WO2008103377A3 - In vivo hydraulic fixation including bio-rivets using biocompatible expandable fibers - Google Patents

In vivo hydraulic fixation including bio-rivets using biocompatible expandable fibers Download PDF

Info

Publication number
WO2008103377A3
WO2008103377A3 PCT/US2008/002230 US2008002230W WO2008103377A3 WO 2008103377 A3 WO2008103377 A3 WO 2008103377A3 US 2008002230 W US2008002230 W US 2008002230W WO 2008103377 A3 WO2008103377 A3 WO 2008103377A3
Authority
WO
WIPO (PCT)
Prior art keywords
rivets
including bio
fixation including
hydraulic fixation
expandable fibers
Prior art date
Application number
PCT/US2008/002230
Other languages
French (fr)
Other versions
WO2008103377A2 (en
Inventor
Thomas J. Koob
Douglas Pringle
Original Assignee
Shriners Hospitals For Children
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shriners Hospitals For Children filed Critical Shriners Hospitals For Children
Priority to EP08725823A priority Critical patent/EP2131880B1/en
Priority to AU2008219006A priority patent/AU2008219006B2/en
Priority to CA2678821A priority patent/CA2678821C/en
Publication of WO2008103377A2 publication Critical patent/WO2008103377A2/en
Publication of WO2008103377A3 publication Critical patent/WO2008103377A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/08—Muscles; Tendons; Ligaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/08—Muscles; Tendons; Ligaments
    • A61F2/0811—Fixation devices for tendons or ligaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/06—Measuring instruments not otherwise provided for
    • A61B2090/064—Measuring instruments not otherwise provided for for measuring force, pressure or mechanical tension
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/08—Muscles; Tendons; Ligaments
    • A61F2/0811—Fixation devices for tendons or ligaments
    • A61F2002/0817—Structure of the anchor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/08—Muscles; Tendons; Ligaments
    • A61F2/0811—Fixation devices for tendons or ligaments
    • A61F2002/0817—Structure of the anchor
    • A61F2002/0823—Modular anchors comprising a plurality of separate parts
    • A61F2002/0835—Modular anchors comprising a plurality of separate parts with deformation of anchor parts, e.g. expansion of dowel by set screw
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/08—Muscles; Tendons; Ligaments
    • A61F2/0811—Fixation devices for tendons or ligaments
    • A61F2002/0847—Mode of fixation of anchor to tendon or ligament
    • A61F2002/087—Anchor integrated into tendons, e.g. bone blocks, integrated rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/08—Muscles; Tendons; Ligaments
    • A61F2/0811—Fixation devices for tendons or ligaments
    • A61F2002/0876—Position of anchor in respect to the bone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/08—Muscles; Tendons; Ligaments
    • A61F2/0811—Fixation devices for tendons or ligaments
    • A61F2002/0876—Position of anchor in respect to the bone
    • A61F2002/0882—Anchor in or on top of a bone tunnel, i.e. a hole running through the entire bone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/08—Muscles; Tendons; Ligaments
    • A61F2/0811—Fixation devices for tendons or ligaments
    • A61F2002/0876—Position of anchor in respect to the bone
    • A61F2002/0888—Anchor in or on a blind hole or on the bone surface without formation of a tunnel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0061—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof swellable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0004—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof adjustable
    • A61F2250/001—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof adjustable for adjusting a diameter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/10—Materials or treatment for tissue regeneration for reconstruction of tendons or ligaments

Abstract

The disclosure describes implantable medical products, that include dry or partially hydrated biocompatible constructs comprising collagen fibers configured to expand in situ after implantation to frictionally engage a bone tunnel wall to thereby affix the construct in the bone tunnel.
PCT/US2008/002230 2007-02-20 2008-02-20 In vivo hydraulic fixation including bio-rivets using biocompatible expandable fibers WO2008103377A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP08725823A EP2131880B1 (en) 2007-02-20 2008-02-20 In vivo hydraulic fixation including bio-rivets using biocompatible expandable fibers
AU2008219006A AU2008219006B2 (en) 2007-02-20 2008-02-20 In vivo hydraulic fixation including bio-rivets using biocompatible expandable fibers
CA2678821A CA2678821C (en) 2007-02-20 2008-02-20 In vivo hydraulic fixation including bio-rivets using biocompatible expandable fibers

