015116624A1 (en) * 2014-01-29 2015-08-06 Spinal Usa, Inc. Minimally invasive devices, systems and methods for treating the spine
EP3148457A4 (en) * 2014-05-27 2018-06-06 Interventional Spine, Inc. Method and apparatus for spondylolysis repair
US9730684B2 (en) * 2014-07-07 2017-08-15 Warsaw Orthopedic, Inc. Multiple spinal surgical pathways systems and methods
US9913669B1 (en) 2014-10-17 2018-03-13 Nuvasive, Inc. Systems and methods for performing spine surgery
CN105989769B (en) * 2015-02-02 2019-03-19 中国科学院沈阳自动化研究所 A kind of minimally invasive spine surgical simulation force feedback surgery training device and method
US20150216540A1 (en) * 2015-04-13 2015-08-06 Ashkan Khajoo Trans pars interarticularis operation for releasing of the adhesions in lumbar spinal reoperations
US10149710B2 (en) 2015-05-11 2018-12-11 Providence Medical Technology, Inc. Bone screw and implant delivery device
JP6831798B2 (en) 2015-05-11 2021-02-17 プロビデンス メディカル テクノロジー インコーポレイテッド Bone screw and implant delivery device
WO2017125837A2 (en) * 2016-01-18 2017-07-27 Premia Spine Ltd. Fusion rod insertion in percutaneous fusion surgery
US10368881B2 (en) 2016-06-03 2019-08-06 Quandary Medical, Llc Method and apparatus for minimally invasive posterolateral spinal fusion
US10564380B2 (en) * 2016-07-05 2020-02-18 Raytheon Company Positional alignment mechanism for a lens assembly
EP3503827A4 (en) 2016-08-24 2020-08-05 Integrity Implants Inc. Adjustable bone fixation systems
TWI637721B (en) * 2016-09-12 2018-10-11 台灣微創醫療器材股份有限公司 Spinal surgical tool
WO2018058102A1 (en) 2016-09-26 2018-03-29 Dr. Bryan Barnes Pc. Apparatus, system, and method for spinal vertebrae stabilization
US10779866B2 (en) 2016-12-29 2020-09-22 K2M, Inc. Rod reducer assembly
RU2677616C2 (en) * 2017-06-19 2019-01-17 Государственное Бюджетное Учреждение Санкт-Петербургский Научно-Исследовательский Институт Скорой Помощи Им. И.И. Джанелидзе" Method of osteosynthesis of pelvic fractures
US20200360059A1 (en) * 2018-01-30 2020-11-19 Orthopediatrics Corp. Segmental tensioning of spinal tethers
RU2678467C1 (en) * 2018-02-02 2019-01-29 Государственное бюджетное учреждение здравоохранения города Москвы Научно-исследовательский институт скорой помощи имени Н.В. Склифосовского Департамента здравоохранения г. Москвы Method of conducting transpedicular fixation of lower cervical spine
US11051861B2 (en) 2018-06-13 2021-07-06 Nuvasive, Inc. Rod reduction assemblies and related methods
US11160580B2 (en) 2019-04-24 2021-11-02 Spine23 Inc. Systems and methods for pedicle screw stabilization of spinal vertebrae
RU2726399C1 (en) * 2020-01-14 2020-07-13 федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр травматологии и ортопедии имени академика Г.А. Илизарова" Министерства здравоохранения Российской Федерации Method of posterior-transforaminal interbody spinal fusion accompanied by decompressor-stabilizing operations on lumbar spine
RU2759406C1 (en) * 2020-03-05 2021-11-12 Игорь Викторович Балязин-Парфенов Device for percutaneous removal of herniated intervertebral discs of the cervical spine with endoscopic assistance
KR102208305B1 (en) * 2020-06-17 2021-01-27 주식회사 텍코드 Interbody Fusion cage operation system
RU2756428C1 (en) * 2020-12-09 2021-09-30 Александр Иванович Колесник Device for open reposition of displaced columns of acetabulum

