WO2009021964A3 - Optical biochip platform with plasmonic structure - Google Patents
Optical biochip platform with plasmonic structure Download PDFInfo
- Publication number
- WO2009021964A3 WO2009021964A3 PCT/EP2008/060621 EP2008060621W WO2009021964A3 WO 2009021964 A3 WO2009021964 A3 WO 2009021964A3 EP 2008060621 W EP2008060621 W EP 2008060621W WO 2009021964 A3 WO2009021964 A3 WO 2009021964A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- optical
- operably
- plasmonic
- plasmonic structure
- biochip platform
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
Abstract
Luminescent sensors which are configured such that operably plasmonic effects contribute to the output of the sensors are described. In a preferred arrangement there is provided a sensor having an optical element which operably effects generation of a luminescence signal for subsequent detection, the optical element being configured such that operably plasmonic effects contribute to at least one of the generation or capture of the luminescence signal. The invention also provides an optical biochip platform with plasmonic structure for detecting fluorescence or other luminescent signals and optical sensor configurations or systems that utilize an optical chip.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95550407P | 2007-08-13 | 2007-08-13 | |
US60/955,504 | 2007-08-13 | ||
US2255908P | 2008-01-22 | 2008-01-22 | |
US61/022,559 | 2008-01-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009021964A2 WO2009021964A2 (en) | 2009-02-19 |
WO2009021964A3 true WO2009021964A3 (en) | 2009-04-16 |
Family
ID=40070823
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2008/060621 WO2009021964A2 (en) | 2007-08-13 | 2008-08-13 | Optical biochip platform with plasmonic structure |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2009021964A2 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2480293A (en) | 2010-05-12 | 2011-11-16 | Univ Dublin City | A luminescence based sensor |
FR2982027B1 (en) | 2011-10-26 | 2014-01-03 | Thibaut Mercey | MICRO-STRUCTURED CHIP FOR RESONANCE ANALYSIS OF SURFACE PLASMONS, ANALYSIS DEVICE COMPRISING THE MICRO-STRUCTURED CHIP AND USE OF SAID DEVICE |
FR2982028B1 (en) * | 2011-10-26 | 2020-02-21 | Aryballe Technologies | MICROSTRUCTURED CHIP COMPRISING CONVEX SURFACES FOR RESONANCE ANALYSIS OF SURFACE PLASMONS, ANALYSIS DEVICE CONTAINING SAID MICROSTRUCTURED CHIP AND USE OF SAID DEVICE |
US20160370289A1 (en) * | 2014-02-26 | 2016-12-22 | Konica Minolta, Inc. | Sensor chip for surface plasmon-field enhanced fluorescence spectroscopy |
WO2016015701A1 (en) | 2014-07-31 | 2016-02-04 | Schebo Biotech Ag | Bioanalysis device, the production thereof and method for detecting bioanalytes by means of the device |
WO2018046689A1 (en) * | 2016-09-08 | 2018-03-15 | Danmarks Tekniske Universitet | A polymeric chip system and uses thereof |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19651935A1 (en) * | 1996-12-14 | 1998-06-18 | Ruckstuhl Thomas | Optical sensor based on evanescent coupling of fluorescent light |
US6090545A (en) * | 1995-03-10 | 2000-07-18 | Meso Scale Technologies, Llc. | Multi-array, multi-specific electrochemiluminescence testing |
US20040113077A1 (en) * | 2002-09-25 | 2004-06-17 | Stefan Franzen | Surface plasmon resonance systems and methods having a variable charge density layer |
US20050009198A1 (en) * | 2001-09-11 | 2005-01-13 | Maccraith Brian | Luminescence-based sensor assembly |
-
2008
- 2008-08-13 WO PCT/EP2008/060621 patent/WO2009021964A2/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6090545A (en) * | 1995-03-10 | 2000-07-18 | Meso Scale Technologies, Llc. | Multi-array, multi-specific electrochemiluminescence testing |
DE19651935A1 (en) * | 1996-12-14 | 1998-06-18 | Ruckstuhl Thomas | Optical sensor based on evanescent coupling of fluorescent light |
US20050009198A1 (en) * | 2001-09-11 | 2005-01-13 | Maccraith Brian | Luminescence-based sensor assembly |
US20040113077A1 (en) * | 2002-09-25 | 2004-06-17 | Stefan Franzen | Surface plasmon resonance systems and methods having a variable charge density layer |
Non-Patent Citations (6)
Title |
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BLUE R ET AL: "Platform for enhanced detection efficiency in luminescence-based sensors", ELECTRONICS LETTERS, IEE STEVENAGE, GB, vol. 41, no. 12, 9 June 2005 (2005-06-09), pages 682 - 684, XP006024192, ISSN: 0013-5194 * |
KRIEG ET AL: "Towards single-molecule DNA sequencing: Assays with low nonspecific adsorption", ANALYTICAL BIOCHEMISTRY, ACADEMIC PRESS INC. NEW YORK, vol. 349, no. 2, 15 February 2006 (2006-02-15), pages 181 - 185, XP005274783, ISSN: 0003-2697 * |
ONDREJ STRANIK ET AL: "Optimization of Nanoparticle Size for Plasmonic Enhancement of Fluorescence", PLASMONICS, KLUWER ACADEMIC PUBLISHERS-PLENUM PUBLISHERS, NE, vol. 2, no. 1, 29 December 2006 (2006-12-29), pages 15 - 22, XP019486272, ISSN: 1557-1963 * |
PALUMBO M ET AL: "Surface plasmon resonance detection of metal ions: layer-by-layer assembly of polyelectrolyte sensing layers on a multichannel chip", IEEE SENSORS JOURNAL IEEE USA, vol. 5, no. 6, December 2005 (2005-12-01), pages 1159 - 1164, XP002515936, ISSN: 1530-437X, Retrieved from the Internet <URL:http://ieeexplore.ieee.org/search/wrapper.jsp?arnumber=1532253> [retrieved on 20090219] * |
STRANIK ET AL: "Plasmonic enhancement of fluorescence for sensor applications", SENSORS AND ACTUATORS B, ELSEVIER SEQUOIA S.A., LAUSANNE, CH, vol. 107, no. 1, 27 May 2005 (2005-05-27), pages 148 - 153, XP005247626, ISSN: 0925-4005 * |
TANG ET AL: "Enzymatically biocatalytic precipitates amplified antibody-antigen interaction for super low level immunoassay: An investigation combined surface plasmon resonance with electrochemistry", BIOSENSORS & BIOELECTRONICS, ELSEVIER SCIENCE PUBLISHERS, BARKING, GB, vol. 23, no. 5, 10 August 2007 (2007-08-10), pages 668 - 674, XP022345922, ISSN: 0956-5663 * |
Also Published As
Publication number | Publication date |
---|---|
WO2009021964A2 (en) | 2009-02-19 |
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