WO2008058820A1

WO2008058820A1 - Two-phase mouthwash

Info

Publication number: WO2008058820A1
Application number: PCT/EP2007/060815
Authority: WO
Inventors: Wilfried Howorka; Ullrich Bernecker; Adolf Peter Barth
Original assignee: Henkel Ag & Co. Kgaa
Priority date: 2006-11-13
Filing date: 2007-10-11
Publication date: 2008-05-22
Also published as: DE102006053693A1

Abstract

Two-phase mouthwash compositions which comprise, in a first phase (A), besides hydrogen peroxide, a sugar alcohol and a nonionic surfactant, and in a second phase (B), that is spatially separate from phase (A), an aqueous or aqueous-alcoholic solution, have no undesired discolorations of the hydrogen peroxide phase after opening the packaging and/or during storage and are suitable for the basic cleaning of the oral cavity and bleaching of the teeth.

Description

"Two-phase mouthwash"

The invention relates to ready-to-use two-phase mouthwash compositions, a method for cleaning the oral cavity and the use of a sugar alcohol and a nonionic surfactant in the hydrogen peroxide phase of the mouthwash to reduce and / or inhibit discoloration of the hydrogen peroxide phase.

In the oral and dental care in addition to toothpastes often liquid preparations are used, in which the cleaning and care effect is achieved by the contact of the preparation with the oral cavity, without the need for an additional tool, such as a toothbrush. These preparations, which are commonly referred to as mouthwashes, thereby offering a special ease of use and also ensure that even difficult to reach areas of the oral cavity, especially on the teeth, come into contact with the preparation.

While mouthwashes were used in the past merely to refresh the mouth and throat and to improve the bad breath, they take over today tasks such. A plaque-dissolving effect, and they serve as carriers of anti-caries agents or antibacterial agents for plaque control. Mouthwashes are offered as low-viscosity aqueous or aqueous-alcoholic formulations or as water-dilutable concentrates. The application in the form of a low-viscosity preparation is a good distribution availability and good contact with the oral cavity achieved. In addition to the cleaning of the teeth, the consumer of the generic products also expected a care of the teeth and the oral cavity. In particular, a "clean" feel, ie a smooth and shiny tooth surface as well as a fresh mouthfeel are essential aspects for the buying incentive of oral and dental care and cleaning preparations. A successful remedy of the generic type should therefore thoroughly clean the teeth without damaging the tooth or tooth surface while reducing and / or preventing bad breath.

The use of peroxides as a component of oral and dental care has long been known, firstly because peroxy compounds have an antimicrobial effect against many harmful bacteria of the oral cavity and in this way for the treatment of gingivitis Periodontitis and contribute to the fight against dental plaque. On the other hand, peroxides, because of their bleaching and oxidizing effect, lighten dark-discolored teeth and thus contribute significantly to the cleaning success of toothpastes and mouthwashes.

A disadvantage of peroxide-containing preparations is the lack of stability of peroxides in aqueous solution, which can lead to a loss of active peroxide oxygen in the course of prolonged storage, especially at higher ambient temperatures. This problem is particularly serious when the preparation contains oxidizable organic components or components which cause a neutral or weakly basic pH or otherwise cause activation of the peroxide oxygen.

It has therefore long been desirable to produce a mouthwash based on peroxides that is storage stable and meets the above requirements.

EP 2 897 714 A1 describes a two-phase mouthwash which comprises hydrogen peroxide and an acid in a first, clear phase and an aqueous or aqueous-alcoholic solution based on typical mouthwash constituents in the second phase.

However, during the manufacture and storage of such mouthwashes, the problem in the past has been that the clear hydrogen peroxide phase has discolored, which is undesirable for application and aesthetic reasons.

The aim of the present invention was thus to produce a peroxide-containing mouthwash, in which the clear phase of hydrogen peroxide does not discolour after use of the mouthwash and during storage.

In particular, discolorations due to metal ions in an oxidative medium should be reduced or inhibited. Such discolorations can occur, for example, when the mouthwash is diluted in use with tap water and traces of tap water and thus traces of metal ions that originate from the water pipes, get into the mouthwash.

Another possibility is that metal ions are trafficked in the mouthwash during the production of mouthwashes and lead there later during storage to the unwanted discoloration.

This object has been met to a great extent by the provision of a two-phase mouthwash which contains in the hydrogen peroxide phase a sugar alcohol and a special nonionic surfactant. The present invention accordingly provides two-phase ready-to-use mouthwash compositions consisting of two separately packaged components which are combined in a sales unit and mixed together before use, and the first component (A) comprises, in addition to an aqueous hydrogen peroxide solution, at least one sugar alcohol and at least one or more a plurality of nonionic surfactant (s), preferably ethoxylated nonionic surfactant (s), and more preferably ethoxylated nonionic surfactant (s) having from 30 to 100, preferably 40 to 90, and most preferably 50 to 70 EO groups, and the second component (B) contain an aqueous or aqueous-alcoholic solution based on one or more substances from the group of surfactants, flavorings and oral hygiene agents.

For the purposes of the present invention, "mouthwash" or "mouthwash composition" are also so-called mouth rinses, anti-plaque rinses, etc. "Ready for use" in the context of the present invention means that the composition is removed from the packaging without further processing steps (eg dilution) and removed from the packaging Consumers can and should be used.

The mouthwashes of the invention meet the above requirements to a high degree. They allow a thorough cleaning of the oral cavity and the teeth and do not exhibit the problem of discoloration of the hydrogen peroxide phase. In particular, they inhibit the discoloration of the hydrogen peroxide phase, which is caused by metal ions, in particular by Cu ²⁺ ions.

As a further advantage, it was found that also a reduction of the H ₂ O ₂ content compared to the mouthwashes of EP 897 714 A1 led to a reduction of the discoloration without the desired cleaning and bleaching performance of the mouthwashes was thereby reduced.

The mouthwash composition according to the invention contains, based on its weight in component (A), 0.1 to 20% by weight, preferably 0.2 to 15% by weight, more preferably 0.5 to 10% by weight and in particular 1 to 5% by weight of arabitol, xylitol, galactitol, mannitol, sorbitol and / or mixtures thereof.

Particularly preferred according to the invention is the use of sorbitol as an additive in component (A).

As a further essential ingredient, the mouthwashes according to the invention, based on their weight in component (A), contain 0.01 to 5% by weight, preferably 0.02 to 3% by weight, especially preferably 0.05 to 2 wt .-% and in particular 0.08 to 1 wt .-% ethoxylated, hydrogenated

Castor oil.