Family Cites Families (333)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4448191A (en) 1981-07-07 1984-05-15 Rodnyansky Lazar I Implantable correctant of a spinal curvature and a method for treatment of a spinal curvature
CA1333209C (en) 1988-06-28 1994-11-29 Gary Karlin Michelson Artificial spinal fusion implants
FR2642645B1 (en) 1989-02-03 1992-08-14 Breard Francis FLEXIBLE INTERVERTEBRAL STABILIZER AND METHOD AND APPARATUS FOR CONTROLLING ITS VOLTAGE BEFORE PLACEMENT ON THE RACHIS
RU1771717C (en) 1989-10-30 1992-10-30 В.Г.Елизаров, О.Р.Герасимов и И.В.Буслов Device for spinal column stabilization
US5242443A (en) 1991-08-15 1993-09-07 Smith & Nephew Dyonics, Inc. Percutaneous fixation of vertebrae
FR2682281B1 (en) 1991-10-11 1997-01-03 Sofamor PERCUTANEOUS SCREW, INTENDED TO SUPPORT IN PARTICULAR A STEREOTAXY FRAMEWORK
US5193539A (en) 1991-12-18 1993-03-16 Alfred E. Mann Foundation For Scientific Research Implantable microstimulator
US5171279A (en) 1992-03-17 1992-12-15 Danek Medical Method for subcutaneous suprafascial pedicular internal fixation
DE69315704T3 (en) 1992-10-01 2002-08-01 Cardiac Pacemakers Inc STENT-LIKE STRUCTURE FOR DEFLICTION ELECTRODES
SE9203733D0 (en) 1992-12-11 1992-12-11 Siemens Elema Ab defibrillation
US5306275A (en) 1992-12-31 1994-04-26 Bryan Donald W Lumbar spine fixation apparatus and method
FR2709246B1 (en) 1993-08-27 1995-09-29 Martin Jean Raymond Dynamic implanted spinal orthosis.
US5688272A (en) 1995-03-30 1997-11-18 Danek Medical, Inc. Top-tightening transverse connector for a spinal fixation system
US6051017A (en) 1996-02-20 2000-04-18 Advanced Bionics Corporation Implantable microstimulator and systems employing the same
US5865842A (en) 1996-08-29 1999-02-02 Medtronic, Inc. System and method for anchoring brain stimulation lead or catheter
JP2871621B2 (en) 1996-09-06 1999-03-17 株式会社ロバート・リード商会 Head support device
FR2757761B1 (en) * 1996-12-27 1999-08-20 Stryker France Sa SPINE OTEOSYNTHESIS SYSTEM WITH POSITION ADJUSTMENT
ATE455509T1 (en) 1997-02-11 2010-02-15 Zimmer Spine Inc PLATE FOR THE FRONT CERVICAL SPINE WITH FIXATION SYSTEM FOR SCREWS
EP1011792B1 (en) 1997-02-26 2005-12-07 Alfred E. Mann Foundation for Scientific Research Battery-powered patient implantable device
US6208894B1 (en) 1997-02-26 2001-03-27 Alfred E. Mann Foundation For Scientific Research And Advanced Bionics System of implantable devices for monitoring and/or affecting body parameters
US7107103B2 (en) 1997-02-26 2006-09-12 Alfred E. Mann Foundation For Scientific Research Full-body charger for battery-powered patient implantable device
US6862465B2 (en) 1997-03-04 2005-03-01 Dexcom, Inc. Device and method for determining analyte levels
US5975085A (en) 1997-05-01 1999-11-02 Medtronic, Inc. Method of treating schizophrenia by brain stimulation and drug infusion
US6128537A (en) 1997-05-01 2000-10-03 Medtronic, Inc Techniques for treating anxiety by brain stimulation and drug infusion
DE19726141A1 (en) 1997-06-19 1999-01-28 Daum Gmbh Device for inserting medical instrument into neuronal part of head
US6731976B2 (en) 1997-09-03 2004-05-04 Medtronic, Inc. Device and method to measure and communicate body parameters
GB2330078A (en) 1997-10-08 1999-04-14 David Brian Ashton Hutchinson Bolt for facilitating catheter insertion
US6427086B1 (en) 1997-10-27 2002-07-30 Neuropace, Inc. Means and method for the intracranial placement of a neurostimulator
US6597954B1 (en) 1997-10-27 2003-07-22 Neuropace, Inc. System and method for controlling epileptic seizures with spatially separated detection and stimulation electrodes
US6016449A (en) 1997-10-27 2000-01-18 Neuropace, Inc. System for treatment of neurological disorders
US6227203B1 (en) 1998-02-12 2001-05-08 Medtronic, Inc. Techniques for controlling abnormal involuntary movements by brain stimulation and drug infusion
US6546277B1 (en) 1998-04-21 2003-04-08 Neutar L.L.C. Instrument guidance system for spinal and other surgery
US6161047A (en) 1998-04-30 2000-12-12 Medtronic Inc. Apparatus and method for expanding a stimulation lead body in situ
US6319241B1 (en) 1998-04-30 2001-11-20 Medtronic, Inc. Techniques for positioning therapy delivery elements within a spinal cord or a brain
US5938689A (en) 1998-05-01 1999-08-17 Neuropace, Inc. Electrode configuration for a brain neuropacemaker
US6711430B1 (en) 1998-10-09 2004-03-23 Insight Neuroimaging Systems, Inc. Method and apparatus for performing neuroimaging
US7277758B2 (en) 1998-08-05 2007-10-02 Neurovista Corporation Methods and systems for predicting future symptomatology in a patient suffering from a neurological or psychiatric disorder
US7209787B2 (en) 1998-08-05 2007-04-24 Bioneuronics Corporation Apparatus and method for closed-loop intracranial stimulation for optimal control of neurological disease
US7974696B1 (en) 1998-08-05 2011-07-05 Dilorenzo Biomedical, Llc Closed-loop autonomic neuromodulation for optimal control of neurological and metabolic disease
US6366813B1 (en) 1998-08-05 2002-04-02 Dilorenzo Daniel J. Apparatus and method for closed-loop intracranical stimulation for optimal control of neurological disease
US6240316B1 (en) 1998-08-14 2001-05-29 Advanced Bionics Corporation Implantable microstimulation system for treatment of sleep apnea
US6482182B1 (en) 1998-09-03 2002-11-19 Surgical Navigation Technologies, Inc. Anchoring system for a brain lead
GB9821575D0 (en) 1998-10-02 1998-11-25 Diametrics Medical Limited Cranial bolt
US6208881B1 (en) 1998-10-20 2001-03-27 Micropure Medical, Inc. Catheter with thin film electrodes and method for making same
US6011991A (en) 1998-12-07 2000-01-04 Technology Patents, Llc Communication system and method including brain wave analysis and/or use of brain activity
US6214016B1 (en) 1999-04-29 2001-04-10 Medtronic, Inc. Medical instrument positioning device internal to a catheter or lead and method of use
US6176242B1 (en) 1999-04-30 2001-01-23 Medtronic Inc Method of treating manic depression by brain infusion
US6343226B1 (en) 1999-06-25 2002-01-29 Neurokinetic Aps Multifunction electrode for neural tissue stimulation
DE69923299T2 (en) 1999-06-25 2006-01-05 Neurokinetic Aps Multifunctional electrode for the stimulation of neuronal tissues
US6530929B1 (en) 1999-10-20 2003-03-11 Sdgi Holdings, Inc. Instruments for stabilization of bony structures
US6764498B2 (en) 1999-12-09 2004-07-20 Hans Alois Mische Methods and devices for treatment of neurological disorders
US7300449B2 (en) 1999-12-09 2007-11-27 Mische Hans A Methods and devices for the treatment of neurological and physiological disorders
AU3441001A (en) 1999-12-01 2001-06-12 Advanced Cardiovascular Systems Inc. Nitinol alloy design and composition for vascular stents
GB9928248D0 (en) 1999-12-01 2000-01-26 Gill Steven S An implantable guide tube for neurosurgery
US6549810B1 (en) 1999-12-01 2003-04-15 Vertis Neuroscience, Inc. Percutaneous electrical therapy system with electrode depth control
US6622051B1 (en) 1999-12-01 2003-09-16 Vertis Neuroscience, Inc. Percutaneous electrical therapy system with electrode entry angle control
