WO2008005960A3 - Prion processing - Google Patents

Prion processing Download PDF

Info

Publication number
WO2008005960A3
WO2008005960A3 PCT/US2007/072702 US2007072702W WO2008005960A3 WO 2008005960 A3 WO2008005960 A3 WO 2008005960A3 US 2007072702 W US2007072702 W US 2007072702W WO 2008005960 A3 WO2008005960 A3 WO 2008005960A3
Authority
WO
WIPO (PCT)
Prior art keywords
pathogenic
prion
prions
porous medium
fluid
Prior art date
Application number
PCT/US2007/072702
Other languages
French (fr)
Other versions
WO2008005960A2 (en
Inventor
Roberto Rodriguez
Samuel O Sowemimo-Coker
Mikhail Fomovsky
Original Assignee
Pall Corp
Roberto Rodriguez
Samuel O Sowemimo-Coker
Mikhail Fomovsky
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pall Corp, Roberto Rodriguez, Samuel O Sowemimo-Coker, Mikhail Fomovsky filed Critical Pall Corp
Publication of WO2008005960A2 publication Critical patent/WO2008005960A2/en
Publication of WO2008005960A3 publication Critical patent/WO2008005960A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
    • A61M1/3633—Blood component filters, e.g. leukocyte filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/20—Pathogenic agents

Abstract

A method for processing prions is disclosed, comprising contacting at least one porous medium with a pathogenic prion-containing fluid such that pathogenic prions are retained and/or captured by the porous medium; contacting the porous medium with another fluid such that pathogenic prions are released from the porous medium to provide a first released pathogenic prion-containing fluid; placing a fluid containing the released pathogenic prions in a first spin device including a separation medium; and, centrifuging the spin device to provide a first concentrated pathogenic prion-containing retentate.
PCT/US2007/072702 2006-07-07 2007-07-03 Prion processing WO2008005960A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81895806P 2006-07-07 2006-07-07
US60/818,958 2006-07-07

Publications (2)

Publication Number Publication Date
WO2008005960A2 WO2008005960A2 (en) 2008-01-10
WO2008005960A3 true WO2008005960A3 (en) 2008-03-06

Family

ID=38577439

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/072702 WO2008005960A2 (en) 2006-07-07 2007-07-03 Prion processing

Country Status (1)

Country Link
WO (1) WO2008005960A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013152253A1 (en) * 2012-04-05 2013-10-10 Terumo Bct, Inc. Syestem and method for collecting and treating plasma protein fractions
US9421317B2 (en) 2012-06-08 2016-08-23 Pall Corporation Cell harvesting device and system
US9427512B2 (en) 2012-06-08 2016-08-30 Pall Corporation Filter device

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4340479A (en) * 1978-05-15 1982-07-20 Pall Corporation Process for preparing hydrophilic polyamide membrane filter media and product
US4880548A (en) * 1988-02-17 1989-11-14 Pall Corporation Device and method for separating leucocytes from platelet concentrate
US4925572A (en) * 1987-10-20 1990-05-15 Pall Corporation Device and method for depletion of the leukocyte content of blood and blood components
US5690815A (en) * 1992-07-13 1997-11-25 Pall Corporation Automated system for processing biological fluid
US5833860A (en) * 1995-08-28 1998-11-10 Millipore Investment Holdings Limited Centrifugal adsorptive sample preparation device and method
US6074869A (en) * 1994-07-28 2000-06-13 Pall Corporation Fibrous web for processing a fluid
WO2002096563A2 (en) * 2001-05-31 2002-12-05 Pall Corporation Well for processing and filtering a fluid
WO2004050851A2 (en) * 2002-12-03 2004-06-17 The American National Red Cross Prion protein ligands and methods of use

