WO2009085199A3 - Capping bioprosthetic tissue to reduce calcification - Google Patents
Capping bioprosthetic tissue to reduce calcification Download PDFInfo
- Publication number
- WO2009085199A3 WO2009085199A3 PCT/US2008/013879 US2008013879W WO2009085199A3 WO 2009085199 A3 WO2009085199 A3 WO 2009085199A3 US 2008013879 W US2008013879 W US 2008013879W WO 2009085199 A3 WO2009085199 A3 WO 2009085199A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- tissue
- calcification
- capping agent
- oxidation
- bioprosthetic tissue
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
- A61F2/2415—Manufacturing methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0095—Packages or dispensers for prostheses or other implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
- A61F2/2418—Scaffolds therefor, e.g. support stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3625—Vascular tissue, e.g. heart valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3629—Intestinal tissue, e.g. small intestinal submucosa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/02—Treatment of implants to prevent calcification or mineralisation in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/20—Materials or treatment for tissue regeneration for reconstruction of the heart, e.g. heart valves
Abstract
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP18197247.2A EP3453409B1 (en) | 2007-12-21 | 2008-12-19 | Capping bioprosthetic tissue to reduce calcification |
EP08866741.5A EP2234657B1 (en) | 2007-12-21 | 2008-12-19 | Capping bioprosthetic tissue to reduce calcification |
EP13003386.3A EP2647393B1 (en) | 2007-12-21 | 2008-12-19 | Capping bioprosthetic tissue to reduce calcification |
CA2710366A CA2710366C (en) | 2007-12-21 | 2008-12-19 | Capping bioprosthetic tissue to reduce calcification |
CN200880126930.4A CN101965205B (en) | 2007-12-21 | 2008-12-19 | Capping bioprosthetic tissue to reduce calcification |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1626307P | 2007-12-21 | 2007-12-21 | |
US61/016,263 | 2007-12-21 | ||
US12/338,872 US8357387B2 (en) | 2007-12-21 | 2008-12-18 | Capping bioprosthetic tissue to reduce calcification |
US12/338,872 | 2008-12-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009085199A2 WO2009085199A2 (en) | 2009-07-09 |
WO2009085199A3 true WO2009085199A3 (en) | 2009-12-17 |
Family
ID=40789552
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2008/013879 WO2009085199A2 (en) | 2007-12-21 | 2008-12-19 | Capping bioprosthetic tissue to reduce calcification |
Country Status (5)
Country | Link |
---|---|
US (7) | US8357387B2 (en) |
EP (3) | EP2234657B1 (en) |
CN (2) | CN103705980B (en) |
CA (1) | CA2710366C (en) |
WO (1) | WO2009085199A2 (en) |
Families Citing this family (191)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0850607A1 (en) | 1996-12-31 | 1998-07-01 | Cordis Corporation | Valve prosthesis for implantation in body channels |
US6454799B1 (en) | 2000-04-06 | 2002-09-24 | Edwards Lifesciences Corporation | Minimally-invasive heart valves and methods of use |
US7556646B2 (en) | 2001-09-13 | 2009-07-07 | Edwards Lifesciences Corporation | Methods and apparatuses for deploying minimally-invasive heart valves |
US6733525B2 (en) | 2001-03-23 | 2004-05-11 | Edwards Lifesciences Corporation | Rolled minimally-invasive heart valves and methods of use |
US6893460B2 (en) | 2001-10-11 | 2005-05-17 | Percutaneous Valve Technologies Inc. | Implantable prosthetic valve |
US8308797B2 (en) | 2002-01-04 | 2012-11-13 | Colibri Heart Valve, LLC | Percutaneously implantable replacement heart valve device and method of making same |
DE102005003632A1 (en) | 2005-01-20 | 2006-08-17 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Catheter for the transvascular implantation of heart valve prostheses |
US7780723B2 (en) | 2005-06-13 | 2010-08-24 | Edwards Lifesciences Corporation | Heart valve delivery system |
AU2006315812B2 (en) | 2005-11-10 | 2013-03-28 | Cardiaq Valve Technologies, Inc. | Balloon-expandable, self-expanding, vascular prosthesis connecting stent |
EP2077718B2 (en) * | 2006-10-27 | 2022-03-09 | Edwards Lifesciences Corporation | Biological tissue for surgical implantation |
US8236045B2 (en) | 2006-12-22 | 2012-08-07 | Edwards Lifesciences Corporation | Implantable prosthetic valve assembly and method of making the same |
US8105375B2 (en) * | 2007-01-19 | 2012-01-31 | The Cleveland Clinic Foundation | Method for implanting a cardiovascular valve |
US7896915B2 (en) | 2007-04-13 | 2011-03-01 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
US9101691B2 (en) | 2007-06-11 | 2015-08-11 | Edwards Lifesciences Corporation | Methods for pre-stressing and capping bioprosthetic tissue |
DE102007043830A1 (en) | 2007-09-13 | 2009-04-02 | Lozonschi, Lucian, Madison | Heart valve stent |
US8357387B2 (en) * | 2007-12-21 | 2013-01-22 | Edwards Lifesciences Corporation | Capping bioprosthetic tissue to reduce calcification |
US9044318B2 (en) | 2008-02-26 | 2015-06-02 | Jenavalve Technology Gmbh | Stent for the positioning and anchoring of a valvular prosthesis |
ES2903231T3 (en) | 2008-02-26 | 2022-03-31 | Jenavalve Tech Inc | Stent for positioning and anchoring a valve prosthesis at an implantation site in a patient's heart |
US8460368B2 (en) | 2008-02-29 | 2013-06-11 | Edwards Lifesciences Corporation | Expandable member for deploying a prosthetic device |
US20090276040A1 (en) | 2008-05-01 | 2009-11-05 | Edwards Lifesciences Corporation | Device and method for replacing mitral valve |
US8323335B2 (en) | 2008-06-20 | 2012-12-04 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic valves and methods for using |
US8652202B2 (en) | 2008-08-22 | 2014-02-18 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
CA2749026C (en) | 2008-09-29 | 2018-01-09 | Impala, Inc. | Heart valve |
EP2845569A1 (en) | 2008-10-01 | 2015-03-11 | Cardiaq Valve Technologies, Inc. | Delivery system for vascular implant |
US8690936B2 (en) | 2008-10-10 | 2014-04-08 | Edwards Lifesciences Corporation | Expandable sheath for introducing an endovascular delivery device into a body |
WO2010121076A2 (en) | 2009-04-15 | 2010-10-21 | Cardiaq Valve Technologies, Inc. | Vascular implant and delivery system |
US9730790B2 (en) | 2009-09-29 | 2017-08-15 | Edwards Lifesciences Cardiaq Llc | Replacement valve and method |
CN101721745B (en) * | 2009-11-09 | 2015-04-01 | 山东省千佛山医院 | Method for processing donkey pericardium for artificial heart valve and other biological repairing material |
US8449599B2 (en) | 2009-12-04 | 2013-05-28 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
EP2509538B1 (en) | 2009-12-08 | 2017-09-20 | Avalon Medical Ltd. | Device and system for transcatheter mitral valve replacement |
US8869982B2 (en) | 2009-12-18 | 2014-10-28 | Edwards Lifesciences Corporation | Prosthetic heart valve packaging and deployment system |
US8839957B2 (en) * | 2010-02-15 | 2014-09-23 | Michael C. Murad | Prosthetic heart valve packaging system |
AU2011223708A1 (en) * | 2010-03-01 | 2012-09-27 | Colibri Heart Valve Llc | Percutaneously deliverable heart valve and methods associated therewith |
AU2013204420B2 (en) * | 2010-03-01 | 2014-07-31 | Colibri Heart Valve Llc | Percutaneously deliverable heart valve and methods associated therewith |
US8679404B2 (en) | 2010-03-05 | 2014-03-25 | Edwards Lifesciences Corporation | Dry prosthetic heart valve packaging system |
NZ602066A (en) | 2010-03-23 | 2013-09-27 | Edwards Lifesciences Corp | Methods of conditioning sheet bioprosthetic tissue |
US8579964B2 (en) | 2010-05-05 | 2013-11-12 | Neovasc Inc. | Transcatheter mitral valve prosthesis |
JP2013526388A (en) | 2010-05-25 | 2013-06-24 | イエナバルブ テクノロジー インク | Artificial heart valve, and transcatheter delivery prosthesis comprising an artificial heart valve and a stent |
IT1400544B1 (en) * | 2010-06-09 | 2013-06-11 | Sorin Biomedica Cardio Srl | PROCESS OF DETOXIFICATION OF BIOLOGICAL FABRIC. |
IT1400545B1 (en) | 2010-06-09 | 2013-06-11 | Sorin Biomedica Cardio Srl | PROCEDURE FOR THE PREPARATION OF BIOLOGICAL FABRIC FOR BIOLOGICAL PROSTHESIS. |
US8906601B2 (en) | 2010-06-17 | 2014-12-09 | Edwardss Lifesciences Corporation | Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates |
CA2794135C (en) * | 2010-06-17 | 2018-01-02 | Edwards Lifesciences Corporation | Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates |