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89067907P 2007-02-20 2007-02-20
US60/890,679 2007-02-20

Publications (2)

Publication Number Publication Date
WO2008103377A2 WO2008103377A2 (en) 2008-08-28
WO2008103377A3 true WO2008103377A3 (en) 2009-09-17

Family

ID=39707351

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/002230 WO2008103377A2 (en) 2007-02-20 2008-02-20 In vivo hydraulic fixation including bio-rivets using biocompatible expandable fibers

Country Status (5)

Country Link
US (4) US8858633B2 (en)
EP (1) EP2131880B1 (en)
AU (1) AU2008219006B2 (en)
CA (1) CA2678821C (en)
WO (1) WO2008103377A2 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7899533B2 (en) * 2005-10-25 2011-03-01 Medtronic, Inc. System and method of AV interval selection in an implantable medical device
CA2921678C (en) 2006-12-27 2018-04-24 Shriners Hospitals For Children Methods of making high-strength ndga polymerized collagen fibers and related collagen-prep methods, medical devices and constructs
US9681869B2 (en) 2008-02-22 2017-06-20 Mimedx Group, Inc. Biostaples suitable for wrist, hand and other ligament replacements or repairs
WO2009139871A2 (en) 2008-05-16 2009-11-19 Mimedx, Inc. Medical constructs of twisted lengths of collagen fibers and methods of making same
CA2976265C (en) 2008-10-09 2019-03-19 Mimedx Group, Inc. Methods of making collagen fiber medical constructs and related medical constructs, including nerve guides and patches
JP5457544B2 (en) * 2009-03-31 2014-04-02 アイエムディーエス コーポレイション Double bundle ACL repair
EP2571548B1 (en) * 2010-05-17 2018-04-18 MiMedx Group, Inc. Compressible tubes for placing implants and related medical kits and methods of using same
EP2683864B1 (en) * 2011-03-08 2016-08-17 MiMedx Group, Inc. Collagen fiber ribbons with integrated fixation sutures and methods of making the same
US9694106B2 (en) 2011-07-11 2017-07-04 Mimedx Group, Inc. Synthetic collagen threads for cosmetic uses including skin wrinkle treatments and associated methods
US8968402B2 (en) 2011-10-18 2015-03-03 Arthrocare Corporation ACL implants, instruments, and methods
EP2773388A4 (en) 2011-11-02 2015-07-15 Mimedx Group Inc Implantable collagen devices and related methods and systems of making same
US8946163B2 (en) 2012-11-19 2015-02-03 Mimedx Group, Inc. Cross-linked collagen comprising metallic anticancer agents
US9155799B2 (en) 2012-11-19 2015-10-13 Mimedx Group, Inc. Cross-linked collagen with at least one bound antimicrobial agent for in vivo release of the agent
US8940684B2 (en) 2012-11-19 2015-01-27 Mimedx Group, Inc. Cross-linked collagen comprising an antifungal agent
US10029030B2 (en) 2013-03-15 2018-07-24 Mimedx Group, Inc. Molded placental tissue compositions and methods of making and using the same
US10335433B2 (en) 2013-04-10 2019-07-02 Mimedx Group, Inc. NDGA polymers and metal complexes thereof
US9446142B2 (en) 2013-05-28 2016-09-20 Mimedx Group, Inc. Polymer chelator conjugates
EP3038630B1 (en) 2013-08-30 2020-03-18 MIMEDX Group Inc. Micronized placental compositions comprising a chelator
US9925035B2 (en) * 2014-05-30 2018-03-27 Oregon State University Implanted passive engineering mechanisms and methods for their use and manufacture
US10524895B2 (en) * 2014-10-10 2020-01-07 Orthocell Limited Collagen construct and method for producing the collagen construct
US10085830B2 (en) * 2016-05-13 2018-10-02 Medos International Sarl Device, system, and method for delivery of a tissue fixation device
CN108125731A (en) * 2017-12-26 2018-06-08 复旦大学附属华山医院 Ankle-joint artificial ligament
US11583609B2 (en) 2018-08-08 2023-02-21 Mimedx Group, Inc. Collagen constructs and methods of making the same
US11096776B2 (en) 2019-02-07 2021-08-24 Biorez, Inc. Composite scaffold for the repair, reconstruction, and regeneration of soft tissues
CN110585570B (en) * 2019-09-17 2022-06-14 北京中杰瑞康科技有限公司 Liquid-absorbing expansion self-adaptive and antibacterial dilating cervical dilator and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996014095A1 (en) * 1994-11-07 1996-05-17 The University Of Medicine And Dentistry Of New Jersey Synthetic collagen orthopaedic structures such as grafts, tendons and other structures
CA2285161A1 (en) * 1999-10-06 2001-04-06 1218122 Ontario Inc. In vitro cultured ligament tissue and method of making same

