WO2008005315A8 - Automatic injection device - Google Patents

Automatic injection device Download PDF

Info

Publication number
WO2008005315A8
WO2008005315A8 PCT/US2007/015095 US2007015095W WO2008005315A8 WO 2008005315 A8 WO2008005315 A8 WO 2008005315A8 US 2007015095 W US2007015095 W US 2007015095W WO 2008005315 A8 WO2008005315 A8 WO 2008005315A8
Authority
WO
WIPO (PCT)
Prior art keywords
injection device
automatic injection
syringe
kits
housing
Prior art date
Application number
PCT/US2007/015095
Other languages
French (fr)
Other versions
WO2008005315A3 (en
WO2008005315A2 (en
WO2008005315A9 (en
Inventor
Joseph F Julian
Steven Rolfe
Stephen Bicknell
Jeremy Marshall
Original Assignee
Abbott Biotech Ltd
Joseph F Julian
Steven Rolfe
Stephen Bicknell
Jeremy Marshall
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AU2007269791A priority Critical patent/AU2007269791B2/en
Priority to KR1020087032140A priority patent/KR101396797B1/en
Application filed by Abbott Biotech Ltd, Joseph F Julian, Steven Rolfe, Stephen Bicknell, Jeremy Marshall filed Critical Abbott Biotech Ltd
Priority to NZ572765A priority patent/NZ572765A/en
Priority to KR1020127017120A priority patent/KR101440795B1/en
Priority to MX2008016335A priority patent/MX2008016335A/en
Priority to BRPI0713802-4A priority patent/BRPI0713802A2/en
Priority to EP07810031.0A priority patent/EP2043711A4/en
Priority to CA002651992A priority patent/CA2651992A1/en
Priority to JP2009518284A priority patent/JP5535623B2/en
Priority to CN200780024818.5A priority patent/CN101484199B/en
Publication of WO2008005315A2 publication Critical patent/WO2008005315A2/en
Publication of WO2008005315A9 publication Critical patent/WO2008005315A9/en
Priority to IL195235A priority patent/IL195235A/en
Publication of WO2008005315A3 publication Critical patent/WO2008005315A3/en
Priority to ZA2008/10349A priority patent/ZA200810349B/en
Publication of WO2008005315A8 publication Critical patent/WO2008005315A8/en
Priority to IL215312A priority patent/IL215312A/en
Priority to IL221300A priority patent/IL221300A/en
Priority to IL221301A priority patent/IL221301A/en
Priority to IL244058A priority patent/IL244058A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps
    • A61M5/3204—Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
    • G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
    • G09B23/28—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
    • G09B23/285—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine for injections, endoscopy, bronchoscopy, sigmoidscopy, insertion of contraceptive devices or enemas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006—Having specific accessories
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2026—Semi-automatic, e.g. user activated piston is assisted by additional source of energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/206—With automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3125—Details specific display means, e.g. to indicate dose setting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A61M2005/31508—Means for blocking or restricting the movement of the rod or piston provided on the piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00—Ancillary equipment
    • A61M2209/02—Equipment for testing the apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

The invention provides an automatic injection device for providing a subcutaneous injection of a substance into a user, comprising a housing; a syringe movably disposed in the housing, the syringe including a barrel portion for holding the substance; a hollow needle; a bung; a plunger for moving the syringe such that the needle projects from the housing and for subsequently applying pressure to the bung; a compressible expanded central portion; a flange; and a biasing mechanism. The present invention also provides methods and kits for using an automatic injection device, and methods and kits for promoting an automatic injection device comprising a medication based on advantageous properties of the device as compared to a pre-filled syringe. The invention also provides methods and kits for training a recipient on use of the automatic injection device.
PCT/US2007/015095 2006-06-30 2007-06-29 Automatic injection device WO2008005315A2 (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
KR1020127017120A KR101440795B1 (en) 2006-06-30 2007-06-29 Automatic injection device
CN200780024818.5A CN101484199B (en) 2006-06-30 2007-06-29 Automatic injection device
NZ572765A NZ572765A (en) 2006-06-30 2007-06-29 Automatic injection device with rod driving syringe longitudinally split with radially compressible pair of wings along its length
KR1020087032140A KR101396797B1 (en) 2006-06-30 2007-06-29 Automatic injection device
MX2008016335A MX2008016335A (en) 2006-06-30 2007-06-29 Automatic injection device.
BRPI0713802-4A BRPI0713802A2 (en) 2006-06-30 2007-06-29 automatic injection device
EP07810031.0A EP2043711A4 (en) 2006-06-30 2007-06-29 Automatic injection device
CA002651992A CA2651992A1 (en) 2006-06-30 2007-06-29 Automatic injection device
JP2009518284A JP5535623B2 (en) 2006-06-30 2007-06-29 Automatic injection device
AU2007269791A AU2007269791B2 (en) 2006-06-30 2007-06-29 Automatic injection device
IL195235A IL195235A (en) 2006-06-30 2008-11-11 Automatic injection device
ZA2008/10349A ZA200810349B (en) 2006-06-30 2008-12-05 Automatic injection device
IL215312A IL215312A (en) 2006-06-30 2011-09-22 Automatic injection device
IL221300A IL221300A (en) 2006-06-30 2012-08-05 Automatic injection device
IL221301A IL221301A (en) 2006-06-30 2012-08-05 Automatic injection device
IL244058A IL244058A0 (en) 2006-06-30 2016-02-09 Automatic injection device

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US81784906P 2006-06-30 2006-06-30
US81823106P 2006-06-30 2006-06-30
US60/817,849 2006-06-30
US60/818,231 2006-06-30
US83890506P 2006-08-18 2006-08-18
US60/838,905 2006-08-18
US84996706P 2006-10-06 2006-10-06
US60/849,967 2006-10-06
US89926207P 2007-02-02 2007-02-02
US60/899,262 2007-02-02
US90462607P 2007-03-01 2007-03-01
US60/904,626 2007-03-01
US91817407P 2007-03-14 2007-03-14
US60/918,174 2007-03-14

Publications (4)

Publication Number Publication Date
WO2008005315A2 WO2008005315A2 (en) 2008-01-10
WO2008005315A9 WO2008005315A9 (en) 2008-03-13
WO2008005315A3 WO2008005315A3 (en) 2008-11-13
WO2008005315A8 true WO2008005315A8 (en) 2009-01-15

Family

ID=38895125

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/015095 WO2008005315A2 (en) 2006-06-30 2007-06-29 Automatic injection device

Country Status (16)

Country Link
US (5) US8679061B2 (en)
EP (1) EP2043711A4 (en)
JP (6) JP5535623B2 (en)
KR (2) KR101396797B1 (en)
CN (4) CN103316403B (en)
AU (1) AU2007269791B2 (en)
BR (1) BRPI0713802A2 (en)
CA (1) CA2651992A1 (en)
IL (5) IL195235A (en)
MX (1) MX2008016335A (en)
NZ (3) NZ572765A (en)
RU (1) RU2015135983A (en)
SG (1) SG173339A1 (en)
TW (3) TWI542374B (en)
WO (1) WO2008005315A2 (en)
ZA (2) ZA200810349B (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8945063B2 (en) 2009-03-20 2015-02-03 Antares Pharma, Inc. Hazardous agent injection system
US9144648B2 (en) 2006-05-03 2015-09-29 Antares Pharma, Inc. Injector with adjustable dosing
US9180259B2 (en) 2005-01-24 2015-11-10 Antares Pharma, Inc. Prefilled syringe jet injector
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US9333309B2 (en) 2002-02-11 2016-05-10 Antares Pharma, Inc. Intradermal injector
US9364610B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Injection device with cammed ram assembly
US9393367B2 (en) 2013-03-12 2016-07-19 Antares Pharma, Inc. Prefilled syringes and kits thereof
US9446195B2 (en) 2011-07-15 2016-09-20 Antares Pharma, Inc. Injection device with cammed ram assembly
US9486583B2 (en) 2012-03-06 2016-11-08 Antares Pharma, Inc. Prefilled syringe with breakaway force feature
US9561333B2 (en) 2008-08-05 2017-02-07 Antares Pharma, Inc. Multiple dosage injector

Families Citing this family (302)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6090382A (en) 1996-02-09 2000-07-18 Basf Aktiengesellschaft Human antibodies that bind human TNFα
NZ536216A (en) * 1996-02-09 2006-08-31 Abbott Biotech Ltd Use of an isolated antibody D2E7 for the treatment of a disorder in which TNF(alpha) activity is detrimental
CA2868614A1 (en) 2001-06-08 2002-12-08 Abbott Laboratories (Bermuda) Ltd. Methods of administering anti-tnf.alpha. antibodies
US20090280065A1 (en) * 2006-04-10 2009-11-12 Willian Mary K Uses and Compositions for Treatment of Psoriasis
PT1944322E (en) * 2002-07-19 2015-07-01 Abbvie Biotechnology Ltd Treatment of tnf alpha related disorders
US20040033228A1 (en) 2002-08-16 2004-02-19 Hans-Juergen Krause Formulation of human antibodies for treating TNF-alpha associated disorders
US20090204076A1 (en) * 2003-02-03 2009-08-13 Barry Peter Liversidge Medical Injector
TWI439284B (en) 2004-04-09 2014-06-01 Abbvie Biotechnology Ltd Multiple-variable dose regimen for treating tnfα-related disorders
GB0414054D0 (en) 2004-06-23 2004-07-28 Owen Mumford Ltd Improvements relating to automatic injection devices
US10737028B2 (en) 2004-11-22 2020-08-11 Kaleo, Inc. Devices, systems and methods for medicament delivery
JP4960252B2 (en) 2004-11-22 2012-06-27 インテリジェクト，インコーポレイテッド Device, system and method for drug delivery
US7648482B2 (en) 2004-11-22 2010-01-19 Intelliject, Inc. Devices, systems, and methods for medicament delivery
US7947017B2 (en) 2004-11-22 2011-05-24 Intelliject, Inc. Devices, systems and methods for medicament delivery
US7648483B2 (en) 2004-11-22 2010-01-19 Intelliject, Inc. Devices, systems and methods for medicament delivery
US11590286B2 (en) 2004-11-22 2023-02-28 Kaleo, Inc. Devices, systems and methods for medicament delivery
US8231573B2 (en) 2005-02-01 2012-07-31 Intelliject, Inc. Medicament delivery device having an electronic circuit system
US8226610B2 (en) 2005-02-01 2012-07-24 Intelliject, Inc. Medical injector with compliance tracking and monitoring
JP4948422B2 (en) 2005-02-01 2012-06-06 インテリジェクト，インコーポレイテッド Drug delivery apparatus, system and method
US8206360B2 (en) 2005-02-01 2012-06-26 Intelliject, Inc. Devices, systems and methods for medicament delivery
US9022980B2 (en) 2005-02-01 2015-05-05 Kaleo, Inc. Medical injector simulation device
US8361026B2 (en) 2005-02-01 2013-01-29 Intelliject, Inc. Apparatus and methods for self-administration of vaccines and other medicaments
NZ627177A (en) 2005-05-16 2016-02-26 Abbvie Biotechnology Ltd Use of tnf inhibitor for treatment of erosive polyarthritis
BRPI0618085A2 (en) 2005-11-01 2011-08-16 Abbott Biotech Ltd Processes and kits for diagnosis of ankylosing spondylitis using biomarkers
US20070173770A1 (en) 2006-01-23 2007-07-26 The Medical House Plc Injection device
US10675417B2 (en) 2006-03-07 2020-06-09 Leibovici, Llc Method and apparatus for applying an anesthetic and bactericide
US10004855B2 (en) 2006-03-07 2018-06-26 Leibovici Llc Method and apparatus for applying an anesthetic and bactericide
NZ596517A (en) 2006-04-05 2013-06-28 Abbott Biotech Ltd Antibody purification
EP2007426A4 (en) 2006-04-10 2010-06-16 Abbott Biotech Ltd Uses and compositions for treatment of psoriatic arthritis
US20090317399A1 (en) * 2006-04-10 2009-12-24 Pollack Paul F Uses and compositions for treatment of CROHN'S disease
US20080118496A1 (en) * 2006-04-10 2008-05-22 Medich John R Uses and compositions for treatment of juvenile rheumatoid arthritis
US9605064B2 (en) * 2006-04-10 2017-03-28 Abbvie Biotechnology Ltd Methods and compositions for treatment of skin disorders
EP2012586A4 (en) 2006-04-10 2010-08-18 Abbott Biotech Ltd Uses and compositions for treatment of ankylosing spondylitis
US9399061B2 (en) * 2006-04-10 2016-07-26 Abbvie Biotechnology Ltd Methods for determining efficacy of TNF-α inhibitors for treatment of rheumatoid arthritis
WO2007131013A1 (en) 2006-05-03 2007-11-15 Antares Pharma, Inc. Two-stage reconstituting injector
US20100021451A1 (en) 2006-06-08 2010-01-28 Wong Robert L Uses and compositions for treatment of ankylosing spondylitis
US20080311043A1 (en) * 2006-06-08 2008-12-18 Hoffman Rebecca S Uses and compositions for treatment of psoriatic arthritis
US9259535B2 (en) 2006-06-22 2016-02-16 Excelsior Medical Corporation Antiseptic cap equipped syringe
US11229746B2 (en) 2006-06-22 2022-01-25 Excelsior Medical Corporation Antiseptic cap
US8167847B2 (en) 2006-06-22 2012-05-01 Excelsior Medical Corporation Antiseptic cap and antiseptic cap equipped plunger and syringe barrel assembly
US9700710B2 (en) 2006-06-22 2017-07-11 Excelsior Medical Corporation Antiseptic cap equipped syringe
AU2007269791B2 (en) 2006-06-30 2013-10-03 Abbvie Biotechnology Ltd Automatic injection device
CA2667655A1 (en) 2006-10-27 2008-05-15 Abbott Biotechnology Ltd. Crystalline anti-htnfalpha antibodies
RU2476442C2 (en) 2007-03-29 2013-02-27 Эббот Лэборетриз Crystalline human il-12 antibodies
EP2679996A1 (en) * 2007-05-31 2014-01-01 AbbVie Inc. Biomarkers predictive of the responsiveness to TNF-alfa inhibitors in autoimmune disorders
US8999337B2 (en) * 2007-06-11 2015-04-07 Abbvie Biotechnology Ltd. Methods for treating juvenile idiopathic arthritis by inhibition of TNFα
EP2173380A4 (en) * 2007-07-13 2011-08-31 Abbott Biotech Ltd METHODS AND COMPOSITIONS FOR PULMONARY ADMINISTRATION OF A TNFa INHIBITOR
MX2010001488A (en) 2007-08-08 2010-03-01 Abbott Lab Compositions and methods for crystallizing antibodies.
