WO2008019086A3 - Detection of explosives, toxins and other compositions - Google Patents
Detection of explosives, toxins and other compositions Download PDFInfo
- Publication number
- WO2008019086A3 WO2008019086A3 PCT/US2007/017380 US2007017380W WO2008019086A3 WO 2008019086 A3 WO2008019086 A3 WO 2008019086A3 US 2007017380 W US2007017380 W US 2007017380W WO 2008019086 A3 WO2008019086 A3 WO 2008019086A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- present
- polymer
- analyte
- explosives
- toxins
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/0004—Gaseous mixtures, e.g. polluted air
- G01N33/0009—General constructional details of gas analysers, e.g. portable test equipment
- G01N33/0027—General constructional details of gas analysers, e.g. portable test equipment concerning the detector
- G01N33/0036—Specially adapted to detect a particular component
- G01N33/0057—Specially adapted to detect a particular component for warfare agents or explosives
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6432—Quenching
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/17—Nitrogen containing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/17—Nitrogen containing
- Y10T436/173076—Nitrite or nitrate
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/17—Nitrogen containing
- Y10T436/173845—Amine and quaternary ammonium
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/17—Nitrogen containing
- Y10T436/173845—Amine and quaternary ammonium
- Y10T436/174614—Tertiary amine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/17—Nitrogen containing
- Y10T436/173845—Amine and quaternary ammonium
- Y10T436/175383—Ammonia
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Combustion & Propulsion (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
The present invention generally relates to methods for modulating the optical properties of a luminescent polymer via interaction with a species (e.g., an analyte). In some cases, the present invention provides methods for determination of an analyte by monitoring a change in an optical signal of a luminescent polymer upon exposure to an analyte. Methods of the present invention may be useful for the vapor phase detection of analytes such as explosives and toxins. The present invention also provides methods for increasing the luminescence intensity of a polymer, such as a polymer that has been photobleached, by exposing the luminescent polymer to a species such as a reducing agent.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/308,298 US8158437B2 (en) | 2006-08-04 | 2007-08-02 | Luminescent detection of hydrazine and hydrazine derivatives |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83582806P | 2006-08-04 | 2006-08-04 | |
US60/835,828 | 2006-08-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008019086A2 WO2008019086A2 (en) | 2008-02-14 |
WO2008019086A3 true WO2008019086A3 (en) | 2008-05-29 |
Family
ID=38787004
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2007/017380 WO2008019086A2 (en) | 2006-08-04 | 2007-08-02 | Detection of explosives, toxins and other compositions |
Country Status (2)
Country | Link |
---|---|
US (1) | US8158437B2 (en) |
WO (1) | WO2008019086A2 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE261483T1 (en) | 1998-05-05 | 2004-03-15 | Massachusetts Inst Technology | LIGHT EMITTING POLYMERS AND DEVICES CONTAINING SAME |
US20050147534A1 (en) | 1998-05-05 | 2005-07-07 | Massachusetts Institute Of Technology | Emissive sensors and devices incorporating these sensors |
WO2006034081A2 (en) | 2004-09-17 | 2006-03-30 | Massachusetts Institute Of Technology | Polymers for analyte detection |
