WO2009085576A3 - Positive control cell pellets for immunohistochemistry and methods of use thereof - Google Patents

Positive control cell pellets for immunohistochemistry and methods of use thereof Download PDF

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Publication number
WO2009085576A3
WO2009085576A3 PCT/US2008/085844 US2008085844W WO2009085576A3 WO 2009085576 A3 WO2009085576 A3 WO 2009085576A3 US 2008085844 W US2008085844 W US 2008085844W WO 2009085576 A3 WO2009085576 A3 WO 2009085576A3
Authority
WO
WIPO (PCT)
Prior art keywords
cell pellets
control cell
positive control
immunohistochemistry
methods
Prior art date
Application number
PCT/US2008/085844
Other languages
French (fr)
Other versions
WO2009085576A2 (en
Inventor
Marc E. Key
Original Assignee
Spring Bioscience Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spring Bioscience Corporation filed Critical Spring Bioscience Corporation
Publication of WO2009085576A2 publication Critical patent/WO2009085576A2/en
Publication of WO2009085576A3 publication Critical patent/WO2009085576A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/5436—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand physically entrapped within the solid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides

Abstract

Described herein are control cell pellets for use in immunohistochemistry assays. This disclosure provides universal positive control cell pellets that can be used as positive staining controls for any immunohistochemistry assay, regardless of the antigen of interest. In one example, the universal positive control cells are cells expressing mouse immunoglobulin. Further provided are antigen-retrieval positive control cell pellets and endogenous peroxidase control cell pellets. As described herein, one or more of the control cell pellets can be prepared and placed on the same slide as the test sample to allow for simultaneous processing under identical conditions. In one example, the control cell pellets are immobilized on a detachable surface that allows the cell pellet to be removed and subsequently adhered to a second surface.
PCT/US2008/085844 2007-12-28 2008-12-08 Positive control cell pellets for immunohistochemistry and methods of use thereof WO2009085576A2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US942607P 2007-12-28 2007-12-28
US936007P 2007-12-28 2007-12-28
US942007P 2007-12-28 2007-12-28
US61/009,420 2007-12-28
US61/009,360 2007-12-28
US61/009,426 2007-12-28

Publications (2)

Publication Number Publication Date
WO2009085576A2 WO2009085576A2 (en) 2009-07-09
WO2009085576A3 true WO2009085576A3 (en) 2009-09-24

Family

ID=40824978

Family Applications (3)

Application Number Title Priority Date Filing Date
PCT/US2008/085833 WO2009085573A2 (en) 2007-12-28 2008-12-08 Quality control cell device for immunohistochemistry assay and methods of use thereof
PCT/US2008/085844 WO2009085576A2 (en) 2007-12-28 2008-12-08 Positive control cell pellets for immunohistochemistry and methods of use thereof
PCT/US2008/085841 WO2009085575A2 (en) 2007-12-28 2008-12-08 Calibrator quality control cell device for immunohistochemistry assay and methods of use thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2008/085833 WO2009085573A2 (en) 2007-12-28 2008-12-08 Quality control cell device for immunohistochemistry assay and methods of use thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/US2008/085841 WO2009085575A2 (en) 2007-12-28 2008-12-08 Calibrator quality control cell device for immunohistochemistry assay and methods of use thereof

Country Status (1)

