WO2008031231A8 - Accommodative intra-ocular lens - Google Patents

Accommodative intra-ocular lens Download PDF

Info

Publication number
WO2008031231A8
WO2008031231A8 PCT/CA2007/001659 CA2007001659W WO2008031231A8 WO 2008031231 A8 WO2008031231 A8 WO 2008031231A8 CA 2007001659 W CA2007001659 W CA 2007001659W WO 2008031231 A8 WO2008031231 A8 WO 2008031231A8
Authority
WO
WIPO (PCT)
Prior art keywords
lens
anterior
internal fluid
posterior
contraction
Prior art date
Application number
PCT/CA2007/001659
Other languages
French (fr)
Other versions
WO2008031231A1 (en
Inventor
Elie Khoury
Original Assignee
Elie Khoury
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elie Khoury filed Critical Elie Khoury
Priority to US12/441,196 priority Critical patent/US8070806B2/en
Priority to EP07815852A priority patent/EP2056749A4/en
Publication of WO2008031231A1 publication Critical patent/WO2008031231A1/en
Publication of WO2008031231A8 publication Critical patent/WO2008031231A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1624—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside
    • A61F2/1635—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside for changing shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1624—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside
    • A61F2/1629—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside for changing longitudinal position, i.e. along the visual axis when implanted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1648—Multipart lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0036—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in thickness

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

An accommodative intra-ocular lens 10 deformable between the unaccommodating and accommodating configurations respectively upon the relaxation and contraction of the ciliary muscle 28. The lens includes an anterior portion and a posterior portion 32, 34. The lens anterior and posterior portions 32, 34 are substantially sealingly joined together about their respective anterior and posterior portion peripheral edges 48, 54 and define a lens internal volume filled with a substantially incompressible lens internal fluid 58. The lens internal fluid defines a variable internal fluid pressure exerted on the anterior and posterior portion inner surfaces. The lens 10 is configured such that radius of curvature of both the central and peripheral sections 44, 46 of the lens anterior portion will decrease upon an increase in internal fluid pressure and increase upon a decrease in internal fluid pressure. In a first embodiment, the main actuating effect is the increase in vitreous humor pressure caused by the contraction of the ciliary muscle 28 and transmitted to the internal fluid 58 by the lens posterior portion 34. In a second embodiment, the main actuating effect is the decrease in circumlenticular space caused by the contraction of the ciliary muscle 28 that is converted by haptics 82 into a movement of the anterior and posterior lens portions 32, 34 towards each other. In both cases the contraction of the ciliary muscle 28 eventually causes an increase in internal fluid pressure that deforms the lens anterior portion 32 towards the accommodated configuration. In both cases, the configuration of the lens anterior portion is such that refractive aberrations are minimized substantially throughout the range of accommodation.
PCT/CA2007/001659 2006-09-16 2007-09-17 Accommodative intra-ocular lens WO2008031231A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US12/441,196 US8070806B2 (en) 2006-09-16 2007-09-17 Accommodative intra-ocular lens
EP07815852A EP2056749A4 (en) 2006-09-16 2007-09-17 Accommodative intra-ocular lens

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0618262.0 2006-09-16
GBGB0618262.0A GB0618262D0 (en) 2006-09-16 2006-09-16 Accommodative intra-ocular lens

Publications (2)

Publication Number Publication Date
WO2008031231A1 WO2008031231A1 (en) 2008-03-20
WO2008031231A8 true WO2008031231A8 (en) 2011-08-11

Family

ID=37310050

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2007/001659 WO2008031231A1 (en) 2006-09-16 2007-09-17 Accommodative intra-ocular lens

Country Status (4)