CN103153384B (en) | 2010-06-28 | 2016-03-09 | 科利柏心脏瓣膜有限责任公司 | For the device of device in the delivery of vascular of chamber |
EP2608815B1 (en) | 2010-08-24 | 2018-03-21 | Collagen Solutions NZ Limited | Biomaterials with enhanced properties and devices made therefrom |
EP2618784B1 (en) | 2010-09-23 | 2016-05-25 | Edwards Lifesciences CardiAQ LLC | Replacement heart valves and delivery devices |
US9351829B2 (en) | 2010-11-17 | 2016-05-31 | Edwards Lifesciences Corporation | Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability |
SG191008A1 (en) | 2010-12-14 | 2013-07-31 | Colibri Heart Valve Llc | Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets |
US9498317B2 (en) * | 2010-12-16 | 2016-11-22 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery systems and packaging |
CN102114270B (en) * | 2011-02-22 | 2013-08-07 | 上海微创医疗器械(集团)有限公司 | Gradient cross linking and modifying type durable prosthetic biological valve and preparation method thereof |
US9155619B2 (en) | 2011-02-25 | 2015-10-13 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery apparatus |
US9554897B2 (en) | 2011-04-28 | 2017-01-31 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
US9308087B2 (en) | 2011-04-28 | 2016-04-12 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
US8968394B2 (en) | 2011-05-12 | 2015-03-03 | Edwards Lifesciences Corporation | Mitral heart valve holder and storage system |
US9289282B2 (en) | 2011-05-31 | 2016-03-22 | Edwards Lifesciences Corporation | System and method for treating valve insufficiency or vessel dilatation |
KR101246721B1 (en) | 2011-06-13 | 2013-03-26 | 한국원자력연구원 | A combined irradiation method with polyglutamic acid for preventing the decrease in the physical and physiological properties of skin or tendon tissues and skin or tendon substitutes by sterilization |
WO2013009851A2 (en) * | 2011-07-11 | 2013-01-17 | The Children's Hospital Of Philadelphia | Oxidation resistant bioprosthetic tissues and preparation thereof |
US9119716B2 (en) | 2011-07-27 | 2015-09-01 | Edwards Lifesciences Corporation | Delivery systems for prosthetic heart valve |
CA3040390C (en) | 2011-08-11 | 2022-03-15 | Tendyne Holdings, Inc. | Improvements for prosthetic valves and related inventions |
FR2979534B1 (en) * | 2011-09-06 | 2013-12-27 | Protip | NEW INTRALARYNGEE PROSTHESIS |
FR2983060B1 (en) | 2011-11-30 | 2013-12-06 | Protip | MEDICAL SUPPORT DEVICE FOR IMPLANT OR PROSTHESIS |
CA2857997C (en) | 2011-12-09 | 2021-01-05 | Edwards Lifesciences Corporation | Prosthetic heart valve having improved commissure supports |
US9827092B2 (en) | 2011-12-16 | 2017-11-28 | Tendyne Holdings, Inc. | Tethers for prosthetic mitral valve |
CN104302329A (en) * | 2012-03-31 | 2015-01-21 | 学校法人早稻田大学 | Method for treating biological tissue and biological tissue |
US9345573B2 (en) | 2012-05-30 | 2016-05-24 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
US9301835B2 (en) | 2012-06-04 | 2016-04-05 | Edwards Lifesciences Corporation | Pre-assembled bioprosthetic valve and sealed conduit |
WO2014022124A1 (en) | 2012-07-28 | 2014-02-06 | Tendyne Holdings, Inc. | Improved multi-component designs for heart valve retrieval device, sealing structures and stent assembly |
WO2014021905A1 (en) | 2012-07-30 | 2014-02-06 | Tendyne Holdings, Inc. | Improved delivery systems and methods for transcatheter prosthetic valves |
US9693862B2 (en) | 2012-07-31 | 2017-07-04 | Edwards Lifesciences Corporation | Holders for prosthetic heart valves |
US9510946B2 (en) | 2012-09-06 | 2016-12-06 | Edwards Lifesciences Corporation | Heart valve sealing devices |
US9585748B2 (en) | 2012-09-25 | 2017-03-07 | Edwards Lifesciences Corporation | Methods for replacing a native heart valve and aorta with a prosthetic heart valve and conduit |
US10058630B2 (en) * | 2012-10-22 | 2018-08-28 | Concievalve, Llc | Methods for inhibiting stenosis, obstruction, or calcification of a stented heart valve or bioprosthesis |
US9844436B2 (en) | 2012-10-26 | 2017-12-19 | Edwards Lifesciences Corporation | Aortic valve and conduit graft implant tool |
US10238771B2 (en) | 2012-11-08 | 2019-03-26 | Edwards Lifesciences Corporation | Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system |
US9439763B2 (en) | 2013-02-04 | 2016-09-13 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
US9168129B2 (en) | 2013-02-12 | 2015-10-27 | Edwards Lifesciences Corporation | Artificial heart valve with scalloped frame design |
US10583002B2 (en) | 2013-03-11 | 2020-03-10 | Neovasc Tiara Inc. | Prosthetic valve with anti-pivoting mechanism |
US9730791B2 (en) | 2013-03-14 | 2017-08-15 | Edwards Lifesciences Cardiaq Llc | Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery |
US9681951B2 (en) | 2013-03-14 | 2017-06-20 | Edwards Lifesciences Cardiaq Llc | Prosthesis with outer skirt and anchors |
WO2014145811A1 (en) | 2013-03-15 | 2014-09-18 | Edwards Lifesciences Corporation | Valved aortic conduits |
US9486306B2 (en) | 2013-04-02 | 2016-11-08 | Tendyne Holdings, Inc. | Inflatable annular sealing device for prosthetic mitral valve |
US11224510B2 (en) | 2013-04-02 | 2022-01-18 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
US10463489B2 (en) | 2013-04-02 | 2019-11-05 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
US9572665B2 (en) | 2013-04-04 | 2017-02-21 | Neovasc Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
US10478293B2 (en) | 2013-04-04 | 2019-11-19 | Tendyne Holdings, Inc. | Retrieval and repositioning system for prosthetic heart valve |
TR201816620T4 (en) | 2013-05-20 | 2018-11-21 | Edwards Lifesciences Corp | Heart valve prosthesis delivery device. |
US9610159B2 (en) | 2013-05-30 | 2017-04-04 | Tendyne Holdings, Inc. | Structural members for prosthetic mitral valves |
CN105658178B (en) | 2013-06-25 | 2018-05-08 | 坦迪尼控股股份有限公司 | Feature is complied with thrombus management and structure for prosthetic heart valve |
CA2919379C (en) | 2013-08-01 | 2021-03-30 | Tendyne Holdings, Inc. | Epicardial anchor devices and methods |
JP6563394B2 (en) | 2013-08-30 | 2019-08-21 | イェーナヴァルヴ テクノロジー インコーポレイテッド | Radially foldable frame for an artificial valve and method for manufacturing the frame |
FR3009951B1 (en) | 2013-09-05 | 2017-01-20 | Protip | INTRA-LARYNGEAL PROSTHESIS |
US9615922B2 (en) | 2013-09-30 | 2017-04-11 | Edwards Lifesciences Corporation | Method and apparatus for preparing a contoured biological tissue |
US10959839B2 (en) | 2013-10-08 | 2021-03-30 | Edwards Lifesciences Corporation | Method for directing cellular migration patterns on a biological tissue |
WO2015058039A1 (en) | 2013-10-17 | 2015-04-23 | Robert Vidlund | Apparatus and methods for alignment and deployment of intracardiac devices |
JP6554094B2 (en) | 2013-10-28 | 2019-07-31 | テンダイン ホールディングス,インコーポレイテッド | Prosthetic heart valve and system and method for delivering an artificial heart valve |
US9526611B2 (en) | 2013-10-29 | 2016-12-27 | Tendyne Holdings, Inc. | Apparatus and methods for delivery of transcatheter prosthetic valves |
US20150122687A1 (en) | 2013-11-06 | 2015-05-07 | Edwards Lifesciences Corporation | Bioprosthetic heart valves having adaptive seals to minimize paravalvular leakage |
US9622863B2 (en) | 2013-11-22 | 2017-04-18 | Edwards Lifesciences Corporation | Aortic insufficiency repair device and method |
US10098734B2 (en) | 2013-12-05 | 2018-10-16 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
WO2015120122A2 (en) | 2014-02-05 | 2015-08-13 | Robert Vidlund | Apparatus and methods for transfemoral delivery of prosthetic mitral valve |
US9986993B2 (en) | 2014-02-11 | 2018-06-05 | Tendyne Holdings, Inc. | Adjustable tether and epicardial pad system for prosthetic heart valve |
USD755384S1 (en) | 2014-03-05 | 2016-05-03 | Edwards Lifesciences Cardiaq Llc | Stent |
CA2937566C (en) | 2014-03-10 | 2023-09-05 | Tendyne Holdings, Inc. | Devices and methods for positioning and monitoring tether load for prosthetic mitral valve |
US10195025B2 (en) | 2014-05-12 | 2019-02-05 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US9532870B2 (en) | 2014-06-06 | 2017-01-03 | Edwards Lifesciences Corporation | Prosthetic valve for replacing a mitral valve |
US10195026B2 (en) | 2014-07-22 | 2019-02-05 | Edwards Lifesciences Corporation | Mitral valve anchoring |
