WO2009021964A3 - Optical biochip platform with plasmonic structure - Google Patents

Optical biochip platform with plasmonic structure Download PDF

Info

Publication number
WO2009021964A3
WO2009021964A3 PCT/EP2008/060621 EP2008060621W WO2009021964A3 WO 2009021964 A3 WO2009021964 A3 WO 2009021964A3 EP 2008060621 W EP2008060621 W EP 2008060621W WO 2009021964 A3 WO2009021964 A3 WO 2009021964A3
Authority
WO
WIPO (PCT)
Prior art keywords
optical
operably
plasmonic
plasmonic structure
biochip platform
Prior art date
Application number
PCT/EP2008/060621
Other languages
French (fr)
Other versions
WO2009021964A2 (en
Inventor
Brian Maccraith
Michal Trnavsky
Original Assignee
Univ Dublin City
Brian Maccraith
Michal Trnavsky
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Dublin City, Brian Maccraith, Michal Trnavsky filed Critical Univ Dublin City
Publication of WO2009021964A2 publication Critical patent/WO2009021964A2/en
Publication of WO2009021964A3 publication Critical patent/WO2009021964A3/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/648Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6452Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings

Abstract

Luminescent sensors which are configured such that operably plasmonic effects contribute to the output of the sensors are described. In a preferred arrangement there is provided a sensor having an optical element which operably effects generation of a luminescence signal for subsequent detection, the optical element being configured such that operably plasmonic effects contribute to at least one of the generation or capture of the luminescence signal. The invention also provides an optical biochip platform with plasmonic structure for detecting fluorescence or other luminescent signals and optical sensor configurations or systems that utilize an optical chip.
PCT/EP2008/060621 2007-08-13 2008-08-13 Optical biochip platform with plasmonic structure WO2009021964A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US95550407P 2007-08-13 2007-08-13
US60/955,504 2007-08-13
US2255908P 2008-01-22 2008-01-22
US61/022,559 2008-01-22

Publications (2)

Publication Number Publication Date
WO2009021964A2 WO2009021964A2 (en) 2009-02-19
WO2009021964A3 true WO2009021964A3 (en) 2009-04-16

Family

ID=40070823

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/060621 WO2009021964A2 (en) 2007-08-13 2008-08-13 Optical biochip platform with plasmonic structure

Country Status (1)

Country Link
WO (1) WO2009021964A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2480293A (en) 2010-05-12 2011-11-16 Univ Dublin City A luminescence based sensor
FR2982027B1 (en) 2011-10-26 2014-01-03 Thibaut Mercey MICRO-STRUCTURED CHIP FOR RESONANCE ANALYSIS OF SURFACE PLASMONS, ANALYSIS DEVICE COMPRISING THE MICRO-STRUCTURED CHIP AND USE OF SAID DEVICE
FR2982028B1 (en) * 2011-10-26 2020-02-21 Aryballe Technologies MICROSTRUCTURED CHIP COMPRISING CONVEX SURFACES FOR RESONANCE ANALYSIS OF SURFACE PLASMONS, ANALYSIS DEVICE CONTAINING SAID MICROSTRUCTURED CHIP AND USE OF SAID DEVICE
US20160370289A1 (en) * 2014-02-26 2016-12-22 Konica Minolta, Inc. Sensor chip for surface plasmon-field enhanced fluorescence spectroscopy
WO2016015701A1 (en) 2014-07-31 2016-02-04 Schebo Biotech Ag Bioanalysis device, the production thereof and method for detecting bioanalytes by means of the device
WO2018046689A1 (en) * 2016-09-08 2018-03-15 Danmarks Tekniske Universitet A polymeric chip system and uses thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19651935A1 (en) * 1996-12-14 1998-06-18 Ruckstuhl Thomas Optical sensor based on evanescent coupling of fluorescent light
US6090545A (en) * 1995-03-10 2000-07-18 Meso Scale Technologies, Llc. Multi-array, multi-specific electrochemiluminescence testing
US20040113077A1 (en) * 2002-09-25 2004-06-17 Stefan Franzen Surface plasmon resonance systems and methods having a variable charge density layer
US20050009198A1 (en) * 2001-09-11 2005-01-13 Maccraith Brian Luminescence-based sensor assembly

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6090545A (en) * 1995-03-10 2000-07-18 Meso Scale Technologies, Llc. Multi-array, multi-specific electrochemiluminescence testing
DE19651935A1 (en) * 1996-12-14 1998-06-18 Ruckstuhl Thomas Optical sensor based on evanescent coupling of fluorescent light
US20050009198A1 (en) * 2001-09-11 2005-01-13 Maccraith Brian Luminescence-based sensor assembly
US20040113077A1 (en) * 2002-09-25 2004-06-17 Stefan Franzen Surface plasmon resonance systems and methods having a variable charge density layer

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BLUE R ET AL: "Platform for enhanced detection efficiency in luminescence-based sensors", ELECTRONICS LETTERS, IEE STEVENAGE, GB, vol. 41, no. 12, 9 June 2005 (2005-06-09), pages 682 - 684, XP006024192, ISSN: 0013-5194 *
KRIEG ET AL: "Towards single-molecule DNA sequencing: Assays with low nonspecific adsorption", ANALYTICAL BIOCHEMISTRY, ACADEMIC PRESS INC. NEW YORK, vol. 349, no. 2, 15 February 2006 (2006-02-15), pages 181 - 185, XP005274783, ISSN: 0003-2697 *
ONDREJ STRANIK ET AL: "Optimization of Nanoparticle Size for Plasmonic Enhancement of Fluorescence", PLASMONICS, KLUWER ACADEMIC PUBLISHERS-PLENUM PUBLISHERS, NE, vol. 2, no. 1, 29 December 2006 (2006-12-29), pages 15 - 22, XP019486272, ISSN: 1557-1963 *
PALUMBO M ET AL: "Surface plasmon resonance detection of metal ions: layer-by-layer assembly of polyelectrolyte sensing layers on a multichannel chip", IEEE SENSORS JOURNAL IEEE USA, vol. 5, no. 6, December 2005 (2005-12-01), pages 1159 - 1164, XP002515936, ISSN: 1530-437X, Retrieved from the Internet <URL:http://ieeexplore.ieee.org/search/wrapper.jsp?arnumber=1532253> [retrieved on 20090219] *
STRANIK ET AL: "Plasmonic enhancement of fluorescence for sensor applications", SENSORS AND ACTUATORS B, ELSEVIER SEQUOIA S.A., LAUSANNE, CH, vol. 107, no. 1, 27 May 2005 (2005-05-27), pages 148 - 153, XP005247626, ISSN: 0925-4005 *
TANG ET AL: "Enzymatically biocatalytic precipitates amplified antibody-antigen interaction for super low level immunoassay: An investigation combined surface plasmon resonance with electrochemistry", BIOSENSORS & BIOELECTRONICS, ELSEVIER SCIENCE PUBLISHERS, BARKING, GB, vol. 23, no. 5, 10 August 2007 (2007-08-10), pages 668 - 674, XP022345922, ISSN: 0956-5663 *

Also Published As

Publication number Publication date
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