According to the invention, it is particularly preferable, for example, to use the substance of the INCI

Designation PEG-60 Hydrogenated Castor OiI sold by the company Goldschmidt

Commercial product Tagat ^® CH 60.

As a third obligatory component, the mouthwash compositions of the invention contain hydrogen peroxide, which in the component (A), by weight, in an amount of 0.01 to 10 wt .-%, preferably from 0.02 to 5 wt .-% and in particular from 0.05 to 2 wt .-% is included.

The mouthwash compositions according to the invention contain, in addition to the ingredients mentioned, further constituents which originate, for example, from the group of further active ingredients and / or adjuvants. Another ingredient that is preferably included is water, which may be included in the compositions of the invention in amounts up to 99 wt .-%. Preferred compositions according to the invention contain from 30 to 99% by weight of water, more preferably from 40 to 98% by weight, particularly preferably from 50 to 95% by weight and in particular from 70 to 90% by weight of water, in each case based on the total composition, containing the components (A) and (B).

The following describes the ingredients which are in the mouthwash compositions according to the invention in phase (B).

The mouthwash compositions of the present invention may contain, in addition to the foregoing essential ingredients and water, other ingredients of oral cleansers, mouthwashes, dentifrices and / or dentifrices. The preferred further ingredients are described below.

A preferred class of ingredients which may be included in the mouthwash compositions of the present invention are the surfactants.

The term "surfactants" is understood as meaning surface-active substances which form adsorption layers on the upper and boundary surfaces or which can aggregate in volume phases to give micelle colloids or lyotropic mesophases. A distinction is made between anionic surfactants consisting of a hydrophobic radical and a negatively charged hydrophilic head group, amphoteric surfactants which carry both a negative and a compensating positive charge, cationic surfactants which, in addition to a hydrophobic radical, have a positively charged hydrophilic group, and nonionic surfactants which have no charges but strong dipole moments and are highly hydrated in aqueous solution. Suitable anionic surfactants (E1) in preparations according to the invention are all anionic surfactants suitable for use on the human body. These are characterized by a water-solubilizing, anionic group such as. As a carboxylate, sulfate, sulfonate or phosphate group and a lipophilic alkyl group having about 8 to 30 carbon atoms. In addition, glycol or polyglycol ether groups, ester, ether and amide groups and hydroxyl groups may be present in the molecule. Examples of suitable anionic surfactants are, in each case in the form of the sodium, potassium and ammonium as well as the mono-, di- and trialkanolammonium salts having 2 to 4 C atoms in the alkanol group, linear and branched fatty acids having 8 to 30 C atoms (Soap),

Ethercarbonsäuren the formula R-CKCh ^ -Ch ^ O ^ -Ch ^ -COOl-l, in the R is a linear

Alkyl group having 8 to 30 C atoms and x = 0 or 1 to 16,

Acylsarcosides having 8 to 24 carbon atoms in the acyl group,

Acyltaurides having 8 to 24 carbon atoms in the acyl group,

Acyl isethionates having 8 to 24 carbon atoms in the acyl group,

Sulfobernsteinsäuremono- and -dialkylester having 8 to 24 carbon atoms in the alkyl group and

Sulfosuccinic acid mono-alkylpolyoxyethylester having 8 to 24 carbon atoms in the alkyl group and

1 to 6 oxyethyl groups, linear alkanesulfonates having 8 to 24 carbon atoms, linear alpha-olefin sulfonates having 8 to 24 carbon atoms,

Alpha sulfo fatty acid methyl esters of fatty acids having 8 to 30 carbon atoms, - alkyl sulfates and alkyl polyglycol ether sulfates of the formula RO (CH ₂ -CH ₂ O) _x -OSO ₃ H, in which R is a preferably linear alkyl group having 8 to 30 carbon atoms and x = 0 or 1 to 12, sulfated hydroxyalkylpolyethylene and / or hydroxyalkylene-propylene glycol ethers

Sulfonates of unsaturated fatty acids having 8 to 24 carbon atoms and 1 to 6 double bonds

Esters of tartaric acid and citric acid with alcohols, the addition products of about 2-15

Represent molecules of ethylene oxide and / or propylene oxide with fatty alcohols having 8 to 22 carbon atoms,

Alkyl and / or alkenyl ether phosphates of the formula (E1-I),

R ¹ (OCH ₂ CH ₂ ) _n -OP (O) (OX) -OR ² (EM)

in the R ^{1 is} preferably an aliphatic hydrocarbon radical having 8 to 30 carbon atoms, R ^{2 is} hydrogen, a radical (CH ₂ CH ₂ O) _n R ² or X, n is from 1 to 10 and X is hydrogen, an alkali metal radical or alkaline earth metal or NR ³ R ⁴ R ⁵ R ⁶ , where R ³ to R ⁶ independently of one another represent hydrogen or a C ₁ to C ₄ hydrocarbon radical, sulfated fatty acid alkylene glycol esters of the formula (E1-II)

R ⁷ CO (AIkO) _n SO ₃ M (EI-II) in the R ⁷ CO- for a linear or branched, aliphatic, saturated and / or unsaturated acyl radical having 6 to 22 C atoms, Alk for CH ₂ CH ₂ , CHCH ₃ CH ₂ and / or

CH ₂ CHCH ₃ , n is from 0.5 to 5 and M is a cation,

Monoglyceride sulfates and monoglyceride ether sulfates of the formula (E1-III)

CH ₂ O (CH ₂ CH ₂ O) _x -COR ⁸

I CHO (CH ₂ CH ₂ O) _y H (E1-III)

I

CH ₂ O (CH ₂ CH ₂ O) _Z SO ₃ X

in which R ⁸ CO is a linear or branched acyl radical having 6 to 22 carbon atoms, x, y and z are in total O or numbers from 1 to 30, preferably 2 to 10, and X is an alkali or alkaline earth metal. Typical examples of monoglyceride (ether) sulfates suitable for the purposes of the invention are the reaction products of lauric acid monoglyceride, coconut fatty acid monoglyceride, palmitic acid monoglyceride, stearic acid monoglyceride, oleic acid monoglyceride and tallow fatty acid monoglyceride and their ethylene oxide adducts with sulfur trioxide or chlorosulfonic acid in the form of their sodium salts. Preferably, monoglyceride sulfates of the formula (E1-III) are used in which R ⁸ CO is a linear acyl radical having 8 to 18 carbon atoms, amide-ether carboxylic acids,

Condensation products of C ₈ - C ₃₀ - fatty alcohols with protein hydrolysates and / or amino acids and their derivatives, which are known to the skilled person as protein fatty acid condensates, such as Lamepon ^® - types Gluadin ^® - types Hostapon ^® KCG or Amisoft ^® - types.

