WO2008153689A4 - Expert system for insulin pump therapy - Google Patents

Expert system for insulin pump therapy Download PDF

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Publication number
WO2008153689A4
WO2008153689A4 PCT/US2008/006449 US2008006449W WO2008153689A4 WO 2008153689 A4 WO2008153689 A4 WO 2008153689A4 US 2008006449 W US2008006449 W US 2008006449W WO 2008153689 A4 WO2008153689 A4 WO 2008153689A4
Authority
WO
WIPO (PCT)
Prior art keywords
rule
insulin pump
patient
information
module
Prior art date
Application number
PCT/US2008/006449
Other languages
French (fr)
Other versions
WO2008153689A1 (en
Inventor
Michael Blomquist
Original Assignee
Smiths Medical Md Inc
Michael Blomquist
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smiths Medical Md Inc, Michael Blomquist filed Critical Smiths Medical Md Inc
Priority to EP20080779626 priority Critical patent/EP2160694A1/en
Priority to JP2010509366A priority patent/JP2010531673A/en
Publication of WO2008153689A1 publication Critical patent/WO2008153689A1/en
Publication of WO2008153689A4 publication Critical patent/WO2008153689A4/en

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B15/00—Systems controlled by a computer
    • G05B15/02—Systems controlled by a computer electric
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N5/00—Computing arrangements using knowledge-based models
    • G06N5/02—Knowledge representation; Symbolic representation
    • G06N5/027—Frames
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/60—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • A61M2005/1726—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure the body parameters being measured at, or proximate to, the infusion site
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/502—User interfaces, e.g. screens or keyboards
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/502—User interfaces, e.g. screens or keyboards
    • A61M2205/507—Head Mounted Displays [HMD]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/52—General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient

Abstract

An apparatus comprising a controller. The controller includes an input/output (I/O) module and a rule module. The I/O module is configured to present a question for a patient when communicatively coupled to a user interface and receive patient information in response to the question via the user interface. The rule module is configured to apply a rule to the patient information and generate a suggested insulin pump setting from application of the rule.

