WO2009079388A3 - Drug delivery cuff - Google Patents

Drug delivery cuff Download PDF

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Publication number
WO2009079388A3
WO2009079388A3 PCT/US2008/086637 US2008086637W WO2009079388A3 WO 2009079388 A3 WO2009079388 A3 WO 2009079388A3 US 2008086637 W US2008086637 W US 2008086637W WO 2009079388 A3 WO2009079388 A3 WO 2009079388A3
Authority
WO
WIPO (PCT)
Prior art keywords
drug delivery
graft
conduit
delivery cuff
drug
Prior art date
Application number
PCT/US2008/086637
Other languages
French (fr)
Other versions
WO2009079388A2 (en
Inventor
Stephen R. Hanson
Original Assignee
Oregon Health & Science University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oregon Health & Science University filed Critical Oregon Health & Science University
Priority to EP08861925A priority Critical patent/EP2219725A4/en
Priority to US12/747,048 priority patent/US8808255B2/en
Priority to CA2746807A priority patent/CA2746807A1/en
Publication of WO2009079388A2 publication Critical patent/WO2009079388A2/en
Publication of WO2009079388A3 publication Critical patent/WO2009079388A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/14244Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2/064Blood vessels with special features to facilitate anastomotic coupling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067Means for introducing or releasing pharmaceutical products into the body

Abstract

Embodiments provide a drug delivery cuff including a drug reservoir. In an embodiment, an integrated drug pump may be provided. A drug delivery cuff in accordance with an embodiment may be placed around any suitable vascular graft (e.g., ePTFE) or directly around any natural tissue conduit (e.g., perivascularly), at any position along the graft/conduit or overlapping a graft and conduit, either at the time of graft surgical placement or separate therefrom.
PCT/US2008/086637 2007-12-14 2008-12-12 Drug delivery cuff WO2009079388A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP08861925A EP2219725A4 (en) 2007-12-14 2008-12-12 Drug delivery cuff
US12/747,048 US8808255B2 (en) 2007-12-14 2008-12-12 Drug delivery cuff
CA2746807A CA2746807A1 (en) 2007-12-14 2008-12-12 Drug delivery cuff

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1381007P 2007-12-14 2007-12-14
US61/013,810 2007-12-14

Publications (2)

Publication Number Publication Date
WO2009079388A2 WO2009079388A2 (en) 2009-06-25
WO2009079388A3 true WO2009079388A3 (en) 2009-09-03

Family

ID=40796107

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/086637 WO2009079388A2 (en) 2007-12-14 2008-12-12 Drug delivery cuff

Country Status (4)

