WO2008130607A3 - Wound healing compositions containing keratin biomaterials - Google Patents

Wound healing compositions containing keratin biomaterials Download PDF

Info

Publication number
WO2008130607A3
WO2008130607A3 PCT/US2008/004984 US2008004984W WO2008130607A3 WO 2008130607 A3 WO2008130607 A3 WO 2008130607A3 US 2008004984 W US2008004984 W US 2008004984W WO 2008130607 A3 WO2008130607 A3 WO 2008130607A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions containing
wound healing
healing compositions
containing keratin
keratin
Prior art date
Application number
PCT/US2008/004984
Other languages
French (fr)
Other versions
WO2008130607A2 (en
Inventor
Dyke Mark E Van
Original Assignee
Univ Wake Forest Health Sciences
Dyke Mark E Van
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Wake Forest Health Sciences, Dyke Mark E Van filed Critical Univ Wake Forest Health Sciences
Priority to CA2683015A priority Critical patent/CA2683015C/en
Priority to EP08743024A priority patent/EP2146738A2/en
Priority to CN200880020599A priority patent/CN101730540A/en
Priority to JP2010504088A priority patent/JP5868592B2/en
Priority to AU2008241396A priority patent/AU2008241396B2/en
Publication of WO2008130607A2 publication Critical patent/WO2008130607A2/en
Publication of WO2008130607A3 publication Critical patent/WO2008130607A3/en
Priority to IL201425A priority patent/IL201425A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0047—Specific proteins or polypeptides not covered by groups A61L26/0033 - A61L26/0042
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Abstract

Disclosed are keratin preparations for use in medical applications. Methods of treating wounds are provided, wherein keratin preparations are applied to the wound in a treatment effective amount. Methods of treating burn wounds are also provided. Surgical or paramedic aids are provided, comprising a substrate with keratin preparations provided thereon. Kits comprising keratin derivatives packaged in sterile form are also provided.
PCT/US2008/004984 2006-02-17 2008-04-17 Wound healing compositions containing keratin biomaterials WO2008130607A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CA2683015A CA2683015C (en) 2007-04-17 2008-04-17 Wound healing compositions containing keratin biomaterials
EP08743024A EP2146738A2 (en) 2007-04-17 2008-04-17 Wound healing compositions containing keratin biomaterials
CN200880020599A CN101730540A (en) 2007-04-17 2008-04-17 Wound healing compositions containing keratin biomaterials
JP2010504088A JP5868592B2 (en) 2007-04-17 2008-04-17 Wound healing composition containing keratin biomaterial
AU2008241396A AU2008241396B2 (en) 2006-02-17 2008-04-17 Wound healing compositions containing keratin biomaterials
IL201425A IL201425A0 (en) 2007-04-17 2009-10-11 Wound healing compositions containing keratin biomaterials

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91226507P 2007-04-17 2007-04-17
US60/912,265 2007-04-17

Publications (2)

Publication Number Publication Date
WO2008130607A2 WO2008130607A2 (en) 2008-10-30
WO2008130607A3 true WO2008130607A3 (en) 2009-02-26

Family

ID=39876125

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/004984 WO2008130607A2 (en) 2006-02-17 2008-04-17 Wound healing compositions containing keratin biomaterials

Country Status (7)