US6493592B1 (en) 1999-12-01 2002-12-10 Vertis Neuroscience, Inc. Percutaneous electrical therapy system with electrode position maintenance
AU782860B2 (en) 1999-12-07 2005-09-01 Krasnow Institute Adaptive electric field modulation of neural systems
US6235028B1 (en) 2000-02-14 2001-05-22 Sdgi Holdings, Inc. Surgical guide rod
US6582441B1 (en) 2000-02-24 2003-06-24 Advanced Bionics Corporation Surgical insertion tool
AU2001268473A1 (en) 2000-06-20 2002-01-02 Advanced Bionics Corporation Apparatus for treatment of mood and/or anxiety disorders by electrical brain stimulation and/or drug infusion
US6821277B2 (en) * 2000-06-23 2004-11-23 University Of Southern California Patent And Copyright Administration Percutaneous vertebral fusion system
US7305268B2 (en) 2000-07-13 2007-12-04 Northstar Neurscience, Inc. Systems and methods for automatically optimizing stimulus parameters and electrode configurations for neuro-stimulators
US7146217B2 (en) 2000-07-13 2006-12-05 Northstar Neuroscience, Inc. Methods and apparatus for effectuating a change in a neural-function of a patient
US7672730B2 (en) 2001-03-08 2010-03-02 Advanced Neuromodulation Systems, Inc. Methods and apparatus for effectuating a lasting change in a neural-function of a patient
US7236831B2 (en) 2000-07-13 2007-06-26 Northstar Neuroscience, Inc. Methods and apparatus for effectuating a lasting change in a neural-function of a patient
US6862479B1 (en) 2000-08-30 2005-03-01 Advanced Bionics Corporation Spinal cord stimulation as a therapy for sexual dysfunction
US6591138B1 (en) 2000-08-31 2003-07-08 Neuropace, Inc. Low frequency neurostimulator for the treatment of neurological disorders
US6485491B1 (en) 2000-09-15 2002-11-26 Sdgi Holdings, Inc. Posterior fixation system
US6871098B2 (en) 2000-10-30 2005-03-22 Medtronic, Inc. Method for treating obsessive-compulsive disorder with electrical stimulation of the brain internal capsule
US7493171B1 (en) 2000-11-21 2009-02-17 Boston Scientific Neuromodulation Corp. Treatment of pathologic craving and aversion syndromes and eating disorders by electrical brain stimulation and/or drug infusion
US6950707B2 (en) 2000-11-21 2005-09-27 Advanced Bionics Corporation Systems and methods for treatment of obesity and eating disorders by electrical brain stimulation and/or drug infusion
US6922590B1 (en) 2000-11-21 2005-07-26 Advanced Bionics Corporation Systems and methods for treatment of diabetes by electrical brain stimulation and/or drug infusion
US7440806B1 (en) 2000-11-21 2008-10-21 Boston Scientific Neuromodulation Corp. Systems and methods for treatment of diabetes by electrical brain stimulation and/or drug infusion
WO2002062215A2 (en) 2001-01-04 2002-08-15 Medtronic, Inc. Implantable medical device with sensor
US6445953B1 (en) 2001-01-16 2002-09-03 Kenergy, Inc. Wireless cardiac pacing system with vascular electrode-stents
US6929606B2 (en) 2001-01-29 2005-08-16 Depuy Spine, Inc. Retractor and method for spinal pedicle screw placement
US6788975B1 (en) 2001-01-30 2004-09-07 Advanced Bionics Corporation Fully implantable miniature neurostimulator for stimulation as a therapy for epilepsy
US6735475B1 (en) 2001-01-30 2004-05-11 Advanced Bionics Corporation Fully implantable miniature neurostimulator for stimulation as a therapy for headache and/or facial pain
US7167751B1 (en) 2001-03-01 2007-01-23 Advanced Bionics Corporation Method of using a fully implantable miniature neurostimulator for vagus nerve stimulation
US7299096B2 (en) 2001-03-08 2007-11-20 Northstar Neuroscience, Inc. System and method for treating Parkinson's Disease and other movement disorders
EP1370205B1 (en) 2001-03-19 2013-08-14 Cochlear Limited Insertion tool system for an electrode array
US7862587B2 (en) 2004-02-27 2011-01-04 Jackson Roger P Dynamic stabilization assemblies, tool set and method
EP1269913B1 (en) 2001-06-28 2004-08-04 BrainLAB AG Device for transcranial magnetic stimulation and cortical cartography
US7013177B1 (en) 2001-07-05 2006-03-14 Advanced Bionics Corporation Treatment of pain by brain stimulation
JP2004534595A (en) 2001-07-12 2004-11-18 ヒル−ロム サービシズ，インコーポレイテッド Control of vacuum rate of change
US7150737B2 (en) 2001-07-13 2006-12-19 Sci/Med Life Systems, Inc. Methods and apparatuses for navigating the subarachnoid space
US20060241717A1 (en) 2001-08-30 2006-10-26 Whitehurst Todd K Treatment of movement disorders by extra dural motor cortex stimulation
US6970741B1 (en) 2001-09-18 2005-11-29 Advanced Bionics Corporation Monitoring, preventing, and treating rejection of transplanted organs
EP1441679B8 (en) 2001-10-24 2018-05-30 MED-EL Elektromedizinische Geräte GmbH Implantable fluid delivery apparatuses and implantable electrode
US7209788B2 (en) 2001-10-29 2007-04-24 Duke University Closed loop brain machine interface
US7824410B2 (en) 2001-10-30 2010-11-02 Depuy Spine, Inc. Instruments and methods for minimally invasive spine surgery
US20030088245A1 (en) 2001-11-02 2003-05-08 Arthrocare Corporation Methods and apparatus for electrosurgical ventriculostomy
US7037288B2 (en) 2002-01-14 2006-05-02 Codman & Shurtleff, Inc. Anti-block catheter
WO2003066153A2 (en) 2002-02-01 2003-08-14 The Cleveland Clinic Foundation Neural stimulation delivery device with independently moveable delivery structures
US6669729B2 (en) 2002-03-08 2003-12-30 Kingsley Richard Chin Apparatus and method for the replacement of posterior vertebral elements
US7221981B2 (en) 2002-03-28 2007-05-22 Northstar Neuroscience, Inc. Electrode geometries for efficient neural stimulation
US20030199961A1 (en) 2002-04-03 2003-10-23 Bjorklund Vicki L. Method and apparatus for fixating a pacing lead of an implantable medical device
US7572276B2 (en) 2002-05-06 2009-08-11 Warsaw Orthopedic, Inc. Minimally invasive instruments and methods for inserting implants
US7003352B1 (en) 2002-05-24 2006-02-21 Advanced Bionics Corporation Treatment of epilepsy by brain stimulation
US20050182453A1 (en) 2002-05-24 2005-08-18 Whitehurst Todd K. Treatment of epilepsy by high frequency electrical stimulation and/or drug stimulation
US7151961B1 (en) 2002-05-24 2006-12-19 Advanced Bionics Corporation Treatment of movement disorders by brain stimulation
US20030233126A1 (en) 2002-06-12 2003-12-18 Alfred E. Mann Institute For Biomedical Engineering Injection devices and methods for testing implants
US20070265582A1 (en) 2002-06-12 2007-11-15 University Of Southern California Injection Devices for Unimpeded Target Location Testing
US7203548B2 (en) 2002-06-20 2007-04-10 Advanced Bionics Corporation Cavernous nerve stimulation via unidirectional propagation of action potentials
US7292890B2 (en) 2002-06-20 2007-11-06 Advanced Bionics Corporation Vagus nerve stimulation via unidirectional propagation of action potentials
CA2762938C (en) 2002-06-28 2015-05-05 Boston Scientific Neuromodulation Corporation Microstimulator having self-contained power source and bi-directional telemetry system
