WO2009053889A3 - Manipulation of particles by dielectrophoresis - Google Patents

Manipulation of particles by dielectrophoresis Download PDF

Info

Publication number
WO2009053889A3
WO2009053889A3 PCT/IB2008/054305 IB2008054305W WO2009053889A3 WO 2009053889 A3 WO2009053889 A3 WO 2009053889A3 IB 2008054305 W IB2008054305 W IB 2008054305W WO 2009053889 A3 WO2009053889 A3 WO 2009053889A3
Authority
WO
WIPO (PCT)
Prior art keywords
electrodes
particles
region
driving
manipulation
Prior art date
Application number
PCT/IB2008/054305
Other languages
French (fr)
Other versions
WO2009053889A2 (en
Inventor
Paul L. Collins
Original Assignee
Koninklijke Philips Electronics N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips Electronics N.V. filed Critical Koninklijke Philips Electronics N.V.
Publication of WO2009053889A2 publication Critical patent/WO2009053889A2/en
Publication of WO2009053889A3 publication Critical patent/WO2009053889A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C5/00—Separating dispersed particles from liquids by electrostatic effect
    • B03C5/02—Separators
    • B03C5/022—Non-uniform field separators
    • B03C5/028—Non-uniform field separators using travelling electric fields, i.e. travelling wave dielectrophoresis [TWD]

Abstract

The present invention provides a dielectrophoretic device for manipulation of at least a first and a second type of particles (1, 2) present in a sample fluid. The device comprises at least one array (3) of electrodes (4), the array (3) comprising at least a plurality of electrodes (4) in a first region (5) and a plurality of electrodes (4) in a second region (6), driving means (32) for driving the electrodes (4) of the first and second region (5, 6) of the array (3) to generate a travelling wave dielectrophoretic force to be exerted on the at least first and second types of particles (1, 2), and a controller (30) for controlling the driving means (32), the controller (30) being adapted for first driving the electrodes (4) of the first and second region (5, 6) with a same driving signal and subsequently changing the driving signal to electrodes (4) of at least one of the first and second region (5, 6) so as to separate at least some particles (1) of the first type from the particles (2) of the second type. The present invention also provides a method for forming such a dielectrophoretic device, a method for manipulation of at least a first and a second type of particles (1, 2) present in a sample fluid and a controller (30) for controlled driving of electrodes (4) of such a dielectrophoretic device.
PCT/IB2008/054305 2007-10-22 2008-10-20 Manipulation of particles by dielectrophoresis WO2009053889A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07119025A EP2052783A1 (en) 2007-10-22 2007-10-22 Manipulation of particles by dielectrophoresis
EP07119025.0 2007-10-22

Publications (2)

Publication Number Publication Date
WO2009053889A2 WO2009053889A2 (en) 2009-04-30
WO2009053889A3 true WO2009053889A3 (en) 2009-10-15

Family

ID=39217890

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2008/054305 WO2009053889A2 (en) 2007-10-22 2008-10-20 Manipulation of particles by dielectrophoresis

Country Status (2)

Country Link
EP (1) EP2052783A1 (en)
WO (1) WO2009053889A2 (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5653859A (en) * 1993-01-21 1997-08-05 Parton; Adrian Methods of analysis/separation
WO1997034689A1 (en) * 1996-03-18 1997-09-25 University College Of North Wales Apparatus with electrode arrays for carrying out chemical, physical or physico-chemical reactions
WO2001005512A1 (en) * 1999-07-20 2001-01-25 University Of Wales, Bangor Dielectrophoretic apparatus & method
US6185084B1 (en) * 1997-10-06 2001-02-06 California Institute Of Technology Electrostatic particle transportation
US6596143B1 (en) * 2000-09-27 2003-07-22 Aviva Biosciences Corporation Apparatus for switching and manipulating particles and method of use thereof
US20050123992A1 (en) * 2003-12-03 2005-06-09 Palo Alto Research Center Incorporated Concentration and focusing of bio-agents and micron-sized particles using traveling wave grids