Preferred anionic surfactants are alkyl sulfates, alkyl polyglycol ether sulfates and ether carboxylic acids having 10 to 18 C atoms in the alkyl group and up to 12 glycol ether groups in the molecule, sulfosuccinic acid mono- and dialkyl esters having 8 to 18 C atoms in the alkyl group and sulfosuccinic acid monoalkylpolyoxyethylester with 8 to 18 carbon atoms in the alkyl group and 1 to 6 oxyethyl groups, Monoglycerdisulfate, alkyl and Alkenyletherphosphate and Eiweissfettsäurekondensate.

Zwitterionic surfactants (E2) are those surface-active compounds which carry in the molecule at least one quaternary ammonium group and at least one -COO ⁽⁾ or -SO ₃ ⁽⁾ group. Particularly suitable zwitterionic surfactants are the so-called betaines such as the N-alkyl-N, N-dimethylammonium glycinates, for example the cocoalkyl dimethylammo- niumglycinat, N-acyl-aminopropyl-N, N-dimethylammoniumglycinate, for example, the cocoacylaminopropyl-dimethylammoniumglycinat, and 2-alkyl-3-carboxymethyl-3-hydroxyethyl imidazoline having in each case 8 to 18 carbon atoms in the alkyl or acyl group and cocoacylaminoethylhydroxyethylcarboxymethylglycinate. A preferred zwitterionic surfactant is the fatty acid amide derivative known by the INCI name Cocamidopropyl Betaine.

Ampholytic surfactants (E3) are understood as meaning those surface-active compounds which contain, in addition to a C ₈ -C ₂₄ -alkyl or -acyl group, at least one free amino group and at least one -COOH or -SO ₃ H group in the molecule and for forming internal Salts are capable. Examples of suitable ampholytic surfactants are N-alkylglycines, N-alkylpropionic acids, N-alkylaminobutyric acids, N-alkyliminodipropionic acids, N-hydroxyethyl-N-alkylamidoproylglycines, N-alkyltaurines, N-alkylsarcosines, 2-alkylaminopropionic acids and alkylaminoacetic acids with each about 8 to 24 carbon atoms in the alkyl group. Particularly preferred ampholytic surfactants are N-cocoalkylaminopropionate, cocoacylaminoethylaminopropionate and C ₁₂ -C ₁₈ acylsarcosine.

Nonionic surfactants (E4) contain as hydrophilic group e.g. a polyol group, a polyalkylene glycol ether group, or a combination of polyol and polyglycol ether groups. Such compounds are, for example

Addition products of 2 to 50 moles of ethylene oxide and / or 0 to 5 moles of propylene oxide to linear and branched fatty alcohols having 8 to 30 carbon atoms, to fatty acids having 8 to 30 carbon atoms

Atoms and alkylphenols having 8 to 15 carbon atoms in the alkyl group, with a methyl or C ₂ - C ₆ - alkyl radical end-capped addition products of 2 to 50 moles of ethylene oxide and / or 0 to 5 moles of propylene oxide to linear and branched

Fatty alcohols having 8 to 30 carbon atoms, to fatty acids having 8 to 30 carbon atoms and alkylphenols having 8 to 15 carbon atoms in the alkyl group, such as those among the

Sales names Dehydrol® ^® LS, Dehydrol® ^® LT (Cognis) types,

C ₁₂ -C ₃₀ -fatty acid mono- and diesters of addition products of 1 to 30 moles of ethylene oxide with glycerol,

Addition products of 5 to 60 moles of ethylene oxide with castor oil and hydrogenated castor oil,

Polyol fatty acid esters, such as the commercial product Hydagen ^® HSP (Cognis) or

Sovermol types (Cognis), alkoxylated triglycerides, alkoxylated fatty acid alkyl esters of the formula (E4-I)

R ¹ CO- (OCH ₂ CHR ² ) _W OR ³ (E4-I) in the R ¹ CO for a linear or branched, saturated and / or unsaturated acyl radical having 6 to 22 carbon atoms, R ^{2 is} hydrogen or methyl, R ^{3 is} linear or branched

Alkyl radicals having 1 to 4 carbon atoms and w is from 1 to 20,

Amine oxides,

hydroxy mixed,

Sorbitan fatty acid esters and adducts of ethylene oxide with sorbitan fatty acid esters such as the polysorbates,

Sugar fatty acid esters and addition products of ethylene oxide with sugar fatty acid esters,

Addition products of ethylene oxide to fatty acid alkanolamides and fatty amines,

Sugar surfactants of the alkyl and alkenyl oligoglycoside type of formula (E4-II),

in which R ^{4 is} an alkyl or alkenyl radical having 4 to 22 carbon atoms, G is a sugar radical having 5 or 6 carbon atoms and p is a number from 1 to 10. They can be obtained by the relevant methods of preparative organic chemistry. The alkyl and alkenyl oligoglycosides can be derived from aldoses or ketoses with 5 or 6 carbon atoms, preferably glucose. The preferred alkyl and / or alkenyl oligoglycosides are thus alkyl and / or alkenyl oligoglucosides. The index number p in the general formula (E4-II) indicates the degree of oligomerization (DP), ie the distribution of mono- and oligoglycosides and stands for a number between 1 and 10. While p in the individual molecule must always be integer and here before For all given values p = 1 to 6, the value p for a given alkyloligoglycoside is an analytically determined arithmetic quantity, which usually represents a fractional number. Preference is given to using alkyl and / or alkenyl oligoglycosides having an average degree of oligomerization p of from 1.1 to 3.0. From an application point of view, those alkyl and / or alkenyl oligoglycosides whose degree of oligomerization is less than 1.7 and in particular between 1.2 and 1.4 are preferred. The alkyl or alkenyl radical R ⁴ can be derived from primary alcohols having 4 to 11, preferably 8 to 10 carbon atoms. Typical examples are butanol, caproic alcohol, caprylic alcohol, capric alcohol and undecyl alcohol and technical mixtures thereof, as obtained, for example, in the hydrogenation of technical fatty acid methyl esters or in the hydrogenation of aldehydes from Roelen's oxo synthesis. Alkyl oligoglucosides of chain length of C ₈ -C ₀ (DP = 1 to 3), which are obtained as first runnings in the separation of technical C ₈ -C ₈ coconut oil fatty alcohol and having a content of less than 6 wt .-% of ₂ - Alcohol can be contaminated and alkyl oligoglucosides based on technical Cg _/ n-oxo alcohols (DP = 1 to 3). The alkyl or alkenyl radical R ¹⁵ can also be derived from primary alcohols having 12 to 22, preferably 12 to 14 carbon atoms. Typical examples are lauryl alcohol, myristyl alcohol, Cetyl alcohol, palmoleyl alcohol, stearyl alcohol, isostearyl alcohol, oleyl alcohol, elaidyl alcohol, petroselinyl alcohol, arachyl alcohol, gadoleyl alcohol, behenyl alcohol, erucyl alcohol, brassidyl alcohol, and technical mixtures thereof which can be obtained as described above. Alkyl oligoglucosides based on hydrogenated _{C12 /} i ₄ coconut alcohol with a DP of 1 to 3