US8309088B2 (en) * 2007-08-10 2012-11-13 Regeneron Pharmaceuticals, Inc. Method of treating osteoarthritis with an antibody to NGF
EP2195052B1 (en) 2007-10-02 2019-09-04 Medimop Medical Projects Ltd. External drug pump
MX354100B (en) * 2007-11-30 2018-02-13 Abbvie Biotechnology Ltd Star Protein formulations and methods of making same.
US8883146B2 (en) 2007-11-30 2014-11-11 Abbvie Inc. Protein formulations and methods of making same
WO2009086550A1 (en) * 2008-01-03 2009-07-09 Abbott Laboratories Predicting long-term efficacy of a compound in the treatment of psoriasis
CA2711984A1 (en) 2008-01-15 2009-07-23 Abbott Gmbh & Co. Kg Powdered protein compositions and methods of making same
CN101998870B (en) 2008-02-11 2013-12-25 特克法马许可公司 Administering apparatus comprising holding device
EP2268342B1 (en) 2008-03-10 2015-09-16 Antares Pharma, Inc. Injector safety device
USD994111S1 (en) 2008-05-12 2023-08-01 Kaleo, Inc. Medicament delivery device cover
US8021344B2 (en) 2008-07-28 2011-09-20 Intelliject, Inc. Medicament delivery device configured to produce an audible output
US8177749B2 (en) * 2008-05-20 2012-05-15 Avant Medical Corp. Cassette for a hidden injection needle
US8052645B2 (en) 2008-07-23 2011-11-08 Avant Medical Corp. System and method for an injection using a syringe needle
CA3142745A1 (en) 2008-05-20 2009-11-26 Avant Medical Corp. Autoinjector system
WO2010035056A1 (en) * 2008-09-29 2010-04-01 Becton Dickinson France Automatic injection device with sensitive indicator of completed injection
EP2180459A1 (en) 2008-10-24 2010-04-28 Sanofi-Aventis Deutschland GmbH Device for simulating the operation of a medication delivery device
US9078992B2 (en) 2008-10-27 2015-07-14 Pursuit Vascular, Inc. Medical device for applying antimicrobial to proximal end of catheter
GB0901801D0 (en) * 2009-02-05 2009-03-11 Medical House Plc The Improved autoinjector
JP6078230B2 (en) 2009-03-02 2017-02-08 セブンス センス バイオシステムズ，インコーポレーテッド Techniques and devices related to blood sampling
US9295417B2 (en) 2011-04-29 2016-03-29 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
WO2010100213A1 (en) * 2009-03-05 2010-09-10 Sanofi-Aventis Deutschland Gmbh Drug delivery device
MX2011011541A (en) 2009-04-29 2012-02-28 Abbott Biotech Ltd Automatic injection device.
CN104490767A (en) * 2009-05-04 2015-04-08 艾伯维生物技术有限公司 Stable High Protein Concentration Formulations Of Human Anti-tnf-alpha-antibodies
WO2010136078A1 (en) * 2009-05-29 2010-12-02 Tecpharma Licensing Ag Injection device, especially auto-injector, comprising an anti-pricking mechanism and/or overload protection for a product container.
US8920373B2 (en) 2009-07-15 2014-12-30 Teva Pharmaceutical Industries, Ltd. Reduced volume formulation of glatiramer acetate and methods of administration
PL2275086T3 (en) * 2009-07-15 2012-09-28 Teva Pharma Reduced volume formulation of glatiramer acetate and methods of administration
SI2949335T1 (en) 2009-08-20 2017-05-31 Yeda Research & Development Company, Ltd. Low frequency glatiramer acetate therapy
WO2011039226A1 (en) 2009-09-30 2011-04-07 Sanofi-Aventis Deutschland Gmbh Method for assembling a drug delivery device, assembly for a drug delivery device and piston rod for a drug delivery device
US9265891B2 (en) * 2009-09-30 2016-02-23 Sanofi-Aventis Deutschland Gmbh Assembly of a drug delivery device
EP3023114A1 (en) * 2009-10-08 2016-05-25 SHL Group AB Medicament delivery device
CN104474604B (en) * 2009-10-13 2017-08-11 瓦莱里塔斯公司 Fluid delivery system
AU2010306625B2 (en) 2009-10-16 2015-01-22 Janssen Biotech Inc. Palm activated drug delivery device
US9233213B2 (en) 2009-10-16 2016-01-12 Janssen Biotech, Inc. Palm activated drug delivery device
EP2493537B1 (en) * 2009-10-30 2017-12-06 Seventh Sense Biosystems, Inc. Systems and methods for treating, sanitizing, and/or shielding the skin or devices applied to the skin
US8439896B2 (en) * 2009-11-13 2013-05-14 The Invention Science Fund I, Llc Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject
US9078863B2 (en) * 2009-11-13 2015-07-14 The Invention Science Fund I, Llc Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject
US8894630B2 (en) * 2009-11-13 2014-11-25 The Invention Science Fund I, Llc Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject
NZ627052A (en) 2009-12-15 2015-12-24 Abbvie Biotechnology Ltd Improved firing button for automatic injection device
USRE49251E1 (en) 2010-01-04 2022-10-18 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
WO2011094573A1 (en) 2010-01-28 2011-08-04 Seventh Sense Biosystems, Inc. Monitoring or feedback systems and methods
HUE025794T2 (en) * 2010-03-01 2016-05-30 Lilly Co Eli Automatic injection device with delay mechanism including dual functioning biasing member
IT1398501B1 (en) * 2010-03-10 2013-03-01 Menarini Int Operations Lu Sa AUTOINECTOR DEVICE FOR TWO DRUG DOSES
BR112012023895A2 (en) 2010-03-17 2016-11-29 Abbott Res Bv anti nerve growth factor (ngf) compositions
JP5809242B2 (en) 2010-04-21 2015-11-10 アッヴィ バイオテクノロジー リミテッド Wearable automatic infusion device for controlled delivery of therapeutic agents
PT2575884T (en) 2010-06-03 2018-10-31 Abbvie Biotechnology Ltd Uses and compositions for treatment of hidradenitis suppurativa (hs)
WO2011163347A2 (en) * 2010-06-23 2011-12-29 Seventh Sense Biosystems, Inc. Sampling devices and methods involving relatively little pain
US20120016308A1 (en) 2010-07-16 2012-01-19 Seventh Sense Biosystems, Inc. Low-pressure packaging for fluid devices
US20130158482A1 (en) 2010-07-26 2013-06-20 Seventh Sense Biosystems, Inc. Rapid delivery and/or receiving of fluids
WO2012021801A2 (en) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systems and techniques for monitoring subjects
US20130331786A1 (en) * 2010-10-25 2013-12-12 Sanofi-Aventis Deutschland Gmbh Device for Controlling a Penetration Depth of Injection Needle
JP6055773B2 (en) 2010-11-09 2016-12-27 セブンス センス バイオシステムズ，インコーポレーテッド System and interface for blood sampling
KR101841527B1 (en) 2010-11-11 2018-03-23 애브비 바이오테크놀로지 리미티드 IMPROVED HIGH CONCENTRATION ANTI-TNFα ANTIBODY LIQUID FORMULATIONS
GB201020472D0 (en) 2010-12-02 2011-01-19 Oval Medical Technologies Ltd A drive assembly for an autoinjector
WO2012103141A1 (en) * 2011-01-24 2012-08-02 Abbott Biotechnology Ltd. Automatic injection devices having overmolded gripping surfaces
ES2859511T3 (en) 2011-01-24 2021-10-04 Abbvie Biotechnology Ltd Removal of needle guards from syringes and automatic injection devices
AU2012210170B2 (en) 2011-01-24 2016-09-29 Elcam Medical Agricultural Cooperative Association Ltd. Injector
US8939943B2 (en) 2011-01-26 2015-01-27 Kaleo, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US8627816B2 (en) 2011-02-28 2014-01-14 Intelliject, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US9084849B2 (en) 2011-01-26 2015-07-21 Kaleo, Inc. Medicament delivery devices for administration of a medicament within a prefilled syringe
GB2488578B (en) * 2011-03-02 2017-05-24 Owen Mumford Ltd Injection device
AU2012231178B2 (en) * 2011-03-18 2015-11-05 Abbvie Inc. Systems, devices and methods for assembling automatic injection devices and sub-assemblies thereof
CN105413022A (en) 2011-03-29 2016-03-23 艾伯维公司 Improved Shroud Deployment In Automatic Injection Devices
JP6038884B2 (en) 2011-04-20 2016-12-07 アムゲン・インコーポレーテッド Automatic injection device
EP3020428A1 (en) 2011-04-21 2016-05-18 AbbVie Inc. Wearable automatic injection device for controlled administration of therapeutic agents
US9062106B2 (en) 2011-04-27 2015-06-23 Abbvie Inc. Methods for controlling the galactosylation profile of recombinantly-expressed proteins
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
CA2833175A1 (en) 2011-04-29 2012-11-01 Seventh Sense Biosystems, Inc. Devices and methods for collection and/or manipulation of blood spots or other bodily fluids
EP2701600B1 (en) 2011-04-29 2016-06-08 Seventh Sense Biosystems, Inc. Delivering and/or receiving fluids
WO2012162259A2 (en) 2011-05-20 2012-11-29 Excelsior Medical Corporation Caps for cannula access devices
US10166381B2 (en) 2011-05-23 2019-01-01 Excelsior Medical Corporation Antiseptic cap
US9867975B2 (en) 2011-05-23 2018-01-16 Excelsior Medical Corporation Antiseptic line cap
BR112013033500A2 (en) * 2011-06-28 2017-01-24 Alk Ag computer program method, device and product for training the use of an autoinjector
ES2797649T3 (en) 2011-07-12 2020-12-03 Icu Medical Inc Device for the delivery of antimicrobial agent in a transdermal catheter
US9814832B2 (en) 2011-09-02 2017-11-14 Unl Holdings Llc Drive mechanism for drug delivery pumps with integrated status indication
US11173244B2 (en) 2011-09-02 2021-11-16 Unl Holdings Llc Drive mechanism for drug delivery pumps with integrated status indication
EP2731641B1 (en) 2011-09-02 2021-09-29 UNL Holdings LLC Drive mechanism for drug delivery pumps with integrated status indication
US9707335B2 (en) 2011-09-02 2017-07-18 Unitract Syringe Pty Ltd Drive mechanism for drug delivery pumps with integrated status indication
BR112014005272B1 (en) * 2011-09-09 2021-01-19 Merck Patent Gmbh rechargeable autoinjector for adrenaline injection
GB2494453B (en) * 2011-09-12 2013-08-07 Owen Mumford Ltd Injector assembly
EP2758103B1 (en) * 2011-09-20 2016-06-29 Sanofi-Aventis Deutschland GmbH Cap assembly for a drug delivery device
AU2012312046B2 (en) * 2011-09-22 2017-06-01 Abbvie Inc. Automatic injection device
RU2620351C2 (en) * 2011-09-22 2017-05-24 Эббви Инк. Automated injector
MX347426B (en) * 2012-03-02 2017-04-26 Abbvie Inc Automatic injection training device.