US7006859B1 (en) 2002-07-20 2006-02-28 Flint Hills Scientific, L.L.C. Unitized electrode with three-dimensional multi-site, multi-modal capabilities for detection and control of brain state changes
US7787934B2 (en) 2002-07-29 2010-08-31 Medtronic, Inc. Fiducial marker devices, tools, and methods
US7306603B2 (en) 2002-08-21 2007-12-11 Innovative Spinal Technologies Device and method for percutaneous placement of lumbar pedicle screws and connecting rods
US7615070B2 (en) 2002-10-11 2009-11-10 Spineco, Inc. Electro-stimulation and medical delivery device
US7063725B2 (en) 2002-10-21 2006-06-20 Sdgi Holdings, Inc. Systems and techniques for restoring and maintaining intervertebral anatomy
US20050049649A1 (en) 2002-10-21 2005-03-03 The Cleveland Clinic Foundation Electrical stimulation of the brain
US9539012B2 (en) 2002-10-30 2017-01-10 Zimmer Spine, Inc. Spinal stabilization systems with quick-connect sleeve assemblies for use in surgical procedures
US20040147928A1 (en) 2002-10-30 2004-07-29 Landry Michael E. Spinal stabilization system using flexible members
CA2502571C (en) * 2002-10-30 2011-10-18 Spinal Concepts, Inc. Spinal stabilization system insertion and methods
US20060095035A1 (en) 2004-11-03 2006-05-04 Jones Robert J Instruments and methods for reduction of vertebral bodies
US7236830B2 (en) 2002-12-10 2007-06-26 Northstar Neuroscience, Inc. Systems and methods for enhancing or optimizing neural stimulation therapy for treating symptoms of Parkinson's disease and/or other movement disorders
US7302298B2 (en) 2002-11-27 2007-11-27 Northstar Neuroscience, Inc Methods and systems employing intracranial electrodes for neurostimulation and/or electroencephalography
US20050075680A1 (en) 2003-04-18 2005-04-07 Lowry David Warren Methods and systems for intracranial neurostimulation and/or sensing
US6959215B2 (en) 2002-12-09 2005-10-25 Northstar Neuroscience, Inc. Methods for treating essential tremor
AU2004204674A1 (en) 2003-01-03 2004-07-29 Advanced Neuromodulation Systems, Inc. System and method for stimulation of a person's brain stem
US7282064B2 (en) 2003-02-11 2007-10-16 Spinefrontier Lls Apparatus and method for connecting spinal vertebrae
CA2516388A1 (en) 2003-02-25 2004-09-10 Image-Guided Neurologics, Inc. Fiducial marker devices, tools, and methods
US7158333B1 (en) 2003-04-03 2007-01-02 Marvell International Ltd. Up-sampled filtering for servo demodulation
AU2003901696A0 (en) 2003-04-09 2003-05-01 Cochlear Limited Implant magnet system
US6990377B2 (en) 2003-04-24 2006-01-24 Northstar Neuroscience, Inc. Systems and methods for facilitating and/or effectuating development, rehabilitation, restoration, and/or recovery of visual function through neural stimulation
US7241283B2 (en) 2003-04-25 2007-07-10 Ad-Tech Medical Instrument Corp. Method for intracranial catheter treatment of brain tissue
US7473267B2 (en) 2003-04-25 2009-01-06 Warsaw Orthopedic, Inc. System and method for minimally invasive posterior fixation
US20040225335A1 (en) 2003-05-08 2004-11-11 Whitehurst Todd K. Treatment of Huntington's disease by brain stimulation
WO2005000090A2 (en) 2003-05-30 2005-01-06 Medi-Screw, Inc. Medical implant systems
US7468064B2 (en) 2003-08-21 2008-12-23 Warsaw Orthopedic, Inc. Systems and methods for positioning implants relative to bone anchors in surgical approaches to the spine
US7691120B2 (en) 2003-08-26 2010-04-06 Zimmer Spine, Inc. Access systems and methods for minimally invasive surgery
US7753901B2 (en) 2004-07-21 2010-07-13 Tyco Healthcare Group Lp Laparoscopic instrument and cannula assembly and related surgical method
US7955355B2 (en) 2003-09-24 2011-06-07 Stryker Spine Methods and devices for improving percutaneous access in minimally invasive surgeries
US7875031B2 (en) * 2003-09-24 2011-01-25 Spinefrontier, LLS System and method for implanting spinal stabilization devices
US20050203513A1 (en) 2003-09-24 2005-09-15 Tae-Ahn Jahng Spinal stabilization device
US8002798B2 (en) 2003-09-24 2011-08-23 Stryker Spine System and method for spinal implant placement
US20050102006A1 (en) 2003-09-25 2005-05-12 Whitehurst Todd K. Skull-mounted electrical stimulation system
US7187967B2 (en) 2003-09-30 2007-03-06 Neural Signals, Inc. Apparatus and method for detecting neural signals and using neural signals to drive external functions
US20070282395A1 (en) 2003-10-06 2007-12-06 Maltan Albert A System and method for preserving neuronal survival and plasticity of the auditory system prior to permanent intra-cochlear implantation
US20070282396A1 (en) 2003-10-14 2007-12-06 Overstreet Edward H System and method of contra-lateral ear stimulation for preserving neuronal survival and plasticity of the auditory system prior to permanent intra-cochlear implantation
US7588575B2 (en) 2003-10-21 2009-09-15 Innovative Spinal Technologies Extension for use with stabilization systems for internal structures
US7588588B2 (en) 2003-10-21 2009-09-15 Innovative Spinal Technologies System and method for stabilizing of internal structures
WO2005041863A2 (en) 2003-10-21 2005-05-12 Endius Incorporated Method for interconnecting longitudinal members extending along a spinal column
US9055934B2 (en) 2004-08-26 2015-06-16 Zimmer Spine, Inc. Methods and apparatus for access to and/or treatment of the spine
US7708764B2 (en) 2003-11-10 2010-05-04 Simonson Peter M Method for creating an artificial facet
US7174212B1 (en) 2003-12-10 2007-02-06 Pacesetter, Inc. Implantable medical device having a casing providing high-speed telemetry
US7120486B2 (en) 2003-12-12 2006-10-10 Washington University Brain computer interface
US7527638B2 (en) 2003-12-16 2009-05-05 Depuy Spine, Inc. Methods and devices for minimally invasive spinal fixation element placement
US7179261B2 (en) 2003-12-16 2007-02-20 Depuy Spine, Inc. Percutaneous access devices and bone anchor assemblies
US7666188B2 (en) 2003-12-16 2010-02-23 Depuy Spine, Inc. Methods and devices for spinal fixation element placement
US20050137652A1 (en) 2003-12-19 2005-06-23 The Board of Regents of the University of Texas at Dallas System and method for interfacing cellular matter with a machine
US8060207B2 (en) 2003-12-22 2011-11-15 Boston Scientific Scimed, Inc. Method of intravascularly delivering stimulation leads into direct contact with tissue
US20050137646A1 (en) 2003-12-22 2005-06-23 Scimed Life Systems, Inc. Method of intravascularly delivering stimulation leads into brain
US7647097B2 (en) 2003-12-29 2010-01-12 Braingate Co., Llc Transcutaneous implant
US7597694B2 (en) 2004-01-30 2009-10-06 Warsaw Orthopedic, Inc. Instruments and methods for minimally invasive spinal stabilization
WO2005076868A2 (en) 2004-02-06 2005-08-25 Depuy Spine, Inc. Devices and methods for inserting a spinal fixation element
US7295875B2 (en) 2004-02-20 2007-11-13 Boston Scientific Scimed, Inc. Method of stimulating/sensing brain with combination of intravascularly and non-vascularly delivered leads
US7160300B2 (en) * 2004-02-27 2007-01-09 Jackson Roger P Orthopedic implant rod reduction tool set and method