Sugar surfactants of the fatty acid N-alkyl polyhydroxyalkylamide type, a nonionic surfactant of the formula (E4-III),

R ⁵ CO-NR ⁶ - [Z] (E4-III)

R ^{5 is} CO for an aliphatic acyl radical having 6 to 22 carbon atoms, R ^{6 is} hydrogen, an alkyl or hydroxyalkyl radical having 1 to 4 carbon atoms and [Z] is a linear or branched polyhydroxyalkyl radical having 3 to 12 carbon atoms and 3 to 10 hydroxyl groups stands. The fatty acid N-alkyl polyhydroxyalkylamides are known substances which are usually obtained by reductive amination of a reducing sugar with ammonia, an alkylamine or an alkanolamine and subsequent acylation with a fatty acid, a fatty acid alkyl ester or a fatty acid chloride. Preferably, the fatty acid N-alkylpolyhydroxyalkylamides are derived from reducing sugars having 5 or 6 carbon atoms, especially glucose. The preferred fatty acid N-alkylpolyhydroxyalkylamides are therefore fatty acid N-alkylglucamides as represented by the formula (E4-IV):

R ⁷ CO-NR ⁸ -CH ₂ - (CHOH) ₄ -CH ₂ OH (E4-IV)

The fatty acid N-alkylpolyhydroxyalkylamides used are preferably glucamides of the formula (E4-IV) in which R ^{8 is} hydrogen or an alkyl group and R ⁷ CO is the acyl radical of caproic acid, caprylic acid, capric acid, lauric acid, myristic acid, palmitic acid, palmitic acid, Stearic acid, isostearic acid, oleic acid, elaidic acid, petroselinic acid, linoleic acid, linolenic acid, arachidic acid, gadoleic acid, behenic acid or erucic acid or those technical mixtures. Particular preference is given to fatty acid N-alkylglucamides of the formula (E4-IV) which are obtained by reductive amination of glucose with methylamine and subsequent acylation with lauric acid or C 12/14 coconut fatty acid or a corresponding derivative. Furthermore, the polyhydroxyalkylamides can also be derived from maltose and palatinose.

The preferred nonionic surfactants are the alkylene oxide addition products of saturated linear fatty alcohols and fatty acids having in each case 2 to 30 moles of ethylene oxide per mole of fatty alcohol or fatty acid. Preparations with excellent properties are also obtained if they contain fatty acid esters of ethoxylated glycerol as nonionic surfactants.

These connections are identified by the following parameters. The alkyl radical R contains 6 to 22 carbon atoms and may be both linear and branched. Preference is given to primary linear and methyl-branched in the 2-position aliphatic radicals. Such alkyl radicals are, for example, 1-octyl, 1-decyl, 1-lauryl, 1-myristyl, 1-cetyl and 1-stearyl. Particularly preferred are 1-octyl, 1-decyl, 1-lauryl, 1-myristyl. When using so-called "oxo-alcohols" as starting materials, compounds with an odd number of carbon atoms in the alkyl chain predominate.

Furthermore, very particularly preferred nonionic surfactants are the sugar surfactants. These may preferably be present in the agents used according to the invention in amounts of from 0.1 to 20% by weight, based on the total agent. Amounts of 0.5-15% by weight are preferred, and most preferred are amounts of 0.5-7.5% by weight.

The compounds used as surfactant with alkyl groups may each be uniform substances. However, it is usually preferred to start from the production of these substances from native plant or animal raw materials, so as to obtain substance mixtures with different, depending on the particular raw material alkyl chain lengths.

In the case of the surfactants which are adducts of ethylene oxide and / or propylene oxide with fatty alcohols or derivatives of these addition products, both products with a "normal" homolog distribution and those with a narrow homolog distribution can be used. By "normal" homolog distribution are meant mixtures of homologs obtained in the reaction of fatty alcohol and alkylene oxide using alkali metals, alkali metal hydroxides or alkali metal alcoholates as catalysts. Narrowed homolog distributions are obtained when, for example, hydrotalcites, alkaline earth metal salts of ether carboxylic acids, alkaline earth metal oxides, hydroxides or alkoxides are used as catalysts. The use of products with narrow homolog distribution may be preferred.

Cationic surfactants of the quaternary ammonium compound type, the esterquats and the amidoamines can be used according to the invention. Preferred quaternary ammonium compounds are ammonium halides, in particular chlorides and bromides, such as alkyltrimethylammonium chlorides, dialkyldimethylammonium chlorides and trialkylmethylammonium chlorides, eg. Cetyltrimethylammonium chloride, stearyltrimethylammonium chloride, distearyldimethylammonium chloride, lauryldimethylammonium chloride, lauryldimethylbenzylammonium chloride and tricetylmethylammonium chloride, as well as the imidazolium compounds known under the INCI names Quaternium-27 and Quaternium-83. The long alkyl chains of the above-mentioned surfactants preferably have 10 to 18 carbon atoms.

According to the invention, preference is given to using QAV with behenyl radicals, in particular those known as behentrimonium chloride or bromide (docosanyltrimethylammonium chloride or bromide). Other preferred QAV's have at least two behenyl residues, with QAV being particularly preferred, which are two behenyl residues on an imidazolinium backbone. Commercially available, these substances, for example, under the names Genamin ^® KDMP (Clariant) and Crodazosoft ^® DBQ (Crodauza) are.

Esterquats are known substances which contain both at least one ester function and at least one quaternary ammonium group as a structural element. Preferred esterquats are quaternized ester salts of fatty acids with triethanolamine, quaternized ester salts of fatty acids with diethanolalkylamines and quaternized ester salts of fatty acids with 1,2-dihydroxypropyldialkylamines. Such products are marketed under the trade names Stepantex® ^®, ^® and Dehyquart® Armocare® ^®. The products Armocare ^® VGH-70, a N, N-bis (2-palmitoyloxyethyl) dimethylammonium chloride, as well as Dehyquart ^® F-75, Dehyquart ^® C-4046, Dehyquart ^® L80 and Dehyquart ^® AU-35 are examples of such esterquats.