Family Cites Families (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1104051A (en) 1963-10-16 1968-02-21 Klinger Mfg Co Ltd Improvements in or relating to false twisting apparatus
GB2084468B (en) 1980-09-25 1984-06-06 South African Inventions Surgical implant
US4837285A (en) 1984-03-27 1989-06-06 Medimatrix Collagen matrix beads for soft tissue repair
US4792336A (en) 1986-03-03 1988-12-20 American Cyanamid Company Flat braided ligament or tendon implant device having texturized yarns
US5263984A (en) 1987-07-20 1993-11-23 Regen Biologics, Inc. Prosthetic ligaments
US5078744A (en) * 1987-09-04 1992-01-07 Bio-Products, Inc. Method of using tendon/ligament substitutes composed of long, parallel, non-antigenic tendon/ligament fibers
ATE95399T1 (en) 1987-10-30 1993-10-15 Howmedica DEVICE FOR RESTORING A TENDOOR OR LANDAGE.
US4883486A (en) 1988-05-31 1989-11-28 Indu Kapadia Prosthetic ligament
US5521087A (en) * 1989-05-10 1996-05-28 Massachusetts Institute Of Technology Method for producing oriented connective tissue cells in a ligament configuration
US5106949A (en) 1989-09-15 1992-04-21 Organogenesis, Inc. Collagen compositions and methods for preparation thereof
US5378469A (en) 1990-04-06 1995-01-03 Organogenesis, Inc. Collagen threads
US5256418A (en) 1990-04-06 1993-10-26 Organogenesis, Inc. Collagen constructs
US5656605A (en) 1994-01-26 1997-08-12 Institute Of Molecular Biology, Inc. Device to promote drug-induced nerve regeneration
US5713374A (en) 1995-02-10 1998-02-03 The Hospital For Joint Diseases Orthopaedic Institute Fixation method for the attachment of wound repair materials to cartilage defects
US5900245A (en) 1996-03-22 1999-05-04 Focal, Inc. Compliant tissue sealants
US5718012A (en) 1996-05-28 1998-02-17 Organogenesis, Inc. Method of strength enhancement of collagen constructs
US5718717A (en) * 1996-08-19 1998-02-17 Bonutti; Peter M. Suture anchor
TW528600B (en) 1996-11-20 2003-04-21 Yasuhiko Shimizu Artificial neural canal
TW501934B (en) 1996-11-20 2002-09-11 Tapic Int Co Ltd Collagen material and process for making the same
US6083522A (en) * 1997-01-09 2000-07-04 Neucoll, Inc. Devices for tissue repair and methods for preparation and use thereof
US5814328A (en) * 1997-01-13 1998-09-29 Gunasekaran; Subramanian Preparation of collagen using papain and a reducing agent
WO1998054224A1 (en) 1997-05-28 1998-12-03 Tapic International Co., Ltd. Collagen gel
JPH1122816A (en) * 1997-06-30 1999-01-26 Aisin Seiki Co Ltd Speed change control device for synchromesh transmission
US6245103B1 (en) 1997-08-01 2001-06-12 Schneider (Usa) Inc Bioabsorbable self-expanding stent
US6224630B1 (en) * 1998-05-29 2001-05-01 Advanced Bio Surfaces, Inc. Implantable tissue repair device
WO1999063908A1 (en) 1998-06-10 1999-12-16 Tapic International Co., Ltd. Artificial neural tube
EP1098024A4 (en) 1998-06-11 2008-04-02 Yasuhiko Shimizu Collagen material and process for producing the same
US20020165611A1 (en) 1998-12-22 2002-11-07 Robert-Jan Enzerink Graft material convenience package
US6592623B1 (en) 1999-08-31 2003-07-15 Virginia Commonwealth University Intellectual Property Foundation Engineered muscle
US7615373B2 (en) 1999-02-25 2009-11-10 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed collagen and tissue engineering
US6964685B2 (en) 1999-06-22 2005-11-15 The Brigham And Women's Hospital, Inc. Biologic replacement for fibrin clot
CN1206393C (en) 1999-07-14 2005-06-15 钟渊化学工业株式会社 Regenerated collagen fiber with excellent heat resistance
US6936072B2 (en) * 1999-08-18 2005-08-30 Intrinsic Therapeutics, Inc. Encapsulated intervertebral disc prosthesis and methods of manufacture
US6645247B2 (en) * 1999-10-08 2003-11-11 Bret A. Ferree Supplementing engineered annulus tissues with autograft of allograft tendons
US6893462B2 (en) * 2000-01-11 2005-05-17 Regeneration Technologies, Inc. Soft and calcified tissue implants
US6292697B1 (en) 2000-02-15 2001-09-18 Medtronic, Inc. Testing sterile packaged components of an implantable medical device prior to chronic implantation
AR027685A1 (en) * 2000-03-22 2003-04-09 Synthes Ag METHOD AND METHOD FOR CARRYING OUT
