WO2008027090A3 - Control of materials and porous magnetic particles - Google Patents

Control of materials and porous magnetic particles Download PDF

Info

Publication number
WO2008027090A3
WO2008027090A3 PCT/US2007/011727 US2007011727W WO2008027090A3 WO 2008027090 A3 WO2008027090 A3 WO 2008027090A3 US 2007011727 W US2007011727 W US 2007011727W WO 2008027090 A3 WO2008027090 A3 WO 2008027090A3
Authority
WO
WIPO (PCT)
Prior art keywords
particles
pores
layer
magnetic
porous magnetic
Prior art date
Application number
PCT/US2007/011727
Other languages
French (fr)
Other versions
WO2008027090A2 (en
Inventor
Michael J Sailor
Ji-Ho Park
Austin M Derfus
Ester Segal
Kenneth S Vecchio
Sangeeta N Bhatia
Original Assignee
Univ California
Michael J Sailor
Ji-Ho Park
Austin M Derfus
Ester Segal
Kenneth S Vecchio
Sangeeta N Bhatia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California, Michael J Sailor, Ji-Ho Park, Austin M Derfus, Ester Segal, Kenneth S Vecchio, Sangeeta N Bhatia filed Critical Univ California
Priority to US12/300,369 priority Critical patent/US8377147B2/en
Publication of WO2008027090A2 publication Critical patent/WO2008027090A2/en
Publication of WO2008027090A3 publication Critical patent/WO2008027090A3/en

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/0036—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties showing low dimensional magnetism, i.e. spin rearrangements due to a restriction of dimensions, e.g. showing giant magnetoresistivity
    • H01F1/0045—Zero dimensional, e.g. nanoparticles, soft nanoparticles for medical/biological use
    • H01F1/0063—Zero dimensional, e.g. nanoparticles, soft nanoparticles for medical/biological use in a non-magnetic matrix, e.g. granular solids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • B01L3/502792—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics for moving individual droplets on a plate, e.g. by locally altering surface tension
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y25/00—Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00457—Dispensing or evacuation of the solid phase support
    • B01J2219/00459—Beads
    • B01J2219/00466—Beads in a slurry
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00495—Means for heating or cooling the reaction vessels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/005—Beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00502—Particles of irregular geometry
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00563—Magnetic means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00572—Chemical means
    • B01J2219/00576—Chemical means fluorophore
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0896—Nanoscaled
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1816—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using induction heating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces

Abstract

The present invention uses externally applied electromagnetic stimulus to control and heat porous magnetic particles and material associated with the particles. The particles contain magnetic material, such as superparamagnetic iron oxide and are associated with a material. Application of a DC magnetic field allows them to be moved with their associated material, and application of an AC RF electromagnetic field allows them to be heated with their associated material. The material can be associated with the particles by being contained in the pores of the particles, or in other cases the particles can adhere to the associated material, which can be an aqueous droplet. The present invention also provides a multi-layer porous magnetic particle. The particle includes a host layer having pores sized to accept magnetic nanoparticles. Magnetic nanoparticles are infused within pores of the host layer. An encoding layer includes pores that define a spectral code. The pores in the encoding layer are sized to substantially exclude the magnetic nanoparticles. The encoding layer can also be a multi-layer, exhibiting, for example, a complex spectral code.
PCT/US2007/011727 2004-07-19 2007-05-16 Control of materials and porous magnetic particles WO2008027090A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US12/300,369 US8377147B2 (en) 2004-07-19 2007-05-16 Control of materials and porous magnetic particles

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80095006P 2006-05-17 2006-05-17
US60/800,950 2006-05-17

Publications (2)

Publication Number Publication Date
WO2008027090A2 WO2008027090A2 (en) 2008-03-06
WO2008027090A3 true WO2008027090A3 (en) 2008-04-24

Family

ID=39136414

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/011727 WO2008027090A2 (en) 2004-07-19 2007-05-16 Control of materials and porous magnetic particles

Country Status (1)

Country Link
WO (1) WO2008027090A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2110175A1 (en) * 2008-03-20 2009-10-21 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Method and device for thermal control of biological and chemical reactions using magnetic particles or magnetic beads and variable magnetic fields
US8247025B2 (en) * 2009-05-19 2012-08-21 Korea University Research And Business Foundation Magnetic nanoparticle fabrication
CN110935496A (en) * 2014-12-31 2020-03-31 雅培制药有限公司 Digital microfluidic dilution apparatus, systems, and related methods

