WO2009143504A3 - Methods of microrna detection and differentiation - Google Patents

Methods of microrna detection and differentiation Download PDF

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Publication number
WO2009143504A3
WO2009143504A3 PCT/US2009/045111 US2009045111W WO2009143504A3 WO 2009143504 A3 WO2009143504 A3 WO 2009143504A3 US 2009045111 W US2009045111 W US 2009045111W WO 2009143504 A3 WO2009143504 A3 WO 2009143504A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
differentiation
microrna detection
sers
systems
Prior art date
Application number
PCT/US2009/045111
Other languages
French (fr)
Other versions
WO2009143504A2 (en
Inventor
Yiping Zhao
Ralph A. Tripp
Richard Dluhy
Anita Seto
Jeremy Driskell
Original Assignee
University Of Georgia Research Foundation, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Georgia Research Foundation, Inc. filed Critical University Of Georgia Research Foundation, Inc.
Publication of WO2009143504A2 publication Critical patent/WO2009143504A2/en
Publication of WO2009143504A3 publication Critical patent/WO2009143504A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection

Abstract

Embodiments of the present disclosure relate to surface-enhanced Raman spectroscopic (SERS) systems and methods of using the SERS systems to identify and differentiate an analyte.
PCT/US2009/045111 2008-05-23 2009-05-26 Methods of microrna detection and differentiation WO2009143504A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5547708P 2008-05-23 2008-05-23
US61/055,477 2008-05-23

Publications (2)

Publication Number Publication Date
WO2009143504A2 WO2009143504A2 (en) 2009-11-26
WO2009143504A3 true WO2009143504A3 (en) 2010-02-25

Family

ID=41340948

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/045111 WO2009143504A2 (en) 2008-05-23 2009-05-26 Methods of microrna detection and differentiation

Country Status (1)

Country Link
WO (1) WO2009143504A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103447523B (en) * 2013-09-12 2015-04-29 中国科学院合肥物质科学研究院 Gold nanoparticle-silver nano-semisphere array as well as preparation method and application thereof
CN108535236B (en) * 2018-03-30 2020-06-30 华南师范大学 Method for ultrasensitively detecting miRNA based on dual-amplification SERS signal system

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030187237A1 (en) * 2002-03-26 2003-10-02 Selena Chan Methods and device for DNA sequencing using surface enhanced raman scattering (SERS)
US20040180379A1 (en) * 2002-08-30 2004-09-16 Northwestern University Surface-enhanced raman nanobiosensor
US20060252065A1 (en) * 2004-10-21 2006-11-09 Yiping Zhao Surface enhanced Raman spectroscopy (SERS) systems, substrates, fabrication thereof, and methods of use thereof
US20080032420A1 (en) * 2004-03-30 2008-02-07 Lambert James L Surface Enhanced Raman Scattering and Multiplexed Diagnostic Assays

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030187237A1 (en) * 2002-03-26 2003-10-02 Selena Chan Methods and device for DNA sequencing using surface enhanced raman scattering (SERS)
US20040180379A1 (en) * 2002-08-30 2004-09-16 Northwestern University Surface-enhanced raman nanobiosensor
US20080032420A1 (en) * 2004-03-30 2008-02-07 Lambert James L Surface Enhanced Raman Scattering and Multiplexed Diagnostic Assays
US20060252065A1 (en) * 2004-10-21 2006-11-09 Yiping Zhao Surface enhanced Raman spectroscopy (SERS) systems, substrates, fabrication thereof, and methods of use thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
AOUNE BARHOUMI ET AL.: "Surface-Enhanced Raman Spectroscopy of DNA.", J. AM. CHEM. SOC., vol. 130, no. 16, 29 March 2008 (2008-03-29), pages 5523 - 5529 *
GARY BRAUN ET AL.: "Surface-Enhanced Raman Spectroscopy for DNA Detection by Nanoparticle Assembly onto Smooth Metal Films.", J. AM. CHEM. SOC., vol. 129, no. 20, 2007, pages 6378 - 6379 *
STEVEN E. J. BELL ET AL.: "Surface-Enhanced Raman Spectroscopy (SERS) for Sub-Micromolar Detection ofDNA/RNA Mononucleotides.", J. AM. CHEM. SOC., vol. 128, no. 49, 2006, pages 15580 - 15581 *

Also Published As

Publication number Publication date
WO2009143504A2 (en) 2009-11-26

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