JP4452426B2 (en) 2000-03-24 2010-04-21 ドレクセル ユニバーシティー Ligament replacement structure and manufacturing method thereof
US6565960B2 (en) 2000-06-01 2003-05-20 Shriners Hospital Of Children Polymer composite compositions
US6692528B2 (en) * 2000-11-09 2004-02-17 The Polymer Technology Group Incorporated Devices that change size/shape via osmotic pressure
US6752831B2 (en) 2000-12-08 2004-06-22 Osteotech, Inc. Biocompatible osteogenic band for repair of spinal disorders
DE10104658A1 (en) * 2001-02-02 2002-10-02 Aesculap Ag & Co Kg Implant for fixing a tendoplasty in a channel in the knee region of the tibia and/or femur comprises fixing the tendoplasty under tension in the channel by relative movement between a bearing element and a connecting element
US20040110439A1 (en) 2001-04-20 2004-06-10 Chaikof Elliot L Native protein mimetic fibers, fiber networks and fabrics for medical use
US6902932B2 (en) 2001-11-16 2005-06-07 Tissue Regeneration, Inc. Helically organized silk fibroin fiber bundles for matrices in tissue engineering
US6730124B2 (en) * 2002-03-08 2004-05-04 Musculoskeletal Transplant Foundation Bone-tendon-bone assembly with cancellous allograft bone block
US7514249B2 (en) 2002-04-18 2009-04-07 The University Of Florida Research Foundation, Inc. Biomimetic organic/inorganic composites
US20030230316A1 (en) 2002-06-18 2003-12-18 Glucksman Dov Z. Battery operated hair braider
US7309359B2 (en) * 2003-08-21 2007-12-18 Warsaw Orthopedic, Inc. Allogenic/xenogenic implants and methods for augmenting or repairing intervertebral discs
US7090690B2 (en) * 2002-11-19 2006-08-15 Arthrocare Corporation Devices and methods for repairing soft tissue
US7135040B2 (en) 2002-12-23 2006-11-14 Agency For Science, Technology And Research Medical guide tubes
US8226715B2 (en) 2003-06-30 2012-07-24 Depuy Mitek, Inc. Scaffold for connective tissue repair
EP1682161A4 (en) 2003-10-29 2011-12-07 Gentis Inc Polymerizable emulsions for tissue engineering
FR2865380B1 (en) 2004-01-23 2006-03-03 L A R S Laboratoire D Applic E METHOD FOR ATTACHING TRACTION WIRES TO THE END OF A PROTHETIC LIGAMENT
US20060095134A1 (en) * 2004-10-28 2006-05-04 Sdgi Holdings, Inc. Materials, devices and methods for implantation of transformable implants
US7354627B2 (en) 2004-12-22 2008-04-08 Depuy Products, Inc. Method for organizing the assembly of collagen fibers and compositions formed therefrom
WO2006099332A2 (en) 2005-03-11 2006-09-21 Wake Forest University Health Sciences Production of tissue engineered digits and limbs
US8048446B2 (en) 2005-05-10 2011-11-01 Drexel University Electrospun blends of natural and synthetic polymer fibers as tissue engineering scaffolds
CA2656044C (en) 2006-06-22 2015-10-20 University Of South Florida Collagen scaffolds, medical implants with same and methods of use
US8093027B2 (en) 2006-09-13 2012-01-10 University Of South Florida Method for producing biocomposite comprising collagen and polymer
US20100129656A1 (en) 2006-10-05 2010-05-27 Technion Research & Develpment Foundation Ltd Microtubes and methods of producing same
CA2921678C (en) 2006-12-27 2018-04-24 Shriners Hospitals For Children Methods of making high-strength ndga polymerized collagen fibers and related collagen-prep methods, medical devices and constructs
US9681869B2 (en) 2008-02-22 2017-06-20 Mimedx Group, Inc. Biostaples suitable for wrist, hand and other ligament replacements or repairs
WO2009139871A2 (en) 2008-05-16 2009-11-19 Mimedx, Inc. Medical constructs of twisted lengths of collagen fibers and methods of making same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996014095A1 (en) * 1994-11-07 1996-05-17 The University Of Medicine And Dentistry Of New Jersey Synthetic collagen orthopaedic structures such as grafts, tendons and other structures
CA2285161A1 (en) * 1999-10-06 2001-04-06 1218122 Ontario Inc. In vitro cultured ligament tissue and method of making same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KOOB T J ET AL: "Material properties of polymerized NDGA-collagen composite fibers: development of biologically based tendon constructs", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 23, no. 1, 1 January 2002 (2002-01-01), pages 203 - 212, XP004322636, ISSN: 0142-9612 *

