WO2008100498A3 - Treatment of inflammatory diseases using placental stem cells - Google Patents
Treatment of inflammatory diseases using placental stem cells Download PDFInfo
- Publication number
- WO2008100498A3 WO2008100498A3 PCT/US2008/001831 US2008001831W WO2008100498A3 WO 2008100498 A3 WO2008100498 A3 WO 2008100498A3 US 2008001831 W US2008001831 W US 2008001831W WO 2008100498 A3 WO2008100498 A3 WO 2008100498A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- stem cells
- treatment
- placental stem
- inflammatory diseases
- disease
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
- C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/36—Lipids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/135—Platelet-derived growth factor [PDGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/39—Steroid hormones
Abstract
Priority Applications (25)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN200880011754XA CN101657206B (en) | 2007-02-12 | 2008-02-12 | Treatment of inflammatory diseases using placental stem cells |
MX2013009114A MX349225B (en) | 2007-02-12 | 2008-02-12 | Treatment of inflammatory diseases using placental stem cells. |
CA2677397A CA2677397C (en) | 2007-02-12 | 2008-02-12 | Treatment of inflammatory diseases using placental stem cells |
EP08725458.7A EP2120977B1 (en) | 2007-02-12 | 2008-02-12 | Treatment of inflammatory diseases using placental stem cells |
NZ578819A NZ578819A (en) | 2007-02-12 | 2008-02-12 | Treatment of inflammatory diseases using placental stem cells |
DK08725458.7T DK2120977T3 (en) | 2007-02-12 | 2008-02-12 | Treatment of inflammatory diseases using placental stem cells |
JP2009549140A JP5979811B2 (en) | 2007-02-12 | 2008-02-12 | Treatment of inflammatory diseases using placental stem cells |
KR1020097018749A KR101569168B1 (en) | 2007-02-12 | 2008-02-12 | Treatment of inflammatory diseases using placental stem cells |
AU2008216749A AU2008216749B2 (en) | 2007-02-12 | 2008-02-12 | Treatment of inflammatory diseases using placental stem cells |
MX2009008563A MX2009008563A (en) | 2007-02-12 | 2008-02-12 | Treatment of inflammatory diseases using placental stem cells. |
ES08725458T ES2425181T3 (en) | 2007-02-12 | 2008-02-12 | Treatment of inflammatory diseases using placenta stem cells |
MEP-2013-92A ME01562B (en) | 2007-02-12 | 2008-02-12 | Treatment of inflammatory diseases using placental stem cells |
KR1020157005148A KR20150039214A (en) | 2007-02-12 | 2008-02-12 | Treatment of inflammatory diseases using placental stem cells |
RS20130344A RS52921B (en) | 2007-02-12 | 2008-02-12 | Treatment of inflammatory diseases using placental stem cells |
EP20177748.9A EP3763376A1 (en) | 2007-02-12 | 2008-02-12 | Treatment of inflammatory diseases using placental stem cells |
SI200831012T SI2120977T1 (en) | 2007-02-12 | 2008-02-12 | Treatment of inflammatory diseases using placental stem cells |
PL08725458T PL2120977T3 (en) | 2007-02-12 | 2008-02-12 | Treatment of inflammatory diseases using placental stem cells |
ZA2009/05376A ZA200905376B (en) | 2007-02-12 | 2009-07-31 | Treatment of inflammatory diseases using placental stem cells |
IL200338A IL200338A (en) | 2007-02-12 | 2009-08-11 | Use of placental stem cells for the preparation of medicaments for treatment of inflammatory diseases |
HK10103211.5A HK1135328A1 (en) | 2007-02-12 | 2010-03-29 | Treatment of inflammatory diseases using placental stem cells |
HRP20130765AT HRP20130765T1 (en) | 2007-02-12 | 2013-08-12 | Treatment of inflammatory diseases using placental stem cells |
IL233376A IL233376A (en) | 2007-02-12 | 2014-06-25 | Compositions for treatment of scleroderma or mycosis fungoides containing cd200+, cd10+, cd105+ and cd34- placental stem cells |
IL233377A IL233377A (en) | 2007-02-12 | 2014-06-25 | Matrix comprising placental stem cells for treatment of inflammatory diseases |
IL248463A IL248463A0 (en) | 2007-02-12 | 2016-10-25 | Treatment of inflammatory diseases using placental stem cells |
IL262075A IL262075B (en) | 2007-02-12 | 2018-10-02 | Treatment of inflammatory diseases using placental stem cells |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US90106707P | 2007-02-12 | 2007-02-12 | |
US60/901,067 | 2007-02-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008100498A2 WO2008100498A2 (en) | 2008-08-21 |
WO2008100498A3 true WO2008100498A3 (en) | 2008-10-30 |
Family
ID=39618996
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2008/001831 WO2008100498A2 (en) | 2007-02-12 | 2008-02-12 | Treatment of inflammatory diseases using placental stem cells |
Country Status (22)
Country | Link |
---|---|
US (7) | US8460650B2 (en) |
EP (6) | EP3763376A1 (en) |
JP (2) | JP5979811B2 (en) |
KR (2) | KR101569168B1 (en) |
CN (3) | CN103356711A (en) |
AU (1) | AU2008216749B2 (en) |
CA (1) | CA2677397C (en) |
CY (1) | CY1114301T1 (en) |
DK (1) | DK2120977T3 (en) |
ES (1) | ES2425181T3 (en) |
HK (2) | HK1135328A1 (en) |
HR (1) | HRP20130765T1 (en) |
IL (5) | IL200338A (en) |
ME (1) | ME01562B (en) |
MX (2) | MX349225B (en) |
NZ (3) | NZ612888A (en) |
PL (1) | PL2120977T3 (en) |
PT (1) | PT2120977E (en) |
RS (1) | RS52921B (en) |
SI (1) | SI2120977T1 (en) |
WO (1) | WO2008100498A2 (en) |
ZA (2) | ZA200905376B (en) |
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