The alkylamidoamines are usually prepared by amidation of natural or synthetic fatty acids and fatty acid cuts with dialkylaminoamines. An inventively particularly suitable compound from this group of substances under the name Tegoamid ^® S 18 commercial stearamidopropyl dimethylamine is.

The surfactant (s) are preferably used in the mouthwash compositions according to the invention in amounts of from 0.01 to 10% by weight, smaller amounts, for example from 0.05 to 5% by weight or from 0.1 to 2, 5 wt .-%, each based on the total agent, are preferred. With particular preference, in addition to the nonionic surfactants necessarily contained in component (A), further nonionic surfactants are used, wherein in phase (B) the ethoxylated nonionic surfactants and the sugar surfactants are again particularly preferred among them. Preferred mouthwash compositions according to the invention contain in the phase (B) sugar surfactants of the alkyl and alkenyl oligoglycoside type of the formula R ⁴ O- [GJ _p1 in the R ⁴ for an alkyl or alkenyl radical having 4 to 22 carbon atoms, G for a sugar radical with 5 or 6 carbon atoms and p stands for numbers from 1 to 10, whereby preferred sugar surfactants originate from the group of the alkyl polyglucosides which have a degree of oligomerization p of from 1 to 3, preferably from 1, 1 to 2 and in particular from 1, 2 to 1, 5 and as the alkyl radical R ^{4 is} a radical having 8 to 14 carbon atoms, preferably with 10 to 12 carbon atoms carry. Further preferred mouthwash compositions according to the invention are characterized in that in phase (B) they additionally contain 0.05 to 5% by weight, preferably 0.1 to 2.5% by weight and in particular 0.15 to 1.2% by weight. % nonionic surfactant (s), preferably ethoxylated nonionic surfactant (s), and in particular ethoxylated nonionic surfactant (s) having from 30 to 100, preferably 40 to 90, and especially 50 up to 70 EO groups included.

The mouthwash compositions of the invention may, for. B. also contain antimicrobial substances as preservatives or as antiplaque agents. Such substances may, for. B. be selected from p-Hydroxybenzoesäuremethyl-, ethyl or propyl ester, sodium sorbate, sodium benzoate, bromochlorophene, triclosan, phenyl salicylates, biguanides z. Chlorhexidine, thymol, etc. According to the invention preferred mouthwash compositions are characterized in that they additionally antiplaque agents, preferably p-hydroxybenzoic acid methyl, ethyl or propyl, sodium sorbate, sodium benzoate, bromochlorophene, triclosan, phenyl salicylic, biguanides z. B. chlorhexidine, thymol, preferably in amounts of 0.01 to 5 wt.%, Preferably from 0.02 to 2.5 wt.% And in particular from 0.03 to 1, 5 wt.%, Each based on the total Means, included.

Particularly preferred according to the invention is the use of biguanidine compounds. These antimicrobially effective biguanide compounds are preferably contained in a very low concentration of 0.0025 to 0.04% by weight. As antimicrobial effective Biguanidverbindung is preferably 1, 1 in-hexamethylene-bis (4-chlorophenyl) - biguanide ("chlorhexidine") in the form of a water-soluble, physiologically acceptable salt, eg. B. used in the form of acetate or as gluconate. Other antimicrobial biguanide compounds which are suitable according to the invention are e.g. B. the polyhexamethylene biguanide compounds of the type Vantocil ^(R) IB (ICI) or the 1, 6-bis (4-chlorobenzylbiguanido) hexane (fluorohexidine).

According to preferred mouthwash compositions according to the invention are characterized in that they additionally antiplaque agents, preferably p-hydroxybenzoic acid methyl, ethyl or propyl esters, sodium sorbate, sodium benzoate, bromochlorophene, triclosan, phenyl salicylic, biguanides z. As chlorhexidine, thymol, preferably in amounts of 0.01 to 2.5 wt.%, Preferably from 0.05 to 1 wt.% And in particular from 0.1 to 0.5 wt.%, Each based on the total Means, included.

Another preferred group of ingredients that may be included in the compositions of the invention are the anti-caries agents. These may be selected, for example, from organic or inorganic fluorides, for. Example of sodium fluoride, potassium fluoride, sodium monofluorophosphate and sodium fluorosilicate. Also zinc fluoride, tin (II) fluoride are prefers. An amount of 0.01-0.2% by weight of fluorine should preferably be present in the form of the compounds mentioned.

The mouthwash composition according to the invention additionally contains anti-caries agents, preferably fluorine compound (s), in particular sodium fluoride, potassium fluoride, sodium monofluorophosphate, zinc fluoride, tin fluoride and sodium fluorosilicate, preferably in amounts of from 0.01 to 2.5% by weight, preferably from 0.02 to 1% by weight .% And in particular from 0.03 to 0.5 wt.%, Each based on the total agent, are inventively preferred.

The oral and dental care and cleaning agents, in particular the toothpastes, for example, may also contain substances that are effective against tartar. Such substances may be, for example, chelating agents such. As ethylenediaminetetraacetic acid and its sodium salts, pyrophosphate salts such as the water-soluble dialkali or Tetraalkalimetallpyrophosphat- salts, z. B. Na ₄ P ₂ O ₇ , K ₄ P ₂ O ₇ , Na ₂ K ₂ P ₂ O ₇ , Na ₂ H ₂ P ₂ O ₇ and K ₂ H ₂ P ₂ O ₇ or polyphosphate salts, the z. B. from water-soluble Alkalimethalltripolyphosphaten as sodium tripolyphosphate and potassium tripolyphosphate can be selected.

According to preferred mouthwash compositions are characterized in that they additionally phosphate (s), preferably alkali metal phosphate (s) and in particular sodium tripolyphosphate, preferably in amounts of 0.1 to 5 wt .-%, particularly preferably from 0.2 to 2.5 wt. -% and in particular from 0.3 to 1 wt .-%, each based on the total agent included.

The mouthwash composition according to the invention further contains, based on its weight, from 0.1 to 40% by weight of ethanol, the statement referring to pure alcohol (100%), even if this was not used as 100% ethanol, since ethanol is mixed with water Azeotrope, which consists of 95.57 wt .-% ethanol and 4.43 wt .-% water and boiling constant at 78.2 ° C. With particular preference, the mouthwash compositions according to the invention contain 0.5 to 30 wt .-%, preferably 1 to 25 wt .-% and in particular 5 to 20 wt .-% ethanol.