Country Link
EP (1) EP2146738A2 (en)
JP (1) JP5868592B2 (en)
CN (1) CN101730540A (en)
AU (1) AU2008241396B2 (en)
CA (1) CA2683015C (en)
IL (1) IL201425A0 (en)
WO (1) WO2008130607A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2791386C (en) * 2010-03-05 2023-10-31 Wake Forest University Health Sciences Keratin gel composition for controlled delivery of a compound
WO2012068376A2 (en) 2010-11-17 2012-05-24 Wake Forest University Health Sciences Keratin compositions for treatment of bone deficiency or injury
WO2013025941A1 (en) 2011-08-17 2013-02-21 Keranetics Llc Low protein percentage gelling compositions
EP2744820B1 (en) 2011-08-17 2018-07-25 Keranetics LLC Methods for extracting keratin proteins
US9827245B2 (en) 2013-03-15 2017-11-28 KeraNetics, LLC Keratin compositions comprising halofuginone
EP3151796A4 (en) 2014-06-04 2018-01-10 Zim Biosciences, Inc. Compositions and methods for improving skin quality
JP6637241B2 (en) * 2015-03-02 2020-01-29 アドバンス株式会社 Method for producing soluble keratein
CN106473945A (en) * 2016-07-21 2017-03-08 北京东方艾美生物技术股份有限公司 A kind of preparation method of keratin facial mask
WO2018220739A1 (en) * 2017-05-31 2018-12-06 株式会社リトル・サイエンティスト Keratin derivative obtainable at high yield, and method of using same
CN112794894B (en) * 2019-10-28 2023-09-26 中国医学科学院药物研究所 Keratin BD-17, its preparation method, its pharmaceutical composition and use
CN112724227B (en) * 2019-10-28 2023-09-26 中国医学科学院药物研究所 Keratin BD-1, its preparation method, its pharmaceutical composition and use

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4570629A (en) * 1982-03-17 1986-02-18 University Of Illinois Foundation Hydrophilic biopolymeric copolyelectrolytes, and biodegradable wound dressing comprising same
WO2000076437A1 (en) * 1999-06-11 2000-12-21 Keraplast Technologies, Ltd. Soluble keratin peptide
US20030228353A1 (en) * 2002-01-28 2003-12-11 Keraplast Technologies, Ltd. Bioactive keratin peptides
WO2007098053A2 (en) * 2006-02-17 2007-08-30 Wake Forest University Health Sciences Coatings and biomedical implants formed from keratin biomaterials

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1213520A (en) * 1982-03-17 1986-11-04 Abe Widra Hydrophilic biopolymeric copolyelectrolytes, and biodegradable dressings comprising same
FR2661414B1 (en) * 1990-04-25 1995-03-24 Michel Jean Pierre PRODUCT BASED ON MODIFIED KERATINS, ITS PREPARATION PROCESS AND ITS APPLICATIONS IN PARTICULAR IN HUMAN OR VETERINARY MEDICINE.
US6270793B1 (en) * 1999-09-13 2001-08-07 Keraplast Technologies, Ltd. Absorbent keratin wound dressing
US6371984B1 (en) * 1999-09-13 2002-04-16 Keraplast Technologies, Ltd. Implantable prosthetic or tissue expanding device
US6544548B1 (en) * 1999-09-13 2003-04-08 Keraplast Technologies, Ltd. Keratin-based powders and hydrogel for pharmaceutical applications
JP2006508027A (en) * 2002-04-10 2006-03-09 ケラプラスト テクノロジーズ， リミテッド Heterogeneous protein networks crosslinked by silicone-containing bonds and methods for producing them

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4570629A (en) * 1982-03-17 1986-02-18 University Of Illinois Foundation Hydrophilic biopolymeric copolyelectrolytes, and biodegradable wound dressing comprising same
WO2000076437A1 (en) * 1999-06-11 2000-12-21 Keraplast Technologies, Ltd. Soluble keratin peptide
US20030228353A1 (en) * 2002-01-28 2003-12-11 Keraplast Technologies, Ltd. Bioactive keratin peptides
WO2007098053A2 (en) * 2006-02-17 2007-08-30 Wake Forest University Health Sciences Coatings and biomedical implants formed from keratin biomaterials

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
19000101, 1 January 1900 (1900-01-01), XP009109568 *

Also Published As

Publication number Publication date
JP5868592B2 (en) 2016-02-24
AU2008241396A1 (en) 2008-10-30
CA2683015C (en) 2016-11-08
AU2008241396B2 (en) 2014-06-19
IL201425A0 (en) 2010-05-31
WO2008130607A2 (en) 2008-10-30
CA2683015A1 (en) 2008-10-30
EP2146738A2 (en) 2010-01-27
JP2010524943A (en) 2010-07-22
CN101730540A (en) 2010-06-09

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