US8283423B2 (en) | 2006-09-29 | 2012-10-09 | Massachusetts Institute Of Technology | Polymer synthetic technique |
US8802447B2 (en) | 2006-10-05 | 2014-08-12 | Massachusetts Institute Of Technology | Emissive compositions with internal standard and related techniques |
US20090215189A1 (en) | 2006-10-27 | 2009-08-27 | Massachusetts Institute Of Technology | Sensor of species including toxins and chemical warfare agents |
US8435797B2 (en) * | 2010-12-07 | 2013-05-07 | The United States Of America As Represented By The Secretary Of The Army | Electroluminescent diode sensor |
CN103502817B (en) * | 2011-03-28 | 2016-01-20 | 前视红外系统股份有限公司 | Comprise the detection method of the analysis thing of medicine |
US8765483B2 (en) * | 2011-04-01 | 2014-07-01 | University Of Connecticut | Explosives detection substrate and methods of using the same |
EP2929325B1 (en) * | 2012-12-04 | 2020-06-24 | The University of Queensland | Method for the detection of analytes via luminescence quenching |
CN105418560B (en) * | 2015-11-09 | 2017-11-07 | 晋江尚京富本环保科技有限公司 | Long wavelength's hydrazine colorimetric fluorescence probe and preparation method thereof |
CN109385751B (en) * | 2018-09-30 | 2021-08-03 | 武汉大学 | Preparation method and application of fluorescent nanofiber membrane based on bimetallic organic framework |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5157261A (en) * | 1990-08-08 | 1992-10-20 | Eg&G Idaho, Inc. | Detection device for high explosives |
US20050226775A1 (en) * | 2000-10-17 | 2005-10-13 | Aker Craig A | Vapor sensing instrument for ultra trace chemical detection |
US20060120917A1 (en) * | 1998-05-05 | 2006-06-08 | Swager Timothy M | Emissive polymers and devices incorporating these polymers |
Family Cites Families (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US559787A (en) * | 1896-05-05 | patten | ||
US4356429A (en) * | 1980-07-17 | 1982-10-26 | Eastman Kodak Company | Organic electroluminescent cell |
US4687732A (en) * | 1983-06-10 | 1987-08-18 | Yale University | Visualization polymers and their application to diagnostic medicine |
US4513078A (en) * | 1983-10-13 | 1985-04-23 | General Electric Company | Film-based dual energy radiography |
US4992302A (en) * | 1985-10-10 | 1991-02-12 | Quantex Corporation | Process for making photoluminescent materials |
WO1989000593A1 (en) | 1987-07-16 | 1989-01-26 | Memtec Limited | Porous membranes of interpenetrating polymer networks |
US4927768A (en) * | 1988-06-29 | 1990-05-22 | Uop | Grown crystalline sensor and method for sensing |
US4946890A (en) * | 1988-08-11 | 1990-08-07 | The United States Of America As Represented By The Administrator, National Aeronautics And Space Administration | Novel ladder polymers for use as high temperature stable resins or coatings |
US5252743A (en) * | 1989-11-13 | 1993-10-12 | Affymax Technologies N.V. | Spatially-addressable immobilization of anti-ligands on surfaces |
EP0429907B1 (en) * | 1989-11-21 | 1994-06-01 | Bayer Ag | Optical biosensor |
FI91573C (en) | 1990-01-04 | 1994-07-11 | Neste Oy | Method for manufacturing electronic and electro-optical components and circuits |
US5723218A (en) * | 1990-04-16 | 1998-03-03 | Molecular Probes, Inc. | Dipyrrometheneboron difluoride labeled flourescent microparticles |
US5244813A (en) * | 1991-01-25 | 1993-09-14 | Trustees Of Tufts College | Fiber optic sensor, apparatus, and methods for detecting an organic analyte in a fluid or vapor sample |
US5254633A (en) * | 1991-07-10 | 1993-10-19 | Allied Signal Inc. | Process for the preparation of conductive polymer blends |
US5869592A (en) * | 1991-08-19 | 1999-02-09 | Maxdem Incorporated | Macromonomers having reactive side groups |