CN104159614A (en) * 2012-03-07 2014-11-19 卡迪拉保健有限公司 Pharmaceutical formulations of TNF-alpha antibodies
WO2013135549A1 (en) * 2012-03-16 2013-09-19 Carebay Europe Ltd Medicament delivery device
US20130281540A1 (en) * 2012-03-27 2013-10-24 Borislav M. MRAVKOV Method for the Subcutaneous Administration of Parenteral Medications
US10748449B2 (en) 2012-04-04 2020-08-18 Noble International, Inc. Medicament delivery training device
EP4186545A1 (en) 2012-04-06 2023-05-31 Antares Pharma, Inc. Needle assisted jet injection administration of testosterone compositions
US10022506B2 (en) * 2012-04-11 2018-07-17 Thomas Jefferson University Hypodermic injection device incorporated in a case for a portable electronic device
CN104321095B (en) * 2012-04-13 2018-07-24 贝克顿·迪金森公司 With the injection device for being used to indicate the indicator that component suitably connects
US9181572B2 (en) 2012-04-20 2015-11-10 Abbvie, Inc. Methods to modulate lysine variant distribution
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
WO2013158279A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Protein purification methods to reduce acidic species
USD808010S1 (en) 2012-04-20 2018-01-16 Amgen Inc. Injection device
USD898908S1 (en) 2012-04-20 2020-10-13 Amgen Inc. Pharmaceutical product cassette for an injection device
US9522235B2 (en) 2012-05-22 2016-12-20 Kaleo, Inc. Devices and methods for delivering medicaments from a multi-chamber container
WO2013176754A1 (en) 2012-05-24 2013-11-28 Abbvie Inc. Novel purification of antibodies using hydrophobic interaction chromatography
WO2014023763A1 (en) * 2012-08-10 2014-02-13 Sanofi-Aventis Deutschland Gmbh Pen-type drug injection device and electronic add-on monitoring module for|monitoring and logging dose setting and administration
CA2881305C (en) 2012-08-29 2021-05-04 Unitract Syringe Pty Ltd Variable rate controlled delivery drive mechanisms for drug delivery pumps
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
WO2014035475A1 (en) 2012-09-02 2014-03-06 Abbvie Inc. Methods to control protein heterogeneity
ES2659491T3 (en) 2012-09-05 2018-03-15 E3D Agricultural Cooperative Association Ltd. Electronic self-injection device
KR101767793B1 (en) * 2012-10-11 2017-08-11 케어베이 유럽 리미티드 Automatic injection training device
BR112015009608A2 (en) 2012-10-30 2017-07-04 Truinject Medical Corp cosmetic or therapeutic training system, test tools, injection apparatus and methods for training injection, for using test tool and for injector classification
US20150290401A1 (en) * 2012-11-20 2015-10-15 The Trustees Of The University Of Pennsylvania Protective injection aid
GB2526948A (en) 2012-12-27 2015-12-09 Kaleo Inc Systems for locating and interacting with medicament delivery devices
EP2948205B1 (en) * 2013-01-25 2017-11-01 UNL Holdings LLC Drive mechanism for drug delivery pumps with integrated status indication
FI3659647T3 (en) 2013-02-11 2024-03-28 Antares Pharma Inc Needle assisted jet injection device having reduced trigger force
US8652100B1 (en) * 2013-03-08 2014-02-18 Teva Pharmaceutical Industries, Ltd. Re-useable injector device for syringe
US8591463B1 (en) 2013-03-08 2013-11-26 Teva Pharmaceutical Industries Ltd. Re-useable injector device for syringe
DK2774640T3 (en) * 2013-03-08 2015-02-02 Teva Pharma Reusable injection device for a syringe
AU2014224340B2 (en) 2013-03-08 2016-12-22 Teva Pharmaceutical Industries Limited Re-useable injector device for syringe
JP6073507B2 (en) * 2013-03-08 2017-02-01 テバ ファーマシューティカル インダストリーズ リミティド Reusable injector device for syringe
ES2742046T3 (en) 2013-03-11 2020-02-12 Antares Pharma Inc Dose injector with pinion system
EP2830651A4 (en) 2013-03-12 2015-09-02 Abbvie Inc Human antibodies that bind human tnf-alpha and methods of preparing the same
PT2968767T (en) 2013-03-14 2017-06-07 Lilly Co Eli Trigger assembly for an automatic injection device
US8921526B2 (en) 2013-03-14 2014-12-30 Abbvie, Inc. Mutated anti-TNFα antibodies and methods of their use
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
AU2014241449A1 (en) 2013-03-14 2015-08-13 Eli Lilly And Company Delay mechanism suitable for compact automatic injection device
TWI580451B (en) 2013-03-15 2017-05-01 安美基公司 Cassette for an injector and method of using an autoinjector apparatus having an autoinjector and a cassette
US10492990B2 (en) 2013-03-15 2019-12-03 Amgen Inc. Drug cassette, autoinjector, and autoinjector system
EP2781230B1 (en) 2013-03-22 2019-08-21 TecPharma Licensing AG Substance dispensing device with a signaling device
EP2784766A1 (en) 2013-03-28 2014-10-01 F. Hoffmann-La Roche AG Training device for medicine injection devices and reset device for resetting such a training device
EP3038682B1 (en) * 2013-08-29 2018-10-17 Sanofi Cap for a medicament container
WO2015051293A2 (en) 2013-10-04 2015-04-09 Abbvie, Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
MX2016004926A (en) 2013-10-16 2017-01-18 Oncobiologics Inc Buffer formulations for enhanced antibody stability.
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US8946395B1 (en) 2013-10-18 2015-02-03 Abbvie Inc. Purification of proteins using hydrophobic interaction chromatography
WO2015073884A2 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
CN103680266A (en) * 2013-11-26 2014-03-26 北京理工大学 Small-size hydromechanics experimental apparatus
US10463793B2 (en) * 2013-11-28 2019-11-05 Shl Medical Ag Shell for a medicament delivery device
BR112016014044A2 (en) 2013-12-16 2017-08-08 Walsh Jessica USABLE MEDICATION ADMINISTRATION DEVICE
CA2935864A1 (en) * 2014-01-10 2015-07-16 Sebacia, Inc. Particle containers and delivery applicators
CA2972754A1 (en) 2014-01-17 2015-07-23 Clark B. Foster Injection site training system
AU2015208397B2 (en) 2014-01-21 2017-08-10 Shl Medical Ag Injector training device
JP6296840B2 (en) * 2014-03-11 2018-03-20 テルモ株式会社 Liquid dosing device
US10290231B2 (en) 2014-03-13 2019-05-14 Truinject Corp. Automated detection of performance characteristics in an injection training system
HUE049888T2 (en) 2014-04-07 2020-11-30 Boehringer Ingelheim Int Method, electronic device, inhalation training system for practicing and/or controlling an inhalation process of a patient
ES2749050T3 (en) 2014-04-07 2020-03-18 Boehringer Ingelheim Int Inhalation training device and system to implement a patient's inhalation process
EP3137122B1 (en) 2014-05-02 2019-09-04 Excelsior Medical Corporation Strip package for antiseptic cap
JP6817074B2 (en) * 2014-06-03 2021-01-20 アムジエン・インコーポレーテツド Controllable drug delivery system and usage
FR3023170B1 (en) * 2014-07-04 2016-08-19 Aptar France Sas Autoinjector.
US9517307B2 (en) 2014-07-18 2016-12-13 Kaleo, Inc. Devices and methods for delivering opioid antagonists including formulations for naloxone
ES2751487T3 (en) * 2014-07-31 2020-03-31 Hospira Inc Injection system
TWI689326B (en) * 2014-08-06 2020-04-01 加拿大商複製細胞生命科學公司 Injection devices
US10049189B2 (en) * 2014-09-29 2018-08-14 Min Wei Method for developing parenteral therapeutic product with drug delivery device through clinical trial
EP3021245A1 (en) 2014-10-06 2016-05-18 Carebay Europe Ltd. Information provider system
WO2016078870A1 (en) * 2014-11-20 2016-05-26 Carebay Europe Ltd Automatic injection training device
KR20170102233A (en) 2014-12-01 2017-09-08 트루인젝트 코프 Injection training tool emitting omnidirectional light
CA2967899C (en) 2014-12-03 2023-09-19 Steadymed Ltd Preservative-free treprostinil formulations and methods and devices for use with same
EP3247718B1 (en) 2015-01-21 2021-09-01 Outlook Therapeutics, Inc. Modulation of charge variants in a monoclonal antibody composition
US9415176B1 (en) 2015-01-22 2016-08-16 West Pharmaceutical Services, Inc. Autoinjector having an end-of-dose visual indicator
KR20170106409A (en) * 2015-01-23 2017-09-20 더 트러스티스 오브 컬럼비아 유니버시티 인 더 시티 오브 뉴욕 Manipulated mechanically functional human cartilage and method for manufacturing the same
US20180021518A1 (en) * 2015-01-29 2018-01-25 Sanofi Trigger Mechanism and Drug Delivery Device herewith
KR101525854B1 (en) * 2015-02-06 2015-06-11 (주)엠큐어 Portable Auto Inejector
US10869966B2 (en) 2015-02-20 2020-12-22 Regeneron Pharmaceuticals, Inc. Syringe systems, piston seal systems, stopper systems, and methods of use and assembly
CA2980004C (en) 2015-03-24 2023-10-10 Kaleo, Inc. Devices and methods for delivering a lyophilized medicament
CN106139325B (en) * 2015-04-01 2020-06-26 群康生技股份有限公司 Injection pen
CN106139322A (en) * 2015-04-01 2016-11-23 群康生技股份有限公司 The locked configuration of injection pen
WO2016164817A1 (en) * 2015-04-09 2016-10-13 Leibovici Jacob Method and apparatus for applying an anesthetic and bactericide
EP3078675A1 (en) 2015-04-10 2016-10-12 Ares Trading S.A. Induction dosing regimen for the treatment of tnf alpha mediated disorders
JP6531298B2 (en) * 2015-04-24 2019-06-19 エス・ハー・エル・メディカル・アクチェンゲゼルシャフトＳｈｌ Ｍｅｄｉｃａｌ Ａｇ Drug delivery device subassembly and drug delivery device
EP3294404A4 (en) 2015-05-08 2018-11-14 ICU Medical, Inc. Medical connectors configured to receive emitters of therapeutic agents
TW201707738A (en) * 2015-06-03 2017-03-01 賽諾菲阿凡提斯德意志有限公司 Syringe support and autoinjector
WO2017004345A1 (en) 2015-06-30 2017-01-05 Kaleo, Inc. Auto-injectors for administration of a medicament within a prefilled syringe
US10810908B2 (en) * 2015-08-11 2020-10-20 Noble International, Inc. Prefilled syringe training device with releaseably locking needle guard
CA2997361C (en) * 2015-08-31 2021-02-23 Pyng Medical Corp. Intraosseous injection device
US9911364B2 (en) 2015-09-08 2018-03-06 Jbcb Holdings, Llc Resettable auto injector training device with a releasably locking shield and a resetting cap
TWI549710B (en) * 2015-09-11 2016-09-21 裕豐國際科技股份有限公司 Syringe
US10576207B2 (en) 2015-10-09 2020-03-03 West Pharma. Services IL, Ltd. Angled syringe patch injector
JP7017512B2 (en) 2015-10-09 2022-02-08 ウェスト ファーマ サービシーズ イスラエル リミテッド Bending fluid path type accessories for filled fluid containers
WO2017070391A2 (en) 2015-10-20 2017-04-27 Truinject Medical Corp. Injection system
US10529252B2 (en) 2015-11-19 2020-01-07 Noble International, Inc. Resettable shield-activated injection device trainer
TW201731538A (en) * 2015-11-27 2017-09-16 賽諾菲阿凡提斯德意志有限公司 Auto-injector device
WO2017089263A1 (en) 2015-11-27 2017-06-01 Sanofi-Aventis Deutschland Gmbh A cap for an injection device
MA44125A (en) 2015-12-27 2021-04-07 Abbvie Inc PORTABLE AUTOMATIC INJECTION DEVICE AND ASSOCIATED ASSEMBLY METHODS
JP6542481B2 (en) 2016-01-21 2019-07-10 ウェスト ファーマ サービシーズ イスラエル リミテッド system
US11311674B2 (en) 2016-01-21 2022-04-26 West Pharma. Services IL, Ltd. Medicament delivery device comprising a visual indicator
US10610638B2 (en) * 2016-01-21 2020-04-07 West Pharma. Services IL, Ltd. Force containment in an automatic injector
JP7084308B2 (en) 2016-02-03 2022-06-14 アウトルック セラピューティクス，インコーポレイティド Buffer formulation to increase antibody stability
JP6353857B2 (en) * 2016-02-17 2018-07-04 アッヴィ合同会社 Self-injection aid and self-injection system
US10980948B2 (en) * 2016-02-22 2021-04-20 West Pharmaceutical Services, Inc. Labeling apparatus for a medical device
DK3419701T3 (en) 2016-02-24 2021-11-22 Shl Medical Ag SAFETY MECHANISM FOR A MEDICINE SUPPLY DEVICE AND A MEDICINE SUPPLY DEVICE INCLUDING THE SAME
US11276328B2 (en) 2016-02-25 2022-03-15 Shl Medical Ag Automatic injection training device
WO2017151441A2 (en) 2016-02-29 2017-09-08 Truinject Medical Corp. Cosmetic and therapeutic injection safety systems, methods, and devices
WO2017151716A1 (en) 2016-03-02 2017-09-08 Truinject Medical Corp. System for determining a three-dimensional position of a testing tool
EP3423972A1 (en) 2016-03-02 2019-01-09 Truinject Corp. Sensory enhanced environments for injection aid and social training
WO2017161076A1 (en) 2016-03-16 2017-09-21 Medimop Medical Projects Ltd. Staged telescopic screw assembly having different visual indicators
USD818587S1 (en) 2016-03-29 2018-05-22 Abbevie Inc. Automatic injection device
US11318256B2 (en) 2016-04-16 2022-05-03 Shl Medical Ag Injection device
KR101844138B1 (en) 2016-05-23 2018-03-30 옥건 Functional Hair Trans Planter
GB2601424B (en) 2016-06-06 2022-12-07 E3D Agricultural Cooporative Association Ltd Multiple use computerized injector
DK3469573T3 (en) 2016-06-08 2024-03-04 Shl Medical Ag ADMINISTRATION MECHANISM FOR A DRUG DELIVERY TRAINING DEVICE
EP3474925B1 (en) 2016-06-24 2021-03-17 Avent, Inc. Bolus refill indicator
US10709845B2 (en) 2016-07-21 2020-07-14 Amgen Inc. Drug delivery device with a rotatable drive mechanism
WO2018026387A1 (en) 2016-08-01 2018-02-08 Medimop Medical Projects Ltd. Anti-rotation cartridge pin
FR3056916B1 (en) * 2016-10-04 2018-11-09 Aptar France Sas MANUAL INJECTION DEVICE.