Claims

AMENDED CLAIMS received by the International Bureau on 09 December 2008 (09.12.2008)What is claimed is:
1. A device to generate settings for an insulin pump, the device comprising: a controller including: an input/output (I/O) module configured to: present a question for a patient when communicatively coupled to a user interface; and receive patient information in response to the question via the user interface; a rule module configured to: apply a rule to the patient information; and generate a suggested insulin pump setting from application of the rule; and a rule development module configured to receive an edit to the rule via the I/O module.
2. The device of claim 1, including: a memory communicatively coupled to the controller, wherein the memory is to store parameters associated with an insulin pump initial setup, and wherein the rule module is configured to apply the rule to match the parameters to at least one of patient health information, patient lifestyle information, and patient demographic information to generate a suggested insulin pump initial setup.
3. The device of claim 1 or 2, including a communication port communicatively coupled to the controller, and wherein the I/O module is configured to: present the suggested insulin pump setting using the device via the user interface; present a request for confirmation of the insulin pump setting; and receive a confirmation, and communicate the suggested insulin pump setting to an insulin pump via the communication port when a confirmation is received into the device.
27
4. The device of claim 1, 2, or 3 wherein rule module is configured to generate at least one of a basal rate pattern, a correction factor, and a carbohydrate ratio.
5. The device of claim 1 , 2, 3, or 4 wherein rule module is configured to generate a target blood glucose level.
6. The device of claim 1, 2, 3, 4, or 5 including: a memory communicatively coupled to the controller, wherein the memory is to store a database of food options in association with a known amount of nutrient content, and wherein the rule module is configured to generate, using the patient information, a suggested database of food options for storage in an insulin pump.
7. The device of claim 6, wherein the patient information includes at least one of patient health information, patient lifestyle information, and patient demographic information.
8. The device of claim 1 , wherein the rule development module is configured to: display a logical representation of the rule when the I/O module is communicatively coupled to a user interface that includes a display; and convert a manipulation of the logical representation via the user interface into the edit to the rule.
9. The device of claim 1, 2, 3, 4, 5, 6, or 8 wherein the I/O module is configured to: present an action for the user; and receive blood glucose information, and wherein the rule module is configured to: apply the rule to the blood glucose data; and generate a suggested insulin pump setting from application of the rule.
10. The device of claim 9, wherein the device includes a communication port communicatively coupled to the controller, wherein the controller receives the blood glucose data via the communication port from a second separate device that includes a glucose monitor, and wherein the separate device obtains the blood glucose data during a test executed using an insulin pump.
11. The device of claim 10, wherein the communication port includes a wireless communication port.
12. The device of claim 10, wherein the device includes the insulin pump communicatively coupled to the controller.
13. The device of claim 12, wherein the controller is configured to execute the test, and wherein the test includes at least one of a basal rate test, a carbohydrate ratio test, and a correction factor test.
14. The device of claim 9, including a glucose monitor communicatively coupled to the controller, and wherein the glucose monitor obtains the blood glucose data during a test executed using an insulin pump.
15. The device of claim 14, wherein the device includes an insulin pump communicatively coupled to the controller.
16. The device of claim 15, wherein the controller is configured to execute the test, and wherein the test includes at least one of a basal rate test, a carbohydrate ratio test, and a correction factor test.
17. The device of claim 9, wherein I/O module receives the blood glucose data into the device via the user interface.
18. The device of claim 9, wherein the I/O module is configured to present the question after the blood glucose data is received, and wherein the rule module is configured to generate the suggested insulin pump setting from
29 application of the rule to the blood glucose data and patient information received in response to the question.
19. The device of claim 9, wherein the I/O module is configured to present changes to the diet of the patient.
20. The device of claim 9, wherein the I/O module is configured to present changes to the lifestyle of the patient.
21. The device of claim 9, wherein the controller includes a rule development module to receive an edit to the rule via the I/O module and generate the rule, and wherein the rule module is configured to apply the rule to the patient information and the blood glucose data.
22. The device of claim 1, 2, 3, 4, 5, 6, 8, 9, or 10 including a memory communicatively coupled to the controller, wherein the memory is to store patient information, including at least one of patient health information, patient lifestyle information, and patient demographic information; and wherein rule module is configured to apply the rule to the patient information.
23. An apparatus to automatically generate insulin pump settings, the apparatus comprising: means for presenting a question for a patient using a device; means for receiving patient information into the device in response to the question; means for applying a rule to the patient information; means for generating a suggested insulin pump setting from application of the rule; and means for generating the rule.
24. A method of automatically generating insulin pump settings, method comprising: presenting a question for a diabetic patient using a device; receiving patient information into the device in response to the question;
30 applying a rule to the patient information; generating a suggested insulin pump setting from application of the rule using the device; and receiving user input into a rule editor, included in the device, to generate the rule.