US10058424B2 (en) | 2014-08-21 | 2018-08-28 | Edwards Lifesciences Corporation | Dual-flange prosthetic valve frame |
JP6826035B2 (en) | 2015-01-07 | 2021-02-03 | テンダイン ホールディングス,インコーポレイテッド | Artificial mitral valve, and devices and methods for its delivery |
AU2016215197B2 (en) | 2015-02-05 | 2020-01-02 | Tendyne Holdings Inc. | Expandable epicardial pads and devices and methods for their delivery |
US10119882B2 (en) | 2015-03-10 | 2018-11-06 | Edwards Lifesciences Corporation | Surgical conduit leak testing |
EP4070763A1 (en) | 2015-04-16 | 2022-10-12 | Tendyne Holdings, Inc. | Apparatus for retrieval of transcathter prosthetic valves |
US10064718B2 (en) | 2015-04-16 | 2018-09-04 | Edwards Lifesciences Corporation | Low-profile prosthetic heart valve for replacing a mitral valve |
US10010417B2 (en) | 2015-04-16 | 2018-07-03 | Edwards Lifesciences Corporation | Low-profile prosthetic heart valve for replacing a mitral valve |
US10709555B2 (en) | 2015-05-01 | 2020-07-14 | Jenavalve Technology, Inc. | Device and method with reduced pacemaker rate in heart valve replacement |
CN106190949B (en) | 2015-05-08 | 2020-04-10 | 上海微创心通医疗科技有限公司 | Dry animal-derived collagen fiber tissue material, preparation method thereof and bioprosthesis |
CN104990882B (en) * | 2015-07-22 | 2018-05-01 | 杭州启明医疗器械有限公司 | The method and anticalcium factor solutions of external biological valve calcification evaluation |
US10350047B2 (en) | 2015-09-02 | 2019-07-16 | Edwards Lifesciences Corporation | Method and system for packaging and preparing a prosthetic heart valve and associated delivery system |
US10327894B2 (en) | 2015-09-18 | 2019-06-25 | Tendyne Holdings, Inc. | Methods for delivery of prosthetic mitral valves |
US10470876B2 (en) | 2015-11-10 | 2019-11-12 | Edwards Lifesciences Corporation | Transcatheter heart valve for replacing natural mitral valve |
US10376364B2 (en) | 2015-11-10 | 2019-08-13 | Edwards Lifesciences Corporation | Implant delivery capsule |
AU2016362474B2 (en) | 2015-12-03 | 2021-04-22 | Tendyne Holdings, Inc. | Frame features for prosthetic mitral valves |
US10357351B2 (en) | 2015-12-04 | 2019-07-23 | Edwards Lifesciences Corporation | Storage assembly for prosthetic valve |
AU2016380259B2 (en) | 2015-12-28 | 2020-10-22 | Tendyne Holdings, Inc. | Atrial pocket closures for prosthetic heart valves |
DE202017007326U1 (en) | 2016-01-29 | 2020-10-20 | Neovasc Tiara Inc. | Valve prosthesis to prevent flow obstruction |
US10470877B2 (en) | 2016-05-03 | 2019-11-12 | Tendyne Holdings, Inc. | Apparatus and methods for anterior valve leaflet management |
EP3454795B1 (en) | 2016-05-13 | 2023-01-11 | JenaValve Technology, Inc. | Heart valve prosthesis delivery system for delivery of heart valve prosthesis with introducer sheath and loading system |
EP3468480B1 (en) | 2016-06-13 | 2023-01-11 | Tendyne Holdings, Inc. | Sequential delivery of two-part prosthetic mitral valve |
EP3478224B1 (en) | 2016-06-30 | 2022-11-02 | Tendyne Holdings, Inc. | Prosthetic heart valves and apparatus for delivery of same |
EP3484411A1 (en) | 2016-07-12 | 2019-05-22 | Tendyne Holdings, Inc. | Apparatus and methods for trans-septal retrieval of prosthetic heart valves |
US10350062B2 (en) | 2016-07-21 | 2019-07-16 | Edwards Lifesciences Corporation | Replacement heart valve prosthesis |
CN109996581B (en) | 2016-11-21 | 2021-10-15 | 内奥瓦斯克迪亚拉公司 | Methods and systems for rapid retrieval of transcatheter heart valve delivery systems |
JP7094965B2 (en) | 2017-01-27 | 2022-07-04 | イエナバルブ テクノロジー インク | Heart valve imitation |
EP3366324A1 (en) * | 2017-02-22 | 2018-08-29 | Epygon | Product and method for the treatment of bioprosthetic tissues |
CN106913909B (en) * | 2017-02-27 | 2020-09-01 | 杭州启明医疗器械股份有限公司 | Dry artificial biological valve and preparation method thereof |
CN107007887B (en) * | 2017-02-27 | 2020-10-02 | 杭州启明医疗器械股份有限公司 | Cross-linked artificial biological valve and preparation method thereof |
US10631968B2 (en) | 2017-03-06 | 2020-04-28 | Edwards Lifesciences Corporation | Humidity-management packaging systems and methods |
CN110678590B (en) | 2017-05-31 | 2022-07-19 | 爱德华兹生命科学公司 | Collagen fibers and articles formed therefrom |
CN109125810A (en) * | 2017-06-19 | 2019-01-04 | 上海微创心通医疗科技有限公司 | A kind of preparation method of biovalve |
EP4344679A2 (en) | 2017-06-29 | 2024-04-03 | St. Jude Medical, Cardiology Division, Inc. | Method of preparing calcification-resistant bioprosthetic tissue |
WO2019014473A1 (en) | 2017-07-13 | 2019-01-17 | Tendyne Holdings, Inc. | Prosthetic heart valves and apparatus and methods for delivery of same |
CN111263622A (en) | 2017-08-25 | 2020-06-09 | 内奥瓦斯克迪亚拉公司 | Sequentially deployed transcatheter mitral valve prosthesis |
WO2019046099A1 (en) | 2017-08-28 | 2019-03-07 | Tendyne Holdings, Inc. | Prosthetic heart valves with tether coupling features |
WO2019051476A1 (en) | 2017-09-11 | 2019-03-14 | Incubar, LLC | Conduit vascular implant sealing device for reducing endoleak |
CA3075819A1 (en) | 2017-10-13 | 2019-04-18 | Edwards Lifesciences Corporation | Method for sterilizing heart valves |
WO2019147846A2 (en) | 2018-01-25 | 2019-08-01 | Edwards Lifesciences Corporation | Delivery system for aided replacement valve recapture and repositioning post- deployment |
DK3787561T3 (en) | 2018-04-30 | 2022-05-30 | Edwards Lifesciences Corp | Devices for shrinking prosthetic implants |
CN109260517B (en) * | 2018-09-19 | 2020-10-30 | 杭州启明医疗器械股份有限公司 | Prefillable dry biological heart valve and preparation method thereof |
CN109172867B (en) * | 2018-09-19 | 2020-12-01 | 杭州启明医疗器械股份有限公司 | Pre-assembled biological heart valve capable of being rapidly rehydrated and preparation method thereof |
CN109820625A (en) * | 2018-09-30 | 2019-05-31 | 四川大学 | A kind of artificial bio-prosthetic valve membrane processing method of crosslinking |
WO2020092205A1 (en) | 2018-11-01 | 2020-05-07 | Edwards Lifesciences Corporation | Transcatheter pulmonic regenerative valve |
EP3876870B1 (en) | 2018-11-08 | 2023-12-20 | Neovasc Tiara Inc. | Ventricular deployment of a transcatheter mitral valve prosthesis |
JP7438236B2 (en) | 2019-04-01 | 2024-02-26 | ニオバスク ティアラ インコーポレイテッド | Controllably deployable prosthetic valve |
CA3136334A1 (en) | 2019-04-10 | 2020-10-15 | Neovasc Tiara Inc. | Prosthetic valve with natural blood flow |
AU2020279750B2 (en) | 2019-05-20 | 2023-07-13 | Neovasc Tiara Inc. | Introducer with hemostasis mechanism |
CN110152064B (en) * | 2019-06-04 | 2020-09-08 | 四川大学 | Heart valve modified by hydrophilic composite network lamination and preparation method thereof |
AU2020295566B2 (en) | 2019-06-20 | 2023-07-20 | Neovasc Tiara Inc. | Low profile prosthetic mitral valve |
CN110507856A (en) * | 2019-09-29 | 2019-11-29 | 四川大学 | A kind of full prepackage is dry to intervene aorta petal membrane material and preparation method thereof |
AU2020363380A1 (en) | 2019-10-07 | 2021-12-16 | Edwards Lifesciences Corporation | Balloons for prosthetic valve delivery apparatus and methods of assembly |
CN110585492B (en) * | 2019-10-12 | 2022-01-25 | 上海微创医疗器械(集团)有限公司 | Medical material and method for preparing anticoagulant coating on surface of medical material |
CN114555012A (en) | 2019-10-31 | 2022-05-27 | 爱德华兹生命科学公司 | Blow-molded balloon shoulder assembly for transcatheter delivery device |
US11648110B2 (en) | 2019-12-05 | 2023-05-16 | Tendyne Holdings, Inc. | Braided anchor for mitral valve |
CN110917398A (en) * | 2019-12-09 | 2020-03-27 | 沛嘉医疗科技(苏州)有限公司 | Method for oxidation resistance of biomaterial and biomaterial |
AU2020399770A1 (en) * | 2019-12-09 | 2022-01-06 | Edwards Lifesciences Corporation | Bioprosthetic tissue preparation |
CN110917399A (en) * | 2019-12-09 | 2020-03-27 | 沛嘉医疗科技(苏州)有限公司 | Anti-calcification method for biomaterial and biomaterial |
CA3143300A1 (en) * | 2019-12-12 | 2021-06-17 | Edwards Lifesciences Corporation | Hybrid annuloplasty ring |
US11648114B2 (en) | 2019-12-20 | 2023-05-16 | Tendyne Holdings, Inc. | Distally loaded sheath and loading funnel |
CN111569152A (en) * | 2020-05-28 | 2020-08-25 | 四川大学 | Biological valve with anticoagulation and calcification resistance and preparation method thereof |
CN111420120A (en) * | 2020-05-28 | 2020-07-17 | 四川大学 | Biological valve with anticoagulation and anti-calcification functions and preparation method thereof |
