WO2008039299A2 - Three diode optical bridge system - Google Patents
Three diode optical bridge system Download PDFInfo
- Publication number
- WO2008039299A2 WO2008039299A2 PCT/US2007/019635 US2007019635W WO2008039299A2 WO 2008039299 A2 WO2008039299 A2 WO 2008039299A2 US 2007019635 W US2007019635 W US 2007019635W WO 2008039299 A2 WO2008039299 A2 WO 2008039299A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- sample
- radiation
- target analyte
- wavelength
- wavelengths
- Prior art date
Links
- 230000003287 optical effect Effects 0.000 title description 33
- 238000005259 measurement Methods 0.000 claims abstract description 45
- 238000000034 method Methods 0.000 claims abstract description 41
- 239000012491 analyte Substances 0.000 claims abstract description 39
- 230000005855 radiation Effects 0.000 claims abstract description 32
- 239000012530 fluid Substances 0.000 claims abstract description 28
- 239000008280 blood Substances 0.000 claims abstract description 24
- 210000004369 blood Anatomy 0.000 claims abstract description 24
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 13
- 239000008103 glucose Substances 0.000 claims abstract description 13
- 230000005670 electromagnetic radiation Effects 0.000 claims abstract description 12
- 238000010521 absorption reaction Methods 0.000 claims abstract description 11
- 239000011159 matrix material Substances 0.000 claims description 15
- 239000000203 mixture Substances 0.000 claims description 4
- 230000003252 repetitive effect Effects 0.000 claims description 4
- 230000005540 biological transmission Effects 0.000 claims description 3
- 239000000523 sample Substances 0.000 abstract description 112
- 230000006835 compression Effects 0.000 description 15
- 238000007906 compression Methods 0.000 description 15
- 230000008569 process Effects 0.000 description 12
- 230000008901 benefit Effects 0.000 description 6
- 230000007246 mechanism Effects 0.000 description 6
- 230000008859 change Effects 0.000 description 5
- 230000004075 alteration Effects 0.000 description 4
- 230000006872 improvement Effects 0.000 description 4
- 102000001554 Hemoglobins Human genes 0.000 description 3
- 108010054147 Hemoglobins Proteins 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 230000000747 cardiac effect Effects 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000004941 influx Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000003071 parasitic effect Effects 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- 230000001360 synchronised effect Effects 0.000 description 2
- 239000013076 target substance Substances 0.000 description 2
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 230000008033 biological extinction Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 210000000624 ear auricle Anatomy 0.000 description 1
- 238000011067 equilibration Methods 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 210000000492 nasalseptum Anatomy 0.000 description 1
- 229960002715 nicotine Drugs 0.000 description 1
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000007781 pre-processing Methods 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000003595 spectral effect Effects 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 210000003371 toe Anatomy 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/314—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
- G01N21/3151—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths using two sources of radiation of different wavelengths
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
Definitions
- the result is a substantially straight line whose slope is directly related to the concentration of analyte in the sample, assuming that the other factors contributing to the "parasitic" signal, including shifts in the effective wavelength due to changes in sample thickness, remain relatively constant during the measurement process.
Abstract
Description
Claims
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07811716A EP2073697A2 (en) | 2006-09-25 | 2007-09-10 | Three diode optical bridge system |
CN2007800354593A CN101605493B (en) | 2006-09-25 | 2007-09-10 | Three diode optical bridge system |
AU2007300695A AU2007300695B2 (en) | 2006-09-25 | 2007-09-10 | Three diode optical bridge system |
CA2700133A CA2700133C (en) | 2006-09-25 | 2007-09-10 | Three diode optical bridge system |
JP2009529183A JP5723098B2 (en) | 2006-09-25 | 2007-09-10 | Method and system for measuring substance concentration using electromagnetic radiation beam |
IL197589A IL197589A (en) | 2006-09-25 | 2009-03-12 | Three diode optical bridge system |
HK10106047.8A HK1139294A1 (en) | 2006-09-25 | 2010-06-17 | Three diode optical bridge system |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/526,564 | 2006-09-25 | ||
US11/526,564 US8175666B2 (en) | 2002-04-26 | 2006-09-25 | Three diode optical bridge system |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008039299A2 true WO2008039299A2 (en) | 2008-04-03 |
WO2008039299A3 WO2008039299A3 (en) | 2008-05-29 |
Family
ID=39146866
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2007/019635 WO2008039299A2 (en) | 2006-09-25 | 2007-09-10 | Three diode optical bridge system |