Country Link
US (1) US8808255B2 (en)
EP (1) EP2219725A4 (en)
CA (1) CA2746807A1 (en)
WO (1) WO2009079388A2 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110295181A1 (en) 2008-03-05 2011-12-01 Hemosphere, Inc. Implantable and removable customizable body conduit
EP2405967B1 (en) * 2009-03-12 2020-09-23 Delpor, Inc. Implantable device for long-term delivery of drugs
US20110106020A1 (en) * 2009-10-29 2011-05-05 Elmer Lucas B Catheter For Deactivating At Least A Portion of the Digestive Enzymes In An Amount Of Bile
EP3338736B1 (en) * 2010-03-09 2020-04-29 Solinas Medical Inc. Self-closing devices
KR101241059B1 (en) * 2011-03-04 2013-03-11 연세대학교 산학협력단 Device and Method for Delivery of Drug to the Exterior of Vascular Vessels using Micro-needle
WO2012125957A2 (en) * 2011-03-16 2012-09-20 Mayo Foundation For Medical Education And Research Methods and materials for reducing venous stenosis formation of an arteriovenous fistula or graft
BR112014005094A2 (en) 2011-09-06 2017-03-28 Hemosphere Inc vascular access system with connector
US8685106B2 (en) 2011-11-15 2014-04-01 Abraham Lin Method of a pharmaceutical delivery system for use within a joint replacement
US20150051532A1 (en) * 2013-08-13 2015-02-19 Cryolife, Inc. Systems and methods for a fluid carrying conduit of a vascular access system
WO2015094514A1 (en) 2013-12-20 2015-06-25 Cryolife, Inc. Vascular access system with reinforcement member
AU2015373055A1 (en) * 2014-12-29 2017-08-10 Ajoy I. Singh A system and method for treating artery
FR3054137B1 (en) * 2016-07-21 2021-08-27 Univ Angers LOCOREGIONAL INJECTION IMPLANTABLE MEDICAL DEVICE
US10499920B2 (en) 2016-11-10 2019-12-10 Merit Medical Systems, Inc. Anchor device for vascular anastomosis
EP3568173A4 (en) 2017-01-12 2020-11-25 Merit Medical Systems, Inc. Methods and systems for selection and use of connectors between conduits
WO2018140306A1 (en) 2017-01-25 2018-08-02 Merit Medical Systems, Inc. Methods and systems for facilitating laminar flow between conduits
EP3592401A4 (en) 2017-03-06 2021-01-06 Merit Medical Systems, Inc. Vascular access assembly declotting systems and methods
WO2018175850A1 (en) 2017-03-24 2018-09-27 Merit Medical Systems, Inc. Subcutaneous vascular assemblies for improving blood flow and related devices and methods
EP3651829A4 (en) 2017-07-14 2021-04-21 Merit Medical Systems, Inc. Releasable conduit connectors
EP3655086A4 (en) 2017-07-20 2021-04-07 Merit Medical Systems, Inc. Methods and systems for coupling conduits
CN107497039B (en) * 2017-10-18 2020-04-17 河南科技大学第一附属医院 Medical oncology device of dosing
US11331458B2 (en) 2017-10-31 2022-05-17 Merit Medical Systems, Inc. Subcutaneous vascular assemblies for improving blood flow and related devices and methods

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5405378A (en) * 1992-05-20 1995-04-11 Strecker; Ernst P. Device with a prosthesis implantable in the body of a patient
US6471689B1 (en) * 1999-08-16 2002-10-29 Thomas Jefferson University Implantable drug delivery catheter system with capillary interface
US6981977B2 (en) * 2001-10-26 2006-01-03 Atrium Medical Corporation Body fluid cartridge exchange platform device
US7058447B2 (en) * 2000-09-26 2006-06-06 Medtronic, Inc. Method and system for directing blood flow during a medical procedure

