WO2010004361A3 - Compositions and methods for improving overall tooth health and appearance - Google Patents

Compositions and methods for improving overall tooth health and appearance Download PDF

Info

Publication number
WO2010004361A3
WO2010004361A3 PCT/IB2008/052562 IB2008052562W WO2010004361A3 WO 2010004361 A3 WO2010004361 A3 WO 2010004361A3 IB 2008052562 W IB2008052562 W IB 2008052562W WO 2010004361 A3 WO2010004361 A3 WO 2010004361A3
Authority
WO
WIPO (PCT)
Prior art keywords
teeth
appearance
methods
calcium
acids
Prior art date
Application number
PCT/IB2008/052562
Other languages
French (fr)
Other versions
WO2010004361A2 (en
Inventor
Arif Ali Baig
Robert Vincent Faller
George Endel Deckner
Original Assignee
The Procter & Gamble Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Procter & Gamble Company filed Critical The Procter & Gamble Company
Priority to CN200880129675.9A priority Critical patent/CN102056648B/en
Priority to BRPI0822894A priority patent/BRPI0822894B1/en
Priority to CA2726077A priority patent/CA2726077C/en
Priority to MX2010014220A priority patent/MX2010014220A/en
Priority to JP2011513062A priority patent/JP5631870B2/en
Priority to AU2008359213A priority patent/AU2008359213B2/en
Priority to EP08789160.2A priority patent/EP2293850B1/en
Publication of WO2010004361A2 publication Critical patent/WO2010004361A2/en
Publication of WO2010004361A3 publication Critical patent/WO2010004361A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/60—Preparations for dentistry comprising organic or organo-metallic additives
    • A61K6/69—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20—Halogens; Compounds thereof
    • A61K8/21—Fluorides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24—Phosphorous; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A61K8/416—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A61K8/556—Derivatives containing from 2 to 10 oxyalkylene groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/335—Polymers modified by chemical after-treatment with organic compounds containing phosphorus
    • C08G65/3353—Polymers modified by chemical after-treatment with organic compounds containing phosphorus containing oxygen in addition to phosphorus
    • C08G65/3355—Polymers modified by chemical after-treatment with organic compounds containing phosphorus containing oxygen in addition to phosphorus having phosphorus bound to carbon and oxygen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides

Abstract

Disclosed are oral care compositions comprising selected surface-active organophosphate compounds and methods of use to provide protection of teeth from erosion caused by the action of chemicals, such as harsh abrasives and acids. The surface-active organophosphate compounds are substantive to teeth, the phosphate groups binding the calcium in teeth and thus preventing loss of calcium from dissolution when contacted with acids. The organophosphate compound may also deposit a protective surface coating that prevents contact of teeth with erosive challenges. Selected organophosphate compounds contain one or more phosphate groups and are combined in the oral care composition with one or more of a fluoride ion agent, an antimicrobial agent preferably selected from quaternary ammonium compounds and polyvalent metal salts, an anticalculus agent and additional surfactant, to provide benefits including superior anti-erosion, anticaries, antiplaque and anti-staining as demonstrated by enhanced fluoride uptake, remineralization, resistance to acid demineralization and antimicrobial activities, resulting in improved overall tooth health, structural integrity and appearance.
PCT/IB2008/052562 2008-06-17 2008-06-25 Compositions and methods for improving overall tooth health and appearance WO2010004361A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
CN200880129675.9A CN102056648B (en) 2008-06-17 2008-06-25 Compositions and methods for improving overall tooth health and appearance
BRPI0822894A BRPI0822894B1 (en) 2008-06-17 2008-06-25 oral care compositions to protect an individual's teeth from erosion
CA2726077A CA2726077C (en) 2008-06-17 2008-06-25 Compositions and methods for improving overall tooth health and appearance
MX2010014220A MX2010014220A (en) 2008-06-17 2008-06-25 Compositions and methods for improving overall tooth health and appearance.
JP2011513062A JP5631870B2 (en) 2008-06-17 2008-06-25 Compositions and methods for improving general dental health and appearance
AU2008359213A AU2008359213B2 (en) 2008-06-17 2008-06-25 Compositions and methods for improving overall tooth health and appearance
EP08789160.2A EP2293850B1 (en) 2008-06-17 2008-06-25 Compositions and methods for improving overall tooth health and appearance

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/140,501 2008-06-17
US12/140,501 US9139731B2 (en) 1999-11-12 2008-06-17 Compositions and methods for improving overall tooth health and appearance

Publications (2)

Publication Number Publication Date
WO2010004361A2 WO2010004361A2 (en) 2010-01-14
WO2010004361A3 true WO2010004361A3 (en) 2010-09-10

Family

ID=41507488

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2008/052562 WO2010004361A2 (en) 2008-06-17 2008-06-25 Compositions and methods for improving overall tooth health and appearance

Country Status (11)

Country Link
US (2) US9139731B2 (en)
EP (1) EP2293850B1 (en)
JP (1) JP5631870B2 (en)
KR (1) KR20110005736A (en)
CN (1) CN102056648B (en)
AU (1) AU2008359213B2 (en)
BR (1) BRPI0822894B1 (en)
CA (1) CA2726077C (en)
MX (1) MX2010014220A (en)
RU (1) RU2010148562A (en)
WO (1) WO2010004361A2 (en)

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Also Published As

Publication number Publication date
BRPI0822894A2 (en) 2015-06-30
JP5631870B2 (en) 2014-11-26
AU2008359213B2 (en) 2015-01-15
AU2008359213A1 (en) 2010-01-14
JP2011522871A (en) 2011-08-04
EP2293850A2 (en) 2011-03-16
US9139731B2 (en) 2015-09-22
CA2726077A1 (en) 2010-01-14
KR20110005736A (en) 2011-01-18
MX2010014220A (en) 2011-01-21
CN102056648B (en) 2014-11-05
RU2010148562A (en) 2012-07-27
US9161895B1 (en) 2015-10-20
EP2293850B1 (en) 2019-01-02
CA2726077C (en) 2014-11-18
CN102056648A (en) 2011-05-11
WO2010004361A2 (en) 2010-01-14
BRPI0822894B1 (en) 2016-10-18
US20080247973A1 (en) 2008-10-09

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