Country Link
US (1) US8070806B2 (en)
EP (1) EP2056749A4 (en)
GB (1) GB0618262D0 (en)
WO (1) WO2008031231A1 (en)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
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US10835373B2 (en) 2002-12-12 2020-11-17 Alcon Inc. Accommodating intraocular lenses and methods of use
US8328869B2 (en) 2002-12-12 2012-12-11 Powervision, Inc. Accommodating intraocular lenses and methods of use
US8361145B2 (en) 2002-12-12 2013-01-29 Powervision, Inc. Accommodating intraocular lens system having circumferential haptic support and method
IL161706A0 (en) 2004-04-29 2004-09-27 Nulens Ltd Intraocular lens fixation device
US9872763B2 (en) 2004-10-22 2018-01-23 Powervision, Inc. Accommodating intraocular lenses
CN101203192B (en) 2005-03-30 2010-09-15 纽镜有限公司 Adjustable intraocular lens assemblies and discrete components thereof
ES2653845T3 (en) 2006-01-17 2018-02-09 Novartis Ag Drug administration treatment device
US9610155B2 (en) 2008-07-23 2017-04-04 Powervision, Inc. Intraocular lens loading systems and methods of use
US8968396B2 (en) 2007-07-23 2015-03-03 Powervision, Inc. Intraocular lens delivery systems and methods of use
EP2178462B1 (en) 2007-07-23 2014-04-02 PowerVision, Inc. Post-implant lens power modification
US8668734B2 (en) 2010-07-09 2014-03-11 Powervision, Inc. Intraocular lens delivery devices and methods of use
EP2671541B1 (en) 2007-07-23 2019-04-17 PowerVision, Inc. Accommodating intraocular lenses
US8414646B2 (en) 2007-12-27 2013-04-09 Forsight Labs, Llc Intraocular, accommodating lens and methods of use
EP3381407A1 (en) 2008-01-03 2018-10-03 Forsight Labs, Llc Intraocular, accomodating lens and methods of use
US10299913B2 (en) 2009-01-09 2019-05-28 Powervision, Inc. Accommodating intraocular lenses and methods of use
JP2013520291A (en) 2010-02-23 2013-06-06 パワーヴィジョン・インコーポレーテッド Liquid for accommodation type intraocular lens
WO2011137191A1 (en) 2010-04-27 2011-11-03 Ramgopal Rao Accommodating intraocular lens device
US9220590B2 (en) 2010-06-10 2015-12-29 Z Lens, Llc Accommodative intraocular lens and method of improving accommodation
WO2012106673A1 (en) 2011-02-04 2012-08-09 Forsight Labs, Llc Intraocular accommodating lens
US9186243B2 (en) 2011-05-31 2015-11-17 Novartis Ag Accommodative intraocular lens and method of implantation
US10433949B2 (en) 2011-11-08 2019-10-08 Powervision, Inc. Accommodating intraocular lenses
US9364318B2 (en) 2012-05-10 2016-06-14 Z Lens, Llc Accommodative-disaccommodative intraocular lens
DE102012016893A1 (en) 2012-08-24 2014-05-15 Be Innovative Gmbh Intraocular lens, in particular capsular bag intraocular lens
ES2457840B1 (en) * 2012-09-28 2015-02-16 Universidad De Murcia Variable power accommodative intraocular lens and variable power accommodative intraocular lens set and capsular ring
WO2014070331A1 (en) * 2012-10-31 2014-05-08 Novartis Ag Accommodating intraocular lens with ciliary body activation
US9186244B2 (en) 2012-12-21 2015-11-17 Lensgen, Inc. Accommodating intraocular lens
JP6717740B2 (en) 2013-03-15 2020-07-01 パワーヴィジョン・インコーポレーテッド Device for accommodating and placing intraocular lens and method of using the same
CN109806027A (en) 2013-11-01 2019-05-28 雷恩斯根公司 Double component modulability intraocular lens equipment
WO2015066502A1 (en) 2013-11-01 2015-05-07 Thomas Silvestrini Accomodating intraocular lens device
EP3791827B8 (en) 2014-03-28 2024-02-14 ForSight Vision6, Inc. Accommodating intraocular lens
US9333072B2 (en) * 2014-04-29 2016-05-10 Chukyo Medical Co., Inc. Intraocular lens
US10004596B2 (en) 2014-07-31 2018-06-26 Lensgen, Inc. Accommodating intraocular lens device
JP6754755B2 (en) 2014-09-23 2020-09-16 レンスゲン、インコーポレイテッド Polymeric material for adjustable intraocular lenses
JP6660640B2 (en) 2015-02-16 2020-03-11 アルコン インコーポレイティド Adjustable curvature intraocular lens with inflatable peripheral reservoir
CN108348328B (en) 2015-11-06 2020-04-10 力景公司 Accommodating intraocular lens and method of manufacture
CN113180886A (en) 2015-12-01 2021-07-30 雷恩斯根公司 Accommodating intraocular lens device
JP2019519664A (en) 2016-05-27 2019-07-11 レンズジェン、インコーポレイテッド Narrow molecular weight distribution lens oil for intraocular lens devices
US10512535B2 (en) 2016-08-24 2019-12-24 Z Lens, Llc Dual mode accommodative-disaccomodative intraocular lens
EA037705B1 (en) 2016-10-28 2021-05-12 Форсайт Вижн6, Инк. Accommodating intraocular lens and system for implantation in an eye
KR102306886B1 (en) * 2019-10-18 2021-09-30 주식회사 로섹 Intraocular lens

Family Cites Families (8)

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US4253199A (en) 1978-09-25 1981-03-03 Surgical Design Corporation Surgical method and apparatus for implants for the eye
US4932966A (en) * 1988-08-15 1990-06-12 Storz Instrument Company Accommodating intraocular lens
US6638305B2 (en) 2001-05-15 2003-10-28 Advanced Medical Optics, Inc. Monofocal intraocular lens convertible to multifocal intraocular lens
FR2835424B1 (en) 2002-02-01 2004-11-26 Khalil Hanna ACCOMODATIVE INTRACAPSULAR IMPLANT
US7261737B2 (en) * 2002-12-12 2007-08-28 Powervision, Inc. Accommodating intraocular lens system and method
US20050137703A1 (en) * 2003-12-05 2005-06-23 Vanderbilt University Accommodative intraocular lens
US9713527B2 (en) * 2004-04-30 2017-07-25 Rxsight, Inc. Multilens intraocular lens system with injectable accommodation material
US7981155B2 (en) 2005-12-07 2011-07-19 C&C Vision International Limited Hydrolic accommodating intraocular lens

Also Published As

Publication number Publication date
EP2056749A4 (en) 2013-02-27
US8070806B2 (en) 2011-12-06
EP2056749A1 (en) 2009-05-13
WO2008031231A1 (en) 2008-03-20
US20090319040A1 (en) 2009-12-24
GB0618262D0 (en) 2006-10-25

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