The mouthwash compositions of the invention may also contain glycerol. Glycerol is referred to IUPAC as 1, 2,3-propanetriol, the INCI name is: glycerol, other names are, for example, 1, 2,3-trihydroxypropane, glycerol, oil sweet, or E 422. According to the invention preferred mouthwash compositions contain by weight 1 to 15 wt .-% glycerol, wherein mouthwash compositions according to the invention are preferred which contain 2 to 12 wt .-%, preferably 2.5 to 11 wt .-% and in particular 3 to 10 wt .-% glycerol based on their weight. In addition to glycerin, the mouthwash compositions of the invention may contain further polyhydroxy compounds, preferably alcohols having at least 2 OH groups, more preferably mannitol, polyethylene glycol, polypropylene glycol and mixtures thereof.

Among the polyhydroxy compounds, those having 2 to 12 OH groups and especially those having 2, 3, 4, 5, 6 or 10 OH groups are preferred.

Polyhydroxy compounds having 2 OH groups are, for example, glycol (CH ₂ (OH) CH ₂ OH) and other 1, 2-diols such as H- (CH ₂ ) _n -CH (OH) CH ₂ OH where n = 2, 3, 4 , 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20. Also 1,3-diols such as H- (CH ₂ ) _n -CH ( OH) CH ₂ CH ₂ OH with n = 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20 used according to the invention. The (n, n + 1) or (n, n + 2) diols with non-terminal OH groups can also be used.

Important representatives of polyhydroxy compounds having 2 OH groups are also the polyethylene and polypropylene glycols.

Particular preference is given to mouthwash compositions according to the invention which contain the polyhydroxy compounds preferably in amounts of from 1 to 20% by weight, more preferably from 2 to 15% by weight and in particular from 3 to 10% by weight, based in each case on the total composition ,

The mouthwash compositions may also contain the insensitivity of the teeth-enhancing substances, for example, potassium salts such. As potassium nitrate, potassium citrate, potassium chloride, potassium bicarbonate and potassium oxalate. According to the invention preferred mouthwash compositions are characterized in that they the insensitivity of the teeth-enhancing substances, preferably potassium salts, more preferably potassium nitrate and / or potassium citrate and / or potassium chloride and / or potassium bicarbonate and / or potassium oxalate, preferably in amounts of 0.05 to 5 wt. %, particularly preferably from 0.1 to 2.5% by weight, more preferably from 0.2 to 1% by weight and in particular from 0.25 to 0.75% by weight, in each case based on the total agent ,

The compositions according to the invention can also additionally other wound-healing and anti-inflammatory substances, eg. B. agents for gingivitis included. Such substances may, for. B. be selected from allantoin, azulen, chamomile extracts, tocopherol, panthenol, bisabolol, sage extracts.

Suitable non-cationic, bactericidal components are, for example, phenols, resorcinols, bisphenols, salicylanilides and their halogenated derivatives, halogenated carbanilides and p-hydroxybenzoic acid esters. Particularly preferred antimicrobial components are halogenated Diphenyl ether, for example 2,4-dichloro-2'-hydroxydiphenyl ether, 4,4'-dichloro-2'-hydroxydiphenyl ether, 2,4,4'-tribromo-2'-hydroxydiphenyl ether and 2,4,4'-trichloro-2 'hydroxydiphenyl ether (Triclosan). They are preferably used in amounts of from 0.01 to 1% by weight in the mouthwash compositions according to the invention. Triclosan is particularly preferably used in an amount of 0.01-0.3% by weight.

D-panthenol D - (+) - 2,4-dihydroxy-N- (3-hydroxypropyl) -3,3-dimethyl-butyramide exhibits a biological activity corresponding to pantothenic acid. The pantothenic acid (R - (+) - N - (2,4-dihydroxy-3,3-dimethylbutyryl-β-alanine) is a precursor in the biosynthesis of coenzyme A and is counted to the vitamin B complex (B3). These substances are known to promote wound healing and have a beneficial effect on the skin, and have therefore been occasionally described in toothpastes The mouthwash compositions of the present invention preferably contain 0.05-5% by weight of panthenol or a salt of pantothenic acid ,

Retinol (3,7-dimethyl-9- (2,6,6-trimethyl-1-cyclohexenyl) -2,4,6,8-nonatetraen-1-ol is the international common name for vitamin A1, but may also be used instead of retinol one of its derivatives having similar biological activity, for example an ester or the retinoic acid (tretinoin), one of its salts or its esters is preferably used, preferably a retinol ester, in particular a fatty acid ester of a fatty acid having 12-22 carbon atoms Retinol palmitate is suitable When using a retinol ester, eg retinol palmitate with an activity of 1.710 ⁶ IU per g, an amount of 0.001 to 0.1% by weight is preferred If other retinol derivatives are used It is recommended to use at a concentration of 10 ³ to 10 ⁶ IU (international units) per 100 g.

Preferred mouthwash compositions according to the present invention preferably contain, in addition to the aforementioned mandatory ingredients

0.01 - 1 wt .-% of a halogenated diphenyl ether

0.05 - 5 wt .-% panthenol or a salt of pantothenic acid and

0.01-0.1% by weight of a retinol ester, preferably retinol palmitate.

Suitable water-insoluble aroma oils are all natural and synthetic flavors customary for oral and dental care products. Natural flavors can be used both in the form of the isolated from the drugs ethereal Ie as well as isolated from these individual components. At least one aromatic oil should be selected from the group of peppermint oil, spearmint oil, aniseed oil, star aniseed oil, caraway oil, eucalyptus oil, fennel oil, cinnamon oil, clove oil, geranium oil, sage oil, pimento oil, thyme oil, marjoram oil, basil oil, citrus oil, Gaultheria oil or one or more components isolated or synthetically produced therefrom this Ie be contained. The most important components of the mentioned Ie are z. Menthol, carvone, anethole, cineole, eugenol, Cinnamaldehyde, caryophyllene, geraniol, citronellol, linalool, salves, thymol, terpinene, terpinol, methylchavicol and methyl salicylate. Other suitable flavors are z. For example, menthyl acetate, vanillin, ionone, linalyl acetate, rhodinol and piperitone.

Solubilizers from the group of ethoxylated Fettsäureglyceride include especially adducts of 20-60 moles of ethylene oxide with mono- and diglycerides of linear fatty acids having 12-18 carbon atoms or triglycerides of hydroxy fatty acids such as oxystearic acid or ricinoleic acid. Further suitable solubilizers are ethoxylated fatty acid sorbitan partial esters; these are preferably addition products of 20-60 moles of ethylene oxide with sorbitan monoesters and sorbitan diesters of fatty acids with 12-18 carbon atoms. Also suitable solubilizers are fatty acid partial esters of glycerol or sorbitan ethoxylates; these are preferably mono- and diesters of C 12-18 fatty acids and adducts of 20-60 moles of ethylene oxide with 1 mole of glycerol or 1 mole of sorbitol.