US5155149A (en) * | 1991-10-10 | 1992-10-13 | Boc Health Care, Inc. | Silicone polyurethane copolymers containing oxygen sensitive phosphorescent dye compounds |
DE69233391D1 (en) * | 1991-11-07 | 2004-09-02 | Nanotronics Inc | Hybridization of polynucleotides conjugated with chromophores and fluorophores to create a donor-donor energy transfer system |
ATE192487T1 (en) * | 1992-02-13 | 2000-05-15 | Surmodics Inc | IMMOBILIZATION OF A CHEMICAL SPECIES IN A NETWORKED MATRIX |
US5607864A (en) * | 1992-04-07 | 1997-03-04 | Societe Prolabo | Fluorescent latices having very low detection thresholds for fluorescent emission |
US5236808A (en) * | 1992-04-13 | 1993-08-17 | E. I. Du Pont De Nemours And Company | Visible photosensitizers for photopolymerizable compositions |
US5580527A (en) * | 1992-05-18 | 1996-12-03 | Moltech Corporation | Polymeric luminophores for sensing of oxygen |
EP0581058A1 (en) | 1992-07-08 | 1994-02-02 | Hoechst Aktiengesellschaft | Polyaryl ether films |
ES2113547T3 (en) * | 1992-07-31 | 1998-05-01 | Behringwerke Ag | PHOTOACTIVABLE CHEMIOLUMINISCENT MATRICES. |
DE9215344U1 (en) * | 1992-11-11 | 1994-03-24 | Faber Castell A W | Solid mine |
US5414069A (en) * | 1993-02-01 | 1995-05-09 | Polaroid Corporation | Electroluminescent polymers, processes for their use, and electroluminescent devices containing these polymers |
BE1007071A3 (en) * | 1993-04-28 | 1995-03-07 | Philips Electronics Nv | Optical systems. |
JP3198365B2 (en) | 1993-05-14 | 2001-08-13 | 隆一 山本 | Linear poly (phenylene-ethynylene-biphenylene-ethynylene) polymer |
US5364797A (en) | 1993-05-20 | 1994-11-15 | Mobil Oil Corp. | Sensor device containing mesoporous crystalline material |
US5407001A (en) * | 1993-07-08 | 1995-04-18 | Precision Castparts Corporation | Yttria-zirconia slurries and mold facecoats for casting reactive metals |
JP3534445B2 (en) * | 1993-09-09 | 2004-06-07 | 隆一 山本 | EL device using polythiophene |
US5556706A (en) * | 1993-10-06 | 1996-09-17 | Matsushita Electric Industrial Co., Ltd. | Conductive layered product and method of manufacturing the same |
US5597890A (en) * | 1993-11-01 | 1997-01-28 | Research Corporation Technologies, Inc. | Conjugated polymer exciplexes and applications thereof |
US5700696A (en) * | 1993-11-08 | 1997-12-23 | Lucent Technologies Inc. | Method for preparation of conjugated arylene or heteroarylene vinylene polymer and device including same |
US5925517A (en) * | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
US5591578A (en) * | 1993-12-10 | 1997-01-07 | California Institute Of Technology | Nucleic acid mediated electron transfer |
WO1995016681A1 (en) | 1993-12-14 | 1995-06-22 | The Trustees Of The University Of Pennsylvania | Derivatized polythiophenes and devices comprising same |
US5511547A (en) * | 1994-02-16 | 1996-04-30 | Biomedical Sensors, Ltd. | Solid state sensors |
FI95574C (en) * | 1994-02-16 | 1996-02-26 | Valtion Teknillinen | Electron-conducting molecular preparations |
US5679773A (en) * | 1995-01-17 | 1997-10-21 | Affymax Technologies N.V | Reagants and methods for immobilized polymer synthesis and display |
DE4424817A1 (en) * | 1994-07-14 | 1996-01-18 | Basf Ag | Cross-linked polymer particles with fluorescent dye |
US5512490A (en) * | 1994-08-11 | 1996-04-30 | Trustees Of Tufts College | Optical sensor, optical sensing apparatus, and methods for detecting an analyte of interest using spectral recognition patterns |
US5506420A (en) * | 1994-09-14 | 1996-04-09 | The Regents Of The University Of California | Semiconductor bio-electronic devices incorporating biochemical stabilization layers |
US5629353A (en) * | 1995-05-22 | 1997-05-13 | The Regents Of The University Of California | Highly cross-linked nanoporous polymers |
