WO2010039654A3 - Topical treatment of skin infection - Google Patents

Topical treatment of skin infection Download PDF

Info

Publication number
WO2010039654A3
WO2010039654A3 PCT/US2009/058607 US2009058607W WO2010039654A3 WO 2010039654 A3 WO2010039654 A3 WO 2010039654A3 US 2009058607 W US2009058607 W US 2009058607W WO 2010039654 A3 WO2010039654 A3 WO 2010039654A3
Authority
WO
WIPO (PCT)
Prior art keywords
propylene glycol
topical treatment
skin infection
killing
salicylic acid
Prior art date
Application number
PCT/US2009/058607
Other languages
French (fr)
Other versions
WO2010039654A2 (en
Inventor
Win L. Chiou
Original Assignee
Chiou Win L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiou Win L filed Critical Chiou Win L
Priority to GB1107350A priority Critical patent/GB2476446A/en
Priority to JP2011530129A priority patent/JP2012504624A/en
Priority to CN2009801367528A priority patent/CN102159198A/en
Priority to CA2742389A priority patent/CA2742389A1/en
Publication of WO2010039654A2 publication Critical patent/WO2010039654A2/en
Publication of WO2010039654A3 publication Critical patent/WO2010039654A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers

Abstract

The invention relates to an unexpected discovery that propylene glycol is highly effective at killing or inhibiting Propionibacterium acnes in a mammalian skin disorder, as well as to the use of propylene glycol and salicylic acid in a skin- disorder treatment. This invention also relates to compositions containing propylene glycol alone or in combination with salicylic acid for use in killing or inhibiting Propionibacterium acnes.
PCT/US2009/058607 2008-10-03 2009-09-28 Topical treatment of skin infection WO2010039654A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
GB1107350A GB2476446A (en) 2008-10-03 2009-09-28 Topical treatment of skin infection
JP2011530129A JP2012504624A (en) 2008-10-03 2009-09-28 Topical treatment of skin infections
CN2009801367528A CN102159198A (en) 2008-10-03 2009-09-28 Topical treatment of skin infection
CA2742389A CA2742389A1 (en) 2008-10-03 2009-09-28 Topical treatment of skin infection

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/244,924 2008-10-03
US12/244,924 US8846646B2 (en) 2008-10-03 2008-10-03 Topical treatment of skin infection

Publications (2)

Publication Number Publication Date
WO2010039654A2 WO2010039654A2 (en) 2010-04-08
WO2010039654A3 true WO2010039654A3 (en) 2010-07-01

Family

ID=42074140

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/058607 WO2010039654A2 (en) 2008-10-03 2009-09-28 Topical treatment of skin infection

Country Status (7)

Country Link
US (1) US8846646B2 (en)
JP (1) JP2012504624A (en)
KR (1) KR20110074513A (en)
CN (1) CN102159198A (en)
CA (1) CA2742389A1 (en)
GB (1) GB2476446A (en)
WO (1) WO2010039654A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8513225B2 (en) * 2008-10-03 2013-08-20 Winlind Skincare, Llc Composition and method for topical treatment of skin lesions
US8846646B2 (en) 2008-10-03 2014-09-30 Winlind Skincare, Llc Topical treatment of skin infection
GB201112657D0 (en) * 2011-07-22 2011-09-07 Lowe Nicholas J Compositions for treatment of skin disorders
CN103816165B (en) * 2014-03-11 2019-03-01 北京德默高科医药技术有限公司 A kind of composition for treating acne
DK3010511T3 (en) 2014-09-12 2018-03-05 Antibiotx As ANTIBACTERIAL USE OF HALOGENERED SALICYLANILIDES
GB201509326D0 (en) 2015-05-29 2015-07-15 Antibio Tx Aps Novel use
US10456366B2 (en) * 2017-11-29 2019-10-29 Chiou Consulting, Inc. Composition and methods for tissue regeneration
US11419834B2 (en) 2019-02-25 2022-08-23 Rhode Island Hospital Methods for treating diseases or infections caused by or associated with H. pylori using a halogenated salicylanilide
CN112438899A (en) * 2020-12-16 2021-03-05 广东丸美生物技术股份有限公司 Skin care composition with acne conditioning effect and application thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4767750A (en) * 1985-05-07 1988-08-30 L'oreal Topical compositions intended for skin treatment containing salicylic acid derivatives
US5549888A (en) * 1994-01-31 1996-08-27 Procter & Gamble Aqueous topical anti-acne compositions of low pH
US6455065B1 (en) * 1999-05-18 2002-09-24 Lectec Corporation Therapeutic method for treating acne or isolated pimples and adhesive patch therefor

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5525635A (en) * 1986-02-04 1996-06-11 Moberg; Sven Pharmaceutical compositions containing propylene glycol and/or polyethylene glycol and urea as active main components and use thereof
US4883660A (en) * 1988-10-17 1989-11-28 Thames Pharmacal Co., Inc. Gel bases for pharmaceutical compositions
US5569651A (en) * 1995-03-03 1996-10-29 Avon Products, Inc. Gentle anti-acne composition
US5667790A (en) * 1995-08-14 1997-09-16 Sellers, Jr.; Billy B. Aluminum chlorhydrate as a treatment for acne and rosacea
US5753637A (en) * 1996-10-09 1998-05-19 Ideal Ideas, Inc. Method of treating acne conditions
US6616923B1 (en) * 2002-07-26 2003-09-09 Chiou Consulting, Inc. Aqueous compositions for facial cosmetics
US7887842B2 (en) * 2003-02-07 2011-02-15 Teikoku Pharma Usa, Inc. Methods of administering a dermatological agent to a subject
US7258875B2 (en) * 2003-12-04 2007-08-21 Chiou Consulting, Inc. Compositions and methods for topical treatment of skin infection
US8846646B2 (en) 2008-10-03 2014-09-30 Winlind Skincare, Llc Topical treatment of skin infection

