WO2009108760A8 - Dendritic macroporous hydrogels prepared by crystal templating - Google Patents

Dendritic macroporous hydrogels prepared by crystal templating Download PDF

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Publication number
WO2009108760A8
WO2009108760A8 PCT/US2009/035257 US2009035257W WO2009108760A8 WO 2009108760 A8 WO2009108760 A8 WO 2009108760A8 US 2009035257 W US2009035257 W US 2009035257W WO 2009108760 A8 WO2009108760 A8 WO 2009108760A8
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WO
WIPO (PCT)
Prior art keywords
polymer
mixture
hydrogel
crystal structure
hydrogels prepared
Prior art date
Application number
PCT/US2009/035257
Other languages
French (fr)
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WO2009108760A3 (en
WO2009108760A2 (en
Inventor
Scott Zawko
Christine Schmidt
Original Assignee
Board Of Regents, The University Of Texas System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Board Of Regents, The University Of Texas System filed Critical Board Of Regents, The University Of Texas System
Priority to US12/919,667 priority Critical patent/US8668863B2/en
Publication of WO2009108760A2 publication Critical patent/WO2009108760A2/en
Publication of WO2009108760A3 publication Critical patent/WO2009108760A3/en
Publication of WO2009108760A8 publication Critical patent/WO2009108760A8/en
Priority to US13/909,707 priority patent/US8728499B2/en
Priority to US14/277,170 priority patent/US9320827B2/en
Priority to US15/135,978 priority patent/US9896561B2/en
Priority to US15/890,719 priority patent/US10442911B2/en
Priority to US16/597,106 priority patent/US10982068B2/en
Priority to US17/231,653 priority patent/US11760858B2/en
Priority to US18/361,981 priority patent/US20230383086A1/en

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    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/26—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by elimination of a solid phase from a macromolecular composition or article, e.g. leaching out
    • A—HUMAN NECESSITIES
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    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
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    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0095—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
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    • C08J3/26—Crosslinking, e.g. vulcanising, of macromolecules of latex

Abstract

The present invention includes a hydrogel and a method of making a porous hydrogel by preparing an aqueous mixture of an uncrosslinked polymer and a crystallizable molecule; casting the mixture into a vessel; allowing the cast mixture to dry to form an amorphous hydrogel film; seeding the cast mixture with a seed crystal of the crystallizable molecule; growing the crystallizable molecule into a crystal structure within the uncrosslinked polymer; crosslinking the polymer around the crystal structure under conditions in which the crystal structure within the crosslinked polymer is maintained; and dissolving the crystals within the crosslinked polymer to form the porous hydrogel.
PCT/US2009/035257 2008-02-26 2009-02-26 Dendritic macroporous hydrogels prepared by crystal templating WO2009108760A2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
US12/919,667 US8668863B2 (en) 2008-02-26 2009-02-26 Dendritic macroporous hydrogels prepared by crystal templating
US13/909,707 US8728499B2 (en) 2008-02-26 2013-06-04 Dendritic macroporous hydrogels prepared by crystal templating
US14/277,170 US9320827B2 (en) 2008-02-26 2014-05-14 Dendritic macroporous hydrogels prepared by crystal templating
US15/135,978 US9896561B2 (en) 2008-02-26 2016-04-22 Dendritic macroporous hydrogels prepared by crystal templating
US15/890,719 US10442911B2 (en) 2008-02-26 2018-02-07 Dendritic macroporous hydrogels prepared by crystal templating
US16/597,106 US10982068B2 (en) 2008-02-26 2019-10-09 Dendritic macroporous hydrogels prepared by crystal templating
US17/231,653 US11760858B2 (en) 2008-02-26 2021-04-15 Dendritic macroporous hydrogels prepared by crystal templating
US18/361,981 US20230383086A1 (en) 2008-02-26 2023-07-31 Dendritic Macroporous Hydrogels Prepared By Crystal Templating

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3165108P 2008-02-26 2008-02-26
US61/031,651 2008-02-26

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US20110008442A1 (en) 2011-01-13
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