PL3525865T3 (en) 2016-10-14 2023-02-06 Icu Medical, Inc. Sanitizing caps for medical connectors
EP3532133A1 (en) 2016-10-25 2019-09-04 Sanofi-Aventis Deutschland GmbH State indicator and drug delivery device with a state indicator and a method for manufacturing a drug delivery device
FR3058895B1 (en) 2016-11-23 2024-01-12 Nemera La Verpilliere INJECTION DEVICE HAVING AN IMPROVED SYRINGE CAP REMOVAL DEVICE
GB2557655A (en) * 2016-12-14 2018-06-27 Teva Pharma Medical injection device packaging
CA3046228A1 (en) 2016-12-23 2018-06-28 Kaleo, Inc. Medicament delivery device and methods for delivering drugs to infants and children
CN110325231B (en) 2016-12-27 2020-10-02 阿克申医药科技有限公司 Device and method for injecting a drug
CA2991391A1 (en) 2017-01-09 2018-07-09 Steadymed, Ltd. Dose sparing ketorolac formulations and methods and devices for use withsame
US20180193460A1 (en) 2017-01-09 2018-07-12 Steadymed, Ltd. Enhanced stability ketorolac formulations and methods and devices for use with same
US10332623B2 (en) 2017-01-17 2019-06-25 Kaleo, Inc. Medicament delivery devices with wireless connectivity and event detection
WO2018136901A1 (en) 2017-01-23 2018-07-26 Truinject Corp. Syringe dose and position measuring apparatus
ES2882819T3 (en) 2017-03-01 2021-12-02 Abbvie Inc Automatic injection device with near field communication
KR101811846B1 (en) * 2017-03-15 2017-12-22 김휘화 Safety improved semi-automatic syringe
JP2020515530A (en) 2017-03-26 2020-05-28 マピ ファーマ リミテッド Glatiramer depot system for treating progressive multiple sclerosis
TWI630938B (en) * 2017-04-25 2018-08-01 群康生技股份有限公司 Injection pen
CN110545863B (en) * 2017-04-25 2021-06-01 群康生技股份有限公司 Injection pen
WO2018204206A2 (en) 2017-05-01 2018-11-08 Icu Medical, Inc. Medical fluid connectors and methods for providing additives in medical fluid lines
AU2018265624A1 (en) 2017-05-11 2019-12-05 Steadymed, Ltd. Enhanced solubility drug-containing formulations
WO2018222521A1 (en) 2017-05-30 2018-12-06 West Pharma. Services IL, Ltd. Modular drive train for wearable injector
KR101939061B1 (en) * 2017-06-22 2019-01-17 (주)엠큐어 Injector capable of metering
IL308235A (en) 2017-06-30 2024-01-01 Regeneron Pharma Auto-injector with anti-roll features
AU2018303227A1 (en) 2017-07-21 2020-02-20 Becton Dickinson France Assisted injection device for injecting a composition contained in a medical container with reduced efforts
US20200349864A1 (en) * 2017-10-24 2020-11-05 Phokus Research Group, Llc Technologies for wound treatment education
WO2019147220A1 (en) * 2018-01-23 2019-08-01 Ows Agri Limited System and method for ozone concentration measurement in ice
JP7284186B2 (en) 2018-04-04 2023-05-30 シェイリー エンジニアリング プラスチックス リミテッド automatic syringe
US11844914B2 (en) * 2018-06-05 2023-12-19 Edwards Lifesciences Corporation Removable volume indicator for syringe
WO2020014292A1 (en) 2018-07-10 2020-01-16 Action Medical Technologies, Llc Apparatuses and method for injecting medicaments
WO2020018433A1 (en) 2018-07-16 2020-01-23 Kaleo, Inc. Medicament delivery devices with wireless connectivity and compliance detection
US11534595B2 (en) 2018-11-07 2022-12-27 Icu Medical, Inc. Device for delivering an antimicrobial composition into an infusion device
US11541221B2 (en) 2018-11-07 2023-01-03 Icu Medical, Inc. Tubing set with antimicrobial properties
US11400195B2 (en) 2018-11-07 2022-08-02 Icu Medical, Inc. Peritoneal dialysis transfer set with antimicrobial properties
US11517732B2 (en) 2018-11-07 2022-12-06 Icu Medical, Inc. Syringe with antimicrobial properties
US11541220B2 (en) 2018-11-07 2023-01-03 Icu Medical, Inc. Needleless connector with antimicrobial properties
WO2020106985A1 (en) 2018-11-21 2020-05-28 Pursuit Vascular, Inc. Antimicrobial device comprising a cap with ring and insert
USD893712S1 (en) 2019-02-15 2020-08-18 Action Medical Technologies, Llc Grip for autoinjectors
JP6997882B2 (en) * 2019-03-15 2022-01-18 イーライ リリー アンド カンパニー Injection system
CN109907858B (en) * 2019-04-12 2024-02-09 山东省农业科学院奶牛研究中心 Injector extension device for dairy cows
CN110400509B (en) * 2019-07-30 2021-04-13 宁波睿爱产品设计有限公司 Injection training device with sound prompt function
CA3145580A1 (en) 2019-08-09 2021-02-18 Kaleo, Inc. Devices and methods for delivery of substances within a prefilled syringe
US20220265930A1 (en) * 2019-09-03 2022-08-25 Asahi Kasei Pharma Corporation Automatic injection device
JP7323240B2 (en) 2020-03-25 2023-08-08 アクション メディカル テクノロジーズ，エルエルシー Apparatus and method for infusing drugs
CN115379870A (en) * 2020-04-03 2022-11-22 赛诺菲 Syringe device
US11759576B2 (en) 2020-06-05 2023-09-19 Action Medical Technologies, Llc Parenteral injection apparatus
CA3204371A1 (en) 2020-12-07 2022-06-16 Icu Medical, Inc. Peritoneal dialysis caps, systems and methods
CN112842485B (en) * 2021-01-20 2022-02-08 上海埃斯埃医疗技术有限公司 Emitter based on platform resets
EP4039294A1 (en) 2021-02-05 2022-08-10 Ruslan Ravilievich Muratov Autoinjector
EP4313220A1 (en) * 2021-04-01 2024-02-07 Pulse NeedleFree Systems, Inc. Injection device with injection completion indicator
WO2022221162A1 (en) * 2021-04-16 2022-10-20 Merck Sharp & Dohme Llc Injection delivery devices for injecting highly viscous medicaments
CN113257385B (en) * 2021-05-12 2023-10-20 北京市垂杨柳医院 Drug injection system based on image and voice recognition
CN113499513B (en) * 2021-06-28 2022-12-20 苏州赛卫生物科技有限公司 Automatic injection pen
CN114366250B (en) * 2021-12-31 2023-09-05 杭州德柯医疗科技有限公司 Sleeve, injection device, injection system, ablation device and ablation system
WO2023139423A1 (en) * 2022-01-20 2023-07-27 Orbicular Pharmaceutical Technologies Private Limited Vitamin k1 injection device kit
US20240091765A1 (en) * 2022-02-15 2024-03-21 Todd Michael Haran Multistage fluidic device
US20240058540A1 (en) * 2022-04-27 2024-02-22 Medmix Switzerland Ag Cartridge holding unit
EP4295874A1 (en) * 2022-06-22 2023-12-27 medmix Switzerland AG Set of a medicament delivery device and a cover
WO2023244789A1 (en) * 2022-06-16 2023-12-21 Stryker Corporation Infusion module for an electrosurgical instrument
CN115990303B (en) * 2023-03-23 2023-06-27 山东安得医疗用品股份有限公司 Sliding block type negative pressure suction injector
CN116570504A (en) * 2023-06-02 2023-08-11 南京原子高科医药有限公司 Automatic injection device for radioactive therapeutic drug

Family Cites Families (516)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2459875A (en) * 1944-09-11 1949-01-25 Marvin L Folkman Syringe and ampoule
US2398544A (en) 1945-01-06 1946-04-16 Marshall L Lockhart Hypodermic injector
US2565081A (en) 1948-09-15 1951-08-21 Emma C Maynes Device for operating hypodermic syringes
US2591457A (en) 1948-09-15 1952-04-01 Emma C Maynes Syringe operating device
DE902776C (en) 1949-08-17 1954-01-28 August Rooseboom Automatic injection device with ampoule
US2701566A (en) * 1950-02-07 1955-02-08 Becton Dickinson Co Injection apparatus
US2751918A (en) 1950-12-28 1956-06-26 Honeywell Regulator Co Manually or automatically actuated air-pressure-responsive controller
BE531562A (en) 1953-09-02
US2960087A (en) 1954-02-16 1960-11-15 Auguste Rooseboom Hypodermic injection apparatus
DK97966C (en) 1954-10-27 1964-02-10 Astra Apotekarnes Kem Fab Syringe.
US3055362A (en) 1956-05-16 1962-09-25 Auguste Rooseboom Hypodermic injection apparatus
NL106573C (en) 1957-05-31
US2888924A (en) 1958-02-25 1959-06-02 Russell P Dunmire Hypodermic syringes
US3051173A (en) 1960-05-12 1962-08-28 Alvin P Johnson Veterinary hypodermic syringe
US3330279A (en) 1963-10-18 1967-07-11 Sarnoff Automatic hypodermic syringe
US3314428A (en) 1963-12-04 1967-04-18 Alvin P Johnson Veterinary hypodermic syringe
US3403679A (en) 1964-12-11 1968-10-01 Secr Defence Brit Hypodermic injection apparatus with a secondary capsule-collapsing means
US3426448A (en) * 1967-02-02 1969-02-11 Stanley J Sarnoff Training injection device
US3496937A (en) * 1967-05-18 1970-02-24 John E Balson Hypodermic syringe
US3543603A (en) 1968-01-10 1970-12-01 Rex Chainbelt Inc Automatic quick release mechanism
US3541663A (en) 1968-08-21 1970-11-24 Roman Szpur Syringe needle attachment device
US3605743A (en) 1968-10-14 1971-09-20 Raul Olvera Arce Hypodermic syringe
DE1957833A1 (en) 1968-11-21 1970-07-02 Maurice Steiner Injection syringe, especially injection syringe handled by the patient himself
US3618603A (en) 1969-01-29 1971-11-09 Levenson M F Syringe
BE755224A (en) 1969-08-25 1971-02-24 Philips Nv INJECTION SYRINGE
DE2019296A1 (en) 1970-04-22 1971-11-04 Walter Dr Stein Injection device, in particular injection syringe with portioned pack
US3712301A (en) * 1971-01-11 1973-01-23 Survival Technology Gun type hypodermic injector with rapid cartridge displacement within holder
BE795162A (en) * 1972-02-10 1973-08-08 Philips Nv INJEKTIE-INRICHTING
US3910260A (en) 1972-03-01 1975-10-07 Survival Technology Method and apparatus of treating heart attack patients prior to the establishment of qualified direct contact personal care
US3797488A (en) * 1972-07-10 1974-03-19 Ampoules Inc Ampoule applicator with one-way clutch
US4004577A (en) * 1972-12-04 1977-01-25 Survival Technology, Inc. Method of treating heart attack patients prior to the establishment of qualified direct contact personal care
US3795061A (en) 1973-03-21 1974-03-05 Survival Technology Training injector
FR2237643B1 (en) 1973-07-17 1978-03-17 Steiner Maurice
US3882863A (en) 1973-08-01 1975-05-13 Survival Technology Hypodermic injection device having cannula covered with resilient sheath
US3941130A (en) * 1975-03-18 1976-03-02 Tibbs Robert C Sequential trigger release for injection device
US4031893A (en) 1976-05-14 1977-06-28 Survival Technology, Inc. Hypodermic injection device having means for varying the medicament capacity thereof
US4106770A (en) 1976-09-01 1978-08-15 Gray John M Hypodermic syringe projectile
US4178928A (en) 1977-08-10 1979-12-18 Tischlinger Edward A Self injector
SU787035A1 (en) 1978-01-11 1980-12-15 Всесоюзный научно-исследовательский и испытательный институт медицинской техники Device for injection of medical preparations
US4202314A (en) 1978-11-20 1980-05-13 Busygin Valery P Device for injection of medicinal preparations
US4226235A (en) 1979-01-25 1980-10-07 Survival Technology, Inc. Plural injecting device
US4258713A (en) * 1979-07-23 1981-03-31 Wardlaw Stephen C Automatic disposable hypodermic syringe
US4261358A (en) 1979-10-01 1981-04-14 Walter Vargas Automatic syringe plunger
US4275729A (en) 1979-10-29 1981-06-30 Jules Silver Adjustable dosage syringe
US5179017A (en) * 1980-02-25 1993-01-12 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4634665A (en) * 1980-02-25 1987-01-06 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4399216A (en) 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
AU549690B2 (en) 1981-06-29 1986-02-06 Sherwood Services Ag Pin prick device to pierce skin
ATE15860T1 (en) 1981-07-27 1985-10-15 Duphar Int Res AUTOMATIC INJECTION SYRINGE.
US4437859A (en) * 1981-08-03 1984-03-20 Drs Infusion Systems, Inc. Hydraulic syringe drive
US4394863A (en) 1981-10-23 1983-07-26 Survival Technology, Inc. Automatic injector with cartridge having separate sequentially injectable medicaments
US4425120A (en) * 1982-04-15 1984-01-10 Sampson Norma A Shielded hypodermic syringe
EP0107874B1 (en) * 1982-10-27 1986-11-26 Duphar International Research B.V Automatic injection device
US4510245A (en) 1982-11-18 1985-04-09 Chiron Corporation Adenovirus promoter system
US4530695A (en) 1982-12-31 1985-07-23 N.J. Phillips Pty. Limited Injector
GB8308235D0 (en) * 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4578064A (en) * 1983-12-21 1986-03-25 Survival Technology Inc. Plural dosage automatic injector with improved safety
DE3572982D1 (en) 1984-03-06 1989-10-19 Takeda Chemical Industries Ltd Chemically modified lymphokine and production thereof
US4619265A (en) 1984-03-08 1986-10-28 Physio-Control Corporation Interactive portable defibrillator including ECG detection circuit
US4610254A (en) 1984-03-08 1986-09-09 Physio-Control Corporation Interactive portable defibrillator
US4573976A (en) * 1984-05-24 1986-03-04 Dolores A. Smith Shielded needle
US4795433A (en) * 1985-05-20 1989-01-03 Survival Technology, Inc. Automatic injector for emergency treatment
JPS6147500A (en) 1984-08-15 1986-03-07 Res Dev Corp Of Japan Chimera monoclonal antibody and its preparation
EP0173494A3 (en) 1984-08-27 1987-11-25 The Board Of Trustees Of The Leland Stanford Junior University Chimeric receptors by dna splicing and expression
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
US4678461A (en) 1984-11-01 1987-07-07 Survival Technology, Inc. Automatic injector with improved glass container protector
DE3566866D1 (en) 1984-11-02 1989-01-26 Duphar Int Res Automatic injection device
JPS61134325A (en) 1984-12-04 1986-06-21 Teijin Ltd Expression of hybrid antibody gene
US5168062A (en) 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
US4627445A (en) * 1985-04-08 1986-12-09 Garid, Inc. Glucose medical monitoring system
US4689042A (en) 1985-05-20 1987-08-25 Survival Technology, Inc. Automatic medicament ingredient mixing and injecting apparatus
US4723937A (en) * 1985-05-20 1988-02-09 Survival Technology, Inc. Plural dosage automatic injector with a by-pass fitment
WO1987002254A1 (en) 1985-10-11 1987-04-23 Physionic Gesellschaft Für Medizin- Und Systemtech Injection syringe
EP0219899B1 (en) 1985-10-11 1990-08-08 Duphar International Research B.V Automatic injector
DE3689123T2 (en) 1985-11-01 1994-03-03 Xoma Corp MODULAR UNIT OF ANTIBODY GENES, ANTIBODIES MADE THEREOF AND USE.