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4767750A (en) * 1985-05-07 1988-08-30 L'oreal Topical compositions intended for skin treatment containing salicylic acid derivatives
US5549888A (en) * 1994-01-31 1996-08-27 Procter & Gamble Aqueous topical anti-acne compositions of low pH
US6455065B1 (en) * 1999-05-18 2002-09-24 Lectec Corporation Therapeutic method for treating acne or isolated pimples and adhesive patch therefor

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CARREIRA, C. M. ET AL.: "Antimicrobial effect of intracanal substances", JOURNAL OF APPLIED ORAL SCIENCE., vol. 15, no. 5, 2007, pages 453 - 458 *
CHIRIFE, J. ET AL.: "In vitro antibacterial activity of concentrated polyethylene glycol 400 solutions", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY., vol. 24, no. 3, 1983, pages 409 - 412 *

Also Published As

Publication number Publication date
JP2012504624A (en) 2012-02-23
KR20110074513A (en) 2011-06-30
CN102159198A (en) 2011-08-17
GB201107350D0 (en) 2011-06-15
WO2010039654A2 (en) 2010-04-08
GB2476446A (en) 2011-06-22
CA2742389A1 (en) 2010-04-08
US8846646B2 (en) 2014-09-30
US20100087403A1 (en) 2010-04-08

Similar Documents

Publication Publication Date Title
WO2010039654A3 (en) Topical treatment of skin infection
WO2014113429A3 (en) Substituted pyrrolopyrimidine compounds, compositions thereof, and methods of treatment therewith
MY188960A (en) Cyclic boronic acid ester derivatives and therapeutic uses thereof
WO2014062720A3 (en) Methods of treating cancer
WO2014062733A3 (en) Substituted benzene compounds
WO2010087964A3 (en) Compositions for treatment and prevention of acne, methods of making the compositions, and methods of use thereof
WO2014028589A3 (en) 4-HETEROARYL SUBSTITUTED BENZOIC ACID COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF
CA2894892A1 (en) Boronic acid derivatives and therapeutic uses thereof
WO2015023976A3 (en) Selective grp94 inhibitors and uses thereof
MY153948A (en) Substituted-quinoxaline-type bridged-piperidine compounds and the uses thereof
NZ597542A (en) Topical composition containing ibuprofen
WO2012154122A3 (en) A topical formulation for treatment of hyperkeratotic skin
WO2011159840A3 (en) Phenylthioacetate compounds, compositions and methods of use
WO2011140310A3 (en) Povidone-iodine topical composition
UA99101C2 (en) Composition for topical skin care comprising compounds of glyceryl di- and monosalycylate
NZ708453A (en) Germicidal compositions comprising carboxylic acid mixture and use as topical disinfectants
NZ596628A (en) Ketolide compounds having antimicrobial activity
MX2012013606A (en) Tamarind seed polysaccharide for use in the treatment of microbial infections.
WO2012007776A3 (en) Disinfectant and antiseptic formulation having reduced iodine content
UA107687C2 (en) A combined composition comprising as active ingredients l-carnitine or propionyl l-carnitine, troxerutine, diosmlne and hesperidine, for the prevention and/or treatment of chronic venous diseases
WO2011049327A3 (en) A skin external composition comprising a salt and sugar as active ingredients for preventing and treating vaginosis and the use thereof
EA201401031A1 (en) A HALF-LEVELED COMPOSITION FOR LOCAL APPLICATION THAT CONTAINS Pyrphenidone and Modified Diallyldisulfide Oxide (M-DDO) to Remove or Prevent Ugrey
WO2014182789A3 (en) Radiomitigating pharmaceutical formulations
MX359713B (en) Improved wound healing compositions comprising microspheres.
WO2013092457A3 (en) Active agent combinations of one or more carboxylic acids, in particular hydroxycarboxylic acids, and of one or more physiologically harmless hydroxamic acids, and cosmetic or dermatological preparations containing such active agent combinations

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200980136752.8

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 09818334

Country of ref document: EP

Kind code of ref document: A2

ENP Entry into the national phase

Ref document number: 20117006688

Country of ref document: KR

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 2011530129

Country of ref document: JP

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 1584/KOLNP/2011

Country of ref document: IN

WWE Wipo information: entry into national phase

Ref document number: 2742389

Country of ref document: CA

ENP Entry into the national phase

Ref document number: 1107350

Country of ref document: GB

Kind code of ref document: A

Free format text: PCT FILING DATE = 20090928

WWE Wipo information: entry into national phase

Ref document number: 1107350.9

Country of ref document: GB

122 Ep: pct application non-entry in european phase

Ref document number: 09818334

Country of ref document: EP

Kind code of ref document: A2