CN111658824B (en) * | 2020-06-15 | 2021-03-30 | 四川大学 | Valve membrane material with synergistic anticoagulation and anti-calcification functions and preparation method thereof |
CN111658825B (en) * | 2020-06-15 | 2021-03-30 | 四川大学 | Valve material with long-acting antithrombotic performance and preparation method thereof |
CN111701077B (en) * | 2020-06-24 | 2021-05-11 | 四川大学 | Valve with antithrombotic and anticalcification functions and preparation method and application thereof |
CN111701079A (en) * | 2020-06-24 | 2020-09-25 | 四川大学 | Biological valve and treatment method thereof |
US11678980B2 (en) | 2020-08-19 | 2023-06-20 | Tendyne Holdings, Inc. | Fully-transseptal apical pad with pulley for tensioning |
EP4247297A1 (en) | 2020-12-18 | 2023-09-27 | Edwards Lifesciences Corporation | Storage jar assembly for aprosthetic heart valve |
CN114652893A (en) * | 2020-12-23 | 2022-06-24 | 上海微创心通医疗科技有限公司 | Method for treating bioprosthetic tissue and bioprosthetic heart valve |
CN114681673B (en) * | 2020-12-31 | 2023-05-23 | 杭州启明医疗器械股份有限公司 | Crease-resistant dehydrated crosslinking biological material and preparation method and application thereof |
WO2022260979A1 (en) | 2021-06-07 | 2022-12-15 | Edwards Lifesciences Corporation | Leaflets and leaflet separators for prosthetic valves |
CN115475031A (en) | 2021-06-15 | 2022-12-16 | 爱德华兹生命科学公司 | Prosthetic valve assembly |
CN113786515B (en) * | 2021-08-17 | 2022-10-11 | 中南大学湘雅二医院 | Method for treating cross-linked biological tissue |
IT202100025796A1 (en) * | 2021-10-08 | 2023-04-08 | Biocompatibility Innovation Srl | METHOD FOR THE PREPARATION OF SURFACES, IN PARTICULAR OF HEART PROSTHESES |
AU2022360405A1 (en) * | 2021-10-06 | 2024-03-14 | Biocompatibility Innovation S.r.l. | A method for the preparation of surfaces, particularly of cardiac prosthesis |
WO2023086650A1 (en) | 2021-11-15 | 2023-05-19 | Edwards Lifesciences Corporation | Prosthetic valves with wider outflow cells |
CN114748695B (en) * | 2021-11-17 | 2022-12-23 | 四川大学 | Method for improving calcification and anticoagulation of biological valve material by double-bond post-crosslinking |
WO2023183441A1 (en) | 2022-03-23 | 2023-09-28 | Edwards Lifesciences Corporation | Prosthetic valves with valvular structures retained between two frames |
CN220158478U (en) | 2022-04-07 | 2023-12-12 | 爱德华兹生命科学公司 | Packaging assembly for storing prosthetic heart valves |
WO2023249885A1 (en) | 2022-06-23 | 2023-12-28 | Edwards Lifesciences Corporation | Prosthetic valves with information indicators |
WO2023249884A1 (en) | 2022-06-24 | 2023-12-28 | Edwards Lifesciences Corporation | Prosthetic valves with support arms |
WO2024006230A1 (en) | 2022-06-27 | 2024-01-04 | Edwards Lifesciences Corporation | Leaflet perforation tools and associated methods |
CN117339019A (en) * | 2022-06-28 | 2024-01-05 | 江苏臻亿医疗科技有限公司 | Biological tissue treatment method and medical material |
WO2024025897A1 (en) | 2022-07-27 | 2024-02-01 | Edwards Lifesciences Corporation | Balloon assemblies with inflatable toroid balloons |
WO2024030290A1 (en) | 2022-08-01 | 2024-02-08 | Edwards Lifesciences Corporation | Inflatable balloons with flow channels |
WO2024050043A1 (en) | 2022-09-02 | 2024-03-07 | Edwards Lifesciences Corporation | Prosthetic valves with non-uniform valvular structures |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000032252A1 (en) * | 1998-11-27 | 2000-06-08 | University Of Sheffield | Skin composites |
US20030135284A1 (en) * | 1998-06-30 | 2003-07-17 | Katrina Crouch | Plasticized bone grafts and methods of making and using same |
US20060159641A1 (en) * | 2002-01-25 | 2006-07-20 | Biomedical Design, Inc. | Variably crosslinked tissue |
US20060217805A1 (en) * | 2005-03-25 | 2006-09-28 | Dove Jeffrey S | Treatment of bioprosthetic tissues to mitigate post implantation calcification |
Family Cites Families (268)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2567929A (en) | 1951-09-18 | Process for preserving plant tissues | ||
US6789191B1 (en) | 1999-05-25 | 2004-09-07 | Silverbrook Research Pty Ltd | Interactive device network registration protocol |
US2393580A (en) | 1942-03-31 | 1946-01-22 | Edwin C Weiskopf | Method of preparing tissue |
US2484813A (en) | 1945-06-06 | 1949-10-18 | John O Bower | Spun suture |
US3982587A (en) * | 1974-11-20 | 1976-09-28 | Stewart-Warner Corporation | Vehicular radiator assembly |
IL47062A (en) | 1975-04-10 | 1979-07-25 | Yeda Res & Dev | Process for diminishing antigenicity of tissues to be usedas transplants by treatment with glutaraldehyde |
US4067091A (en) * | 1976-11-15 | 1978-01-10 | Backman Philip E | Method of preparing human remains for storage |
US4120991A (en) | 1976-12-10 | 1978-10-17 | Technicon Instruments Corporation | Process for mounting tissue sections with an U.V. light curable mounting medium |
US4205059A (en) | 1977-03-09 | 1980-05-27 | Hagens Gunther Von | Animal and vegetal tissues permanently preserved by synthetic resin impregnation |
CA1087101A (en) * | 1977-08-05 | 1980-10-07 | Cesar Romero-Sierra | Freeze dried biological specimens |
US4197658A (en) * | 1978-05-12 | 1980-04-15 | Fts Systems, Inc. | Tissue freeze dryer |
US4328256A (en) * | 1978-08-18 | 1982-05-04 | Queen's University At Kingston | Preservation of green plant tissues |
DE2914181C2 (en) | 1979-04-07 | 1982-06-16 | Kernforschungsanlage Jülich GmbH, 5170 Jülich | Method and device for drying temperature-sensitive goods in the pharmaceutical and food industries |
US4294753A (en) | 1980-08-04 | 1981-10-13 | The Regents Of The University Of California | Bone morphogenetic protein process |
US4378224A (en) * | 1980-09-19 | 1983-03-29 | Nimni Marcel E | Coating for bioprosthetic device and method of making same |
US4323358A (en) * | 1981-04-30 | 1982-04-06 | Vascor, Inc. | Method for inhibiting mineralization of natural tissue during implantation |
US4372743A (en) | 1981-06-22 | 1983-02-08 | American Hospital Supply Corp. | Low-pressure fixation of valvular tissue intended for implantation |
US4350492A (en) | 1981-08-24 | 1982-09-21 | Vascor, Inc. | Method for preparing tissue heart valve |
FR2523810B1 (en) * | 1982-03-23 | 1988-11-25 | Carpentier Alain | ORGANIC GRAFT FABRIC AND PROCESS FOR ITS PREPARATION |
US4481009A (en) | 1982-05-13 | 1984-11-06 | American Hospital Supply Corporation | Polymer incorporation into implantable biological tissue to inhibit calcification |
US4402697A (en) | 1982-08-25 | 1983-09-06 | Extracorporeal Medical Specialties, Inc. | Method for inhibiting mineralization of natural tissue during implantation |
US4405327A (en) | 1982-08-25 | 1983-09-20 | Extracorporeal Medical Specialties, Inc. | Method for inhibiting mineralization of natural tissue during implantation |
JPS60500014A (en) | 1982-11-12 | 1985-01-10 | バツクスター トラベノル ラボラトリーズ インコーポレーテツド | Chemical sterilization of biological tissue ready for transplantation |
US5215541A (en) * | 1982-11-12 | 1993-06-01 | Baxter International Inc. | Surfactant treatment of implantable biological tissue to inhibit calcification |
US4885005A (en) | 1982-11-12 | 1989-12-05 | Baxter International Inc. | Surfactant treatment of implantable biological tissue to inhibit calcification |
US4599084A (en) * | 1983-05-24 | 1986-07-08 | American Hospital Supply Corp. | Method of using biological tissue to promote even bone growth |
IT1159433B (en) | 1983-07-25 | 1987-02-25 | Sorin Biomedica Spa | PROCEDURE AND EQUIPMENT FOR THE MANUFACTURE OF VALVE FLAPS FOR CARDIAC VALVE PROSTHESIS AND CARDIAC VALVE PROSTHESIS PROVIDED WITH SUCH FLAPS |
IL69333A (en) * | 1983-07-26 | 1986-04-29 | Biolog Ind | Process for plant tissue culture propagation |
US4865871A (en) | 1983-08-23 | 1989-09-12 | Board Of Regents The University Of Texas System | Method for cryopreparing biological tissue |
US5024830A (en) | 1983-08-23 | 1991-06-18 | The Board Of Regents, The University Of Texas | Method for cryopreparing biological tissue for ultrastructural analysis |
US4676070A (en) * | 1984-11-30 | 1987-06-30 | The Board Of Regents, The University Of Texas | Apparatus and method for cryopreparing biological tissue |
US4753652A (en) * | 1984-05-04 | 1988-06-28 | Children's Medical Center Corporation | Biomaterial implants which resist calcification |
GB8413319D0 (en) * | 1984-05-24 | 1984-06-27 | Oliver Roy Frederick | Biological material |