US5567622A (en) * | 1995-07-05 | 1996-10-22 | The Aerospace Corporation | Sensor for detection of nitrogen dioxide and nitrogen tetroxide |
US6623870B1 (en) * | 1996-08-02 | 2003-09-23 | The Ohio State University | Electroluminescence in light emitting polymers featuring deaggregated polymers |
US6020426A (en) * | 1996-11-01 | 2000-02-01 | Fuji Xerox Co., Ltd. | Charge-transporting copolymer, method of forming charge-transporting copolymer, electrophotographic photosensitive body, and electrophotographic device |
US6328932B1 (en) * | 1997-05-08 | 2001-12-11 | Eltron Research, Inc. | Devices and methods for the detection of basic gases |
DE19744792A1 (en) | 1997-10-10 | 1999-04-15 | Hoechst Ag | Triptycene derivatives for use in electroluminescent devices |
DE19806037A1 (en) | 1998-02-13 | 1999-08-19 | Aventis Res & Tech Gmbh & Co | Electroluminescent polymers and copolymers of triptycene structure |
US6259277B1 (en) * | 1998-07-27 | 2001-07-10 | University Of South Carolina | Use of molecular electrostatic potential to process electronic signals |
DE69841627D1 (en) | 1998-12-15 | 2010-06-02 | Max Planck Inst Fuer Polymerfo | Functional material-containing polyimide layer, device using it, and method of making this device |
WO2000066790A1 (en) * | 1999-05-05 | 2000-11-09 | The Regents Of The University Of California | Method for detecting biological agents |
US6713298B2 (en) * | 2000-01-31 | 2004-03-30 | Board Of Regents, The University Of Texas System | Method and apparatus for the delivery of samples to a chemical sensor array |
EP1263887A1 (en) | 2000-02-04 | 2002-12-11 | Massachusetts Institute Of Technology | Insulated nanoscopic pathways, compositions and devices of the same |
JP2003532878A (en) * | 2000-05-08 | 2003-11-05 | キューティエル・バイオシステムズ・リミテッド・ライアビリティ・カンパニー | Improvement of fluorescent polymer-QTL approach for biosensing |
JP2004506791A (en) | 2000-08-21 | 2004-03-04 | マサチューセッツ・インスティチュート・オブ・テクノロジー | Polymer with high internal free volume |
US20020177136A1 (en) * | 2000-08-23 | 2002-11-28 | Mcbranch Duncan W. | Peptide nucleic acid based molecular sensors for nucleic acids |
GB0021440D0 (en) * | 2000-08-31 | 2000-11-01 | Cit Alcatel | An optical signal processor |
EP1425581A4 (en) * | 2001-08-23 | 2005-03-09 | Qtl Biosystems Llc | Bio-sensing platforms for detection and quantitation of biological molecules |
US7462325B2 (en) | 2001-11-30 | 2008-12-09 | Nomadics, Inc. | Luminescent polymer particles |
AU2003295485A1 (en) * | 2002-11-14 | 2004-06-15 | Qtl Biosystems, Llc | Methods of biosensing using fluorescent polymers and quencher-tether-ligand bioconjugates |
US20040121337A1 (en) * | 2002-12-19 | 2004-06-24 | Nomadics, Inc. | Luminescent polymers and methods of use thereof |
US7291503B2 (en) * | 2003-05-21 | 2007-11-06 | Massachusetts Institute Of Technology | Reversible resistivity-based sensors |
US20050014160A1 (en) * | 2003-07-18 | 2005-01-20 | Sriram Kumaraswamy | Assays for protease enzyme activity |
JP4492847B2 (en) * | 2003-12-25 | 2010-06-30 | 株式会社ニデック | Eye refractive power measuring device |
US7417146B2 (en) * | 2004-12-17 | 2008-08-26 | Eastman Kodak Company | Facial tris-cyclometallated group 9 complex synthesis |
-
2007
- 2007-08-02 WO PCT/US2007/017380 patent/WO2008019086A2/en active Application Filing
- 2007-08-02 US US12/308,298 patent/US8158437B2/en not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5157261A (en) * | 1990-08-08 | 1992-10-20 | Eg&G Idaho, Inc. | Detection device for high explosives |
US20060120917A1 (en) * | 1998-05-05 | 2006-06-08 | Swager Timothy M | Emissive polymers and devices incorporating these polymers |
