WO2009085575A3 - Calibrator quality control cell device for immunohistochemistry assay and methods of use thereof - Google Patents
Calibrator quality control cell device for immunohistochemistry assay and methods of use thereof Download PDFInfo
- Publication number
- WO2009085575A3 WO2009085575A3 PCT/US2008/085841 US2008085841W WO2009085575A3 WO 2009085575 A3 WO2009085575 A3 WO 2009085575A3 US 2008085841 W US2008085841 W US 2008085841W WO 2009085575 A3 WO2009085575 A3 WO 2009085575A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- calibrator
- quality control
- immunohistochemistry assay
- cell device
- Prior art date
Links
- 238000003364 immunohistochemistry Methods 0.000 title abstract 4
- 238000012308 immunohistochemistry method Methods 0.000 title abstract 2
- 238000003908 quality control method Methods 0.000 title abstract 2
- 238000011532 immunohistochemical staining Methods 0.000 abstract 2
- 239000008188 pellet Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 238000010186 staining Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/5436—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand physically entrapped within the solid phase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N1/312—Apparatus therefor for samples mounted on planar substrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides
Abstract
This disclosure relates to immunohistochemistry, and specifically to a quality control device for an immunohistochemistry assay and methods of use thereof. More specifically, disclosed herein is a calibrator cell pellet and methods of use as a control in an immunohistochemistry assay. The calibrator cell pellets are used, in some embodiments, as standards for quantifying the intensity of immunohistochemical staining, for instance for normalizing immunohistochemical staining to a calibrated standard, thereby allowing more accurate quantitation of staining intensity.
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US942607P | 2007-12-28 | 2007-12-28 | |
US942007P | 2007-12-28 | 2007-12-28 | |
US936007P | 2007-12-28 | 2007-12-28 | |
US61/009,426 | 2007-12-28 | ||
US61/009,360 | 2007-12-28 | ||
US61/009,420 | 2007-12-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009085575A2 WO2009085575A2 (en) | 2009-07-09 |
WO2009085575A3 true WO2009085575A3 (en) | 2009-09-17 |
Family
ID=40824978
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2008/085844 WO2009085576A2 (en) | 2007-12-28 | 2008-12-08 | Positive control cell pellets for immunohistochemistry and methods of use thereof |
PCT/US2008/085833 WO2009085573A2 (en) | 2007-12-28 | 2008-12-08 | Quality control cell device for immunohistochemistry assay and methods of use thereof |
PCT/US2008/085841 WO2009085575A2 (en) | 2007-12-28 | 2008-12-08 | Calibrator quality control cell device for immunohistochemistry assay and methods of use thereof |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2008/085844 WO2009085576A2 (en) | 2007-12-28 | 2008-12-08 | Positive control cell pellets for immunohistochemistry and methods of use thereof |
PCT/US2008/085833 WO2009085573A2 (en) | 2007-12-28 | 2008-12-08 | Quality control cell device for immunohistochemistry assay and methods of use thereof |
Country Status (1)
Country | Link |
---|---|
WO (3) | WO2009085576A2 (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL2544719T3 (en) | 2010-03-12 | 2020-01-31 | Debiopharm International S.A. | Cd37-binding molecules and immunoconjugates thereof |
AU2012236210B2 (en) | 2011-04-01 | 2016-02-04 | Immunogen, Inc. | CD37-binding molecules and immunoconjugates thereof |
WO2013149171A2 (en) * | 2012-03-30 | 2013-10-03 | Immunogen, Inc. | Methods for increasing efficacy of cd37-based therapy |
US20130338014A1 (en) * | 2012-04-05 | 2013-12-19 | Vala Sciences, Inc. | Calibration Standards For Digital Histocytometry |
US20130338016A1 (en) * | 2012-04-17 | 2013-12-19 | Vala Sciences, Inc. | Method For Integrated Pathology Diagnosis And Digital Biomarker Pattern Analysis |
WO2014052876A1 (en) * | 2012-09-28 | 2014-04-03 | Immunogen Inc. | Methods for increasing efficacy of cd56- based therapy |
WO2014165327A1 (en) | 2013-03-30 | 2014-10-09 | Clarient Diagnostic Services, Inc. | Microscope slides with quality controls thereon |
EP3027226A4 (en) * | 2013-08-02 | 2016-07-27 | Siemens Healthcare Diagnostics | Cell-based control and method |
EP3302561A4 (en) | 2015-06-08 | 2019-02-06 | Debiopharm International SA | Anti-cd37 immunoconjugate and anti-cd20 antibody combinations |
CA2995243A1 (en) | 2015-08-28 | 2017-03-09 | Debiopharm International, S.A. | Antibodies and assays for detection of cd37 |
CN105241726A (en) * | 2015-09-14 | 2016-01-13 | 黄小军 | Immunohistochemical staining method and applications of immunohistochemical staining method in cervical tumorous lesion screening |
EP3535297B1 (en) | 2016-11-02 | 2022-08-10 | Debiopharm International, S.A. | Methods for improving anti-cd37 immunoconjugate therapy |
WO2018228575A1 (en) * | 2017-06-15 | 2018-12-20 | Sunstone Scientific Limited. | Process record slide for immunohistochemical staining |
WO2018228577A1 (en) * | 2017-06-15 | 2018-12-20 | Sunstone Scientific Limited. | Method for ihc antigen imaging scale extrapolation |
US10921223B2 (en) * | 2018-10-12 | 2021-02-16 | Shenzhen Prs Limited | Process record slide for staining and method of using the same |
GB202006257D0 (en) * | 2020-04-28 | 2020-06-10 | Leeds Teaching Hospitals Nhs Trust | Stain assessment |