The preparations according to the invention preferably contain, as solubilizers, adducts of 20-60 mol of ethylene oxide with hydrogenated or uncured castor oil (i.e., with oxystearic acid or ricinoleic acid triglyceride), with glycerol mono- and / or distearate or with sorbitan mono- and / or distearate.

In addition to the compulsory components mentioned, the preparations according to the invention may contain further components which are known per se and which are customary in antimicrobial preparations for the field of personal hygiene in order to improve their appearance, taste or handling. To improve the appearance z. As physiologically acceptable dyes, opacifiers or pearlescing agents are added. To improve the taste, natural or synthetic sweeteners, preferably cariogenic carbohydrate-free sweeteners may be added. These include, for example, saccharin sodium, cyclamates, acesulfame potassium, aspartame ^(R) (L-aspartyl-L-phenylalanine methyl ester). Further suitable sweeteners are, for example, sucrose, lactose, meltose, fructose.

The mouthwash composition of the invention preferably have viscosities (gemesen at 20 ⁰ C with Brookfield viscosimeter DV IN, spindle 4, 4 U / min) below 1000 mPas. Particular preference is given to viscosities below 500 mPas, more preferably below 250 mPas and in particular below 100 mPas.

If, in individual cases, higher viscosities are desired, the mouthwash compositions according to the invention can be used as consistency regulators, for. As natural and / or synthetic water-soluble polymers such as alginates, carrageenan, tragacanth, starch and starch ethers, cellulose ethers such. Carboxymethylcellulose (Na-SaIz), hydroxyethylcellulose, methylhydroxypropylcellulose, guar, acacia, agar-agar, xanthan-gum, succinoglycan-gum, Locust bean meal, pectins, water-soluble carboxyvinyl polymers (for example CarbopoKD types), polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycols, in particular those having molecular weights of 1 500-1 000 000.

Other substances that are suitable for viscosity control, z. B. phyllosilicates such. As montmorillonite clays, colloidal thickened silicas such. As airgel silicas, fumed silicas or finely ground precipitated silicas. It is also possible to use viscosity-stabilizing additives from the group of cationic, zwitterionic or ampholytic nitrogenous surfactants, hydroxypropyl-substituted hydrocolloids or polyethylene glycol / polypropylene glycol copolymers having an average molecular weight of from 1000 to 5000 or a combination of the compounds mentioned.

Another object of the present invention is a method for cleaning the oral cavity, in which a ready-to-use mouthwash composition according to the invention is introduced undiluted into the oral cavity and removed from it again after a contact time.

In preferred processes according to the invention, the reaction time is 10 seconds to 5 minutes, preferably 20 to 240 seconds, more preferably 30 to 180 seconds and especially 60 to 120 seconds. In further preferred inventive method, the ready solution is moved within the contact time in the mouth, which can assist the user by rinsing or Gurgelbewegungen.

Preferably, the introduction of the mouthwash composition according to the invention in the oral cavity in amounts of 10 to 200 ml, preferably from 50 to 150 ml, more preferably from 60 to 120 ml and in particular from 70 to 100 ml per application.

Particularly preferably, the use of the method according to the invention by the consumer can be ensured if the mouthwash compositions according to the invention are provided with a corresponding instruction for use. Such

Mouthwash compositions are essentially a "kit" of the packaged mouthwash composition and instructions for use.

Such kits of the invention comprise at least one package. This packaging is used in the not even dimensionally stable mouthwash compositions according to the invention for their storage and facilitates their dosage and use. Packaging preferred according to the invention are, for example, tubes, dispensers, bottles, cans, pots, pots, spray cans, boxes, buckets, boxes, tubs, etc. They can be made of a wide variety of materials, for example plastic, metal, glass, composites, etc. Packaging for cosmetic products in general and for specifically mouthwashes are wide in the art and, depending on the cosmetic product to be packaged, there is a wide variety of commercial packaging in a wide variety of shapes and sizes.

The packaged mouthwash compositions according to the invention can be provided in a kit with an outer packaging - but for cost reasons, this will only be practiced in higher-valued and higher-priced agents of the invention.

The outer packaging, like the packaging, can be made from a wide variety of materials and can take on a wide variety of shapes. For higher quality products, a tinplate can with removable lid can recommend. Also plastic boxes are possible embodiments. These outer packaging have the advantage of being appropriately decorated and used as a storage container after consumption. For products whose outer packaging is to be disposed of after use, a cardboard box is recommended. Cardboards have the advantage of low cost and easy printability. Colored and formal designs can be varied widely in these outer packaging.

Kits according to the invention which have at least one packaging directly surrounding the mouthwash composition and an outer packaging containing this packaging, which is preferably selected from cardboard boxes, are preferred according to the invention.

As a further component, the above kit according to the invention comprises an instruction manual which gives the consumer instructions for use of the mouthwash composition. "Instructions for use" in the sense of the present application can not only be written versions in any language, but also visual representations such as pictograms.

The instructions for use may be permanently attached to or attached to the packaging. Thus, in one embodiment of the present invention, the instructions for use may be applied to the outside of the package. The instructions for use may also be applied to the inside of the package in preferred embodiments of the present invention. This embodiment is particularly recommended in kits according to the invention, which have an outer packaging.

In the simplest case, the instructions for use may be printed directly on the outside and / or inside of the packaging, but it is also possible and preferred, separately prefabricated instructions for use, which may be designed fragrant, adherent to the packaging to connect., These include, among other things, in the pasting of labels, shrinking of films, the mechanical attachment of labels, papers, boxes, cards, etc. by means of snap-in, snap or clamp connections. The scope of design for packaging developers is almost limitless.

Of course, it is also possible to design the instructions for use as a separate sheet, which is placed in the packaging. This embodiment is again recommended in kits according to the invention, which have an additional outer packaging. The separate instructions for use can be made on paper, cardboard, plastic, etc. in the form of sheets, sheets, cards, cards, flyers, fanfolds, etc. The separate instructions for use has the advantage that the consumer can fix them in an exposed position and read repeatedly when using the agent. Also, such a separate instruction manual can be taken out of the packaging and read several times in changing places, without always the complete kit must be carried.

Kits according to the invention, in which the instructions for use are designed as a separate supplement, are a further preferred embodiment of the present invention.

The instructions for use preferably lead the consumer to use the method according to the invention.