US7406105B2 (en) 2004-03-03 2008-07-29 Alfred E. Mann Foundation For Scientific Research System and method for sharing a common communication channel between multiple systems of implantable medical devices
US7590454B2 (en) 2004-03-12 2009-09-15 Boston Scientific Neuromodulation Corporation Modular stimulation lead network
US7547318B2 (en) 2004-03-19 2009-06-16 Depuy Spine, Inc. Spinal fixation element and methods
US7283856B2 (en) 2004-04-09 2007-10-16 Neuro Pace, Inc. Implantable lead system with seed electrodes
US7555347B2 (en) 2004-04-09 2009-06-30 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California Identification of target site for implantation of a microstimulator
US20050228380A1 (en) 2004-04-09 2005-10-13 Depuy Spine Inc. Instruments and methods for minimally invasive spine surgery
US7776051B2 (en) 2004-05-03 2010-08-17 Theken Spine, Llc System and method for displacement of bony structures
US7725196B2 (en) 2004-05-04 2010-05-25 The Cleveland Clinic Foundation Corpus callosum neuromodulation assembly
US7604658B2 (en) 2004-05-04 2009-10-20 Codman & Shurtleff, Inc. Multiple lumen sensor attachment
WO2005110529A1 (en) 2004-05-10 2005-11-24 Advanced Bionics Corporation Implantable electrode, insertion tool for use therewith, and insertion method
US8361165B2 (en) 2004-06-28 2013-01-29 Alfred E. Mann Foundation For Scientific Research Neural prosthetic with touch-like sensing
US7686814B2 (en) 2004-07-06 2010-03-30 Warsaw Orthopedic, Inc. Systems and methods for compressing and distracting vertebrae of the spinal column
US8209027B2 (en) 2004-07-07 2012-06-26 The Cleveland Clinic Foundation System and method to design structure for delivering electrical energy to tissue
US7286879B2 (en) 2004-07-16 2007-10-23 Boston Scientific Scimed, Inc. Method of stimulating fastigium nucleus to treat neurological disorders
WO2006015087A2 (en) 2004-07-27 2006-02-09 The Cleveland Clinic Foundation Thalamic stimulation device
US20060030872A1 (en) 2004-08-03 2006-02-09 Brad Culbert Dilation introducer for orthopedic surgery
US7465306B2 (en) 2004-08-13 2008-12-16 Warsaw Orthopedic, Inc. System and method for positioning a connecting member adjacent the spinal column in minimally invasive procedures
US20060058854A1 (en) 2004-09-14 2006-03-16 Scimed Life Systems, Inc. Method for stimulating neural tissue in response to a sensed physiological event
US20070265683A1 (en) 2004-09-24 2007-11-15 Dov Ehrlich Method and Apparatus for Treatment of Tinnitus and Other Neurological Disorders by Brain Stimulation in the Inferior Colliculi and/or In Adjacent Areas
US7666189B2 (en) 2004-09-29 2010-02-23 Synthes Usa, Llc Less invasive surgical system and methods
US20070239159A1 (en) 2005-07-22 2007-10-11 Vertiflex, Inc. Systems and methods for stabilization of bone structures
EP1814473B1 (en) 2004-10-25 2012-12-05 X-spine Systems, Inc. Pedicle screw systems
WO2006047652A2 (en) 2004-10-26 2006-05-04 Concept Matrix, Llc Working channel for minimally invasive spine surgery
RU2285483C2 (en) * 2004-11-25 2006-10-20 Общество с ограниченной ответственностью "КОНМЕТ" (ООО "КОНМЕТ") Device for performing stabilizing operation on spinal column (versions) and method of performing of stabilizing operation on spinal column
US7937160B2 (en) 2004-12-10 2011-05-03 Boston Scientific Neuromodulation Corporation Methods for delivering cortical electrode leads into patient's head
US8000795B2 (en) 2004-12-17 2011-08-16 Lozano Andres M Cognitive function within a human brain
US9327069B2 (en) 2004-12-21 2016-05-03 Boston Scientific Neuromodulation Corporation Methods and systems for treating a medical condition by promoting neural remodeling within the brain
US8515541B1 (en) 2004-12-22 2013-08-20 Boston Scientific Neuromodulation Corporation Methods and systems for treating post-stroke disorders
US9352145B2 (en) 2004-12-22 2016-05-31 Boston Scientific Neuromodulation Corporation Methods and systems for treating a psychotic disorder
US7386350B2 (en) 2005-01-11 2008-06-10 Vilims Bradley D Combination electrical stimulating and infusion medical device
US20060173522A1 (en) 2005-01-31 2006-08-03 Medtronic, Inc. Anchoring of a medical device component adjacent a dura of the brain or spinal cord
US7657316B2 (en) 2005-02-25 2010-02-02 Boston Scientific Neuromodulation Corporation Methods and systems for stimulating a motor cortex of the brain to treat a medical condition
US20060212090A1 (en) 2005-03-01 2006-09-21 Functional Neuroscience Inc. Method of treating cognitive disorders using neuromodulation
WO2006094015A2 (en) 2005-03-01 2006-09-08 Functional Neuroscience Inc. Method of treating depression, mood disorders and anxiety disorders using neuromodulation
US20060206165A1 (en) 2005-03-14 2006-09-14 Jaax Kristen N Occipital nerve stimulation to treat headaches and other conditions
CA2602292A1 (en) 2005-03-15 2006-09-21 The Regents Of The University Of California Method and system for modulating energy expenditure and neurotrophic factors
US7627383B2 (en) 2005-03-15 2009-12-01 Boston Scientific Neuromodulation Corporation Implantable stimulator
US20060235279A1 (en) 2005-03-18 2006-10-19 Hawkes David T Less invasive access port system and method for using the same
WO2006102605A2 (en) 2005-03-23 2006-09-28 Alphaspine, Inc. Percutaneous pedicle screw assembly
EP1866443A4 (en) 2005-04-04 2009-04-08 Blueshift Biotechnologies Inc Screening using polarization anisotropy in fret emissions
CN2782035Y (en) 2005-04-19 2006-05-24 杨惠林 Pourable vertebral arch root screw
US7758617B2 (en) 2005-04-27 2010-07-20 Globus Medical, Inc. Percutaneous vertebral stabilization system
US7491208B2 (en) * 2005-04-28 2009-02-17 Warsaw Orthopedic, Inc. Instrument and method for guiding surgical implants and instruments during surgery
US7515961B2 (en) 2005-04-29 2009-04-07 Medtronic, Inc. Method and apparatus for dynamically monitoring, detecting and diagnosing lead conditions
US7749233B2 (en) 2005-06-08 2010-07-06 Innovative Spine, Llc Sleeve assembly for spinal stabilization system and methods of use
US8068892B2 (en) 2005-06-16 2011-11-29 Aaken Labs Methods and systems for using intracranial electrodes
US9307925B2 (en) 2005-06-16 2016-04-12 Aaken Laboratories Methods and systems for generating electrical property maps of biological structures
WO2007002144A2 (en) 2005-06-23 2007-01-04 University Of Florida Research Foundation, Inc. Brain stimulation method for weight control
CA2613694A1 (en) 2005-07-01 2007-01-11 Carmen Bartic Means for functional restoration of a damaged nervous system
JP2009501571A (en) 2005-07-15 2009-01-22 チルドレンズ ホスピタル メディカル センター Spinal deformity correction from the dorsal side with minimal invasiveness
US7499752B2 (en) 2005-07-29 2009-03-03 Cyberonics, Inc. Selective nerve stimulation for the treatment of eating disorders
US7909830B2 (en) 2005-08-25 2011-03-22 Synthes Usa, Llc Methods of spinal fixation and instrumentation
KR20080074099A (en) 2005-09-12 2008-08-12 이모티브 시스템즈 피티와이 엘티디. Detection of and interaction using mental states
US20070073354A1 (en) 2005-09-26 2007-03-29 Knudson Mark B Neural blocking therapy
US7846093B2 (en) 2005-09-26 2010-12-07 K2M, Inc. Minimally invasive retractor and methods of use