Also Published As

Publication number Publication date
US20140379081A1 (en) 2014-12-25
US20080200992A1 (en) 2008-08-21
EP2131880A2 (en) 2009-12-16
CA2678821C (en) 2015-12-01
US9393105B2 (en) 2016-07-19
AU2008219006B2 (en) 2013-04-18
US9888996B2 (en) 2018-02-13
US20180168797A1 (en) 2018-06-21
EP2131880B1 (en) 2012-08-08
US8858633B2 (en) 2014-10-14
CA2678821A1 (en) 2008-08-28
US20160287377A1 (en) 2016-10-06
WO2008103377A2 (en) 2008-08-28
AU2008219006A1 (en) 2008-08-28

Similar Documents

Publication Publication Date Title
WO2008103377A3 (en) In vivo hydraulic fixation including bio-rivets using biocompatible expandable fibers
WO2009105246A3 (en) Biostaples suitable for wrist, hand and other ligament replacements or repairs
EP1895950A4 (en) Human implantable tissue expander
EP2166989A4 (en) Implantable mesh for musculoskeletal trauma, orthopedic reconstruction and soft tissue repair
EP2129330A4 (en) Human implantable tissue expander
WO2008016919A3 (en) Mastopexy and breast reconstruction prostheses and method
ZA201001118B (en) Prosthesis for promoting the in vivo reconstruction of a hollow organ or a portion of a hollow organ
IL200363A0 (en) In-vivo biodegradable medical implant
WO2009141732A3 (en) Polyurethane foam for use in medical implants
WO2006076416A3 (en) Three dimensional cell protector/pore architecture formation for bone and tissue constructs
FR2871367B1 (en) PROSTHETIC EXPANSIBLE BONE IMPLANT
EP1613252A4 (en) Percutaneously implantable medical device configured to promote tissue ingrowth
EP1874235A4 (en) Surgically implantable prosthetic system
EP2034955A4 (en) Collagen scaffolds, medical implants with same and methods of use
EP1737506A4 (en) Implant scaffold combined with autologous or allogenic tissue
HK1150526A1 (en) Implantable tissue connector
WO2008130989A3 (en) Prosthetic implants
WO2009011882A3 (en) Endoscopic implant system and method
BRPI0906750B8 (en) Porous biocompatible polymeric material and methods
WO2009102452A3 (en) Compositions and methods for implantation of adipose tissue and adipose tissue products
BRPI0822920A2 (en) Medical Implant and Implantation Method
EP2204197A4 (en) Biocompatible and low-wear material, artificial joint using the same and method of producing the same
EP3659551C0 (en) Implantable tissue connector
WO2010120911A3 (en) Minimally invasive expandable contained vertebral implant and method
EP1943336A4 (en) Reconstructed living adipose tissue

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08725823

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 2678821

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2008219006

Country of ref document: AU

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2008725823

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2008219006

Country of ref document: AU

Date of ref document: 20080220

Kind code of ref document: A