EP0169259A1 (en) | 1984-07-25 | 1986-01-29 | Surgical Patent Products Inc. Ltd. | Vascular prostheses for dry preservation, method of conditioning and their use in surgery |
US4553974A (en) | 1984-08-14 | 1985-11-19 | Mayo Foundation | Treatment of collagenous tissue with glutaraldehyde and aminodiphosphonate calcification inhibitor |
IT1180531B (en) * | 1984-09-21 | 1987-09-23 | Ge Sv In Srl | BICUSPID HEART VALVE PROSTHESIS |
US5011913A (en) * | 1985-06-28 | 1991-04-30 | The Procter & Gamble Company | Diphosphonate-derivatized macromolecules |
DE229810T1 (en) * | 1985-07-09 | 1987-11-05 | Quadrant Bioresources Ltd., Soulbury, Leighton Buzzard, Bedfordshire, Gb | PROTECTION OF PROTEINS AND SIMILAR. |
US4755593A (en) * | 1985-07-24 | 1988-07-05 | Lauren Mark D | Novel biomaterial of cross-linked peritoneal tissue |
US4770665A (en) | 1985-11-05 | 1988-09-13 | American Hospital Supply Corporation | Elastomeric polymer incorporation into implantable biological tissue to inhibit calcification |
US4729139A (en) * | 1985-11-05 | 1988-03-08 | Baxter Travenol | Selective incorporation of a polymer into implantable biological tissue to inhibit calcification |
DE3541478A1 (en) * | 1985-11-23 | 1987-05-27 | Beiersdorf Ag | HEART VALVE PROSTHESIS AND METHOD FOR THE PRODUCTION THEREOF |
US5904718A (en) * | 1986-03-27 | 1999-05-18 | Biocoll Laboratories, Inc. | Delayed drug delivery system |
US5108923A (en) * | 1986-04-25 | 1992-04-28 | Collaborative Research, Inc. | Bioadhesives for cell and tissue adhesion |
SE455268B (en) | 1986-05-23 | 1988-07-04 | Moelnlycke Ab | Needle PARTY TAPE |
GB8618374D0 (en) | 1986-07-28 | 1986-09-03 | Hsc Res Dev Corp | Biological vascular prostheses |
US4786287A (en) | 1986-10-10 | 1988-11-22 | Baxter Travenol Laboratories | Process for decreasing residual aldehyde levels in implantable bioprosthetic tissue |
US5044165A (en) | 1986-12-03 | 1991-09-03 | Board Of Regents, The University Of Texas | Cryo-slammer |
US4838888A (en) * | 1987-04-17 | 1989-06-13 | Baxter Travenol Laboratories, Inc. | Calcification mitigation of implantable bioprostheses |
FR2617855B1 (en) | 1987-07-08 | 1992-02-21 | Bioetica Sa | PROCESS FOR CROSSLINKING COLLAGEN BY INTRODUCING AZID GROUPS AS WELL AS TISSUES AND BIOMATERIALS OBTAINED BY IMPLEMENTING THE PROCESS |
US5147514A (en) | 1987-08-02 | 1992-09-15 | University Of North Carolina | Process for cross-linking collagenous material and resulting product |
US5149621A (en) | 1987-08-21 | 1992-09-22 | Cryolife, Inc. & Medical Univ. Of South Carolina | Kit for cryopreserving blood vessels |
JP2529112B2 (en) * | 1987-08-31 | 1996-08-28 | 株式会社 高研 | Biological valve |
US4994237A (en) * | 1987-10-02 | 1991-02-19 | The Beth Israel Hospital Association | Microwave preservation of bioprostheses |
GB8801338D0 (en) | 1988-01-21 | 1988-02-17 | Quadrant Bioresources Ltd | Preservation of viruses |
US4976733A (en) | 1988-02-03 | 1990-12-11 | Biomedical Design, Inc. | Prevention of prosthesis calcification |
US5368608A (en) | 1988-04-01 | 1994-11-29 | University Of Michigan, The Board Of Regents | Calcification-resistant materials and methods of making same through use of multivalent cations |
US5094661A (en) * | 1988-04-01 | 1992-03-10 | The University Of Michigan | Calcification-resistant materials and methods of making same through use of trivalent aluminum |
US5746775A (en) * | 1988-04-01 | 1998-05-05 | The Board Of Regent6S Of The University Of Michigan | Method of making calcification-resistant bioprosthetic tissue |
US4975526A (en) | 1989-02-23 | 1990-12-04 | Creative Biomolecules, Inc. | Bone collagen matrix for zenogenic implants |
US4994030A (en) * | 1988-06-28 | 1991-02-19 | Osteotech, Inc. | Reconstitution of human bone and tissue |
DE3834545A1 (en) | 1988-10-11 | 1990-04-12 | Rau Guenter | FLEXIBLE LOCKING ORGAN, PARTICULARLY HEART VALVE, AND METHOD FOR PRODUCING THE SAME |
US5002566A (en) * | 1989-02-17 | 1991-03-26 | Baxter International Inc. | Calcification mitigation of bioprosthetic implants |
US5068100A (en) | 1989-03-09 | 1991-11-26 | The Procter & Gamble Company | Anticalculus compositions |
US5051401A (en) | 1989-04-07 | 1991-09-24 | University Of South Alabama | Inhibition of mineral deposition by phosphorylated and related polyanionic peptides |
AU626686B2 (en) | 1989-06-09 | 1992-08-06 | Medtronic, Inc. | Dynamic fixation of porcine aortic valves |
CA2022480C (en) * | 1989-08-02 | 2001-02-27 | Gerald L. Mechanic | Process for cross-linking collagenous materials and resulting product |
US5154007A (en) | 1989-08-17 | 1992-10-13 | Board Of Regents University Of Texas System | Method and apparatus for cryopreparing biological tissue |
US5290558A (en) * | 1989-09-21 | 1994-03-01 | Osteotech, Inc. | Flowable demineralized bone powder composition and its use in bone repair |
AU7998091A (en) | 1990-05-17 | 1991-12-10 | Harbor Medical Devices, Inc. | Medical device polymer |
US8067149B2 (en) * | 1990-09-12 | 2011-11-29 | Lifecell Corporation | Acellular dermal matrix and method of use thereof for grafting |
US5336616A (en) | 1990-09-12 | 1994-08-09 | Lifecell Corporation | Method for processing and preserving collagen-based tissues for transplantation |
US5200399A (en) * | 1990-09-14 | 1993-04-06 | Boyce Thompson Institute For Plant Research, Inc. | Method of protecting biological materials from destructive reactions in the dry state |
US5104405A (en) * | 1991-02-21 | 1992-04-14 | The University Of Southern California | Process for improving the biostability of tissue implant devices and bioprosthetic implants so produced |
IT1245750B (en) | 1991-05-24 | 1994-10-14 | Sorin Biomedica Emodialisi S R | CARDIAC VALVE PROSTHESIS, PARTICULARLY FOR REPLACING THE AORTIC VALVE |
US5329846A (en) | 1991-08-12 | 1994-07-19 | Bonutti Peter M | Tissue press and system |
US6503277B2 (en) | 1991-08-12 | 2003-01-07 | Peter M. Bonutti | Method of transplanting human body tissue |
US5998483A (en) | 1991-09-20 | 1999-12-07 | Camiener; Gerald W. | Glyoxal-containing preservative compositions |
US5476516A (en) | 1992-03-13 | 1995-12-19 | Albert Einstein College Of Medicine Of Yeshiva University | Anticalcification treatment for aldehyde-tanned biological tissue |
US5257662A (en) * | 1992-03-27 | 1993-11-02 | The Allen Group Inc. | Heat exchanger assembly |
US5436291A (en) * | 1992-07-09 | 1995-07-25 | University Of Michigan, The Board Of . . . | Calcification-resistant synthetic biomaterials |
US5296583A (en) * | 1992-07-09 | 1994-03-22 | University Of Michigan | Calcification-resistant synthetic biomaterials |
US5437287A (en) | 1992-08-17 | 1995-08-01 | Carbomedics, Inc. | Sterilization of tissue implants using iodine |
US5522893A (en) | 1993-03-12 | 1996-06-04 | American Dental Association Health Foundation | Calcium phosphate hydroxyapatite precursor and methods for making and using the same |
US5509932A (en) * | 1993-04-08 | 1996-04-23 | Keogh; James R. | Fixed tissue medical devices comprising albumin-binding dyes |
US5507813A (en) * | 1993-12-09 | 1996-04-16 | Osteotech, Inc. | Shaped materials derived from elongate bone particles |
US5460962A (en) | 1994-01-04 | 1995-10-24 | Organogenesis Inc. | Peracetic acid sterilization of collagen or collagenous tissue |
DE59408037D1 (en) * | 1994-01-18 | 1999-05-06 | Sci Can | Arrangement for steam sterilization of medical instruments, implants and the like |
US5447536A (en) | 1994-02-17 | 1995-09-05 | Biomedical Design, Inc. | Method for fixation of biological tissue |
US6203755B1 (en) * | 1994-03-04 | 2001-03-20 | St. Jude Medical, Inc. | Electron beam sterilization of biological tissues |
DK0871414T3 (en) * | 1994-03-14 | 2004-08-30 | Cryolife Inc | Methods for preparing tissue for implantation |
US5595571A (en) | 1994-04-18 | 1997-01-21 | Hancock Jaffe Laboratories | Biological material pre-fixation treatment |
EP0757562A1 (en) * | 1994-04-29 | 1997-02-12 | W.L. Gore & Associates, Inc. | Improved blood contact surfaces using endothelium on a subendothelial extracellular matrix |
EP0757564A1 (en) | 1994-04-29 | 1997-02-12 | Gore Hybrid Technologies, Inc. | Improved blood contact surfaces employing natural subendothelial matrix and method for making and using the same |
US5558875A (en) | 1994-06-06 | 1996-09-24 | Wang; Su | Method of preparing collagenous tissue |