Country Link
WO (3) WO2009085573A2 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR080513A1 (en) 2010-03-12 2012-04-11 Inmunogen Inc CD37 UNION MOLECULES AND THEIR IMMUNOCATE PLAYERS
JP6018622B2 (en) 2011-04-01 2016-11-02 イミュノジェン， インコーポレイテッド CD37 binding molecule and immune complex thereof
KR20140143810A (en) * 2012-03-30 2014-12-17 이뮤노젠 아이엔씨 Methods for increasing efficacy of cd37-based therapy
US20130338014A1 (en) * 2012-04-05 2013-12-19 Vala Sciences, Inc. Calibration Standards For Digital Histocytometry
US20130338016A1 (en) * 2012-04-17 2013-12-19 Vala Sciences, Inc. Method For Integrated Pathology Diagnosis And Digital Biomarker Pattern Analysis
WO2014052876A1 (en) * 2012-09-28 2014-04-03 Immunogen Inc. Methods for increasing efficacy of cd56- based therapy
WO2014165327A1 (en) 2013-03-30 2014-10-09 Clarient Diagnostic Services, Inc. Microscope slides with quality controls thereon
EP3027226A4 (en) * 2013-08-02 2016-07-27 Siemens Healthcare Diagnostics Cell-based control and method
WO2016200676A1 (en) 2015-06-08 2016-12-15 Immunogen, Inc. Anti-cd37 immunoconjugate and anti-cd20 antibody combinations
EA201890347A1 (en) 2015-08-28 2018-09-28 Дебиофарм Интернэшнл, С.А. ANTIBODIES AND RESEARCH FOR DETECTION CD37
CN105241726A (en) * 2015-09-14 2016-01-13 黄小军 Immunohistochemical staining method and applications of immunohistochemical staining method in cervical tumorous lesion screening
JP2020510608A (en) 2016-11-02 2020-04-09 デビオファーム インターナショナル， エス． アー． Method for improving anti-CD37 immunoconjugate therapy
EP3639031A4 (en) * 2017-06-15 2021-05-05 Sunstone Scientific Limited. Method for ihc antigen imaging scale extrapolation
JP2020523614A (en) * 2017-06-15 2020-08-06 サンストーン サイエンティフィック リミテッド Process recording slides for immunohistochemical staining
US10921223B2 (en) * 2018-10-12 2021-02-16 Shenzhen Prs Limited Process record slide for staining and method of using the same
GB202006257D0 (en) * 2020-04-28 2020-06-10 Leeds Teaching Hospitals Nhs Trust Stain assessment
CN113515077A (en) * 2021-04-23 2021-10-19 重庆德方信息技术有限公司 System and method for monitoring human body cell staining process
GB2606387A (en) * 2021-05-06 2022-11-09 Futamura Chemical Uk Ltd Device
CN117295946A (en) * 2021-06-07 2023-12-26 株式会社日立高新技术 Control slide for pathological examination and method for manufacturing same

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991005263A1 (en) * 1989-09-26 1991-04-18 City Of Hope Quantitative immunocytochemistry assay
US5846749A (en) * 1994-10-12 1998-12-08 The Regents Of The University Of California Quantitative measurement of tissue protein identified by immunohistochemistry and standardized protein determination
WO2000062064A2 (en) * 1999-04-14 2000-10-19 Cytologix Corporation Quality control for cytochemical assays
US20050003458A1 (en) * 2003-06-12 2005-01-06 Mathew Moore Method and system for the analysis of high density cells samples
US20070141723A1 (en) * 2005-12-16 2007-06-21 Sompuram Seshi A Immunohistochemistry staining controls

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100650162B1 (en) * 2003-08-05 2006-11-27 주식회사 진인 Microarray comprising probes for drug-resistant hepatitis B virus detection, quality control and negative control, and Method for detecting drug-resistant hepatitis B virus using the same

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991005263A1 (en) * 1989-09-26 1991-04-18 City Of Hope Quantitative immunocytochemistry assay
US5846749A (en) * 1994-10-12 1998-12-08 The Regents Of The University Of California Quantitative measurement of tissue protein identified by immunohistochemistry and standardized protein determination
WO2000062064A2 (en) * 1999-04-14 2000-10-19 Cytologix Corporation Quality control for cytochemical assays
US20050003458A1 (en) * 2003-06-12 2005-01-06 Mathew Moore Method and system for the analysis of high density cells samples
US20070141723A1 (en) * 2005-12-16 2007-06-21 Sompuram Seshi A Immunohistochemistry staining controls

Also Published As

Publication number Publication date
WO2009085575A2 (en) 2009-07-09
WO2009085573A2 (en) 2009-07-09
WO2009085573A3 (en) 2009-09-17
WO2009085575A3 (en) 2009-09-17
WO2009085576A2 (en) 2009-07-09

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