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3797485A (en) * 1971-03-26 1974-03-19 Alza Corp Novel drug delivery device for administering drug into blood circulation in blood vessel
US5024671A (en) * 1988-09-19 1991-06-18 Baxter International Inc. Microporous vascular graft
AU6747790A (en) * 1989-11-13 1991-06-13 President And Fellows Of Harvard College Extraluminal regulation of the growth and repair of tubular structures in vivo
US5527532A (en) * 1989-11-13 1996-06-18 President And Fellows Of Harvard College Extraluminal regulation of the growth and repair of tubular structures in vivo
ATE139126T1 (en) * 1990-09-10 1996-06-15 Synthes Ag MEMBRANE FOR BONE REGENERATION
US5411550A (en) * 1991-09-16 1995-05-02 Atrium Medical Corporation Implantable prosthetic device for the delivery of a bioactive material
US5500013A (en) * 1991-10-04 1996-03-19 Scimed Life Systems, Inc. Biodegradable drug delivery vascular stent
US5405325A (en) * 1991-10-17 1995-04-11 Labs; Joseph D. Access graft
US5523092A (en) * 1993-04-14 1996-06-04 Emory University Device for local drug delivery and methods for using the same
US5985307A (en) * 1993-04-14 1999-11-16 Emory University Device and method for non-occlusive localized drug delivery
US5399352A (en) * 1993-04-14 1995-03-21 Emory University Device for local drug delivery and methods for using the same
US5716410A (en) * 1993-04-30 1998-02-10 Scimed Life Systems, Inc. Temporary stent and method of use
US5637113A (en) * 1994-12-13 1997-06-10 Advanced Cardiovascular Systems, Inc. Polymer film for wrapping a stent structure
US5983134A (en) * 1995-04-23 1999-11-09 Electromagnetic Bracing Systems Inc. Electrophoretic cuff apparatus drug delivery system
IL113459A (en) * 1995-04-23 2000-07-16 Electromagnetic Bracing System Electrophoretic cuff apparatus
US5800512A (en) * 1996-01-22 1998-09-01 Meadox Medicals, Inc. PTFE vascular graft
EP0941116B1 (en) 1996-11-01 2005-01-19 Ark Therapeutics Limited Use of vegf for the manufacture of a medicament for the treatment or prevention of intimal hyperplasia and delivery device
US5824050A (en) * 1996-12-03 1998-10-20 Atrium Medical Corporation Prosthesis with in-wall modulation
US6117147A (en) * 1998-09-30 2000-09-12 Sulzer Carbomedics Inc. Device and method for reinforcing an anastomotic site
US6355063B1 (en) * 2000-01-20 2002-03-12 Impra, Inc. Expanded PTFE drug delivery graft
US6776796B2 (en) * 2000-05-12 2004-08-17 Cordis Corportation Antiinflammatory drug and delivery device
CA2414075A1 (en) * 2000-06-05 2001-12-13 Theragenics Corporation A device for delivering a therapeutic dosage
US6534693B2 (en) * 2000-11-06 2003-03-18 Afmedica, Inc. Surgically implanted devices having reduced scar tissue formation
AP2003002828A0 (en) * 2001-01-16 2003-09-30 Vascular Therapies Llc Implantable device containing resorbable matrix material and anti-proliferative drugs for preventing or treating failure of hemodialysis vascular access and other vascular grafts.
US6827737B2 (en) * 2001-09-25 2004-12-07 Scimed Life Systems, Inc. EPTFE covering for endovascular prostheses and method of manufacture
CN1684725A (en) * 2002-09-26 2005-10-19 血管技术国际股份公司 Perivascular wraps
US20050070989A1 (en) * 2002-11-13 2005-03-31 Whye-Kei Lye Medical devices having porous layers and methods for making the same
US9770349B2 (en) * 2002-11-13 2017-09-26 University Of Virginia Patent Foundation Nanoporous stents with enhanced cellular adhesion and reduced neointimal formation
US7351257B2 (en) * 2003-04-17 2008-04-01 Intermed, Inc. Vascular graft device
US20050060020A1 (en) * 2003-09-17 2005-03-17 Scimed Life Systems, Inc. Covered stent with biologically active material
US7594885B2 (en) * 2004-02-20 2009-09-29 Ethicon Endo-Surgery, Inc. Method for implanting an adjustable band
US7611840B2 (en) * 2004-08-03 2009-11-03 Agency For Science, Technology And Research Method and device for the treatment of biological samples
JP2008537898A (en) * 2005-02-11 2008-10-02 ミカーディア コーポレーション Dynamically adjustable gastric implant and method for treating obesity using the same
US7310557B2 (en) * 2005-04-29 2007-12-18 Maschino Steven E Identification of electrodes for nerve stimulation in the treatment of eating disorders
GB0515140D0 (en) 2005-07-22 2005-08-31 Ark Therapeutics Ltd Therapeutic device
EP2073765A2 (en) * 2006-09-25 2009-07-01 Boston Scientific Limited Injection of therapeutic into porous regions of a medical device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5405378A (en) * 1992-05-20 1995-04-11 Strecker; Ernst P. Device with a prosthesis implantable in the body of a patient
US6471689B1 (en) * 1999-08-16 2002-10-29 Thomas Jefferson University Implantable drug delivery catheter system with capillary interface
US7058447B2 (en) * 2000-09-26 2006-06-06 Medtronic, Inc. Method and system for directing blood flow during a medical procedure
US6981977B2 (en) * 2001-10-26 2006-01-03 Atrium Medical Corporation Body fluid cartridge exchange platform device

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2219725A4 *

Also Published As

Publication number Publication date
EP2219725A2 (en) 2010-08-25
CA2746807A1 (en) 2009-06-25
EP2219725A4 (en) 2011-05-18
WO2009079388A2 (en) 2009-06-25
US20100268188A1 (en) 2010-10-21
US8808255B2 (en) 2014-08-19

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