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4340479A (en) * 1978-05-15 1982-07-20 Pall Corporation Process for preparing hydrophilic polyamide membrane filter media and product
US4340479B1 (en) * 1978-05-15 1996-08-27 Pall Corp Process for preparing hydrophilic polyamide membrane filter media and product
US4925572A (en) * 1987-10-20 1990-05-15 Pall Corporation Device and method for depletion of the leukocyte content of blood and blood components
US4880548A (en) * 1988-02-17 1989-11-14 Pall Corporation Device and method for separating leucocytes from platelet concentrate
US5690815A (en) * 1992-07-13 1997-11-25 Pall Corporation Automated system for processing biological fluid
US6074869A (en) * 1994-07-28 2000-06-13 Pall Corporation Fibrous web for processing a fluid
US5833860A (en) * 1995-08-28 1998-11-10 Millipore Investment Holdings Limited Centrifugal adsorptive sample preparation device and method
WO2002096563A2 (en) * 2001-05-31 2002-12-05 Pall Corporation Well for processing and filtering a fluid
WO2004050851A2 (en) * 2002-12-03 2004-06-17 The American National Red Cross Prion protein ligands and methods of use

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
BURNOUF ET AL: "Current strategies to prevent transmission of prions by human plasma derivatives", TRANSFUSION CLINIQUE ET BIOLOGIQUE, ARNETTE-BLACKWELL, PARIS, FR, vol. 13, no. 5, 1 February 2007 (2007-02-01), pages 320 - 328, XP005869901, ISSN: 1246-7820 *
CERVIA ET AL: "An Overview of Prion Biology and the Role of Blood Filtration in Reducing the Risk of Transfusion-Transmitted Variant Creutzfeldt-Jakob Disease", TRANSFUSION MEDICINE REVIEWS, GRUNE AND STRATTON, ORLANDO, FL,, US, vol. 20, no. 3, July 2006 (2006-07-01), pages 190 - 206, XP005505464, ISSN: 0887-7963 *
GREGORI ET AL: "Reduction in infectivity of endogenous transmissible spongiform encephalopathies present in blood by adsorption to selective affinity resins", LANCET THE, LANCET LIMITED. LONDON, GB, vol. 368, no. 9554, 22 December 2006 (2006-12-22), pages 2226 - 2230, XP005812860, ISSN: 0140-6736 *
GREGORI L ET AL: "Effectiveness of leucoreduction for removal of infectivity of transmissible spongiform encephalopathies from blood", LANCET THE, LANCET LIMITED. LONDON, GB, vol. 364, no. 9433, 7 August 2004 (2004-08-07), pages 529 - 531, XP004738181, ISSN: 0140-6736 *
GREGORI LUISA ET AL: "Reduction of transmissible spongiform encephalopathy infectivity from human red blood cells with prion protein affinity ligands.", TRANSFUSION JUL 2006, vol. 46, no. 7, July 2006 (2006-07-01), pages 1152 - 1161, XP002455751, ISSN: 0041-1132 *
ORTOLANO GIROLAMO A ET AL: "Prion biology in transfusion medicine: implications for lab testing.", MLO: MEDICAL LABORATORY OBSERVER SEP 2005, vol. 37, no. 9, September 2005 (2005-09-01), pages 10 , 12 , 14 passim; quiz 24 - 25, XP009091194, ISSN: 0580-7247 *
SOWEMIMO-COKER S O ET AL: "Pall leukotrap affinity prion-reduction filter removes exogenous infectious prions and endogenous infectivity from red cell concentrates.", VOX SANGUINIS MAY 2006, vol. 90, no. 4, May 2006 (2006-05-01), pages 265 - 275, XP002455599, ISSN: 0042-9007 *
SOWEMIMO-COKER SAMUEL ET AL: "Removal of exogenous (spiked) and endogenous prion infectivity from red cells with a new prototype of leukoreduction filter.", TRANSFUSION DEC 2005, vol. 45, no. 12, December 2005 (2005-12-01), pages 1839 - 1844, XP002455600, ISSN: 0041-1132 *
TURNER ET AL: "Prion reduction filters", LANCET THE, LANCET LIMITED. LONDON, GB, vol. 368, no. 9554, 23 December 2006 (2006-12-23), pages 2190 - 2191, XP005812834, ISSN: 0140-6736 *

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Publication number Publication date
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