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5512162A (en) * 1992-08-13 1996-04-30 Massachusetts Institute Of Technology Method for photo-forming small shaped metal containing articles from porous precursors
US20040023253A1 (en) * 2001-06-11 2004-02-05 Sandeep Kunwar Device structure for closely spaced electrodes
US20050003098A1 (en) * 1997-08-29 2005-01-06 3M Innovative Properties Company Flash evaporation-plasma coating deposition method
US6924033B2 (en) * 2000-11-28 2005-08-02 W.R. Grace & Co. -Conn. Silica adsorbent on magnetic substrate
US20060063074A1 (en) * 2000-03-24 2006-03-23 Jenson Mark L Thin-film battery having ultra-thin electrolyte

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5512162A (en) * 1992-08-13 1996-04-30 Massachusetts Institute Of Technology Method for photo-forming small shaped metal containing articles from porous precursors
US20050003098A1 (en) * 1997-08-29 2005-01-06 3M Innovative Properties Company Flash evaporation-plasma coating deposition method
US20060063074A1 (en) * 2000-03-24 2006-03-23 Jenson Mark L Thin-film battery having ultra-thin electrolyte
US6924033B2 (en) * 2000-11-28 2005-08-02 W.R. Grace & Co. -Conn. Silica adsorbent on magnetic substrate
US20040023253A1 (en) * 2001-06-11 2004-02-05 Sandeep Kunwar Device structure for closely spaced electrodes

Also Published As

Publication number Publication date
WO2008027090A2 (en) 2008-03-06

Similar Documents

Publication Publication Date Title
Rashid et al. Strontium hexaferrite (SrFe12O19) based composites for hyperthermia applications
MX2016001578A (en) Magnetic or magnetisable pigment particles and optical effect layers.
Ayyappan et al. Effect of surfactant monolayer on reduction of Fe3O4 nanoparticles under vacuum
WO2008005055A3 (en) Nanoparticles containing titanium oxide
EP2990382A4 (en) Magnetic iron oxide nanoparticle powder, process for producing same, thin film of magnetic iron oxide nanoparticles comprising said magnetic iron oxide nanoparticle powder, and process for producing same
MX2014002767A (en) Nanoparticulate phosphate adsorbent on the basis of maghemite or maghemite/magnetite, production and uses thereof.
WO2017131604A3 (en) Magnetic nanoparticles and magnetorheological fluid comprising same
WO2008139690A1 (en) Process for production of ndfeb sintered magnets
MY175221A (en) Magnetic toner
WO2011008737A8 (en) Engineered aerosol particles, and associated methods
WO2008008413A3 (en) Ultra fine nepheline syenite powder and products for using same
NZ590683A (en) Polyurethane enamel based component with a self-healing surface layer, self-healing enamel and coating powder thereof
Sandeep Kumar Magnetic nanoparticles-based biomedical and bioanalytical applications
WO2011001103A3 (en) Polyarylene ether ketone composition for induction welding
Peng et al. Preparation of soft magnetic composites for Fe particles coated with (NiZn) Fe2O4 via microwave treatment
WO2008027090A3 (en) Control of materials and porous magnetic particles
WO2012018209A3 (en) Composite film for preventing forgery, and composite method for preventing forgery
Mirahmadi-Zare et al. Super magnetic nanoparticles NiFe2O4, coated with aluminum–nickel oxide sol-gel lattices to safe, sensitive and selective purification of his-tagged proteins
IL172838A0 (en) Methods for production of metal oxide nano particles with controlled properties and nano particles and preparations produced thereby
WO2011089130A3 (en) Method for producing hollow bodies having enclosed freely displaceable particles
WO2011020573A3 (en) Method for producing dispersions having metal oxide nanoparticles and dispersions produced thereby
Jiménez et al. Enhancing magnetic hyperthermia in ferrite nanoparticles through shape anisotropy and surface hybridization
WO2008089738A3 (en) Ferrous oxide-binding peptides
Mirzaee et al. Synthesis, characterization and Monte Carlo simulation of CoFe2O4/Polyvinylpyrrolidone nanocomposites: The coercivity investigation
WO2017087744A8 (en) Compositions of nanoparticles with radial gradients and methods of use thereof

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07852364

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 12300369

Country of ref document: US

122 Ep: pct application non-entry in european phase

Ref document number: 07852364

Country of ref document: EP

Kind code of ref document: A2