US7805202B2 (en) 2005-09-30 2010-09-28 Boston Scientific Neuromodulation Corporation Implantable electrodes and insertion methods and tools
CN101316553B (en) 2005-10-06 2011-03-30 神经毫微股份公司 Electrode bundle
US20070093814A1 (en) 2005-10-11 2007-04-26 Callahan Ronald Ii Dynamic spinal stabilization systems
US20080015968A1 (en) 2005-10-14 2008-01-17 Leviathan Entertainment, Llc Fee-Based Priority Queuing for Insurance Claim Processing
US7555344B2 (en) 2005-10-28 2009-06-30 Cyberonics, Inc. Selective neurostimulation for treating epilepsy
US7684867B2 (en) 2005-11-01 2010-03-23 Boston Scientific Neuromodulation Corporation Treatment of aphasia by electrical stimulation and/or drug infusion
US20070106143A1 (en) 2005-11-08 2007-05-10 Flaherty J C Electrode arrays and related methods
US7575581B2 (en) 2005-12-07 2009-08-18 Blackstone Medical, Inc. Device for holding and inserting one or more components of a pedicle screw assembly
WO2007082157A2 (en) 2006-01-06 2007-07-19 C. R. Bard, Inc. Drains for use in medical applications and methods of using the same
US7927360B2 (en) 2006-01-26 2011-04-19 Warsaw Orthopedic, Inc. Spinal anchor assemblies having extended receivers
US7497869B2 (en) 2006-01-27 2009-03-03 Warsaw Orthopedic, Inc. Methods and devices for a minimally invasive placement of a rod within a patient
US8894655B2 (en) 2006-02-06 2014-11-25 Stryker Spine Rod contouring apparatus and method for percutaneous pedicle screw extension
US7520879B2 (en) 2006-02-07 2009-04-21 Warsaw Orthopedic, Inc. Surgical instruments and techniques for percutaneous placement of spinal stabilization elements
US7949410B2 (en) 2006-04-04 2011-05-24 Advanced Neuromodulation Systems, Inc. Burr hole cap and methods of use
AU2007238129A1 (en) 2006-04-11 2007-10-25 Synthes Gmbh Minimally invasive fixation system
US20070270815A1 (en) * 2006-04-20 2007-11-22 Chris Johnson Bone anchors with end-loading receivers for elongated connecting elements in spinal surgical procedures
US8696560B2 (en) 2006-05-02 2014-04-15 K2M, Inc. Minimally open retraction device
US8116875B2 (en) 2006-06-16 2012-02-14 Neuropoint Medical, Inc. Implantable neurostimulation systems
US8401654B1 (en) 2006-06-30 2013-03-19 Boston Scientific Neuromodulation Corporation Methods and systems for treating one or more effects of deafferentation
US7593776B2 (en) 2006-07-05 2009-09-22 University Of Southern California Flexible communication and control protocol for a wireless sensor and microstimulator network
US7583999B2 (en) 2006-07-31 2009-09-01 Cranial Medical Systems, Inc. Multi-channel connector for brain stimulation system
US7976546B2 (en) 2006-08-04 2011-07-12 Magrod, Llc Magnetic targeting system for facilitating navigation
US8644934B2 (en) 2006-09-13 2014-02-04 Boston Scientific Scimed Inc. Cardiac stimulation using leadless electrode assemblies
US20080071274A1 (en) 2006-09-15 2008-03-20 Ensign Michael D Percutaneous Screw Assembly and Placement Method
US9011447B2 (en) 2006-09-25 2015-04-21 Stryker Spine Rod contouring alignment linkage
US8038699B2 (en) 2006-09-26 2011-10-18 Ebi, Llc Percutaneous instrument assembly
US7947045B2 (en) * 2006-10-06 2011-05-24 Zimmer Spine, Inc. Spinal stabilization system with flexible guides
US20080086130A1 (en) 2006-10-06 2008-04-10 Depuy Spine, Inc. Torsionally stable fixation
US20080097519A1 (en) 2006-10-20 2008-04-24 Alfred E. Mann Foundation For Scientific Research Medical device extraction tool
US8052720B2 (en) 2006-11-09 2011-11-08 Zimmer Spine, Inc. Minimally invasive pedicle screw access system and associated method
US8262662B2 (en) 2006-11-20 2012-09-11 Depuy Spine, Inc. Break-off screw extensions
US20080119862A1 (en) 2006-11-21 2008-05-22 Wicker Meleah Ann Surgical Instrument for Supplying a Counter-Torque When Securing a Spinal Prosthesis
USD565735S1 (en) 2006-12-06 2008-04-01 Emotiv Systems Pty Ltd Electrode headset
US7931673B2 (en) 2006-12-06 2011-04-26 Zimmer Spine, Inc. Minimally invasive vertebral anchor access system and associated method
US8679128B2 (en) 2006-12-07 2014-03-25 Zimmer Spine, Inc. Apparatus and methods for reduction of vertebral bodies in a spine
US20080140132A1 (en) 2006-12-07 2008-06-12 Mi4Spine, Llc Pedicle screw and rod system for minimally invasive spinal fusion surgery
US9867640B2 (en) 2006-12-07 2018-01-16 Nexus Spine, LLC Press-on pedicle screw assembly
AU2007332794C1 (en) 2006-12-08 2012-01-12 Roger P. Jackson Tool system for dynamic spinal implants
US7917230B2 (en) 2007-01-30 2011-03-29 Cardiac Pacemakers, Inc. Neurostimulating lead having a stent-like anchor
US20080208074A1 (en) 2007-02-21 2008-08-28 David Snyder Methods and Systems for Characterizing and Generating a Patient-Specific Seizure Advisory System
US7563141B2 (en) 2007-02-26 2009-07-21 Medtronic, Inc. Implantable neurostimulator adapters
FR2912921B1 (en) 2007-02-26 2010-10-08 Commissariat Energie Atomique NON-RECTILINE PROBE AND SYSTEM FOR DEEP ELECTRICAL NEUROSTIMULATION COMPRISING SUCH A PROBE
US20080218472A1 (en) 2007-03-05 2008-09-11 Emotiv Systems Pty., Ltd. Interface to convert mental states and facial expressions to application input
US7945323B2 (en) 2007-04-13 2011-05-17 Boston Scientific Neuromodulation Corporation Treatment of obesity and/or type II diabetes by stimulation of the pituitary gland
US8979749B2 (en) 2007-04-17 2015-03-17 K2M, Inc. Minimally open interbody access retraction device and surgical method
CN101678204A (en) 2007-06-04 2010-03-24 皇家飞利浦电子股份有限公司 Insertion system and lead for treatment of a target tissue region
US8888820B2 (en) 2007-06-28 2014-11-18 Spinal Elements, Inc. Spinal stabilization device
US8043343B2 (en) 2007-06-28 2011-10-25 Zimmer Spine, Inc. Stabilization system and method
US8366652B2 (en) 2007-08-17 2013-02-05 The Invention Science Fund I, Llc Systems, devices, and methods including infection-fighting and monitoring shunts
US20090054955A1 (en) 2007-08-20 2009-02-26 Kopell Brian H Systems and Methods for Treating Neurological Disorders by Light Stimulation
US20090287061A1 (en) 2007-10-01 2009-11-19 Gft Technologies Surgical access device for minimally invasive surgery
US8366714B2 (en) 2007-10-23 2013-02-05 K2M, Inc. Rod insertion instrument and method of use
US20090112278A1 (en) 2007-10-30 2009-04-30 Neuropace, Inc. Systems, Methods and Devices for a Skull/Brain Interface
US20090118804A1 (en) 2007-11-05 2009-05-07 Advanced Bionics Corporation Method of mounting minimally invasive plug electrodes within cranium of patient
US20090125080A1 (en) 2007-11-12 2009-05-14 Montgomery Jr Erwin B Intraventricular electrodes for electrical stimulation of the brain
US20090259137A1 (en) 2007-11-14 2009-10-15 Emotiv Systems Pty Ltd Determination of biosensor contact quality
US20090171392A1 (en) 2007-12-04 2009-07-02 Javier Garcia-Bengochea Guide wire mounting collar for spinal fixation using minimally invasive surgical techniques
US8075579B2 (en) 2008-01-17 2011-12-13 Life Spine, Inc. Pedicle dart system