Country Status (10)
Country | Link |
---|---|
US (1) | US8175666B2 (en) |
EP (1) | EP2073697A2 (en) |
JP (1) | JP5723098B2 (en) |
KR (1) | KR101597310B1 (en) |
CN (1) | CN101605493B (en) |
AU (1) | AU2007300695B2 (en) |
CA (1) | CA2700133C (en) |
HK (1) | HK1139294A1 (en) |
IL (1) | IL197589A (en) |
WO (1) | WO2008039299A2 (en) |
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WO2013160780A1 (en) * | 2012-04-23 | 2013-10-31 | I.R.Med Ltd. | Short-wave infrared imaging and spectroscopy technique for inflammation classification and tumor and inflammation differentiation in human tissues inside the body |
WO2016027274A1 (en) * | 2014-08-21 | 2016-02-25 | I.R Med Ltd | System and method for noninvasive analysis of tissue |
US10709365B2 (en) | 2014-08-21 | 2020-07-14 | I. R. Med Ltd. | System and method for noninvasive analysis of subcutaneous tissue |
US10772541B2 (en) | 2014-08-21 | 2020-09-15 | I. R. Med Ltd. | System and method for noninvasive analysis of subcutaneous tissue |
US11129556B2 (en) | 2015-12-31 | 2021-09-28 | Wear2B Ltd. | Device, system and method for non-invasive monitoring of physiological measurements |
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JP5398009B2 (en) * | 2010-03-17 | 2014-01-29 | 学校法人北里研究所 | Optical coherence tomography apparatus and tomographic imaging method |
JP5990508B2 (en) * | 2011-03-31 | 2016-09-14 | テルモ株式会社 | Blood component measuring device |
EP2543839A1 (en) * | 2011-07-04 | 2013-01-09 | Inergy Automotive Systems Research (Société Anonyme) | Device for measuring the concentration of urea |
US20130267799A1 (en) * | 2012-04-06 | 2013-10-10 | Hannu Harjunmaa | Noninvasive measurement of analyte concentration using a fiberless transflectance probe |
JP5859414B2 (en) * | 2012-10-16 | 2016-02-10 | 株式会社 堀場アドバンスドテクノ | Color meter |
US10458280B2 (en) * | 2013-03-13 | 2019-10-29 | United Technologies Corporation | Gas turbine engine hydraulically operated nacelle latch |
CA2951323A1 (en) * | 2013-06-16 | 2014-12-24 | Ulrik Merrild NIELSEN | Detection of indications of psychoactive components in a liquid |
US9322716B2 (en) * | 2014-01-07 | 2016-04-26 | Panasonic Intellectual Property Corporation Of America | Component measuring apparatus and moving body |
WO2015177867A1 (en) * | 2014-05-20 | 2015-11-26 | パイオニア株式会社 | Pulse oximeter |
US9459201B2 (en) | 2014-09-29 | 2016-10-04 | Zyomed Corp. | Systems and methods for noninvasive blood glucose and other analyte detection and measurement using collision computing |
WO2017029792A1 (en) * | 2015-08-18 | 2017-02-23 | 国立大学法人徳島大学 | Concentration measurement device |
CN105249974A (en) * | 2015-10-15 | 2016-01-20 | 华南师范大学 | Pressure-modulation-spectrum-technology-based noninvasive glucose detection system and method |
CN105784591A (en) * | 2015-12-26 | 2016-07-20 | 深圳市前海安测信息技术有限公司 | Blood glucose test data acquisition system and method |
US10088468B2 (en) | 2016-02-04 | 2018-10-02 | Nova Biomedical Corporation | Analyte system and method for determining hemoglobin parameters in whole blood |
US9554738B1 (en) | 2016-03-30 | 2017-01-31 | Zyomed Corp. | Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing |
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- 2007-09-10 JP JP2009529183A patent/JP5723098B2/en not_active Expired - Fee Related
- 2007-09-10 WO PCT/US2007/019635 patent/WO2008039299A2/en active Application Filing
- 2007-09-10 AU AU2007300695A patent/AU2007300695B2/en not_active Ceased
- 2007-09-10 EP EP07811716A patent/EP2073697A2/en not_active Withdrawn
- 2007-09-10 CA CA2700133A patent/CA2700133C/en not_active Expired - Fee Related
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WO2013160780A1 (en) * | 2012-04-23 | 2013-10-31 | I.R.Med Ltd. | Short-wave infrared imaging and spectroscopy technique for inflammation classification and tumor and inflammation differentiation in human tissues inside the body |
WO2016027274A1 (en) * | 2014-08-21 | 2016-02-25 | I.R Med Ltd | System and method for noninvasive analysis of tissue |
US10709365B2 (en) | 2014-08-21 | 2020-07-14 | I. R. Med Ltd. | System and method for noninvasive analysis of subcutaneous tissue |
US10772541B2 (en) | 2014-08-21 | 2020-09-15 | I. R. Med Ltd. | System and method for noninvasive analysis of subcutaneous tissue |
US11129556B2 (en) | 2015-12-31 | 2021-09-28 | Wear2B Ltd. | Device, system and method for non-invasive monitoring of physiological measurements |
Also Published As
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US20070208238A1 (en) | 2007-09-06 |
EP2073697A2 (en) | 2009-07-01 |
AU2007300695B2 (en) | 2012-10-04 |
US8175666B2 (en) | 2012-05-08 |
KR101597310B1 (en) | 2016-02-24 |
WO2008039299A3 (en) | 2008-05-29 |
IL197589A0 (en) | 2009-12-24 |
AU2007300695A1 (en) | 2008-04-03 |
JP5723098B2 (en) | 2015-05-27 |
IL197589A (en) | 2014-12-31 |
HK1139294A1 (en) | 2010-09-17 |
CA2700133A1 (en) | 2008-04-03 |
JP2010504148A (en) | 2010-02-12 |
CN101605493B (en) | 2012-03-14 |
KR20090086202A (en) | 2009-08-11 |
CA2700133C (en) | 2016-05-10 |
CN101605493A (en) | 2009-12-16 |
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