WO1995034332A1 (en) | 1994-06-15 | 1995-12-21 | St. Jude Medical, Inc. | Enhanced cross-linking of natural tissues |
DE4422555C1 (en) | 1994-06-28 | 1995-08-10 | Daimler Benz Ag | Rack=and=pinion steering with servomotor support |
KR0131046B1 (en) | 1994-07-13 | 1998-04-14 | 김은영 | Calcification-resistant tissue heart valve |
US5554184A (en) * | 1994-07-27 | 1996-09-10 | Machiraju; Venkat R. | Heart valve |
US5931969A (en) * | 1994-07-29 | 1999-08-03 | Baxter International Inc. | Methods and apparatuses for treating biological tissue to mitigate calcification |
CA2196165C (en) * | 1994-07-29 | 2004-06-08 | Sophie Carpentier | Methods for treating implantable biological tissues to mitigate the calcification thereof and bioprosthetic articles treated by such methods |
USRE40570E1 (en) | 1994-07-29 | 2008-11-11 | Edwards Lifesciences Corporation | Apparatuses and methods for treating biological tissue to mitigate calcification |
US6586006B2 (en) | 1994-08-04 | 2003-07-01 | Elan Drug Delivery Limited | Solid delivery systems for controlled release of molecules incorporated therein and methods of making same |
US6290991B1 (en) | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
US5556379A (en) | 1994-08-19 | 1996-09-17 | Lifenet Research Foundation | Process for cleaning large bone grafts and bone grafts produced thereby |
US5549666A (en) * | 1994-09-02 | 1996-08-27 | Baxter International Inc. | Natural tissue valve prostheses having variably complaint leaflets |
US5674298A (en) | 1994-10-21 | 1997-10-07 | The Board Of Regents Of The University Of Michigan | Calcification-resistant bioprosthetic tissue and methods of making same |
US6372228B1 (en) * | 1994-11-15 | 2002-04-16 | Kenton W. Gregory | Method of producing elastin, elastin-based biomaterials and tropoelastin materials |
AU692330B2 (en) * | 1994-12-30 | 1998-06-04 | National University Of Singapore, The | Method for reducing calcification of biological tissue used in implantable bioprostheses |
EP0821573A4 (en) * | 1995-04-19 | 2000-08-09 | St Jude Medical | Matrix substrate for a viable body tissue-derived prosthesis and method for making the same |
US6231608B1 (en) * | 1995-06-07 | 2001-05-15 | Crosscart, Inc. | Aldehyde and glycosidase-treated soft and bone tissue xenografts |
US5865849A (en) | 1995-06-07 | 1999-02-02 | Crosscart, Inc. | Meniscal heterografts |
US5913900A (en) * | 1995-06-07 | 1999-06-22 | Corsscart, Inc. | Substantially native meniscal cartilage heterografts |
US6685940B2 (en) * | 1995-07-27 | 2004-02-03 | Genentech, Inc. | Protein formulation |
US5782915A (en) | 1995-09-15 | 1998-07-21 | Stone; Kevin R. | Articular cartilage heterografts |
US5902338A (en) * | 1995-09-15 | 1999-05-11 | Crosscart, Inc. | Anterior cruciate ligament heterograft |
US5720894A (en) | 1996-01-11 | 1998-02-24 | The Regents Of The University Of California | Ultrashort pulse high repetition rate laser system for biological tissue processing |
US6193749B1 (en) * | 1996-02-05 | 2001-02-27 | St. Jude Medical, Inc. | Calcification-resistant biomaterials |
US6302909B1 (en) | 1996-07-31 | 2001-10-16 | St. Jude Medical, Inc. | Calcification-resistant biomaterials |
IT1285308B1 (en) * | 1996-03-12 | 1998-06-03 | Sorin Biomedica Cardio Spa | PROCEDURE FOR THE PREPARATION OF BIOLOGICAL MATERIAL FOR PLANT |
US5919472A (en) | 1996-03-19 | 1999-07-06 | Medtronic, Inc. | Treatment of aldehyde-fixed tissue |
US6024735A (en) * | 1996-03-20 | 2000-02-15 | Lifenet Research Foundation | Process and composition for cleaning soft tissue grafts optionally attached to bone and soft tissue and bone grafts produced thereby |
US5945319A (en) | 1996-04-25 | 1999-08-31 | Medtronic, Inc. | Periodate oxidative method for attachment of biomolecules to medical device surfaces |
US5928916A (en) | 1996-04-25 | 1999-07-27 | Medtronic, Inc. | Ionic attachment of biomolecules with a guanidino moiety to medical device surfaces |
US5925552A (en) | 1996-04-25 | 1999-07-20 | Medtronic, Inc. | Method for attachment of biomolecules to medical devices surfaces |
IL118149A0 (en) | 1996-05-05 | 1996-09-12 | Rdc Rafael Dev Corp | Method for producing heart valves and heart valves produced by the method |
US5766520A (en) * | 1996-07-15 | 1998-06-16 | Universal Preservation Technologies, Inc. | Preservation by foam formation |
US5645587A (en) | 1996-06-05 | 1997-07-08 | Chanda; Jyotirmay | Prevention of calcification and degeneration of biological tissue grafts for implantation in humans |
US5695820A (en) | 1996-06-20 | 1997-12-09 | Hewlett-Packard Company | Method for alleviating marangoni flow-induced print defects in ink-jet printing |
SE506983C2 (en) | 1996-07-02 | 1998-03-09 | Akzo Nobel Nv | Orthoester based polymer, process for its preparation and use thereof |
US5782931A (en) | 1996-07-30 | 1998-07-21 | Baxter International Inc. | Methods for mitigating calcification and improving durability in glutaraldehyde-fixed bioprostheses and articles manufactured by such methods |
US6121041A (en) * | 1996-07-31 | 2000-09-19 | St. Jude Medical, Inc. | Use of microorganisms for decellularizing bioprosthetic tissue |
WO1998007452A1 (en) | 1996-08-21 | 1998-02-26 | Sulzer Vascutek Limited | Method of sterilising material for implantation |
US6666892B2 (en) * | 1996-08-23 | 2003-12-23 | Cook Biotech Incorporated | Multi-formed collagenous biomaterial medical device |
US6764509B2 (en) | 1996-09-06 | 2004-07-20 | Carbomedics Inc. | Prosthetic heart valve with surface modification |
US5782914A (en) | 1996-11-29 | 1998-07-21 | Bio-Vascular, Inc. | Method for preparing heterogeneous tissue grafts |
US5856172A (en) * | 1997-01-03 | 1999-01-05 | Quality Technologies, Llc | Preservation of microorganisms in a vial with a cap comprising an immobilized desiccant |
JP4271262B2 (en) * | 1997-02-10 | 2009-06-03 | バイオメディカル デザイン インコーポレイテッド | Sterilization method |
US6506339B1 (en) * | 1997-02-10 | 2003-01-14 | Biomedical Design, Inc. | Method of sterilization |
US5856102A (en) * | 1997-02-26 | 1999-01-05 | Bierke-Nelson; Diane Lynn | Home/self-storage to improve DNA banking |
US5865244A (en) * | 1997-03-25 | 1999-02-02 | Behr America, Inc. | Plastic header tank matrix and method of making same |
US5928281A (en) | 1997-03-27 | 1999-07-27 | Baxter International Inc. | Tissue heart valves |
DK0987998T3 (en) * | 1997-04-11 | 2005-01-17 | Cryolife Inc | Decellulation of tissue |
US6206917B1 (en) | 1997-05-02 | 2001-03-27 | St. Jude Medical, Inc. | Differential treatment of prosthetic devices |
US5993844A (en) | 1997-05-08 | 1999-11-30 | Organogenesis, Inc. | Chemical treatment, without detergents or enzymes, of tissue to form an acellular, collagenous matrix |
US6156030A (en) | 1997-06-04 | 2000-12-05 | Y-Beam Technologies, Inc. | Method and apparatus for high precision variable rate material removal and modification |
US5987720A (en) | 1997-07-08 | 1999-11-23 | Yamamoto; William Shigeru | Portable tomb for resurrection from mummified tissue DNA |
US6117979A (en) | 1997-08-18 | 2000-09-12 | Medtronic, Inc. | Process for making a bioprosthetic device and implants produced therefrom |
US6166184A (en) | 1997-08-18 | 2000-12-26 | Medtronic Inc. | Process for making a bioprosthetic device |
US6613278B1 (en) | 1998-11-13 | 2003-09-02 | Regeneration Technologies, Inc. | Tissue pooling process |
US5862806A (en) * | 1997-10-30 | 1999-01-26 | Mitroflow International, Inc. | Borohydride reduction of biological tissues |
US6267782B1 (en) * | 1997-11-20 | 2001-07-31 | St. Jude Medical, Inc. | Medical article with adhered antimicrobial metal |
US6008292A (en) | 1997-12-02 | 1999-12-28 | Baxter International Inc. | Method for inhibiting calcification of aldehyde-fixed bioprosthetic materials |
US5921980A (en) | 1997-12-03 | 1999-07-13 | University Of Kentucky Research Foundation | Laser skin graft harvesting apparatus and related method |
US6254635B1 (en) | 1998-02-02 | 2001-07-03 | St. Jude Medical, Inc. | Calcification-resistant medical articles |
US6093530A (en) | 1998-02-06 | 2000-07-25 | Sulzer Carbomedics Inc. | Non-calcific biomaterial by glutaraldehyde followed by oxidative fixation |
US6251579B1 (en) | 1998-02-13 | 2001-06-26 | Sulzer Carbomedics Inc. | Oxidative stabilization of collagen containing materials |
US6383732B1 (en) * | 1999-02-11 | 2002-05-07 | Crosscart, Inc. | Method of preparing xenograft heart valves |
