WO2008030558A2 - Modified human plasma polypeptide or fc scaffolds and their uses - Google Patents
Modified human plasma polypeptide or fc scaffolds and their uses Download PDFInfo
- Publication number
- WO2008030558A2 WO2008030558A2 PCT/US2007/019528 US2007019528W WO2008030558A2 WO 2008030558 A2 WO2008030558 A2 WO 2008030558A2 US 2007019528 W US2007019528 W US 2007019528W WO 2008030558 A2 WO2008030558 A2 WO 2008030558A2
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- Prior art keywords
- polypeptide
- hpp
- amino acid
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- substituted
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Abstract
Description
Claims
Priority Applications (17)
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JP2009527426A JP5840345B2 (en) | 2006-09-08 | 2007-09-07 | Modified human plasma polypeptides or modified human Fc scaffold proteins and uses thereof |
MX2009002523A MX2009002523A (en) | 2006-09-08 | 2007-09-07 | Modified human plasma polypeptide or fc scaffolds and their uses. |
AU2007292903A AU2007292903B2 (en) | 2006-09-08 | 2007-09-07 | Modified human plasma polypeptide or Fc scaffolds and their uses |
EP07837882.5A EP2069396B1 (en) | 2006-09-08 | 2007-09-07 | Modified human plasma polypeptide or fc scaffolds and their uses |
CA002663083A CA2663083A1 (en) | 2006-09-08 | 2007-09-07 | Modified human plasma polypeptide or fc scaffolds and their uses |
US12/440,010 US8618257B2 (en) | 2006-09-08 | 2007-09-07 | Modified human plasma polypeptide or Fc scaffolds and their uses |
US11/927,139 US8022186B2 (en) | 2006-09-08 | 2007-10-29 | Modified human plasma polypeptide or Fc scaffolds and their uses |
US11/927,247 US8053560B2 (en) | 2006-09-08 | 2007-10-29 | Modified human plasma polypeptide or Fc scaffolds and their uses |
US11/927,283 US7919591B2 (en) | 2006-09-08 | 2007-10-29 | Modified human plasma polypeptide or Fc scaffolds and their uses |
IL196892A IL196892A (en) | 2006-09-08 | 2009-02-04 | Modified human plasma polypeptide or fc scaffolds and their uses |
HK09111623.3A HK1134302A1 (en) | 2006-09-08 | 2009-12-10 | Modified human plasma polypeptide or fc scaffolds and their uses fc |
US13/035,719 US20110207914A1 (en) | 2006-09-08 | 2011-02-25 | Modified Human Plasma Polypeptide or Fc Scaffolds and Their Uses |
US13/184,889 US20120041180A1 (en) | 2006-09-08 | 2011-07-18 | Modified Human Plasma Polypeptide or Fc Scaffolds and Their Uses |
US13/208,136 US9074010B2 (en) | 2006-09-08 | 2011-08-11 | Modified human plasma polypeptide or Fc scaffolds and their uses |
IL222515A IL222515A (en) | 2006-09-08 | 2012-10-18 | Mutant human albumin comprising non-natural amino acids |
IL226324A IL226324A (en) | 2006-09-08 | 2013-05-13 | Modified human serum albumin |
US14/088,328 US20140296487A1 (en) | 2006-09-08 | 2013-11-22 | Modified Human Plasma Polypeptide or Fc Scaffolds and Their Uses |
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US84321506P | 2006-09-08 | 2006-09-08 | |
US60/843,215 | 2006-09-08 | ||
US92848507P | 2007-05-08 | 2007-05-08 | |
US60/928,485 | 2007-05-08 |
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US12/440,010 A-371-Of-International US8618257B2 (en) | 2006-09-08 | 2007-09-07 | Modified human plasma polypeptide or Fc scaffolds and their uses |
US11/927,247 Continuation US8053560B2 (en) | 2006-09-08 | 2007-10-29 | Modified human plasma polypeptide or Fc scaffolds and their uses |
US11/927,139 Continuation US8022186B2 (en) | 2006-09-08 | 2007-10-29 | Modified human plasma polypeptide or Fc scaffolds and their uses |
US11/927,283 Continuation US7919591B2 (en) | 2006-09-08 | 2007-10-29 | Modified human plasma polypeptide or Fc scaffolds and their uses |
US14/088,328 Division US20140296487A1 (en) | 2006-09-08 | 2013-11-22 | Modified Human Plasma Polypeptide or Fc Scaffolds and Their Uses |
Publications (2)
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WO2008030558A2 true WO2008030558A2 (en) | 2008-03-13 |
WO2008030558A3 WO2008030558A3 (en) | 2008-11-13 |
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PCT/US2007/019528 WO2008030558A2 (en) | 2006-09-08 | 2007-09-07 | Modified human plasma polypeptide or fc scaffolds and their uses |
Country Status (12)
Country | Link |
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US (8) | US8618257B2 (en) |
EP (2) | EP2615108B1 (en) |
JP (1) | JP5840345B2 (en) |
KR (1) | KR20090060294A (en) |
CN (2) | CN106008699A (en) |
AU (1) | AU2007292903B2 (en) |
CA (1) | CA2663083A1 (en) |
DK (1) | DK2615108T3 (en) |
HK (1) | HK1134302A1 (en) |
IL (3) | IL196892A (en) |
MX (1) | MX2009002523A (en) |
WO (1) | WO2008030558A2 (en) |
Cited By (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014004639A1 (en) * | 2012-06-26 | 2014-01-03 | Sutro Biopharma, Inc. | Modified fc proteins comprising site-specific non-natural amino acid residues, conjugates of the same, methods of their preparation and methods of their use |
WO2014036492A1 (en) * | 2012-08-31 | 2014-03-06 | Sutro Biopharma, Inc. | Modified amino acids comprising an azido group |
US20140315816A1 (en) * | 2011-05-05 | 2014-10-23 | Novozymes Biopharma Dk A/S | Albumin variants |
US8927694B2 (en) | 2008-11-18 | 2015-01-06 | Merrimack Pharmaceuticals, Inc. | Human serum albumin linkers and conjugates thereof |
EP2819702A4 (en) * | 2012-02-29 | 2015-05-20 | Ambrx Inc | Novel prodrug containing molecule compostions and their uses |
WO2015191892A2 (en) | 2014-06-11 | 2015-12-17 | Beth Israel Deaconess Medical Center, Inc. | α1-ANTITRYPSIN COMPOSITIONS AND METHODS OF TREATING AUTOIMMUNE DISEASES |
US9266939B2 (en) | 2010-12-27 | 2016-02-23 | Alexion Pharmaceuticals, Inc. | Compositions comprising natriuretic peptides and methods of use thereof |
US9345766B2 (en) | 2012-08-30 | 2016-05-24 | Merrimack Pharmaceuticals, Inc. | Combination therapies comprising anti-ERBB3 agents |
US9738724B2 (en) | 2012-06-08 | 2017-08-22 | Sutro Biopharma, Inc. | Antibodies comprising site-specific non-natural amino acid residues, methods of their preparation and methods of their use |
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2011
- 2011-02-25 US US13/035,719 patent/US20110207914A1/en not_active Abandoned
- 2011-07-18 US US13/184,889 patent/US20120041180A1/en not_active Abandoned
- 2011-08-11 US US13/208,136 patent/US9074010B2/en not_active Expired - Fee Related
-
2012
- 2012-10-18 IL IL222515A patent/IL222515A/en active IP Right Grant
-
2013
- 2013-05-13 IL IL226324A patent/IL226324A/en active IP Right Grant
- 2013-11-22 US US14/088,328 patent/US20140296487A1/en not_active Abandoned
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