With regard to preferred methods according to the invention, what has been said about the mouthwash compositions according to the invention applies mutatis mutandis.

When used in the context of the process according to the invention, the compositions according to the invention lead to a number of consumer benefits, the list below not being exhaustive. Particular preference is given to the use of ready-to-use mouthwash compositions according to the invention for whitening teeth and teeth and / or for cleaning the oral cavity and / or for reducing plaque and / or for preventing and / or reducing bad breath and / or prophylactic caries prevention and / or or for prophylactic prevention of gingivitis and / or prophylactic prevention of periodontitis and / or prophylactic prevention of aphthous ulcers and / or prophylactic prevention of bite irritation and / or prophylactic prevention of mucosal infections and / or for prophylactic prevention of herpes stomatitis.

Also with regard to preferred uses according to the invention, what has been said about the mouthwash compositions according to the invention applies mutatis mutandis.

A third aspect of the invention is the use of at least one sugar alcohol and at least one nonionic surfactant, preferably an ethoxylated nonionic surfactant and in particular an ethoxylated nonionic surfactant having from 30 to 100, preferably 40 to 90 and in particular 50 to 70 EO groups, in the hydrogen peroxide containing phase of a two-phase mouthwash composition, the two phases of which are combined in a sales unit and mixed together before use, for the inhibition and / or reduction of discoloration in the hydrogen peroxide phase.

According to the invention is the use of the sugar alcohol and the nonionic TTeennssiiddss GGUUIIDDEE IInnhhiibbiieerruunngg aanndd // ooddeerr VVeerrrriinnggeerruunngg ooff MMeettaalllliioonneein-related, in particular of Cu ²⁺ - ion induced, discoloration of hydrogen peroxide phase.

The sugar alcohol used is preferably arabitol, xylitol, galactitol, mannitol, sorbitol and / or mixtures thereof, in particular sorbitol.

The use of ethoxylated, hydrogenated castor oil is also preferred according to the invention.

The following example is intended to further define the subject matter of the invention without limiting it thereto. Unless indicated otherwise, the quantities are based on% by weight.

Examples:

Two-phase bleaching mouthwash

Claims

claims:

1. Usable two-phase mouthwash composition consisting of two separately packaged components, which are combined in a sales unit and mixed together before use, characterized in that the first component (A) in addition to an aqueous hydrogen peroxide solution at least one sugar alcohol and at least one or more nonionic (s) surfactant (s), preferably ethoxylated nonionic surfactant (s) and in particular ethoxylated nonionic surfactant (s) having from 30 to 100, preferably 40 to 90, and most preferably 50 to 70, EO Groups, and the second component (B) contains an aqueous or aqueous-alcoholic solution based on one or more substances from the group of surfactants, flavorings and oral hygiene agents.

2. Mouthwash composition according to claim 1, characterized in that the component (A), based on its weight, 0.1 to 20 wt .-%, preferably 0.2 to 15% by weight, particularly preferably 0.5 to 10 Wt .-% and in particular 1 to 5 wt .-% arabitol, xylitol, galactitol, mannitol, sorbitol and / or mixtures thereof.

3. Mouthwash composition according to claim 2, characterized in that component (A) contains sorbitol.

4. Mouthwash composition according to one of claims 1 to 3, characterized in that the component (A), based on its weight, 0.01 to 5 wt .-%, preferably 0.02 to 3 wt .-%, particularly preferably 0 , 05 to 2 wt .-% and in particular 0.08 to 1 wt .-% ethoxylated, hydrogenated castor oil contains.

5. Mouthwash composition according to one of claims 1 to 4, characterized in that the component (A), based on their weight, 0.01 to 10 wt .-%, preferably 0.02 to 5 wt .-% and in particular 0, Contains from 05 to 2 wt .-% hydrogen peroxide.

6. Mouthwash composition according to one of claims 1 to 5, characterized in that the component (B) additionally anti-caries agents, preferably fluorine compound (s), in particular sodium fluoride, potassium fluoride, sodium monofluorophosphate, zinc fluoride, stannous fluoride and sodium fluorosilicate, preferably in amounts of 0, 01 to 2.5 wt.%, Preferably from 0.02 to 1 wt.% And in particular from 0.03 to 0.5 wt.%, Each based on the total agent contains.

7. Mouthwash composition according to one of claims 1 to 6, characterized in that the component (B) in addition antiplaque agents, preferably p-hydroxybenzoic acid methyl, ethyl or propyl esters, sodium sorbate, sodium benzoate, bromochlorophene, triclosan, phenyl salicylates, biguanides z. As chlorhexidine, thymol, preferably in amounts of 0.01 to 2.5 wt.%, Preferably from 0.05 to 1 wt.% And in particular from 0.1 to 0.5 wt.%, Each based on the total Means containing.

8. A method for cleaning the oral cavity, characterized in that a ready-to-use mouthwash composition according to any one of claims 1 to 7 is introduced undiluted into the oral cavity and removed after a contact time again from her.

9. Use of a ready-to-use mouthwash composition according to any one of claims 1 to 8 for teeth and teeth whitening and / or for cleaning the oral cavity and / or for reducing plaque and / or for preventing and / or reducing bad breath and / or prophylactic prophylaxis against caries and / or prophylactic prevention of gingivitis and / or prophylactic prevention of periodontitis and / or prophylactic prevention of aphthae and / or prophylactic prevention of bite irritation and / or prophylactic prevention of mucosal infections and / or prophylactic prevention of herpes stomatitis.

10. Use of a mixture of at least one sugar alcohol and at least one nonionic surfactant, preferably ethoxylated nonionic surfactant and in particular ethoxylated nonionic surfactant having 30 to 100, preferably 40 to 90 and in particular 50 to 70 EO groups, in the hydrogen peroxide-containing phase of a biphasic Mouthwash composition, the two phases of which are combined in a sales unit and mixed together before use, for the inhibition and / or reduction of discoloration in the hydrogen peroxide phase.

11. Use according to claim 10, characterized in that metal ion-induced discoloration of the hydrogen peroxide phase is inhibited and / or reduced.

Use according to any one of claims 10 or 11 for inhibiting and / or reducing the presence of hydrogen peroxide phase stains caused by Cu ²⁺ ions.

13. Use according to any one of claims 10 to 12, characterized in that the sugar alcohol is selected from arabitol, xylitol, galactitol, mannitol, sorbitol and / or mixtures thereof.

14. Use according to claim 13, characterized in that the sugar alcohol is sorbitol.

15. Use according to any one of claims 10 to 14, characterized in that the nonionic surfactant is ethoxylated, hydrogenated castor oil.