US20050226775A1 (en) * | 2000-10-17 | 2005-10-13 | Aker Craig A | Vapor sensing instrument for ultra trace chemical detection |
Non-Patent Citations (2)
Title |
---|
THOMAS SAMUEL W 3RD ET AL: "Amplifying fluorescent polymer sensors for the explosives taggant 2,3-dimethyl-2,3-dinitrobutane (DMNB).", CHEMICAL COMMUNICATIONS (CAMBRIDGE, ENGLAND) 28 SEP 2005, no. 36, 28 September 2005 (2005-09-28), pages 4572 - 4574, XP002462280, ISSN: 1359-7345 * |
THOMAS, S.; SWAGER, T.: "Designing Amplifying Polymer Sensors for Explosives and Toxic Chemicals", POLYMERIC MATERIALS: SCIENCE AND ENGINEERING, vol. 95, September 2006 (2006-09-01), pages 81 - 82, XP009093648 * |
Also Published As
Publication number | Publication date |
---|---|
US8158437B2 (en) | 2012-04-17 |
US20100112715A1 (en) | 2010-05-06 |
WO2008019086A2 (en) | 2008-02-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2008019086A3 (en) | Detection of explosives, toxins and other compositions | |
WO2008045307A3 (en) | Emissive compositions with internal standard and related techniques | |
WO2007098184A3 (en) | Methods and compositions for analyte detection | |
WO2007098279A3 (en) | Analyte detection using barcoded polymers | |
WO2007120265A3 (en) | Coded molecules for detecting target analytes | |
WO2007002264A3 (en) | Biomarker for ovarian cancer: ctap3-related proteins | |
WO2010132453A3 (en) | Methods and compositions for analyte detection | |
WO2007113590A3 (en) | Fluorescent assay | |
WO2008020823A3 (en) | Cooperative reporter systems, components, and methods for analyte detection | |
WO2006118835A3 (en) | Topical composition fluorescence detection | |
WO2006099126A3 (en) | Biomarkers for ovarian cancer and endometrial cancer: hepcidin | |
WO2008105896A3 (en) | Analyte determination utilizing mass tagging reagents comprising a non-encoded detectable label | |
EP1845363A3 (en) | Sample analyzer | |
WO2008106648A3 (en) | Immunoassays exhibiting a reduction in prozone phenomena | |
WO2008130376A3 (en) | Determination of explosives including rdx | |
WO2007087534A3 (en) | Methods, mixtures, kits and compositions pertaining to analyte determination | |
WO2009075306A1 (en) | Luminescence measurement method and luminescence measurement system | |
WO2007056250A3 (en) | Heterogeneous assay of analytes in solution using polymers | |
WO2009063840A1 (en) | Method and kit for measurement of endotoxin level | |
WO2007002527A3 (en) | BIOMARKERS FOR OVARIAN CANCER: β-2 MICROGLOBULIN | |
WO2008136805A3 (en) | Sensor of species including toxins and chemical warfare agents | |
WO2009007846A3 (en) | Methods for modifying, isolating, detecting, visualizing, and quantifying citrullinated and/or homocitrullinated peptides, polypeptides and proteins | |
WO2007050581A3 (en) | An albumin-based colloid composition having at least one protected thiol region, methods of making, and methods of use | |
WO2019113075A3 (en) | Microbial-based biosensors | |
DK2118666T3 (en) | Method of normalizing the concentration of analytes in a urine sample |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 07811076 Country of ref document: EP Kind code of ref document: A2 |
|
DPE1 | Request for preliminary examination filed after expiration of 19th month from priority date (pct application filed from 20040101) | ||
NENP | Non-entry into the national phase |
Ref country code: DE |
|
NENP | Non-entry into the national phase |
Ref country code: RU |
|
122 | Ep: pct application non-entry in european phase |
Ref document number: 07811076 Country of ref document: EP Kind code of ref document: A2 |
|
WWE | Wipo information: entry into national phase |
Ref document number: 12308298 Country of ref document: US |