WO2008124165A9 - Self-assembling nanoparticle drug delivery system - Google Patents
Self-assembling nanoparticle drug delivery system Download PDFInfo
- Publication number
- WO2008124165A9 WO2008124165A9 PCT/US2008/004585 US2008004585W WO2008124165A9 WO 2008124165 A9 WO2008124165 A9 WO 2008124165A9 US 2008004585 W US2008004585 W US 2008004585W WO 2008124165 A9 WO2008124165 A9 WO 2008124165A9
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- self
- delivery system
- drug delivery
- nanoparticle drug
- assembling nanoparticle
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5176—Compounds of unknown constitution, e.g. material from plants or animals
- A61K9/5184—Virus capsids or envelopes enclosing drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
- A61K47/6925—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a microcapsule, nanocapsule, microbubble or nanobubble
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08742685A EP2134740A2 (en) | 2007-04-09 | 2008-04-09 | Self-assembling nanoparticle drug delivery system |
CA002683063A CA2683063A1 (en) | 2007-04-09 | 2008-04-09 | Self-assembling nanoparticle drug delivery system |
AU2008236566A AU2008236566A1 (en) | 2007-04-09 | 2008-04-09 | Self-assembling nanoparticle drug delivery system |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US91070407P | 2007-04-09 | 2007-04-09 | |
US60/910,704 | 2007-04-09 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2008124165A2 WO2008124165A2 (en) | 2008-10-16 |
WO2008124165A3 WO2008124165A3 (en) | 2008-12-04 |
WO2008124165A9 true WO2008124165A9 (en) | 2009-04-30 |
Family
ID=39730629
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2008/004585 WO2008124165A2 (en) | 2007-04-09 | 2008-04-09 | Self-assembling nanoparticle drug delivery system |
Country Status (5)
Country | Link |
---|---|
US (2) | US20090226525A1 (en) |
EP (1) | EP2134740A2 (en) |
AU (1) | AU2008236566A1 (en) |
CA (1) | CA2683063A1 (en) |
WO (1) | WO2008124165A2 (en) |
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DK2359869T3 (en) * | 2001-12-17 | 2019-04-15 | Univ Pennsylvania | Sequences of adeno-associated virus (AAV) serotype 8, vectors containing these, and uses thereof |
DE60335186D1 (en) * | 2002-06-20 | 2011-01-13 | Cytos Biotechnology Ag | PACKAGED VIRUS PARTICLES IN COMBINATION WITH CPG FOR USE AS ADJUVANTIES WITH ALLERGENS. MANUFACTURING METHOD AND USE |
US7148342B2 (en) * | 2002-07-24 | 2006-12-12 | The Trustees Of The University Of Pennyslvania | Compositions and methods for sirna inhibition of angiogenesis |
AU2003287526A1 (en) * | 2002-11-06 | 2004-06-03 | Protein-stabilized liposomal formulations of pharmaceutical agents | |
JP2004175665A (en) * | 2002-11-22 | 2004-06-24 | Japan Science & Technology Agency | Protein hollow nanoparticle and drug using the same |
DK1585548T3 (en) * | 2002-12-09 | 2018-09-03 | Abraxis Bioscience Llc | COMPOSITIONS AND PROCEDURES FOR THE DELIVERY OF PHARMACOLOGICAL AGENTS |
AU2004282563A1 (en) * | 2003-10-15 | 2005-04-28 | Board Of Regents, The University Of Texas System | Viral fibers |
EP1773303A2 (en) * | 2004-05-25 | 2007-04-18 | Chimeracore, Inc. | Self-assembling nanoparticle drug delivery system |
CA2572129A1 (en) * | 2004-07-01 | 2006-01-12 | The Circle For The Promotion Of Science And Engineering | Viral particle-like construct and method of forming the same under physiological conditions |
GB0416487D0 (en) * | 2004-07-23 | 2004-08-25 | Isis Innovation | Modified virus |
CN101056539B (en) * | 2004-09-09 | 2012-12-12 | 综合医院公司 | Modulating phosphatase activity in cardiac cells |
EP1799251A2 (en) * | 2004-09-17 | 2007-06-27 | Chr. Hansen A/S | Chimeric phage-derived particles, methods for their production and use |
US20070258889A1 (en) * | 2005-11-09 | 2007-11-08 | Montana State University | Novel nanoparticles and use thereof |
DE602007005366D1 (en) * | 2006-04-07 | 2010-04-29 | Chimeros Inc | COMPOSITIONS AND METHOD FOR THE TREATMENT OF B-CELL MALIGNOMES |
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2008
- 2008-04-09 WO PCT/US2008/004585 patent/WO2008124165A2/en active Application Filing
- 2008-04-09 CA CA002683063A patent/CA2683063A1/en not_active Abandoned
- 2008-04-09 AU AU2008236566A patent/AU2008236566A1/en not_active Abandoned
- 2008-04-09 EP EP08742685A patent/EP2134740A2/en not_active Withdrawn
- 2008-04-09 US US12/082,154 patent/US20090226525A1/en not_active Abandoned
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2012
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EP2134740A2 (en) | 2009-12-23 |
AU2008236566A1 (en) | 2008-10-16 |
WO2008124165A2 (en) | 2008-10-16 |
US20140010885A1 (en) | 2014-01-09 |
US20090226525A1 (en) | 2009-09-10 |
WO2008124165A3 (en) | 2008-12-04 |
CA2683063A1 (en) | 2008-10-16 |
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