CN201157401Y (en) 2008-02-25 2008-12-03 梁道臣 Minimally invasive percutaneous transpedicular surgery positioning guide device
US20090216278A1 (en) 2008-02-25 2009-08-27 Dr. John K. Song Method and device for stabilization
US20090221879A1 (en) 2008-02-28 2009-09-03 K2M, Inc. Minimally Invasive Retractor Having Separable Blades
US20090222044A1 (en) 2008-02-28 2009-09-03 K2M, Inc. Minimally Invasive Retractor Screw and Methods of Use
US8246538B2 (en) 2008-02-28 2012-08-21 K2M, Inc. Minimally invasive retractor with separable blades and methods of use
US8097026B2 (en) 2008-02-28 2012-01-17 K2M, Inc. Minimally invasive retraction device having removable blades
US8747407B2 (en) 2008-02-28 2014-06-10 K2M, Inc. Minimally invasive retractor and methods of use
US20090234392A1 (en) 2008-03-13 2009-09-17 Depuy Spine, Inc. Method for inserting a spinal fixation element using implants having guide tabs
US8900248B2 (en) 2008-06-13 2014-12-02 The University Of Toledo Insertion assembly for minimally invasive spinal surgery
BRPI0920821B8 (en) 2008-10-01 2021-06-22 Hua Sherwin bone stabilization system and screw for use in bone stabilization
WO2011040986A1 (en) 2009-09-30 2011-04-07 Sherwin Hua System and method for offset guidance in pedicle screw stabilization of spinal vertebrae
US8075565B2 (en) * 2008-11-05 2011-12-13 Warsaw Orthopedic, Inc. Surgical instruments for delivering forces to bony structures
GB0821325D0 (en) 2008-11-21 2008-12-31 Ucl Business Plc Method and apparatus for performing deep brain stimulation with an electric field
US20100145176A1 (en) 2008-12-04 2010-06-10 Himes David M Universal Electrode Array for Monitoring Brain Activity
US8374703B2 (en) 2009-01-26 2013-02-12 Incube Labs, Llc Method and apparatus for the detection of aberrant neural-electric activity
US8246624B2 (en) 2009-07-23 2012-08-21 Zimmer Spine, Inc. Spinal rod insertion tool and method
US9770204B2 (en) 2009-11-11 2017-09-26 Medtronic, Inc. Deep brain stimulation for sleep and movement disorders
EP2515750A4 (en) 2009-12-21 2013-07-10 Sherwin Hua Insertion of medical devices through non-orthogonal and orthogonal trajectories within the cranium and methods of using
US8540719B2 (en) 2010-02-09 2013-09-24 Aesculap Implant Systems, Llc Percutaneous rod insertion system and method
KR101814838B1 (en) 2010-03-30 2018-01-03 셔윈 화 Systems and methods for pedicle screw stabilization of spinal vertebrae
WO2011133583A1 (en) 2010-04-19 2011-10-27 Functional Neuromodulation Inc. Deep brain stimulation of memory circuits in alzheimer's disease
CN102293680B (en) 2010-06-24 2014-04-16 华沙整形外科股份有限公司 Coplanar straightening system
WO2012103224A1 (en) 2011-01-25 2012-08-02 Medtronic, Inc. Target therapy delivery site selection
US9198698B1 (en) 2011-02-10 2015-12-01 Nuvasive, Inc. Minimally invasive spinal fixation system and related methods
WO2013063111A1 (en) 2011-10-24 2013-05-02 Purdue Research Foundation Method and apparatus for closed-loop control of nerve activation
US11166707B2 (en) 2011-12-20 2021-11-09 Life Spine, Inc. Retractor with modular tap assemblies
US9125703B2 (en) 2012-01-16 2015-09-08 K2M, Inc. Rod reducer, compressor, distractor system
US9919148B2 (en) 2012-05-25 2018-03-20 Boston Scientific Neuromodulation Corporation Distally curved electrical stimulation lead and methods of making and using
US10098665B2 (en) 2012-08-01 2018-10-16 DePuy Synthes Products, Inc. Spine derotation system
US9622785B2 (en) 2012-09-04 2017-04-18 Ignacio Sanpera Trigueros System and method for a global three-dimensional correction of the curvatures of the spine
US10004543B2 (en) 2013-02-04 2018-06-26 Genesys Spine Minimally invasive pedicle screw extension sleeve system
JP6449844B2 (en) 2013-03-14 2019-01-09 インキューブ ラブズ， エルエルシー Devices, systems and methods for delivery of drugs to the brain for treating neurological symptoms
US9510875B2 (en) 2013-03-14 2016-12-06 Stryker European Holdings I, Llc Systems and methods for percutaneous spinal fusion
US9919146B2 (en) 2013-05-01 2018-03-20 Sherwin Hua Methods and systems for intraventricular brain stimulation
US9402660B2 (en) 2013-09-05 2016-08-02 Warsaw Orthopedic, Inc. Surgical instrument and method
US9402661B2 (en) 2013-09-23 2016-08-02 Stryker European Holdings I, LCC Lumbar-sacral screw insertion and manipulation
WO2015079324A2 (en) 2013-10-18 2015-06-04 Functional Neuromodulation, Inc. Brain stimulation system including diagnostic tool
WO2015149170A1 (en) 2014-03-31 2015-10-08 Functional Neuromodulation, Inc. Systems and methods for determining a trajectory for a brain stimulation lead
US10022172B2 (en) 2014-06-25 2018-07-17 Spine Wave, Inc. Minimally invasive posterolateral fusion
EP3180080B1 (en) 2014-08-14 2021-01-06 Functional Neuromodulation, Inc. Brain stimulation system including multiple stimulation modes
US20160166326A1 (en) 2014-11-25 2016-06-16 Medtronic Bakken Research Center B.V. Medical lead bending sensor
US9877846B2 (en) 2015-01-20 2018-01-30 Warsaw Orthopedic, Inc. Spinal implant system and method
US20160228693A1 (en) 2015-02-09 2016-08-11 Arnold B. Vardiman Bilateral deep brain stimulator
GB201506052D0 (en) 2015-04-09 2015-05-27 Renishaw Plc Movement disorder
US9615855B2 (en) 2015-05-15 2017-04-11 Baui Biotech Co., Ltd. Bone screw and percutaneous minimally invasive pedicle fixation system
GB201510781D0 (en) 2015-06-19 2015-08-05 Bioinduction Ltd Method and device for deep brain stimulation
AU2016316683B2 (en) 2015-09-04 2020-07-23 The Johns Hopkins University Low-profile intercranial device
US9724515B2 (en) 2015-10-29 2017-08-08 Rainbow Medical Ltd. Electrical substance clearance from the brain for treatment of Alzheimer's disease
US10194960B1 (en) 2015-12-03 2019-02-05 Nuvasive, Inc. Spinal compression instrument and related methods
EP3411111A1 (en) 2016-02-02 2018-12-12 Aleva Neurotherapeutics SA Treatment of autoimmune diseases with deep brain stimulation
TWI637721B (en) 2016-09-12 2018-10-11 台灣微創醫療器材股份有限公司 Spinal surgical tool
US9867978B1 (en) 2016-09-16 2018-01-16 Precision Neurotechnologies Llc Conformal electrode arrays for electrophysiologic recording and neural stimulation within the cerebral ventricles
TWI649064B (en) 2017-09-07 2019-02-01 台灣微創醫療器材股份有限公司 Device for surgery of stabilizing bone segments and extending assembly thereof
US20190231394A1 (en) 2018-01-29 2019-08-01 Globus Medical, Inc. Compressor/distractor
TWM566547U (en) 2018-03-21 2018-09-11 裕晟生物醫學股份有限公司 Intramedullary nail structure
TWI682761B (en) 2018-10-09 2020-01-21 台灣微創醫療器材股份有限公司 Device for surgery of stabilizing bone segments, extending assembly, fastening member and assembing method thereof
US10660631B1 (en) 2018-12-13 2020-05-26 Invictus Development & Engineering, Inc. Pedicle screw mounted retractor system
US11160580B2 (en) 2019-04-24 2021-11-02 Spine23 Inc. Systems and methods for pedicle screw stabilization of spinal vertebrae
WO2021092495A1 (en) 2019-11-08 2021-05-14 Spine 23, Inc. Systems and methods for pedicle screw stabilization of spinal vertebrae
CN115551426A (en) 2019-11-27 2022-12-30 斯拜因23公司 Systems, devices and methods for treating scoliosis