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750015A (en) * 1990-02-28 1998-05-12 Soane Biosciences Method and device for moving molecules by the application of a plurality of electrical fields
US6294063B1 (en) * 1999-02-12 2001-09-25 Board Of Regents, The University Of Texas System Method and apparatus for programmable fluidic processing
JP2005515058A (en) * 2002-01-04 2005-05-26 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム Wallless channel for fluid path assignment and restriction
US20050148064A1 (en) * 2003-12-29 2005-07-07 Intel Corporation Microfluid molecular-flow fractionator and bioreactor with integrated active/passive diffusion barrier
US20060177815A1 (en) * 2004-11-29 2006-08-10 The Regents Of The University Of California Dielectrophoretic particle sorter

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5653859A (en) * 1993-01-21 1997-08-05 Parton; Adrian Methods of analysis/separation
WO1997034689A1 (en) * 1996-03-18 1997-09-25 University College Of North Wales Apparatus with electrode arrays for carrying out chemical, physical or physico-chemical reactions
US6185084B1 (en) * 1997-10-06 2001-02-06 California Institute Of Technology Electrostatic particle transportation
WO2001005512A1 (en) * 1999-07-20 2001-01-25 University Of Wales, Bangor Dielectrophoretic apparatus & method
US6596143B1 (en) * 2000-09-27 2003-07-22 Aviva Biosciences Corporation Apparatus for switching and manipulating particles and method of use thereof
US20050123992A1 (en) * 2003-12-03 2005-06-09 Palo Alto Research Center Incorporated Concentration and focusing of bio-agents and micron-sized particles using traveling wave grids

Also Published As

Publication number Publication date
EP2052783A1 (en) 2009-04-29
WO2009053889A2 (en) 2009-04-30

Similar Documents

Publication Publication Date Title
WO2009143166A3 (en) Systems, methods, and apparatus for calibrating, controlling, and operating a quantum processor
WO2007110739A3 (en) Method and apparatus for the processing and/or analysis and/or selection of particles, in particular biological particles
JP2012127922A5 (en)
ATE472372T1 (en) HANDLING MAGNETIC OR MAGNETIZABLE OBJECTS USING COMBINED MAGNETOPHORESIS AND DIELECTROPHORESIS
UA111943C2 (en) METHOD AND REACTOR FOR SELECTIVE REMOVAL OF PRODUCTS FROM THE GAS SYSTEM
WO2007088517A3 (en) Apparatus for manipulating, modifying and characterizing particles in a micro channel
WO2006003214A3 (en) Method and apparatus for the separation and quantification of particles
WO2007092643A3 (en) Method and apparatus for generating thermal melting curves in a microfluidic device
WO2010008563A3 (en) Methods and systems for manipulating particles using a fluidized bed
WO2009078307A1 (en) Device and method for separating biological particle contained in liquid flow
WO2011033277A3 (en) Apparatus and method for the manipulation of objects using ultrasound
WO2007084392A3 (en) Electromagnetically actuated valves for use in microfluidic structures
WO2011110831A3 (en) Apparatus and method for separating solids from a solids laden drilling fluid
EP2002880A4 (en) Liquid separation device, flow channel material and process for producing the same
WO2008143279A1 (en) Method for separating carbon nanotubes
EP2044220A4 (en) Systems and methods for real-time pcr
WO2006117676A3 (en) Method for the detection and characterization of microorganisms on a filter
WO2008089244A3 (en) Frequency-addressable apparatus and methods for actuation of liquids
WO2008009433A3 (en) Method and apparatus for reducing metalliferous material to a reduction product
WO2008013813A3 (en) System using disposable self-contained processing module for detecting nucleic acids
WO2007078642A3 (en) Method and apparatus for removing contamination from substrate
WO2007074381A3 (en) Wheel pant device for a vehicle and control method thereof
WO2006113639A3 (en) Method and apparatus for flue gas desulphurization
WO2009027927A3 (en) Dielectrophoretic device for manipulation of particles
WO2010151812A3 (en) Method and apparatus for stopping a spreader

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08842375

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08842375

Country of ref document: EP

Kind code of ref document: A2