US6258320B1 (en) | 1998-04-09 | 2001-07-10 | David H. Persing | Method for preservation of nucleic acids |
WO1999058082A2 (en) | 1998-05-14 | 1999-11-18 | The Cleveland Clinic Foundation | Processing of implantable animal tissues for dry storage |
US6933326B1 (en) * | 1998-06-19 | 2005-08-23 | Lifecell Coporation | Particulate acellular tissue matrix |
US6630001B2 (en) | 1998-06-24 | 2003-10-07 | International Heart Institute Of Montana Foundation | Compliant dehyrated tissue for implantation and process of making the same |
US6293970B1 (en) * | 1998-06-30 | 2001-09-25 | Lifenet | Plasticized bone and soft tissue grafts and methods of making and using same |
US6734018B2 (en) * | 1999-06-07 | 2004-05-11 | Lifenet | Process for decellularizing soft-tissue engineered medical implants, and decellularized soft-tissue medical implants produced |
US20030217415A1 (en) | 1998-06-30 | 2003-11-27 | Katrina Crouch | Plasticized bone grafts and methods of making and using same |
US6394096B1 (en) * | 1998-07-15 | 2002-05-28 | Corazon Technologies, Inc. | Method and apparatus for treatment of cardiovascular tissue mineralization |
US6527979B2 (en) * | 1999-08-27 | 2003-03-04 | Corazon Technologies, Inc. | Catheter systems and methods for their use in the treatment of calcified vascular occlusions |
US6156531A (en) | 1998-07-20 | 2000-12-05 | Sulzer Carbomedics Inc. | Cross-linking tissue with a compound having a C8 to C40 aliphatic chain |
US6448076B2 (en) | 1998-09-15 | 2002-09-10 | The Regents Of The University Of Michigan | Method for chemically acellularizing a biological tissue sample |
US6214054B1 (en) * | 1998-09-21 | 2001-04-10 | Edwards Lifesciences Corporation | Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby |
US6334873B1 (en) | 1998-09-28 | 2002-01-01 | Autogenics | Heart valve having tissue retention with anchors and an outer sheath |
ES2234311T3 (en) * | 1998-09-30 | 2005-06-16 | Medtronic, Inc. | PROCEDURE THAT ALLOWS TO REDUCE THE MINERALIZATION OF A FABRIC USED FOR A TRANSPLANT. |
US6214055B1 (en) * | 1998-10-30 | 2001-04-10 | Mures Cardiovascular Research, Inc. | Method and kit for rapid preparation of autologous tissue medical devices |
US6066160A (en) * | 1998-11-23 | 2000-05-23 | Quickie Llc | Passive knotless suture terminator for use in minimally invasive surgery and to facilitate standard tissue securing |
US6375680B1 (en) * | 1998-12-01 | 2002-04-23 | St. Jude Medical, Inc. | Substrates for forming synthetic tissues |
US6106555A (en) * | 1998-12-15 | 2000-08-22 | Av Healing Llc | Method for tissue fixation |
US6364905B1 (en) * | 1999-01-27 | 2002-04-02 | Sulzer Carbomedics Inc. | Tri-composite, full root, stentless valve |
US6267786B1 (en) | 1999-02-11 | 2001-07-31 | Crosscart, Inc. | Proteoglycan-reduced soft tissue xenografts |
EP2193809B1 (en) | 1999-02-22 | 2015-04-08 | University of Connecticut | Albumin-free factor VIII formulations |
US6287338B1 (en) | 1999-03-10 | 2001-09-11 | Sulzer Carbomedics Inc. | Pre-stressing devices incorporating materials subject to stress softening |
US6322593B1 (en) | 1999-04-09 | 2001-11-27 | Sulzer Carbomedics Inc. | Method for treating cross-linked biological tissues |
US6177514B1 (en) * | 1999-04-09 | 2001-01-23 | Sulzer Carbomedics Inc. | Blocked functional reagants for cross-linking biological tissues |
US6132986A (en) | 1999-04-23 | 2000-10-17 | Sulzer Carbomedics Inc. | Tissue crosslinking for bioprostheses using activated difunctional or polyfunctional acids |
US6328762B1 (en) | 1999-04-27 | 2001-12-11 | Sulzer Biologics, Inc. | Prosthetic grafts |
US6790229B1 (en) | 1999-05-25 | 2004-09-14 | Eric Berreklouw | Fixing device, in particular for fixing to vascular wall tissue |
US6174331B1 (en) | 1999-07-19 | 2001-01-16 | Sulzer Carbomedics Inc. | Heart valve leaflet with reinforced free margin |
US6312474B1 (en) | 1999-09-15 | 2001-11-06 | Bio-Vascular, Inc. | Resorbable implant materials |
US6352708B1 (en) | 1999-10-14 | 2002-03-05 | The International Heart Institute Of Montana Foundation | Solution and method for treating autologous tissue for implant operation |
WO2001028325A2 (en) | 1999-10-20 | 2001-04-26 | Grain Processing Corporation | Compositions including reduced malto-oligosaccharide preserving agents |
US6322994B1 (en) | 1999-11-04 | 2001-11-27 | Genetix Limited | Method of freeze-drying organisms |
US6479079B1 (en) | 1999-12-13 | 2002-11-12 | Sulzer Carbomedics Inc. | Anticalcification treatments for fixed biomaterials |
US6576265B1 (en) * | 1999-12-22 | 2003-06-10 | Acell, Inc. | Tissue regenerative composition, method of making, and method of use thereof |
US6376244B1 (en) * | 1999-12-29 | 2002-04-23 | Children's Medical Center Corporation | Methods and compositions for organ decellularization |
US6471723B1 (en) | 2000-01-10 | 2002-10-29 | St. Jude Medical, Inc. | Biocompatible prosthetic tissue |
US6872226B2 (en) | 2001-01-29 | 2005-03-29 | 3F Therapeutics, Inc. | Method of cutting material for use in implantable medical device |
ES2307590T3 (en) | 2000-01-27 | 2008-12-01 | 3F Therapeutics, Inc | HEART VALVE PROTESICA. |
US6391538B1 (en) * | 2000-02-09 | 2002-05-21 | The Children's Hospital Of Philadelphia | Stabilization of implantable bioprosthetic tissue |
US6610088B1 (en) | 2000-05-03 | 2003-08-26 | Shlomo Gabbay | Biologically covered heart valve prosthesis |
US6653062B1 (en) | 2000-07-26 | 2003-11-25 | Wisconsin Alumni Research Foundation | Preservation and storage medium for biological materials |
US6605667B1 (en) | 2000-09-08 | 2003-08-12 | Closure Medical Corporation | Antioxidant enriched adhesive compositions and storage containers therefor |
US6696074B2 (en) * | 2000-12-04 | 2004-02-24 | Tei Biosciences, Inc. | Processing fetal or neo-natal tissue to produce a scaffold for tissue engineering |
US20020111532A1 (en) | 2000-12-19 | 2002-08-15 | Pathak Chandrashekhar P. | Tris(hydroxymethyl)phosphino compounds as tissue crosslinking agents |
US6468660B2 (en) | 2000-12-29 | 2002-10-22 | St. Jude Medical, Inc. | Biocompatible adhesives |
US20020091441A1 (en) | 2001-01-05 | 2002-07-11 | Guzik Donald S. | Focused beam cutting of materials |
US6377143B1 (en) | 2001-03-16 | 2002-04-23 | Eaton Corporation | Weld-free contact system for electromagnetic contactors |
US7078163B2 (en) | 2001-03-30 | 2006-07-18 | Medtronic, Inc. | Process for reducing mineralization of tissue used in transplantation |
GB2375771A (en) * | 2001-05-24 | 2002-11-27 | Univ Leeds | Decellularisation of tissue implant material |
US6589591B1 (en) | 2001-07-10 | 2003-07-08 | Baylor College Of Medicine | Method for treating medical devices using glycerol and an antimicrobial agent |
GB0125925D0 (en) | 2001-10-29 | 2001-12-19 | Univ Glasgow | Mitral valve prosthesis |
US7201771B2 (en) | 2001-12-27 | 2007-04-10 | Arbor Surgical Technologies, Inc. | Bioprosthetic heart valve |
US7189258B2 (en) | 2002-01-02 | 2007-03-13 | Medtronic, Inc. | Heart valve system |
US6878168B2 (en) | 2002-01-03 | 2005-04-12 | Edwards Lifesciences Corporation | Treatment of bioprosthetic tissues to mitigate post implantation calcification |
US8308797B2 (en) | 2002-01-04 | 2012-11-13 | Colibri Heart Valve, LLC | Percutaneously implantable replacement heart valve device and method of making same |
US7141064B2 (en) | 2002-05-08 | 2006-11-28 | Edwards Lifesciences Corporation | Compressed tissue for heart valve leaflets |
US7578843B2 (en) * | 2002-07-16 | 2009-08-25 | Medtronic, Inc. | Heart valve prosthesis |
US6908591B2 (en) * | 2002-07-18 | 2005-06-21 | Clearant, Inc. | Methods for sterilizing biological materials by irradiation over a temperature gradient |
US7008763B2 (en) | 2002-09-23 | 2006-03-07 | Cheung David T | Method to treat collagenous connective tissue for implant remodeled by host cells into living tissue |
US7189259B2 (en) | 2002-11-26 | 2007-03-13 | Clemson University | Tissue material and process for bioprosthesis |
WO2004082536A1 (en) | 2003-03-20 | 2004-09-30 | Aortech International Plc | Valve |
US20040193259A1 (en) | 2003-03-25 | 2004-09-30 | Shlomo Gabbay | Sizing apparatus for cardiac prostheses and method of using same |
US20050211680A1 (en) | 2003-05-23 | 2005-09-29 | Mingwei Li | Systems and methods for laser texturing of surfaces of a substrate |