CN113515077A (en) * | 2021-04-23 | 2021-10-19 | 重庆德方信息技术有限公司 | System and method for monitoring human body cell staining process |
GB2606387A (en) * | 2021-05-06 | 2022-11-09 | Futamura Chemical Uk Ltd | Device |
WO2022259810A1 (en) * | 2021-06-07 | 2022-12-15 | 株式会社日立ハイテク | Control slide glass for pathological examination and method for manufacturing same |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991005263A1 (en) * | 1989-09-26 | 1991-04-18 | City Of Hope | Quantitative immunocytochemistry assay |
US5846749A (en) * | 1994-10-12 | 1998-12-08 | The Regents Of The University Of California | Quantitative measurement of tissue protein identified by immunohistochemistry and standardized protein determination |
WO2000062064A2 (en) * | 1999-04-14 | 2000-10-19 | Cytologix Corporation | Quality control for cytochemical assays |
US20050003458A1 (en) * | 2003-06-12 | 2005-01-06 | Mathew Moore | Method and system for the analysis of high density cells samples |
KR100650162B1 (en) * | 2003-08-05 | 2006-11-27 | 주식회사 진인 | Microarray comprising probes for drug-resistant hepatitis B virus detection, quality control and negative control, and Method for detecting drug-resistant hepatitis B virus using the same |
US20070141723A1 (en) * | 2005-12-16 | 2007-06-21 | Sompuram Seshi A | Immunohistochemistry staining controls |
-
2008
- 2008-12-08 WO PCT/US2008/085844 patent/WO2009085576A2/en active Application Filing
- 2008-12-08 WO PCT/US2008/085833 patent/WO2009085573A2/en active Application Filing
- 2008-12-08 WO PCT/US2008/085841 patent/WO2009085575A2/en active Application Filing
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991005263A1 (en) * | 1989-09-26 | 1991-04-18 | City Of Hope | Quantitative immunocytochemistry assay |
US5846749A (en) * | 1994-10-12 | 1998-12-08 | The Regents Of The University Of California | Quantitative measurement of tissue protein identified by immunohistochemistry and standardized protein determination |
WO2000062064A2 (en) * | 1999-04-14 | 2000-10-19 | Cytologix Corporation | Quality control for cytochemical assays |
US20050003458A1 (en) * | 2003-06-12 | 2005-01-06 | Mathew Moore | Method and system for the analysis of high density cells samples |
KR100650162B1 (en) * | 2003-08-05 | 2006-11-27 | 주식회사 진인 | Microarray comprising probes for drug-resistant hepatitis B virus detection, quality control and negative control, and Method for detecting drug-resistant hepatitis B virus using the same |
US20070141723A1 (en) * | 2005-12-16 | 2007-06-21 | Sompuram Seshi A | Immunohistochemistry staining controls |
Also Published As
Publication number | Publication date |
---|---|
WO2009085575A2 (en) | 2009-07-09 |
WO2009085573A3 (en) | 2009-09-17 |
WO2009085576A2 (en) | 2009-07-09 |
WO2009085573A2 (en) | 2009-07-09 |
WO2009085576A3 (en) | 2009-09-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2009085575A3 (en) | Calibrator quality control cell device for immunohistochemistry assay and methods of use thereof | |
WO2009075306A1 (en) | Luminescence measurement method and luminescence measurement system | |
WO2010074899A3 (en) | Gain control based masking | |
WO2010093999A3 (en) | Method and appratus for virtual desktop ota | |
WO2008045307A3 (en) | Emissive compositions with internal standard and related techniques | |
WO2008060694A3 (en) | System and/or method for determining sufficiency of pseudorange measurements | |
ATE504044T1 (en) | PARAMETRIC CALIBRATION PROCEDURE | |
BRPI0615900A2 (en) | enzyme pellets, use of an enzyme pellet, and ration | |
WO2007119111A3 (en) | Tissue diagnostics for ovarian cancer | |
WO2005098446A3 (en) | Biomarkers for ovarian cancer | |
WO2009129505A3 (en) | Compositions, methods, and kits using synthetic probes for determining the presence of a target nucleic acid | |
GB0620504D0 (en) | Method | |
WO2010096154A3 (en) | Compositions and methods for diagnosis and prognosis of colorectal cancer | |
WO2010014823A3 (en) | Dynamic iot setpoints and interference control | |
WO2012099446A3 (en) | Transparent ion sensor chip using a field-effect-transistor-type signal converter in which an extended gate electrode is formed, and method for manufacturing the sensor chip | |
WO2008079185A3 (en) | Pesticide biomarker | |
WO2008008878A3 (en) | Method for deriving consistent color measurements | |
WO2012054783A3 (en) | Internal focus reference beads for imaging cytometry | |
WO2008027988A3 (en) | Methods of treating estrogen-responsive conditions by orphan nuclear receptor activation | |
WO2012042228A3 (en) | Method and system for determining characteristics of an embryo and uses thereof | |
WO2007149809A3 (en) | Tacrolimus standard and methods of using same | |
WO2011156249A3 (en) | Yeast concentration and viability measurement | |
WO2007038756A3 (en) | Methods and constructs for analyzing biological activities of biological specimens and determining states of organism | |
WO2009051427A3 (en) | A kit for diagnosis of breast cancer using herceptin, a composition comprising herceptin and a method for detecting herceptin-sensitive her2 overexpressed cell using the same | |
WO2007002574A3 (en) | Cspcna isoform modifications and uses thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 08867375 Country of ref document: EP Kind code of ref document: A2 |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
122 | Ep: pct application non-entry in european phase |
Ref document number: 08867375 Country of ref document: EP Kind code of ref document: A2 |