25. The method of claim 24, wherein applying the rule includes matching an insulin pump initial setup to at least one of patient health information, patient lifestyle information, and patient demographic information, and wherein the suggested insulin pump setting includes presenting a suggested insulin pump initial setup.
26. The method of claim 24 or 25, including: presenting the suggested insulin pump setting using the device; presenting a request for confirmation of the insulin pump setting; and programming an insulin pump with the suggested insulin pump setting when a confirmation is received into the device.
27. The method of claim 24, 25, or 26, wherein the suggested insulin pump setting includes at least one of a basal rate pattern, a correction factor, and a carbohydrate ratio.
28. The method of claim 24, 25, 26, or 27, wherein the suggested insulin pump setting includes a target blood glucose level.
29. The method of claim 24, 25, 26, 27, or 28, wherein the suggested insulin pump setting includes a suggested database of food options for storage in an insulin pump, wherein the food options in the database are selected based on at least one of patient health information, patient lifestyle information, and patient demographic information.
30. The method of claim 29, wherein receiving user input includes: receiving user input through a user interface into the rule editor, wherein the user interface includes a display; and
31 displaying a logical representation of the rule during rule editing.
31. The method of claim 24, 25, 26, 27, 28, 29, or 30, including: presenting an action for the patient using the device; receiving blood glucose information into the device; applying the rule to the blood glucose data; and generating a suggested insulin pump setting from application of the rule.
32. The method of claim 31 , including obtaining the blood glucose data during a test executed by an insulin pump.
33. The method of claim 32, wherein the test includes at least one of a basal rate test, a carbohydrate ratio test, and a correction factor test.
34. The method of claim 32, wherein the question is presented after the blood glucose data is received into the device, and wherein the generating includes generating a suggested insulin pump setting from application of the rule to the blood glucose data and patient information received in response to the question.
35. The method of claim 32, wherein the device includes the insulin pump.
36. The method of claim 31 , including communicating the suggested insulin pump setting to an insulin pump when a confirmation is received into the device.
37. The method of claim 31 , wherein the blood glucose data is obtained using a glucose monitor.
38. The method of claim 37, wherein the glucose monitor is included in an insulin pump.
39. The method of claim 37, wherein the glucose monitor is included in the device.
32
40. The method of claim 31 , wherein the blood glucose data is received into the device via a user interface.
41. The method of claim 31 , wherein the action for the patient includes changes to the diet of the patient.
42. The method of claim 31 , wherein the action for the patient includes changes to the lifestyle of the patient.
43. The method of claim 31 , including receiving user input into a rule editor included in the device to generate the rule, wherein the generated rule is applied to the patient information and the blood glucose data.
44. The method of claim 24, 25, 26, 27, 28, 29, or 31 , wherein the patient information includes health information.
45. The method of claim 24, 25, 26, 27, 28, 29, or 31 , wherein the patient information includes lifestyle information.
46. The method of claim 24, 25, 26, 27, 28, 29, or 31 , wherein the patient information includes demographic information.
47. A computer readable medium with instructions therein, which when processed result in a device: presenting a question for a patient; receiving patient information into the device in response to the question; applying a rule to the patient information; and generating a suggested insulin pump setting from application of the rule; and receiving user input into the device to generate the rule.
48. The computer readable medium of claim 47, including instructions, which when processed result in the device: presenting the suggested insulin pump setting;
33 presenting a request for confirmation of the insulin pump setting; and programming an insulin pump with the suggested insulin pump setting when a confirmation is received into the device.
49. The computer readable medium of claim 47 or 48, including instructions, which when processed result in the device: presenting an action for the patient using the device; receiving blood glucose information into the device; applying the rule to the blood glucose data; and generating a suggested insulin pump setting from application of the rule.
50. The computer readable medium of claim 47, 48, or 49, including instructions, which when processed result in the device receiving user input into, a rule editor, included in the device, to generate the rule.
34
PCT/US2008/006449 2007-05-24 2008-05-20 Expert system for insulin pump therapy WO2008153689A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP20080779626 EP2160694A1 (en) 2007-05-24 2008-05-20 Expert system for insulin pump therapy
JP2010509366A JP2010531673A (en) 2007-05-24 2008-05-20 Expert system for insulin pump therapy

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/753,420 2007-05-24
US11/753,420 US7751907B2 (en) 2007-05-24 2007-05-24 Expert system for insulin pump therapy

Publications (2)

Publication Number Publication Date
WO2008153689A1 WO2008153689A1 (en) 2008-12-18
WO2008153689A4 true WO2008153689A4 (en) 2009-02-26

Family

ID=39758848

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/006449 WO2008153689A1 (en) 2007-05-24 2008-05-20 Expert system for insulin pump therapy

Country Status (4)

Country Link
US (9) US7751907B2 (en)
EP (1) EP2160694A1 (en)
JP (1) JP2010531673A (en)
WO (1) WO2008153689A1 (en)

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US8219222B2 (en) 2007-05-24 2012-07-10 Smiths Medical Asd, Inc. Expert system for pump therapy
US8221345B2 (en) 2007-05-30 2012-07-17 Smiths Medical Asd, Inc. Insulin pump based expert system

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