US4968615A (en) 1985-12-18 1990-11-06 Ciba-Geigy Corporation Deoxyribonucleic acid segment from a virus
US4664653A (en) 1986-02-24 1987-05-12 Sagstetter William E Manually operated reusable injection apparatus
US4640686A (en) * 1986-02-24 1987-02-03 Survival Technology, Inc. Audible signal autoinjector training device
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
ES2024489B3 (en) 1986-05-15 1992-03-01 Duphar Int Res B V AUTOMATIC INJECTOR.
DE3631229A1 (en) 1986-09-13 1988-03-24 Basf Ag MONOCLONAL ANTIBODIES AGAINST HUMAN TUMORNESCROSE FACTOR (TNF) AND THEIR USE
DE3638984C3 (en) 1986-11-14 1993-11-18 Haselmeier Wilhelm Fa Injection device
US4795432A (en) * 1987-02-19 1989-01-03 Karczmer Claude M Shield assembly for hypodermic injection devices
DE3709783C1 (en) 1987-03-25 1988-04-14 Blendax Werke Schneider Co Dosing syringe
DE3715340C2 (en) 1987-05-08 1995-10-19 Haselmeier Wilhelm Fa Injection device
DE3715258C2 (en) * 1987-05-08 1996-10-31 Haselmeier Wilhelm Fa Injection device
NL8701091A (en) * 1987-05-08 1988-12-01 Spruyt Hillen Bv INJECTION PEN.
US4927416A (en) 1987-12-02 1990-05-22 National Medical Device Corporation User-protective hypodermic syringe holder
GB8809115D0 (en) 1988-04-18 1988-05-18 Turner R C Syringes
EP0404954B1 (en) 1988-07-28 2002-10-02 Idemitsu Petrochemical Co., Ltd. Rubber-modified styrene resin composition
GB8819977D0 (en) 1988-08-23 1988-09-21 Medimech Ltd Automatic injectors
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US4902279A (en) * 1988-10-05 1990-02-20 Autoject Systems Inc. Liquid medicament safety injector
US5244465A (en) 1988-10-19 1993-09-14 Byk Gulden Lomberg Chemische Fabrik Gmbh Reusable injection device for distributing a preselected dose
US4929237A (en) 1988-11-07 1990-05-29 David Medway Hypodermic needle protection device
US4955868A (en) 1988-11-28 1990-09-11 Edward Klein Disposable safety medical syringe
IT1227658B (en) 1988-12-01 1991-04-23 Vittorio Boschetti B DISPOSABLE SYRINGE WITH RETURN AND NEEDLE LOCK AT THE END OF INJECTION FOR THE PURPOSE OF AVOID RE-USE
EP0401384B1 (en) 1988-12-22 1996-03-13 Kirin-Amgen, Inc. Chemically modified granulocyte colony stimulating factor
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
ES2019792A6 (en) 1990-01-17 1991-07-01 Caralt Batlle Jaime Disposable hypodermic syringe.
ES2009709A6 (en) 1989-01-24 1989-10-01 Villar Pascual Jose Antonio Single-use safety syringe
US4923447A (en) 1989-02-17 1990-05-08 Morgan Michael W Syringe assembly
ES2036885T3 (en) * 1989-03-28 1993-06-01 Duphar International Research B.V A PRE-LOADED INJECTION DEVICE COMPRISING A CYLINDRICAL BODY IN WHICH A LIQUID FORMULATION OF DIAZEPAM IS ACCOMMODATED.
US4966592A (en) 1989-05-05 1990-10-30 Burns Cameron A Protective sleeve for hypodermic needle
USD322479S (en) 1989-06-02 1991-12-17 Terumo Kabushiki Kaisha Holder for lancet
US4994034A (en) * 1989-07-11 1991-02-19 Botich Michael J Retractable needle hypodermic syringe system
US5407431A (en) * 1989-07-11 1995-04-18 Med-Design Inc. Intravenous catheter insertion device with retractable needle
US5085642A (en) * 1989-07-17 1992-02-04 Survival Technology, Inc. Conveniently carried frequent use autoinjector
US5102393A (en) 1989-07-17 1992-04-07 Survival Technology, Inc. Autoinjector converted from intramuscular to subcutaneous mode of injection
US5085641A (en) * 1989-07-17 1992-02-04 Survival Technology, Inc. Conveniently carried frequent use auto-injector with improved cap structure
US5959087A (en) 1989-08-07 1999-09-28 Peptide Technology, Ltd. Tumour necrosis factor binding ligands
US6448380B2 (en) 1989-08-07 2002-09-10 Peptech Limited Tumor necrosis factor antibodies
CA2065346C (en) 1989-09-05 2005-03-29 Craig A. Smith Tumor necrosis factor-.alpha. and-.beta. receptors
EP0423864A1 (en) * 1989-10-16 1991-04-24 Duphar International Research B.V Training device for an automatic injector
EP0425003A1 (en) * 1989-10-24 1991-05-02 Duphar International Research B.V Training device for an automatic injector
GB8926825D0 (en) 1989-11-28 1990-01-17 Glaxo Group Ltd Device
GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
US5267976A (en) 1990-03-08 1993-12-07 Blue Star Corporation S.A. Syringe with self-retracting needle
GB2243552A (en) 1990-03-21 1991-11-06 Transfertec Limited Improvements in or relating to single-use syringes
US5092843A (en) * 1990-04-12 1992-03-03 Survival Technology, Inc. Dispersion multichamber auto-injector
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
DK0585287T3 (en) 1990-07-10 2000-04-17 Cambridge Antibody Tech Process for producing specific binding pair elements
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
ATE129906T1 (en) 1990-07-19 1995-11-15 Nardino Righi SINGLE USE SAFETY SYRINGE.
DK285990A (en) 1990-11-30 1992-05-31 Nujenko Pty Ltd SPRAY UNIT
DK0564531T3 (en) 1990-12-03 1998-09-28 Genentech Inc Enrichment procedure for variant proteins with altered binding properties
AU114410S (en) * 1990-12-21 1992-06-29 Glaxo Group Ltd An injector
GB9100819D0 (en) * 1991-01-15 1991-02-27 Medimech Int Ltd Subcutaneous injector
US5376080A (en) 1991-01-30 1994-12-27 Petrussa; Gian L. Single use retractable needle syringe
ES2287206T3 (en) 1991-03-01 2007-12-16 Dyax Corporation PROCESS FOR THE DEVELOPMENT OF MINI-PROTEINS OF UNION.
US5656272A (en) 1991-03-18 1997-08-12 New York University Medical Center Methods of treating TNF-α-mediated Crohn's disease using chimeric anti-TNF antibodies
IE921169A1 (en) 1991-04-10 1992-10-21 Scripps Research Inst Heterodimeric receptor libraries using phagemids
GB9111600D0 (en) * 1991-05-30 1991-07-24 Owen Mumford Ltd Improvements relating to injection devices
EP0518416A1 (en) 1991-06-13 1992-12-16 Duphar International Research B.V Injection device
RU2004256C1 (en) 1991-06-26 1993-12-15 Липов Борис Петрович, Сафронов Игорь Николаевич Injector
DE4122599C2 (en) 1991-07-08 1993-11-11 Deutsches Krebsforsch Phagemid for screening antibodies
ATE121953T1 (en) * 1991-07-24 1995-05-15 Medico Dev Investment Co INJECTOR.
US5259840A (en) 1991-09-03 1993-11-09 Boris Craig R Locking syringe
WO1993006213A1 (en) 1991-09-23 1993-04-01 Medical Research Council Production of chimeric antibodies - a combinatorial approach
US5242240A (en) 1991-10-17 1993-09-07 Minnesota Scientific, Inc. Clamping device for a surgical retractor
USD346219S (en) 1991-11-25 1994-04-19 Actimed Plast AB Erection pump
US5263934A (en) 1991-11-28 1993-11-23 Haak Abraham Van Den Stroke limiting syringe with retractable needle
DK194291D0 (en) 1991-11-29 1991-11-29 Novo Nordisk As SPRAY FOR AUTOMATIC INJECTION.
EP0620748B1 (en) 1992-01-07 2010-07-28 Meridian Medical Technologies, Inc. Automatic injectors
GB9200219D0 (en) * 1992-01-07 1992-02-26 Medimech Int Ltd Automatic injectors
AT398037B (en) 1992-01-10 1994-08-25 Med Plastic Ag DEVICE FOR SELF-INJECTION
US5201708A (en) 1992-02-03 1993-04-13 Timothy A. Kershenstine Self-locking safety syringe
EP0562671B1 (en) 1992-03-27 1996-05-29 Duphar International Research B.V Automatic injector
US5605923A (en) 1992-04-02 1997-02-25 Smithkline Beecham Corporation Compounds useful for treating inflammatory diseases and inhibiting production of tumor necrosis factor
US5271527A (en) * 1992-04-02 1993-12-21 Habley Medical Technology Corporation Reusable pharmaceutical dispenser with full stroke indicator
US5267972A (en) 1992-07-20 1993-12-07 Anderson Wayne W Hypodermic syringe with needle guard
US5267963A (en) 1992-08-21 1993-12-07 Nicholas Bachynsky Medication injection device
CA2123593C (en) 1992-09-15 2000-03-14 Craig A. Smith Method of treating tnf-dependent inflammation using tumor necrosis factor antagonists
GB9219849D0 (en) 1992-09-19 1992-10-28 Hypoguard Uk Ltd Device
US6270766B1 (en) 1992-10-08 2001-08-07 The Kennedy Institute Of Rheumatology Anti-TNF antibodies and methotrexate in the treatment of arthritis and crohn's disease
CA2147180A1 (en) 1992-10-15 1994-04-28 Gokhan S. Hotamisligil Treatment of insulin resistance in obesity linked type ii diabetes using antagonists to tnf-.alpha. function
US5224936A (en) 1992-10-15 1993-07-06 Brian Gallagher Automatic self-protecting hypodermic needle assembly
US5295975A (en) * 1992-10-28 1994-03-22 Lockwood Jr Hanford N Hypodermic needle safety device with sliding outer cover
US5334144A (en) 1992-10-30 1994-08-02 Becton, Dickinson And Company Single use disposable needleless injector
GB9223183D0 (en) 1992-11-05 1992-12-16 Medimech Int Ltd Improvements related to auto injectors
US5378233A (en) * 1992-11-18 1995-01-03 Habley Medical Technology Corporation Selected dose pharmaceutical dispenser
US5681291A (en) 1992-11-19 1997-10-28 Tebro S.A. Disposable auto-injector for prefilled syringes
US5320609A (en) 1992-12-07 1994-06-14 Habley Medical Technology Corporation Automatic pharmaceutical dispensing syringe
IT1256577B (en) 1992-12-11 1995-12-11 Ermanno Greco DEVICE PREPARED FOR THE AUTOMATIC ADMINISTRATION OF A DRUG VIA INTRADERMIC.
US5346480A (en) 1992-12-14 1994-09-13 Q-Med, Inc. Syringe with retractable needle
US5298024A (en) * 1992-12-28 1994-03-29 Frank Richmond Multi-liquid medicament delivery system with reflex valves
FR2701211B1 (en) 1993-02-08 1995-05-24 Aguettant Lab DOSING INSTRUMENT, ESPECIALLY INJECTION
US5383865A (en) * 1993-03-15 1995-01-24 Eli Lilly And Company Medication dispensing device
DE69427226T2 (en) * 1993-03-24 2001-08-30 Owen Mumford Ltd DEVICE FOR INJECTION
DK55693D0 (en) 1993-05-13 1993-05-13 Radiometer As SHOOTING MECHANISM FOR SHOOTING A CANNEL LOCATED IN CONNECTION WITH A CONTAINER, AND A CONTAINER TOPIC INCLUDING SUCH A SHOOTING MECHANISM
US5540664A (en) 1993-05-27 1996-07-30 Washington Biotech Corporation Reloadable automatic or manual emergency injection system
US5358489A (en) 1993-05-27 1994-10-25 Washington Biotech Corporation Reloadable automatic or manual emergency injection system
US5433712A (en) 1993-06-10 1995-07-18 Donald E. Stiles Self-sheathing hypodermic syringe
US5425715A (en) 1993-08-05 1995-06-20 Survival Technology, Inc. Reloadable injector
US5620421A (en) 1993-12-09 1997-04-15 Schmitz; William L. Syringe injector system
FR2715071B1 (en) 1994-01-17 1996-03-01 Aguettant Lab Automatic drug injector.