IL156626A (en) | 2003-06-24 | 2009-12-24 | Yeda Res & Dev | System for selective cell destruction |
US7367969B2 (en) | 2003-08-11 | 2008-05-06 | Raydiance, Inc. | Ablative material removal with a preset removal rate or volume or depth |
US7143769B2 (en) | 2003-08-11 | 2006-12-05 | Richard Stoltz | Controlling pulse energy of an optical amplifier by controlling pump diode current |
US9022037B2 (en) | 2003-08-11 | 2015-05-05 | Raydiance, Inc. | Laser ablation method and apparatus having a feedback loop and control unit |
DE602004021022D1 (en) | 2003-10-28 | 2009-06-18 | Medtronic Inc | METHOD FOR PRODUCING NETWORKED MATERIALS AND BIOPROTHETIC DEVICES |
US7955788B2 (en) | 2003-10-30 | 2011-06-07 | Medtronic, Inc. | Bioprosthetic tissue preparation with synthetic hydrogels |
US7648676B2 (en) | 2004-04-20 | 2010-01-19 | Rti Biologics, Inc. | Process and apparatus for treating implants comprising soft tissue |
WO2006026325A2 (en) | 2004-08-26 | 2006-03-09 | Pathak Chandrashekhar P | Implantable tissue compositions and method |
US20060110370A1 (en) | 2004-11-23 | 2006-05-25 | Pathak Chandrashenkhar P | Treatments for reduction of cytotoxicity and viral contamination of implantable medical devices |
CA2591882C (en) | 2004-12-24 | 2013-10-15 | Celxcel Pty Ltd | Calcification resistant biomaterial produced by treating with an alcohol prior to cross-linking |
US20060177426A1 (en) | 2005-02-09 | 2006-08-10 | Cecil Gibson | Method of preserving lyophilized microorganisms for transport, storage and recovery of viable microorganisms |
WO2006099334A2 (en) | 2005-03-11 | 2006-09-21 | Wake Forest University Health Sciences | Production of tissue engineered heart valves |
US20060217804A1 (en) | 2005-03-25 | 2006-09-28 | Dove Jeffrey S | Treatment of bioprosthetic tissues to mitigate post implantation calcification |
US7914569B2 (en) | 2005-05-13 | 2011-03-29 | Medtronics Corevalve Llc | Heart valve prosthesis and methods of manufacture and use |
US7238200B2 (en) | 2005-06-03 | 2007-07-03 | Arbor Surgical Technologies, Inc. | Apparatus and methods for making leaflets and valve prostheses including such leaflets |
US20070292459A1 (en) | 2005-07-18 | 2007-12-20 | Cooper Sarah M | Halloysite microtubule processes, structures, and compositions |
US8470022B2 (en) | 2005-08-31 | 2013-06-25 | Cook Biotech Incorporated | Implantable valve |
US7682304B2 (en) | 2005-09-21 | 2010-03-23 | Medtronic, Inc. | Composite heart valve apparatus manufactured using techniques involving laser machining of tissue |
US8075615B2 (en) | 2006-03-28 | 2011-12-13 | Medtronic, Inc. | Prosthetic cardiac valve formed from pericardium material and methods of making same |
US10876193B2 (en) | 2006-09-29 | 2020-12-29 | University Of Rochester | Nanostructured materials, methods, and applications |
US20080299408A1 (en) | 2006-09-29 | 2008-12-04 | University Of Rochester | Femtosecond Laser Pulse Surface Structuring Methods and Materials Resulting Therefrom |
EP2077718B2 (en) | 2006-10-27 | 2022-03-09 | Edwards Lifesciences Corporation | Biological tissue for surgical implantation |
US8105375B2 (en) | 2007-01-19 | 2012-01-31 | The Cleveland Clinic Foundation | Method for implanting a cardiovascular valve |
US9101691B2 (en) | 2007-06-11 | 2015-08-11 | Edwards Lifesciences Corporation | Methods for pre-stressing and capping bioprosthetic tissue |
FR2917625B1 (en) | 2007-06-20 | 2009-09-18 | Perouse Soc Par Actions Simpli | TREATMENT OF IMPLANTABLE MEDICAL DEVICES RESISTANT TO CALCIFICATION |
US8357387B2 (en) * | 2007-12-21 | 2013-01-22 | Edwards Lifesciences Corporation | Capping bioprosthetic tissue to reduce calcification |
WO2009129483A1 (en) | 2008-04-17 | 2009-10-22 | Musculoskeletal Transplant Foundation | Ultrashort pulse laser applications |
US8136218B2 (en) | 2008-04-29 | 2012-03-20 | Medtronic, Inc. | Prosthetic heart valve, prosthetic heart valve assembly and method for making same |
EP4119097A1 (en) | 2008-06-06 | 2023-01-18 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
US9066785B2 (en) * | 2009-04-06 | 2015-06-30 | Medtronic Vascular, Inc. | Packaging systems for percutaneously deliverable bioprosthetic valves |
EP2437857B1 (en) * | 2009-06-05 | 2019-05-29 | Tyco Fire Products LP | Concealed sprinkler |
AU2011223708A1 (en) | 2010-03-01 | 2012-09-27 | Colibri Heart Valve Llc | Percutaneously deliverable heart valve and methods associated therewith |
WO2011109433A2 (en) | 2010-03-01 | 2011-09-09 | Vela Biosystems Llc | Tissue for prosthetic implants and grafts, and methods associated therewith |
US8679404B2 (en) | 2010-03-05 | 2014-03-25 | Edwards Lifesciences Corporation | Dry prosthetic heart valve packaging system |
NZ602066A (en) | 2010-03-23 | 2013-09-27 | Edwards Lifesciences Corp | Methods of conditioning sheet bioprosthetic tissue |
JP2013526388A (en) | 2010-05-25 | 2013-06-24 | イエナバルブ テクノロジー インク | Artificial heart valve, and transcatheter delivery prosthesis comprising an artificial heart valve and a stent |
IT1400545B1 (en) | 2010-06-09 | 2013-06-11 | Sorin Biomedica Cardio Srl | PROCEDURE FOR THE PREPARATION OF BIOLOGICAL FABRIC FOR BIOLOGICAL PROSTHESIS. |
IT1400544B1 (en) | 2010-06-09 | 2013-06-11 | Sorin Biomedica Cardio Srl | PROCESS OF DETOXIFICATION OF BIOLOGICAL FABRIC. |
US8906601B2 (en) | 2010-06-17 | 2014-12-09 | Edwardss Lifesciences Corporation | Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates |
US8377143B2 (en) | 2010-07-06 | 2013-02-19 | Cryolife, Inc. | Tissue implants for implantation and methods for preparing the same |
US8475827B2 (en) | 2010-07-06 | 2013-07-02 | Cryolife, Inc. | Tissue implants for implantation and methods for preparing the same |
EP2608815B1 (en) | 2010-08-24 | 2018-03-21 | Collagen Solutions NZ Limited | Biomaterials with enhanced properties and devices made therefrom |
CN103228231A (en) | 2010-09-23 | 2013-07-31 | 科利柏心脏瓣膜有限责任公司 | Percutaneously deliverable heart or blood vessel valve with frame having abluminally situated tissue membrane |
US9351829B2 (en) | 2010-11-17 | 2016-05-31 | Edwards Lifesciences Corporation | Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability |
SG191008A1 (en) | 2010-12-14 | 2013-07-31 | Colibri Heart Valve Llc | Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets |
EP2729094A4 (en) | 2011-07-08 | 2015-08-05 | Univ California | Method of using medical implants |
US20130122583A1 (en) | 2011-11-10 | 2013-05-16 | Celxcel Pty Ltd | Sterilization process |
-
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- 2008-12-18 US US12/338,872 patent/US8357387B2/en active Active
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Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030135284A1 (en) * | 1998-06-30 | 2003-07-17 | Katrina Crouch | Plasticized bone grafts and methods of making and using same |
WO2000032252A1 (en) * | 1998-11-27 | 2000-06-08 | University Of Sheffield | Skin composites |
US20060159641A1 (en) * | 2002-01-25 | 2006-07-20 | Biomedical Design, Inc. | Variably crosslinked tissue |
US20060217805A1 (en) * | 2005-03-25 | 2006-09-28 | Dove Jeffrey S | Treatment of bioprosthetic tissues to mitigate post implantation calcification |
Non-Patent Citations (2)
Title |
---|
CHANDA J ET AL: "Heparin in calcification prevention of porcine pericardial bioprostheses", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 18, no. 16, 1 August 1997 (1997-08-01), pages 1109 - 1113, XP004083119, ISSN: 0142-9612 * |
ZILLA P ET AL: "Carbodiimide Treatment Dramatically Potentiates the Anticalcific Effect of Alpha-Amino Oleic Acid on Glutaraldehyde-Fixed Aortic Wall Tissue", THE ANNALS OF THORACIC SURGERY, ELSEVIER, vol. 79, no. 3, 1 March 2005 (2005-03-01), pages 905 - 910, XP004761947, ISSN: 0003-4975 * |
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US20090164005A1 (en) | 2009-06-25 |
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US9320830B2 (en) | 2016-04-26 |
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US20130134064A1 (en) | 2013-05-30 |
EP2234657A2 (en) | 2010-10-06 |
US20160235528A1 (en) | 2016-08-18 |
EP2234657B1 (en) | 2015-08-19 |
EP2647393B1 (en) | 2018-10-17 |
US9029418B2 (en) | 2015-05-12 |
US10966822B2 (en) | 2021-04-06 |
US20190151083A1 (en) | 2019-05-23 |
CN101965205A (en) | 2011-02-02 |
CN103705980A (en) | 2014-04-09 |
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