WO2008026048A3 - Stable injectable pharmaceutical compositions of docetaxel - Google Patents

Stable injectable pharmaceutical compositions of docetaxel Download PDF

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Publication number
WO2008026048A3
WO2008026048A3 PCT/IB2007/002495 IB2007002495W WO2008026048A3 WO 2008026048 A3 WO2008026048 A3 WO 2008026048A3 IB 2007002495 W IB2007002495 W IB 2007002495W WO 2008026048 A3 WO2008026048 A3 WO 2008026048A3
Authority
WO
WIPO (PCT)
Prior art keywords
docetaxel
pharmaceutical compositions
injectable pharmaceutical
stable injectable
stable
Prior art date
Application number
PCT/IB2007/002495
Other languages
French (fr)
Other versions
WO2008026048A2 (en
Inventor
Bhaveshkumar Vallabhbhai Patel
Amit Gupta
Bhushan Subhash Yeola
Ranjith K. Kumar
Girish Kumar Jain
Original Assignee
Wockhardt Research Centre
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wockhardt Research Centre filed Critical Wockhardt Research Centre
Publication of WO2008026048A2 publication Critical patent/WO2008026048A2/en
Publication of WO2008026048A3 publication Critical patent/WO2008026048A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof

Abstract

The present invention relates to stable injectable pharmaceutical compositions of docetaxel or salts thereof, comprising a stock solution and a diluent solution, wherein the stock solution comprises docetaxel or salts thereof along with pharmaceutically acceptable excipients and ethanol and the diluent solution essentially consists of water. The present invention also relates to stable injectable pharmaceutical compositions of docetaxel, wherein pH of the injectable compositions is maintained from between about 3 to about 6.
PCT/IB2007/002495 2006-08-31 2007-08-30 Stable injectable pharmaceutical compositions of docetaxel WO2008026048A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN1391/MUM/2006 2006-08-31
IN1384/MUM/2006 2006-08-31
IN1391MU2006 2006-08-31
IN1384MU2006 2006-08-31

Publications (2)

Publication Number Publication Date
WO2008026048A2 WO2008026048A2 (en) 2008-03-06
WO2008026048A3 true WO2008026048A3 (en) 2009-08-27

Family

ID=39136321

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/002495 WO2008026048A2 (en) 2006-08-31 2007-08-30 Stable injectable pharmaceutical compositions of docetaxel

Country Status (1)

Country Link
WO (1) WO2008026048A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8940786B2 (en) 2012-10-01 2015-01-27 Teikoku Pharma Usa, Inc. Non-aqueous taxane nanodispersion formulations and methods of using the same

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010023321A1 (en) * 2008-09-01 2010-03-04 Stragen Pharma S.A. Liquid formulation containing a taxane derivative
EP2204167A1 (en) 2009-01-05 2010-07-07 Azad Pharma AG Pharmaceutical microemulsion for preventing supramolecular aggregation of amphiphilic molecules
KR101074936B1 (en) * 2009-05-25 2011-10-18 보령제약 주식회사 Composition for injection comprising docetaxel and the preparation thereof
US8476310B2 (en) 2009-10-19 2013-07-02 Scidose Llc Docetaxel formulations with lipoic acid
US8912228B2 (en) 2009-10-19 2014-12-16 Scidose Llc Docetaxel formulations with lipoic acid
US7772274B1 (en) 2009-10-19 2010-08-10 Scidose, Llc Docetaxel formulations with lipoic acid
ES2652509T3 (en) 2010-05-03 2018-02-02 Teikoku Pharma Usa, Inc. Non-aqueous taxane proemulsion formulations and methods for preparing and using them
JP6076744B2 (en) * 2013-01-04 2017-02-08 ナガセ医薬品株式会社 Pharmaceutical composition containing docetaxel
CN111557934A (en) * 2020-06-10 2020-08-21 四川汇宇制药股份有限公司 Pharmaceutical composition containing docetaxel, preparation method and application thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5403858A (en) * 1991-07-08 1995-04-04 Rhone-Poulenc Rorer, S.A. New compositions containing taxane derivatives
US5750561A (en) * 1991-07-08 1998-05-12 Rhone-Poulenc Rorer, S.A. Compositions containing taxane derivatives
US5977163A (en) * 1996-03-12 1999-11-02 Pg-Txl Company, L. P. Water soluble paclitaxel prodrugs

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5403858A (en) * 1991-07-08 1995-04-04 Rhone-Poulenc Rorer, S.A. New compositions containing taxane derivatives
US5750561A (en) * 1991-07-08 1998-05-12 Rhone-Poulenc Rorer, S.A. Compositions containing taxane derivatives
US5977163A (en) * 1996-03-12 1999-11-02 Pg-Txl Company, L. P. Water soluble paclitaxel prodrugs

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8940786B2 (en) 2012-10-01 2015-01-27 Teikoku Pharma Usa, Inc. Non-aqueous taxane nanodispersion formulations and methods of using the same
US9308195B2 (en) 2012-10-01 2016-04-12 Teikoku Pharma Usa, Inc. Non-aqueous taxane formulations and methods of using the same

Also Published As

Publication number Publication date
WO2008026048A2 (en) 2008-03-06

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