WO2008044028A3 - Labelling groups - Google Patents

Labelling groups Download PDF

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Publication number
WO2008044028A3
WO2008044028A3 PCT/GB2007/003863 GB2007003863W WO2008044028A3 WO 2008044028 A3 WO2008044028 A3 WO 2008044028A3 GB 2007003863 W GB2007003863 W GB 2007003863W WO 2008044028 A3 WO2008044028 A3 WO 2008044028A3
Authority
WO
WIPO (PCT)
Prior art keywords
formula
labelling groups
nucleic acid
labelling
groups
Prior art date
Application number
PCT/GB2007/003863
Other languages
French (fr)
Other versions
WO2008044028A2 (en
Inventor
Richard Gilbert
Original Assignee
E2V Biosensors Ltd
Richard Gilbert
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by E2V Biosensors Ltd, Richard Gilbert filed Critical E2V Biosensors Ltd
Publication of WO2008044028A2 publication Critical patent/WO2008044028A2/en
Publication of WO2008044028A3 publication Critical patent/WO2008044028A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Abstract

Raman-active nucleobase analogues and their use for the detection of nucleic acid analytes and nucleic acid sequencing are described: Formula (A), Formula (G), Formula (C), Formula (T).
PCT/GB2007/003863 2006-10-11 2007-10-11 Labelling groups WO2008044028A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0620198A GB0620198D0 (en) 2006-10-11 2006-10-11 Labelling groups
GB0620198.2 2006-10-11

Publications (2)

Publication Number Publication Date
WO2008044028A2 WO2008044028A2 (en) 2008-04-17
WO2008044028A3 true WO2008044028A3 (en) 2008-08-07

Family

ID=37491345

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2007/003863 WO2008044028A2 (en) 2006-10-11 2007-10-11 Labelling groups

Country Status (2)

Country Link
GB (1) GB0620198D0 (en)
WO (1) WO2008044028A2 (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5405747A (en) * 1991-09-25 1995-04-11 The Regents Of The University Of California Office Of Technology Transfer Method for rapid base sequencing in DNA and RNA with two base labeling
WO1997005280A1 (en) * 1995-07-25 1997-02-13 University Of Strathclyde Detection of nucleic acids and nucleic acid units
US6136543A (en) * 1997-01-31 2000-10-24 Hitachi, Ltd. Method for determining nucleic acids base sequence and apparatus therefor
WO2003078649A2 (en) * 2002-03-14 2003-09-25 Intel Corporation Methods to increase nucleotide signals by raman scattering
US20060147941A1 (en) * 2004-12-30 2006-07-06 Intel Corporation Methods and apparatus for SERS assay of biological analytes

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5405747A (en) * 1991-09-25 1995-04-11 The Regents Of The University Of California Office Of Technology Transfer Method for rapid base sequencing in DNA and RNA with two base labeling
WO1997005280A1 (en) * 1995-07-25 1997-02-13 University Of Strathclyde Detection of nucleic acids and nucleic acid units
US6136543A (en) * 1997-01-31 2000-10-24 Hitachi, Ltd. Method for determining nucleic acids base sequence and apparatus therefor
WO2003078649A2 (en) * 2002-03-14 2003-09-25 Intel Corporation Methods to increase nucleotide signals by raman scattering
US20060147941A1 (en) * 2004-12-30 2006-07-06 Intel Corporation Methods and apparatus for SERS assay of biological analytes

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BEUKERS MARGOT W ET AL: "N6-cyclopentyl-2-(3-phenylaminocarbonyltriazene-1-yl)adenosine (TCPA), a very selective agonist with high affinity for the human adenosine A1 receptor.", JOURNAL OF MEDICINAL CHEMISTRY, vol. 46, no. 8, 10 April 2003 (2003-04-10), pages 1492 - 1503, XP002479003, ISSN: 0022-2623 *
CHIN A ET AL: "Reactions of Benzenediazonium Ions with Adenine and Its Derivatives", JOURNAL OF ORGANIC CHEMISTRY, AMERICAN CHEMICAL SOCIETY. EASTON, US, vol. 46, no. 11, 1 January 1981 (1981-01-01), pages 2203 - 2207, XP002338153, ISSN: 0022-3263 *
COATES C G ET AL: "Transient resonance Raman investigation of excited states of [Ru(phen)2dppz]2Y and deuterated analogues in aqueous and non-aqueous environments", JOURNAL OF RAMAN SPECTROSCOPY, XX, XX, vol. 31, 1 January 2000 (2000-01-01), pages 283 - 288, XP002434157 *
KUBOTA M ET AL: "DNA-based aromatic zipper fastened by an aromatic stacking interaction", TETRAHEDRON LETTERS, ELSEVIER, AMSTERDAM, NL, vol. 45, no. 29, 12 July 2004 (2004-07-12), pages 5755 - 5758, XP004516575, ISSN: 0040-4039 *
LIN J-K ET AL: "N SUBSTITUTION OF CARBON 8 IN GUANOSINE AND DEOXY GUANOSINE BY THE CARCINOGEN N BENZOYLOXY-N-METHYL-4-AMINO AZO BENZENE IN-VITRO", CANCER RESEARCH, vol. 35, no. 3, 1975, pages 832 - 843, XP002479002, ISSN: 0008-5472 *

Also Published As

Publication number Publication date
WO2008044028A2 (en) 2008-04-17
GB0620198D0 (en) 2006-11-22

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