WO2009046880A3 - Use of a peptide as a therapeutic agent - Google Patents

Use of a peptide as a therapeutic agent Download PDF

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Publication number
WO2009046880A3
WO2009046880A3 PCT/EP2008/008148 EP2008008148W WO2009046880A3 WO 2009046880 A3 WO2009046880 A3 WO 2009046880A3 EP 2008008148 W EP2008008148 W EP 2008008148W WO 2009046880 A3 WO2009046880 A3 WO 2009046880A3
Authority
WO
WIPO (PCT)
Prior art keywords
disease
peptide
therapeutic agent
trp
leu
Prior art date
Application number
PCT/EP2008/008148
Other languages
French (fr)
Other versions
WO2009046880A2 (en
Inventor
Dorian Bevec
Fabio Cavalli
Vera Cavalli
Gerald Bacher
Original Assignee
Mondobiotech Lab Ag
Dorian Bevec
Fabio Cavalli
Vera Cavalli
Gerald Bacher
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mondobiotech Lab Ag, Dorian Bevec, Fabio Cavalli, Vera Cavalli, Gerald Bacher filed Critical Mondobiotech Lab Ag
Publication of WO2009046880A2 publication Critical patent/WO2009046880A2/en
Publication of WO2009046880A3 publication Critical patent/WO2009046880A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Abstract

The present invention is directed to the use of the combination of the peptide compounds Cyclo(-D-Trp-D-Asp-Pro-D-Val-Leu) and Cyclo(D-Ser-Pro-D-Val-Leu-D- Trp) as a therapeutic combination for prophylaxis and/or treatment of a heart and vascular disease, an infectious disease, a fibrotic disease, an inflammatory disease, a neurodegenerative disease, or an autoimmune disease.
PCT/EP2008/008148 2007-09-11 2008-09-09 Use of a peptide as a therapeutic agent WO2009046880A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EPEP07017764.7 2007-09-11
EP07017764 2007-09-11
EPEP07017751.4 2007-09-11
EP07017751 2007-09-11

Publications (2)

Publication Number Publication Date
WO2009046880A2 WO2009046880A2 (en) 2009-04-16
WO2009046880A3 true WO2009046880A3 (en) 2009-05-28

Family

ID=40445703

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/008148 WO2009046880A2 (en) 2007-09-11 2008-09-09 Use of a peptide as a therapeutic agent

Country Status (1)

Country Link
WO (1) WO2009046880A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114158523A (en) * 2021-08-12 2022-03-11 昆明医科大学 Method for establishing improved rabbit abdominal aortic atherosclerotic plaque model

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05194254A (en) * 1992-01-22 1993-08-03 Banyu Pharmaceut Co Ltd Antihyperlipemia containing endoserine antagonist
WO1993017701A1 (en) * 1992-03-12 1993-09-16 The Administrators Of The Tulane Educational Fund Endothelin receptor-binding peptides
US5820583A (en) * 1995-12-12 1998-10-13 Omeros Medical Systems, Inc. Surgical irrigation solution and method for inhibition of pain and inflammation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05194254A (en) * 1992-01-22 1993-08-03 Banyu Pharmaceut Co Ltd Antihyperlipemia containing endoserine antagonist
WO1993017701A1 (en) * 1992-03-12 1993-09-16 The Administrators Of The Tulane Educational Fund Endothelin receptor-binding peptides
US5820583A (en) * 1995-12-12 1998-10-13 Omeros Medical Systems, Inc. Surgical irrigation solution and method for inhibition of pain and inflammation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 199335, Derwent World Patents Index; AN 1993-278210, XP002520563 *

Also Published As

Publication number Publication date
WO2009046880A2 (en) 2009-04-16

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