US5478316A (en) 1994-02-02 1995-12-26 Becton, Dickinson And Company Automatic self-injection device
EP1228777B1 (en) 1994-05-30 2003-10-29 B D Medico S.a.r.l. Injection device
GB9412301D0 (en) 1994-06-17 1994-08-10 Safe T Ltd Hollow-needle drugs etc applicators
US5645534A (en) 1994-06-24 1997-07-08 Becton Dickinson And Company Time of last injection indicator for medication delivery pen
EP0955951B1 (en) 1994-07-01 2005-08-24 Edwards Lifesciences Corporation Device for harvesting adipose tissue containing autologous microvascular endothelial cells
US5637094A (en) 1994-11-04 1997-06-10 Pos-T-Vac, Inc. Multiple dosage syringe
RU2069584C1 (en) 1994-11-24 1996-11-27 Виктор Владимирович Барелко Catalyst for chemical processes, in particular, for conversion of ammonia, oxidation of hydrocarbons, sulfur dioxide, and for purification of gases
US5993421A (en) 1994-12-02 1999-11-30 Science Incorporated Medicament dispenser
GB9504878D0 (en) 1995-03-10 1995-04-26 Weston Medical Ltd Viscously coupled actuator
US6319011B1 (en) 1995-04-06 2001-11-20 Michael J. Motti Automatic training defibrillator simulator and method
FR2733155B1 (en) 1995-04-18 1997-09-19 Tebro RECHARGEABLE SELF-INJECTOR
FR2736553B1 (en) 1995-07-12 1998-01-09 Soc Et Et D Applic Tech Sedat INJECTION SYRINGE, IN PARTICULAR LIQUID MEDICAL PRODUCTS, WITH MOBILE NEEDLE PROTECTOR
US5645571B1 (en) 1995-08-01 1999-08-24 Surviva Link Corp Automated external defibrillator with lid activated self-test system
US5797969A (en) 1995-08-01 1998-08-25 Survivalink Corporation One button lid activated automatic external defibrillator
EP1419798A3 (en) 1995-08-08 2005-08-31 Cardiac Science, Inc. Automated external defibrillator
EP1637181A1 (en) 1995-08-08 2006-03-22 Cardiac Science, Inc. Automated external defibrillator
DE69631722T2 (en) 1995-08-08 2005-04-07 Cardiac Science, Inc., Minneapolis Automated external defibrillation with self-test system
US5591138A (en) * 1995-08-10 1997-01-07 Vaillancourt; Vincent L. Protected needle assembly
US5735818A (en) * 1995-10-11 1998-04-07 Science Incorporated Fluid delivery device with conformable ullage
US5658259A (en) 1995-10-19 1997-08-19 Meridian Medical Technologies, Inc. Dental cartridge assembly auto-injector with protective needle cover
US5567160A (en) 1995-10-26 1996-10-22 Survival Technology, Inc. Autoinjector training device
US6090382A (en) * 1996-02-09 2000-07-18 Basf Aktiengesellschaft Human antibodies that bind human TNFα
US5807335A (en) * 1995-12-22 1998-09-15 Science Incorporated Fluid delivery device with conformable ullage and fill assembly
US5634906A (en) 1995-12-27 1997-06-03 Habley Medical Technology Corporation Needle hiding shield for a dose metering syringe
NZ536216A (en) * 1996-02-09 2006-08-31 Abbott Biotech Ltd Use of an isolated antibody D2E7 for the treatment of a disorder in which TNF(alpha) activity is detrimental
DE19604838A1 (en) 1996-02-12 1997-08-14 Alfred Von Schuckmann Device for dispensing liquid in divided quantities
AU718205B2 (en) 1996-03-12 2000-04-13 Novo Nordisk A/S Injection device with electronic presentation of set doses
US5817111A (en) 1996-03-28 1998-10-06 Riza; Erol D. Open loop suture snare
IT1284642B1 (en) 1996-05-02 1998-05-21 Ermanno Greco REFINEMENTS FOR AUTOMATIC SYRINGES FOR INJECTION
EP1579814A3 (en) * 1996-05-17 2006-06-14 Roche Diagnostics Operations, Inc. Methods and apparatus for sampling and analyzing body fluid
GB9612724D0 (en) 1996-06-18 1996-08-21 Owen Mumford Ltd Improvements relating to injection devices
US6090080A (en) 1996-07-05 2000-07-18 Disetronic Licensing Ag Injection device for injection of liquid
US5843036A (en) * 1996-08-23 1998-12-01 Becton Dickinson And Company Non-dosing cartridge for an injection device
US5845644A (en) 1996-08-26 1998-12-08 Hughes; Charles B. Bladder and bowel training system
US6325066B1 (en) 1996-08-26 2001-12-04 Charles B. Hughes Bladder and bowel training system with removable voice module system
NZ335864A (en) * 1996-11-06 2001-09-28 Univ California Isolated tumor necrosis factor receptor releasing enzyme (TRRE), compositions comprising the enzyme and methods of the use in modulation of TNF levels
US6593456B1 (en) * 1996-11-06 2003-07-15 The Regents Of The University Of California Tumor necrosis factor receptor releasing enzyme
SE9604162D0 (en) 1996-11-13 1996-11-13 Astra Ab membrane
US6203530B1 (en) * 1997-01-28 2001-03-20 Pos-T-Vac, Inc. Auto-injection device
US20070142776A9 (en) 1997-02-05 2007-06-21 Medtronic Minimed, Inc. Insertion device for an insertion set and method of using the same
BR9700930A (en) 1997-02-07 1998-12-08 Rhone Poulenc Rorer Gmbh Unit for sale intended for parenteral application a device for the execution of parenteral application as well as a refill unit for the above mentioned unit for sale
US5860957A (en) * 1997-02-07 1999-01-19 Sarcos, Inc. Multipathway electronically-controlled drug delivery system
WO1998035714A1 (en) 1997-02-12 1998-08-20 Sergio Restelli Disposable safety syringe
DE29703820U1 (en) 1997-03-03 1998-07-02 Medico Dev Investment Co Injection device
US20010020155A1 (en) 1997-03-25 2001-09-06 Soren Mikkelsen Injection system
US6454746B1 (en) 1997-06-04 2002-09-24 Eli Lilly And Company Medication delivery apparatus
US6500150B1 (en) 1997-06-16 2002-12-31 Elan Pharma International Limited Pre-filled drug-delivery device and method of manufacture and assembly of same
US6979307B2 (en) 1997-06-24 2005-12-27 Cascade Medical Enterprises Llc Systems and methods for preparing autologous fibrin glue
GB9714948D0 (en) 1997-07-16 1997-09-17 Owen Mumford Ltd Improvements relating to injection devices
GB9716065D0 (en) * 1997-07-31 1997-10-01 Owen Mumford Ltd Improvements relating to injection devices
CA2300930C (en) 1997-08-21 2007-10-16 Owen Mumford Limited Improvements relating to injection devices
US5931817A (en) 1997-09-12 1999-08-03 Becton Dickinson And Company Pen needle assembly
WO1999016485A1 (en) * 1997-09-29 1999-04-08 Becton Dickinson And Company Injection device and drug cartridge for preventing cross-use of the device and drug cartridge
US6149626A (en) 1997-10-03 2000-11-21 Bachynsky; Nicholas Automatic injecting syringe apparatus
WO1999022792A1 (en) 1997-11-03 1999-05-14 Ermanno Greco Self-injection device
FR2770404B1 (en) 1997-11-05 2000-01-28 Sedat AUTOMATIC INJECTOR WITH NEEDLE RETRACTION AT THE END OF INJECTION
EP1039942B1 (en) 1997-12-16 2004-10-13 Meridian Medical Technologies, Inc. Automatic injector for administrating a medicament
IT1304761B1 (en) 1998-01-20 2001-03-29 Nardino Righi DISPOSABLE SAFETY SYRINGE.
DE29801168U1 (en) 1998-01-24 1999-08-12 Medico Dev Investment Co Injection device
FR2774294B1 (en) 1998-02-04 2000-04-14 Marc Brunel DEVICE FOR AUTOMATICALLY INJECTING A DOSE OF MEDICINAL PRODUCT
US7056306B1 (en) 1998-02-05 2006-06-06 Mdc Investment Holdings, Inc. Fluid sampling device with retractable needle
GB9803084D0 (en) 1998-02-14 1998-04-08 Owen Mumford Ltd Improvements relating to medical injection devices
FI109272B (en) 1998-02-26 2002-06-28 Raimo Juselius Intake event detector and method for detecting intake event
US6319233B1 (en) 1998-04-17 2001-11-20 Becton, Dickinson And Company Safety shield system for prefilled syringes
GB9808408D0 (en) 1998-04-18 1998-06-17 Owen Mumford Ltd Improvements relating to injection devices
DE19822031C2 (en) 1998-05-15 2000-03-23 Disetronic Licensing Ag Auto injection device
DE19821933C1 (en) 1998-05-15 1999-11-11 Disetronic Licensing Ag Device for administering an injectable product
USD428651S (en) 1998-10-26 2000-07-25 Pharmacia & Upjohn Ab Autoinjector for standardized single dose syringes
SE9803662D0 (en) 1998-10-26 1998-10-26 Pharmacia & Upjohn Ab autoinjector
US6125299A (en) 1998-10-29 2000-09-26 Survivalink Corporation AED with force sensor
US6641565B1 (en) 1998-11-13 2003-11-04 Elan Pharma International Limited drug delivery systems and methods
WO2000030712A1 (en) 1998-11-20 2000-06-02 Medtronic Physio-Control Manufacturing Corp. Visual and aural user interface for an automated external defibrillator
US20060058848A1 (en) 1998-11-20 2006-03-16 Medtronic Emergency Response Systems, Inc. AED with user inputs in response to prompts
US6312412B1 (en) 1998-12-02 2001-11-06 V. C. Saied, M.D. Apparatus and method for painless intramuscular or subcutaneous injections
US6872080B2 (en) 1999-01-29 2005-03-29 Cardiac Science, Inc. Programmable AED-CPR training device
GB9903475D0 (en) 1999-02-17 1999-04-07 Owen Mumford Ltd Improvements relating to injection devices
AU6414400A (en) 1999-07-27 2001-02-13 Pharma Consult Ges.M.B.H. Device for automatically injecting injection liquids
US6213987B1 (en) 1999-08-02 2001-04-10 Michael N. Hirsch Shroud for a used hypodermic syringe needle
US6277099B1 (en) 1999-08-06 2001-08-21 Becton, Dickinson And Company Medication delivery pen
JP2003508164A (en) 1999-09-07 2003-03-04 コンピューター・コントロールド・シリンジ・インコーポレーテッド Retractable needle device
US6102896A (en) 1999-09-08 2000-08-15 Cambridge Biostability Limited Disposable injector device
EP1257307A2 (en) * 1999-09-13 2002-11-20 Vitro Diagnostics, Inc. Multi-dose syringe driver
US6171285B1 (en) * 1999-10-06 2001-01-09 R. Steven Johnson Retractable syringe
US6673035B1 (en) * 1999-10-22 2004-01-06 Antares Pharma, Inc. Medical injector and medicament loading system for use therewith
ES2332595T3 (en) * 1999-11-18 2010-02-09 Tyco Healthcare Group Lp AUTOMATIC SAFETY WRAPPING FOR NEEDLES.
GB9927715D0 (en) 1999-11-24 2000-01-19 Safe T Ltd Hollow-needle devices
JP4295821B2 (en) 1999-11-29 2009-07-15 エム ディー シー インベストメント ホールディングス インコーポレイテッド Combination of safety needle assembly and medical device
US8298150B2 (en) 2000-01-11 2012-10-30 Cedars-Sinai Medical Center Hemodynamic waveform-based diagnosis and treatment
US6970742B2 (en) 2000-01-11 2005-11-29 Savacor, Inc. Method for detecting, diagnosing, and treating cardiovascular disease
US6328699B1 (en) 2000-01-11 2001-12-11 Cedars-Sinai Medical Center Permanently implantable system and method for detecting, diagnosing and treating congestive heart failure
RU2169584C1 (en) 2000-01-17 2001-06-27 Лисовой Дмитрий Григорьевич Injector
GB0003790D0 (en) 2000-02-18 2000-04-05 Astrazeneca Uk Ltd Medical device
CA2400937C (en) 2000-02-23 2009-04-21 Abbott Laboratories Syringes and syringe systems for selectively dispensing controlled amounts of a therapeutic substance
DE10009815B4 (en) * 2000-03-01 2009-07-16 Tecpharma Licensing Ag Injection device with a needle cover
DE10009814B4 (en) 2000-03-01 2008-03-06 Tecpharma Licensing Ag Disposable injector
US6322540B1 (en) 2000-03-10 2001-11-27 International Technology Group Safe needle device for syringe
US6475194B2 (en) 2000-04-05 2002-11-05 Gem Plastics, Inc. Safety syringe
US6547763B2 (en) 2000-05-18 2003-04-15 Novo Nordisk A/S Dose display for injection device
USD461555S1 (en) 2000-05-25 2002-08-13 Jean Marc Binet Safety syringe
US6517517B1 (en) * 2000-06-08 2003-02-11 Mayo Foundation For Medical Education And Research Automated injection device for administration of liquid medicament
ES2269418T3 (en) * 2000-06-08 2007-04-01 Meridian Medical Technologies, Inc. AUTOMATIC INJECTOR ASSEMBLY FOR LIQUID / DRY MATERIAL.
US6502699B1 (en) * 2000-06-21 2003-01-07 Robert L. Watson Method and kit for making injections and withdrawing blood without the use of protective gloves
NO312059B1 (en) 2000-06-23 2002-03-11 Syringus As A cannula cover mechanism, a cannula holder and an injection syringe
EP1317296A4 (en) 2000-07-28 2004-11-17 Mdc Invest Holdings Inc Retractable needle medical device for injecting fluid from a pre-filled cartridge
US6986760B2 (en) * 2000-08-02 2006-01-17 Becton, Dickinson And Company Pen needle and safety shield system
US20060018907A1 (en) 2000-08-07 2006-01-26 Centocor, Inc. Anti-TNF antibodies and peptides of human tumor necrosis factor
UA81743C2 (en) 2000-08-07 2008-02-11 Центокор, Инк. HUMAN MONOCLONAL ANTIBODY WHICH SPECIFICALLY BINDS TUMOR NECROSIS FACTOR ALFA (TNFα), PHARMACEUTICAL MIXTURE CONTAINING THEREOF, AND METHOD FOR TREATING ARTHRITIS
US20050249735A1 (en) 2000-08-07 2005-11-10 Centocor, Inc. Methods of treating ankylosing spondylitis using anti-TNF antibodies and peptides of human tumor necrosis factor
WO2002017996A1 (en) 2000-08-29 2002-03-07 Novo Nordisk A/S Automatic injection device with torsion function for retraction of needle
US6413237B1 (en) 2000-08-31 2002-07-02 Becton, Dickinson And Company Hypodermic syringe with selectively retractable needle
JP4975208B2 (en) 2000-10-03 2012-07-11 株式会社根本杏林堂 Automatic injection equipment
US6964647B1 (en) * 2000-10-06 2005-11-15 Ellaz Babaev Nozzle for ultrasound wound treatment
US6953445B2 (en) 2000-10-10 2005-10-11 Meridian Medical Technologies, Inc. Wet/dry automatic injector assembly
FR2815543B1 (en) 2000-10-19 2003-10-24 Sedat SELF-INJECTION SYRINGE OF AN EXTEMPORANEOUS MIXTURE
US20040229854A1 (en) * 2000-11-28 2004-11-18 Pieter Haan De Immediate release dosage form for HRT
SE518981C2 (en) * 2000-12-14 2002-12-17 Shl Medical Ab autoinjector
US6387078B1 (en) * 2000-12-21 2002-05-14 Gillespie, Iii Richard D. Automatic mixing and injecting apparatus
IL156245A0 (en) * 2000-12-22 2004-01-04 Dca Design Int Ltd Drive mechanism for an injection device
AU2002256971B2 (en) 2000-12-28 2008-04-03 Altus Pharmaceuticals Inc. Crystals of whole antibodies and fragments thereof and methods for making and using them
USD453569S1 (en) 2001-01-08 2002-02-12 Pharmacia Ab Injection device
US6673049B2 (en) 2001-02-15 2004-01-06 Disetronic Licensing Ag Injection device for injecting fluid
AUPR373001A0 (en) 2001-03-14 2001-04-12 Glenord Pty Ltd Improved non-reusable syringe
BR0206160A (en) * 2001-05-25 2004-10-26 Abbott Gmbh & Co Kg Use of anti-TNF antibodies as medicines in the treatment of septic disorders of anemic patients.
