WO2008006117A3 - Methods for preventing, postponing or improving the outcome of spinal device and fusion procedures - Google Patents

Methods for preventing, postponing or improving the outcome of spinal device and fusion procedures Download PDF

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Publication number
WO2008006117A3
WO2008006117A3 PCT/US2007/073089 US2007073089W WO2008006117A3 WO 2008006117 A3 WO2008006117 A3 WO 2008006117A3 US 2007073089 W US2007073089 W US 2007073089W WO 2008006117 A3 WO2008006117 A3 WO 2008006117A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
outcome
improving
preventing
postponing
Prior art date
Application number
PCT/US2007/073089
Other languages
French (fr)
Other versions
WO2008006117A2 (en
Inventor
James R Gorman
Original Assignee
Bioassets Dev Corp
James R Gorman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioassets Dev Corp, James R Gorman filed Critical Bioassets Dev Corp
Priority to US12/307,902 priority Critical patent/US20100093829A1/en
Priority to CA 2692430 priority patent/CA2692430A1/en
Publication of WO2008006117A2 publication Critical patent/WO2008006117A2/en
Publication of WO2008006117A3 publication Critical patent/WO2008006117A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Abstract

Methods for identifying subjects who could benefit therapeutically from administration of a high specificity cytokine inhibitor are provided. Subjects that are identified include those that are eligible, based on pre-determined criteria, for a spinal device or fusion procedure, such as the implantation of a nucleus replacement device, an annular repair device, or a fusion device. Methods of preventing such procedures or improving the outcome of such procedures are also provided, and include administering a TAT to the subject by any route or regimen of administration, including the regimens described herein.
PCT/US2007/073089 2006-07-07 2007-07-09 Methods for preventing, postponing or improving the outcome of spinal device and fusion procedures WO2008006117A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US12/307,902 US20100093829A1 (en) 2006-07-07 2007-07-09 Methods for preventing, postponing or improving the outcome of spinal device and fusion procedures
CA 2692430 CA2692430A1 (en) 2006-07-07 2007-07-09 Methods for preventing, postponing or improving the outcome of spinal device and fusion procedures

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US81955506P 2006-07-07 2006-07-07
US60/819,555 2006-07-07
US84749306P 2006-09-27 2006-09-27
US60/847,493 2006-09-27

Publications (2)

Publication Number Publication Date
WO2008006117A2 WO2008006117A2 (en) 2008-01-10
WO2008006117A3 true WO2008006117A3 (en) 2008-11-20

Family

ID=38895521

Family Applications (3)

Application Number Title Priority Date Filing Date
PCT/US2007/073092 WO2008006118A2 (en) 2006-07-07 2007-07-09 Novel regimens for treating diseases and disorders
PCT/US2007/073067 WO2008006106A2 (en) 2006-07-07 2007-07-09 Methods for preventing, postponing or improving the outcome of invasive spinal procedures
PCT/US2007/073089 WO2008006117A2 (en) 2006-07-07 2007-07-09 Methods for preventing, postponing or improving the outcome of spinal device and fusion procedures

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PCT/US2007/073092 WO2008006118A2 (en) 2006-07-07 2007-07-09 Novel regimens for treating diseases and disorders
PCT/US2007/073067 WO2008006106A2 (en) 2006-07-07 2007-07-09 Methods for preventing, postponing or improving the outcome of invasive spinal procedures

Country Status (3)

Country Link
US (6) US20080019975A1 (en)
CA (3) CA2692428A1 (en)
WO (3) WO2008006118A2 (en)

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