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8216282B2 (en) 2008-10-01 2012-07-10 Sherwin Hua System and method for wire-guided pedicle screw stabilization of spinal vertebrae
US8333770B2 (en) 2008-10-01 2012-12-18 Sherwin Hua Systems and methods for pedicle screw stabilization of spinal vertebrae
US8721691B2 (en) 2008-10-01 2014-05-13 Sherwin Hua Systems and methods for pedicle screw stabilization of spinal vertebrae

Also Published As

Publication number Publication date
BRPI0920821B8 (en) 2021-06-22
JP5795534B2 (en) 2015-10-14
US8216282B2 (en) 2012-07-10
WO2010039817A2 (en) 2010-04-08
US11759238B2 (en) 2023-09-19
ES2462759T3 (en) 2014-05-26
US20110282390A1 (en) 2011-11-17
CN102186433A (en) 2011-09-14
AU2009298554A1 (en) 2010-04-08
AU2017245407A1 (en) 2017-11-02
KR20110081224A (en) 2011-07-13
US20110270324A1 (en) 2011-11-03
US10973551B2 (en) 2021-04-13
CA2739431A1 (en) 2010-04-08
RU2011113701A (en) 2012-11-10
US20210000510A1 (en) 2021-01-07
AU2009298554B2 (en) 2016-03-31
RU2513155C2 (en) 2014-04-20
MX345890B (en) 2017-02-22
AU2016201395A1 (en) 2016-03-24
EP2341858A2 (en) 2011-07-13
EP2341858A4 (en) 2012-07-04
KR101679088B1 (en) 2016-12-06
BRPI0920821B1 (en) 2020-09-29
US20110196429A1 (en) 2011-08-11
MX2011003046A (en) 2011-09-01
AU2019210492A1 (en) 2019-08-15
BRPI0920821A2 (en) 2015-12-22
WO2010039817A3 (en) 2010-07-22
AU2016201395B2 (en) 2017-10-26
JP2012504464A (en) 2012-02-23
CN102186433B (en) 2014-12-10
US20120016423A1 (en) 2012-01-19
US8556940B2 (en) 2013-10-15
US8545541B2 (en) 2013-10-01
CA2739431C (en) 2016-12-06
AU2017245407B2 (en) 2019-05-02
EP2341858B1 (en) 2014-02-12

Similar Documents

Publication Publication Date Title
WO2010039817A4 (en) System and method for wire-guided pedicle screw stabilization of spinal vertebrae
US20200197053A1 (en) Reduction sleeve
US10856910B2 (en) System and method for insertion of flexible spinal stabilization element
EP3254634B1 (en) Paraxial revision rod-to-rod connector
US7967849B2 (en) Adjustable multi-axial spinal coupling assemblies
US8025682B2 (en) Method and system for securing a rod to a bone anchor with a connector
US7648521B2 (en) System and method for minimally invasive spinal surgery
US9439692B1 (en) Minimally invasive spinal fixation system and method therefor
US20090234392A1 (en) Method for inserting a spinal fixation element using implants having guide tabs
CN107530110B (en) Thin layer implants and methods for spinal decompression
US8906064B2 (en) Interspinous process device and method
WO2011040986A1 (en) System and method for offset guidance in pedicle screw stabilization of spinal vertebrae
US20110082505A1 (en) Implant system and minimally invasive method for immobilizing adjacent vertebral bodies
US20200022734A1 (en) Apparatus, system, and method for spinal vertebrae stabilization

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200980140693.1

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 09818436

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: MX/A/2011/003046

Country of ref document: MX

WWE Wipo information: entry into national phase

Ref document number: 2011530168

Country of ref document: JP

Ref document number: 2009818436

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2739431

Country of ref document: CA

Ref document number: 13122388

Country of ref document: US

WWE Wipo information: entry into national phase

Ref document number: 667/MUMNP/2011

Country of ref document: IN

WWE Wipo information: entry into national phase

Ref document number: 2009298554

Country of ref document: AU

ENP Entry into the national phase

Ref document number: 20117009465

Country of ref document: KR

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 2011113701

Country of ref document: RU

ENP Entry into the national phase

Ref document number: 2009298554

Country of ref document: AU

Date of ref document: 20090930

Kind code of ref document: A

ENP Entry into the national phase

Ref document number: PI0920821

Country of ref document: BR

Kind code of ref document: A2

Effective date: 20110401