CA2868614A1 (en) 2001-06-08 2002-12-08 Abbott Laboratories (Bermuda) Ltd. Methods of administering anti-tnf.alpha. antibodies
US6802827B2 (en) 2001-06-26 2004-10-12 Stig O. Andersson Hypodermic implant device
GB0118419D0 (en) 2001-07-28 2001-09-19 Owen Mumford Ltd Improvements relating to injection devices
US6782787B2 (en) * 2001-08-02 2004-08-31 Wilson Tool International, Inc. Adjustable punch having externally accessible rotation release latch
EP1281410A1 (en) * 2001-08-03 2003-02-05 Sergio Restelli Automatic safety syringe
US7163943B2 (en) * 2001-09-21 2007-01-16 Reddy Us Therapeutics, Inc. Methods and compositions of novel triazine compounds
US6494863B1 (en) 2001-10-15 2002-12-17 Retractable Technologies, Inc. One-use retracting syringe with positive needle retention
FR2830765B1 (en) * 2001-10-15 2004-07-23 Plastic Omnium Cie SAFETY DEVICE FOR A SYRINGE
JP2003122442A (en) 2001-10-16 2003-04-25 Sony Corp Wireless data communications method and apparatus for software download system
US6796967B2 (en) 2001-10-22 2004-09-28 Nps Pharmaceuticals, Inc. Injection needle assembly
US7569035B1 (en) 2001-11-02 2009-08-04 Meridian Medical Technologies, Inc. Automatic injector with anti-coring needle
AUPR867901A0 (en) 2001-11-05 2001-11-29 University of Newcastel Research Associates Limited, The 'Liquid dispenser'
US7011649B2 (en) 2001-11-09 2006-03-14 Alza Corporation Collapsible syringe cartridge
US20030105430A1 (en) 2001-11-30 2003-06-05 Elan Pharma International Limited Wil House Automatic injector
GB0200637D0 (en) 2002-01-12 2002-02-27 Dca Design Int Ltd Improvements in and relating to medicament injection apparatus
US6872194B2 (en) * 2002-01-31 2005-03-29 Safety Syringes, Inc. Disposable self-shielding syringe guard
EP1334740A1 (en) 2002-02-11 2003-08-13 Sergio Restelli Glass safety syringe and relative safety kit for glass syringe
WO2003070296A2 (en) * 2002-02-15 2003-08-28 Antares Pharma, Inc. Injector with bypass channel
US20030161828A1 (en) 2002-02-19 2003-08-28 Abbott Gmbh & Co. Kg Use of TNF antagonists as drugs for the treatment of patients with an inflammatory reaction and without suffering from total organ failure
US7033338B2 (en) 2002-02-28 2006-04-25 Smiths Medical Md, Inc. Cartridge and rod for axially loading medication pump
GB0205066D0 (en) 2002-03-05 2002-04-17 Owen Mumford Ltd Improvements relating to injection devices
WO2003077968A2 (en) 2002-03-13 2003-09-25 Eli Lilly And Company Method of treating a medical condition with a portable medication delivery device
JP2005526769A (en) * 2002-03-15 2005-09-08 ザ・ブリガーム・アンド・ウーメンズ・ホスピタル・インコーポレーテッド Central airway administration for systemic delivery of therapeutic agents
AU2003216521A1 (en) 2002-03-18 2003-10-08 Eli Lilly And Company Medication dispensing apparatus with gear set for mechanical advantage
US20030187401A1 (en) 2002-03-27 2003-10-02 Safety Syringes, Inc. Syringe with integral safety system
US6976976B2 (en) 2002-03-27 2005-12-20 Safety Syringes, Inc. Syringe with needle guard injection device
US7004929B2 (en) * 2002-03-29 2006-02-28 Mdc Investment Holdings, Inc. Safety pre-filled cartridge injector
US20030206898A1 (en) 2002-04-26 2003-11-06 Steven Fischkoff Use of anti-TNFalpha antibodies and another drug
US20040009172A1 (en) * 2002-04-26 2004-01-15 Steven Fischkoff Use of anti-TNFalpha antibodies and another drug
GB2388033A (en) 2002-05-02 2003-11-05 Pa Consulting Services Automatic injection device
BRPI0309876A2 (en) 2002-05-02 2017-03-28 Pa Knowledge Ltd injection device
US7247151B2 (en) 2002-05-09 2007-07-24 Adam Slawson Injector with shielded needle
US6808507B2 (en) 2002-05-10 2004-10-26 Cambridge Biostability Ltd. Safety injectors
US8527044B2 (en) 2002-05-15 2013-09-03 Physio-Control, Inc. User interface method and apparatus for a medical device
GB0211294D0 (en) * 2002-05-17 2002-06-26 Owen Mumford Ltd Improvements relating to injection devices
US6979316B1 (en) 2002-05-23 2005-12-27 Seedlings Life Science Ventures Llc Apparatus and method for rapid auto-injection of medication
US20050171476A1 (en) 2002-05-24 2005-08-04 Judson Jared A. Medication injecting apparatus with fluid container piston-engaging drive member having internal hollow for accommodating drive member shifting mechanism
US20030229308A1 (en) 2002-06-05 2003-12-11 Israil Tsals Injector adapter and combination thereof
GB0214452D0 (en) 2002-06-22 2002-07-31 Liversidge Barry P Medical needle assemblies
US20100160869A1 (en) 2002-06-22 2010-06-24 Barry Peter Liversidge Medical Needle Assemblies
MY139059A (en) * 2002-06-24 2009-08-28 Alza Corp Reusable, spring driven autoinjector
DE10229138B4 (en) 2002-06-28 2008-01-31 Tecpharma Licensing Ag Product diverter with piston rod emergency reset
EP3610909A1 (en) 2002-07-02 2020-02-19 PHC Holdings Corporation Automatic administration instrument for medical use
US20090280065A1 (en) 2006-04-10 2009-11-12 Willian Mary K Uses and Compositions for Treatment of Psoriasis
FR2842428B1 (en) 2002-07-19 2004-10-08 Becton Dickinson France DEVICE FOR INJECTING A PRODUCT, ESPECIALLY FOR MEDICAL USE
PT1944322E (en) 2002-07-19 2015-07-01 Abbvie Biotechnology Ltd Treatment of tnf alpha related disorders
AU2003257994A1 (en) * 2002-07-31 2004-02-16 Alza Corporation Injection device providing automatic needle retraction
US20040033228A1 (en) 2002-08-16 2004-02-19 Hans-Juergen Krause Formulation of human antibodies for treating TNF-alpha associated disorders
US20040039337A1 (en) * 2002-08-21 2004-02-26 Letzing Michael Alexander Portable safety auto-injector
EP1545661A2 (en) 2002-09-12 2005-06-29 Children's Hospital Medical Center Method and device for painless injection of medication
DK1542744T3 (en) 2002-09-24 2009-09-28 Shl Group Ab injection device
US7699816B2 (en) 2002-10-15 2010-04-20 Tecpharma Licensing Ag Injection device with priming stroke
MY150740A (en) 2002-10-24 2014-02-28 Abbvie Biotechnology Ltd Low dose methods for treating disorders in which tnf? activity is detrimental
EP1560616B1 (en) 2002-11-05 2018-01-24 Bigfoot Biomedical, Inc. A disposable wearable insulin dispensing device, a combination of such a device and a programming controller
CN100506305C (en) * 2002-11-25 2009-07-01 特克法马许可公司 Injection apparatus comprising a needle-protecting device
JP4377880B2 (en) * 2002-11-25 2009-12-02 テクファーマ・ライセンシング・アクチェンゲゼルシャフト Device for automatically injecting medication
CN100464796C (en) * 2002-11-25 2009-03-04 特克法马许可公司 Auto-injector comprising a resettable releasing safety device
GB0229345D0 (en) 2002-12-17 2003-01-22 Safe T Ltd Hollow needle applicators
GB2396816A (en) 2002-12-17 2004-07-07 Pa Consulting Services Injection device
US6767336B1 (en) 2003-01-09 2004-07-27 Sheldon Kaplan Automatic injector
WO2004067068A1 (en) 2003-01-24 2004-08-12 Alza Corporation Collapsible syringe cartridge
USD494270S1 (en) 2003-02-04 2004-08-10 Sherwood Services Ag Electrosurgical pencil with multiple scallops
US6932794B2 (en) 2003-04-03 2005-08-23 Becton, Dickinson And Company Medication delivery pen
WO2004093029A2 (en) * 2003-04-14 2004-10-28 The General Hospital Corporation Inoculation training kit
US6805686B1 (en) 2003-05-06 2004-10-19 Abbott Laboratories Autoinjector with extendable needle protector shroud
US6926697B2 (en) 2003-05-13 2005-08-09 Robert Malenchek Adaptor for converting a non-safety syringe into a safety syringe
GB0315600D0 (en) * 2003-07-04 2003-08-13 Owen Mumford Ltd Improvements relating to automatic injection devices
US7500963B2 (en) * 2003-07-22 2009-03-10 Safety Syringes, Inc. Systems and methods for automatic medical injection with safeguard
KR100513274B1 (en) 2003-07-30 2005-09-09 이디텍 주식회사 A controlling method for a high speed DVI using compression technique and a DVI transmitter and Receiver using the method
US20050027255A1 (en) * 2003-07-31 2005-02-03 Sid Technologies, Llc Automatic injector
EP1502613A1 (en) * 2003-08-01 2005-02-02 Novo Nordisk A/S Needle device with retraction means
DE10339794A1 (en) * 2003-08-28 2005-04-07 Tecpharma Licensing Ag Administering device with a protective cap removal device and a needle protection sleeve blocking device
DE10340586A1 (en) * 2003-09-03 2005-04-07 Tecpharma Licensing Ag Mixing device for multi-chamber ampoule
FR2860162B1 (en) 2003-09-26 2006-06-02 Becton Dickinson France DEVICE FOR PROTECTING AN INJECTION APPARATUS
GB0406458D0 (en) 2003-10-09 2004-04-28 Liversidge Barry P Safety medical needle assemblies
US20050085776A1 (en) 2003-10-16 2005-04-21 Edgar Hommann Injection device for administering a fluid product
USD518175S1 (en) * 2003-10-31 2006-03-28 Wilson-Cook Medical Inc. Handle for medical devices, and medical device assemblies using a handle
US9554984B2 (en) * 2003-11-03 2017-01-31 Jaleva Pharmaceuticals, Llc Oral care compositions for topical application
US7497847B2 (en) 2003-11-03 2009-03-03 Becton, Dickinson And Company Safety shield system for a syringe
US20050096597A1 (en) 2003-11-03 2005-05-05 Becton, Dickinson And Company Safety shield system for a syringe
US7635348B2 (en) 2003-11-04 2009-12-22 Meridian Medical Technologies, Inc. Container for medicament automatic injector and automatic injector adapted therefor
CA2511746C (en) 2003-11-06 2013-03-26 Lifescan, Inc. Drug delivery pen with event notification means
US20050101919A1 (en) 2003-11-07 2005-05-12 Lennart Brunnberg Device for an injector
CH696421A5 (en) 2003-12-18 2007-06-15 Tecpharma Licensing Ag Autoinjector with arresting the drug container.
GB2410188B (en) 2004-01-23 2006-01-25 Medical House Plc Injection device
KR101131099B1 (en) 2004-01-23 2012-04-24 더 메디컬 하우스 피엘씨 Injection device
GB0403335D0 (en) 2004-02-14 2004-03-17 Liversidge Barry P Medical injector handling device
ITTO20040169A1 (en) 2004-03-15 2004-06-15 Teksid Aluminum S R L SEALING SYSTEM FOR HIGH PRESSURE AND HIGH TEMPERATURE CONTAINERS
US20050222539A1 (en) 2004-03-30 2005-10-06 Pediamed Pharmaceuticals, Inc. Automatic injection device
NZ549099A (en) 2004-03-30 2010-05-28 Lilly Co Eli Medication dispensing apparatus with spring-driven locking feature enabled by administration of final dose
WO2005097239A1 (en) * 2004-03-31 2005-10-20 Cook Incorporated Apparatus for an improved high pressure medicinal dispenser
TWI439284B (en) * 2004-04-09 2014-06-01 Abbvie Biotechnology Ltd Multiple-variable dose regimen for treating tnfα-related disorders
DE602004020277D1 (en) 2004-04-29 2009-05-07 Abbott Lab AUTO INJECTOR WITH EXTENDABLE NEEDLE PROTECTION COVER
GB2414400B (en) 2004-05-28 2009-01-14 Cilag Ag Int Injection device
GB2414399B (en) 2004-05-28 2008-12-31 Cilag Ag Int Injection device
GB2414406B (en) 2004-05-28 2009-03-18 Cilag Ag Int Injection device
GB2414405B (en) 2004-05-28 2009-01-14 Cilag Ag Int Injection device
GB2414402B (en) * 2004-05-28 2009-04-22 Cilag Ag Int Injection device
GB2414404B (en) 2004-05-28 2009-06-03 Cilag Ag Int Injection device
GB2414403B (en) 2004-05-28 2009-01-07 Cilag Ag Int Injection device
US20050273054A1 (en) 2004-06-03 2005-12-08 Florida Atlantic University Epinephrine auto-injector
GB0414054D0 (en) * 2004-06-23 2004-07-28 Owen Mumford Ltd Improvements relating to automatic injection devices
EP1791583A4 (en) 2004-07-16 2016-08-17 Unitract Syringe Pty Ltd Syringe needle sheath
US20060100588A1 (en) 2004-07-23 2006-05-11 Lennart Brunnberg Needle handling device
US7449012B2 (en) * 2004-08-06 2008-11-11 Meridian Medical Technologies, Inc. Automatic injector
US20060074519A1 (en) 2004-08-27 2006-04-06 Barker Kenneth N Medication accuracy comparison system
US20060047250A1 (en) * 2004-08-30 2006-03-02 Hickingbotham Dyson W Fluid delivery device
DE102004042581B4 (en) 2004-09-02 2022-09-15 Ypsomed Ag Auto-Pen for dual-chamber ampoule
US20060069354A1 (en) * 2004-09-30 2006-03-30 Buenger David R Syringe activation device
US20060069350A1 (en) * 2004-09-30 2006-03-30 Buenger David R Medical syringe injector pen
US20060083741A1 (en) 2004-10-08 2006-04-20 Hoffman Rebecca S Treatment of respiratory syncytial virus (RSV) infection
US20060089540A1 (en) 2004-10-27 2006-04-27 Alan Meissner Device for diabetes management
US20060178865A1 (en) 2004-10-29 2006-08-10 Edwards D Craig Multilingual user interface for a medical device
JP4960252B2 (en) 2004-11-22 2012-06-27 インテリジェクト，インコーポレイテッド Device, system and method for drug delivery
US7947017B2 (en) 2004-11-22 2011-05-24 Intelliject, Inc. Devices, systems and methods for medicament delivery
US7648483B2 (en) 2004-11-22 2010-01-19 Intelliject, Inc. Devices, systems and methods for medicament delivery
US7648482B2 (en) 2004-11-22 2010-01-19 Intelliject, Inc. Devices, systems, and methods for medicament delivery
ES2412332T3 (en) 2004-11-24 2013-07-11 Becton, Dickinson And Company Automatic reconstitution injector device
US20060129122A1 (en) 2004-12-06 2006-06-15 Wyrick Ronald E Method and apparatus for delivering epinephrine
US7905352B2 (en) 2004-12-06 2011-03-15 Washington Biotech Corporation Kits containing medicine injection devices and containers
JP2008522754A (en) * 2004-12-09 2008-07-03 ウェスト ファーマシューティカル サービシズ インコーポレイテッド Retrofit type fixed needle syringe and automatic injection apparatus having the same
US7731686B2 (en) 2005-02-01 2010-06-08 Intelliject, Inc. Devices, systems and methods for medicament delivery
US8231573B2 (en) 2005-02-01 2012-07-31 Intelliject, Inc. Medicament delivery device having an electronic circuit system
JP4948422B2 (en) 2005-02-01 2012-06-06 インテリジェクト，インコーポレイテッド Drug delivery apparatus, system and method
US9022980B2 (en) 2005-02-01 2015-05-05 Kaleo, Inc. Medical injector simulation device
US8206360B2 (en) 2005-02-01 2012-06-26 Intelliject, Inc. Devices, systems and methods for medicament delivery
US8361026B2 (en) 2005-02-01 2013-01-29 Intelliject, Inc. Apparatus and methods for self-administration of vaccines and other medicaments
US8226610B2 (en) 2005-02-01 2012-07-24 Intelliject, Inc. Medical injector with compliance tracking and monitoring
US8062252B2 (en) 2005-02-18 2011-11-22 Becton, Dickinson And Company Safety shield system for a syringe
US20090240210A1 (en) 2005-03-14 2009-09-24 Global Medisafe Holdings Limited Auto retractable syringe
USD545439S1 (en) 2005-04-15 2007-06-26 Becton, Dickinson And Company Blood glucose meter
FR2884723B1 (en) * 2005-04-20 2008-03-14 Becton Dickinson France Soc Pa DEVICE FOR PROTECTING AN INJECTION DEVICE
CN100544784C (en) 2005-04-26 2009-09-30 刘文杰 The barrel type push bar of needle retraction type syringe and needle retractable controllable type syringe
US7694828B2 (en) * 2005-04-27 2010-04-13 Biomet Manufacturing Corp. Method and apparatus for producing autologous clotting components
US7905868B2 (en) * 2006-08-23 2011-03-15 Medtronic Minimed, Inc. Infusion medium delivery device and method with drive device for driving plunger in reservoir
NZ627177A (en) 2005-05-16 2016-02-26 Abbvie Biotechnology Ltd Use of tnf inhibitor for treatment of erosive polyarthritis
JP2008543500A (en) * 2005-06-21 2008-12-04 イーライ リリー アンド カンパニー Instruments and methods for pharmaceutical injection
US20070041905A1 (en) * 2005-08-19 2007-02-22 Hoffman Rebecca S Method of treating depression using a TNF-alpha antibody
CN101282752A (en) 2005-10-11 2008-10-08 伊莱利利公司 Apparatus for injecting a pharmaceutical
BRPI0618085A2 (en) 2005-11-01 2011-08-16 Abbott Biotech Ltd Processes and kits for diagnosis of ankylosing spondylitis using biomarkers
US7682155B2 (en) 2005-11-03 2010-03-23 Meridian Medical Technologies, Inc. Training device for an automatic injector
US20070161960A1 (en) 2006-01-12 2007-07-12 Fu-Yuan Li Lancet device
US8496627B2 (en) 2006-03-21 2013-07-30 Covidien Lp Passive latch ring safety shield for injection devices
GB2477046B (en) 2006-03-29 2011-08-24 Intelliject Inc Devices,systems and methods for medicament delivery
NZ596517A (en) * 2006-04-05 2013-06-28 Abbott Biotech Ltd Antibody purification
EP2007426A4 (en) * 2006-04-10 2010-06-16 Abbott Biotech Ltd Uses and compositions for treatment of psoriatic arthritis
US9399061B2 (en) 2006-04-10 2016-07-26 Abbvie Biotechnology Ltd Methods for determining efficacy of TNF-α inhibitors for treatment of rheumatoid arthritis
US9605064B2 (en) 2006-04-10 2017-03-28 Abbvie Biotechnology Ltd Methods and compositions for treatment of skin disorders
US20080118496A1 (en) 2006-04-10 2008-05-22 Medich John R Uses and compositions for treatment of juvenile rheumatoid arthritis
EP2012586A4 (en) 2006-04-10 2010-08-18 Abbott Biotech Ltd Uses and compositions for treatment of ankylosing spondylitis
US20090317399A1 (en) 2006-04-10 2009-12-24 Pollack Paul F Uses and compositions for treatment of CROHN'S disease
US20080131374A1 (en) 2006-04-19 2008-06-05 Medich John R Uses and compositions for treatment of rheumatoid arthritis
WO2007131013A1 (en) 2006-05-03 2007-11-15 Antares Pharma, Inc. Two-stage reconstituting injector
GB2465919B (en) 2006-05-10 2010-12-08 Owen Mumford Ltd Injection device with cap that can be re-fitted post injection
US20080311043A1 (en) 2006-06-08 2008-12-18 Hoffman Rebecca S Uses and compositions for treatment of psoriatic arthritis
US20100021451A1 (en) * 2006-06-08 2010-01-28 Wong Robert L Uses and compositions for treatment of ankylosing spondylitis
AU2007269791B2 (en) 2006-06-30 2013-10-03 Abbvie Biotechnology Ltd Automatic injection device
WO2008006118A2 (en) * 2006-07-07 2008-01-10 Bioassets Development Corporation Novel regimens for treating diseases and disorders
DE102006038101A1 (en) 2006-08-14 2008-02-21 Tecpharma Licensing Ag Injection device with jaw safety
USD629509S1 (en) 2006-09-06 2010-12-21 Abbott Biotechnology Ltd. Automatic injection device
USD622374S1 (en) 2006-09-06 2010-08-24 Abbott Biotechnology Ltd. Automatic injection device
SG174804A1 (en) 2006-09-13 2011-10-28 Abbott Lab
CN100563740C (en) 2006-09-28 2009-12-02 明辰股份有限公司 Safe medicament injection apparatus for medical and be used for the push bar assembly of medical medicine injection
CA2667655A1 (en) * 2006-10-27 2008-05-15 Abbott Biotechnology Ltd. Crystalline anti-htnfalpha antibodies
DK2099434T3 (en) 2006-11-21 2019-08-12 Kaleo Inc DEVICES AND SYSTEMS FOR MEDICINAL ADMINISTRATION
JP5014835B2 (en) 2007-02-28 2012-08-29 株式会社山越 Rainwater infiltration dredging and rainwater infiltration hatching method for existing rainwater dredging
EP2679996A1 (en) * 2007-05-31 2014-01-01 AbbVie Inc. Biomarkers predictive of the responsiveness to TNF-alfa inhibitors in autoimmune disorders
US9044378B2 (en) 2007-05-31 2015-06-02 Safety Syringes, Inc. Anti-needle stick safety device or system for use with drugs requiring reconstitution
EP2152318A4 (en) * 2007-06-01 2011-12-07 Abbott Biotech Ltd Uses and compositions for treatment of psoriasis and crohn's disease
US8999337B2 (en) 2007-06-11 2015-04-07 Abbvie Biotechnology Ltd. Methods for treating juvenile idiopathic arthritis by inhibition of TNFα
EP2173380A4 (en) 2007-07-13 2011-08-31 Abbott Biotech Ltd METHODS AND COMPOSITIONS FOR PULMONARY ADMINISTRATION OF A TNFa INHIBITOR
MX2010001488A (en) 2007-08-08 2010-03-01 Abbott Lab Compositions and methods for crystallizing antibodies.
ES2742504T3 (en) 2007-09-25 2020-02-14 Becton Dickinson France Autoinjector with shield elimination element comprising anti-tamper means
EP2195052B1 (en) 2007-10-02 2019-09-04 Medimop Medical Projects Ltd. External drug pump
USD619702S1 (en) 2007-11-15 2010-07-13 Tecpharma Licensing Ag Medicine injector
MX354100B (en) 2007-11-30 2018-02-13 Abbvie Biotechnology Ltd Star Protein formulations and methods of making same.
US20090157012A1 (en) 2007-12-13 2009-06-18 University Of Victoria Innovation And Development Corporation Syringe with extendable and retractable needle
WO2009086550A1 (en) 2008-01-03 2009-07-09 Abbott Laboratories Predicting long-term efficacy of a compound in the treatment of psoriasis
KR101521319B1 (en) 2008-01-11 2015-05-18 유씨비 파마, 에스.에이. Systems for administering medication for rheumatoid arthritis patients
CA2711984A1 (en) 2008-01-15 2009-07-23 Abbott Gmbh & Co. Kg Powdered protein compositions and methods of making same
ES2579231T3 (en) 2008-01-15 2016-08-08 Abbvie Inc Enhanced mammalian expression vectors and uses thereof
CA2717905A1 (en) * 2008-03-24 2009-10-01 Abbott Biotechnology Ltd. Methods and compositions for treating bone loss
US8021344B2 (en) 2008-07-28 2011-09-20 Intelliject, Inc. Medicament delivery device configured to produce an audible output
WO2009140251A2 (en) 2008-05-12 2009-11-19 Intelliject, Inc. Medicament delivery device having an electronic circuit system
AU2009262896B2 (en) 2008-05-30 2015-04-02 Allergan, Inc. Injection device for soft-tissue augmentation fillers, bioactive agents and other biocompatible materials in liquid or gel form
US8069097B2 (en) 2008-06-05 2011-11-29 Harris Corporation Media inventory service
CN102065938B (en) 2008-06-20 2014-09-03 西部制药服务公司 Automatic injection mechanism with frontal buttress
JP5161712B2 (en) 2008-09-03 2013-03-13 キヤノン株式会社 Imaging apparatus and imaging method
CA2734035C (en) 2008-09-10 2014-05-06 F. Hoffmann-La Roche Ag Delivery device for use with a therapeutic drug
USD641077S1 (en) 2008-09-15 2011-07-05 Sanofi-Aventis Deutschland Gmbh Medical injector
EP2180459A1 (en) 2008-10-24 2010-04-28 Sanofi-Aventis Deutschland GmbH Device for simulating the operation of a medication delivery device
GB2465389A (en) 2008-11-17 2010-05-19 Owen Mumford Ltd Syringe needle cover remover
USD621932S1 (en) 2009-03-23 2010-08-17 Karl Storz Gmbh & Co. Kg Videolaparoscope
USD655060S1 (en) 2009-03-23 2012-02-28 Karl Storz Gmbh & Co. Kg Cleaning adapter
MX2011011541A (en) 2009-04-29 2012-02-28 Abbott Biotech Ltd Automatic injection device.
CN104490767A (en) 2009-05-04 2015-04-08 艾伯维生物技术有限公司 Stable High Protein Concentration Formulations Of Human Anti-tnf-alpha-antibodies
DK3184138T3 (en) 2009-05-26 2023-05-15 Shl Medical Ag NEEDLE HOUSING ASSEMBLY
CA2769030C (en) 2009-07-30 2016-05-10 Tandem Diabetes Care, Inc. Infusion pump system with disposable cartridge having pressure venting and pressure feedback
CN102497909B (en) 2009-07-31 2014-10-29 3M创新有限公司 Hollow microneedle arrays
USD633199S1 (en) 2009-10-05 2011-02-22 Pyng Medical Corp. Insertion tool for bone portals
NZ627052A (en) 2009-12-15 2015-12-24 Abbvie Biotechnology Ltd Improved firing button for automatic injection device
EP2361648A1 (en) 2010-02-18 2011-08-31 Sanofi-Aventis Deutschland GmbH Remover for a protective needle shield
USD645139S1 (en) 2010-05-11 2011-09-13 Discus Dental, Llc Dental composite syringe
PT2575884T (en) 2010-06-03 2018-10-31 Abbvie Biotechnology Ltd Uses and compositions for treatment of hidradenitis suppurativa (hs)
USD638935S1 (en) 2010-06-25 2011-05-31 Abbott Cardiovascular Systems Inc. Medical device handle
USD650070S1 (en) 2010-09-16 2011-12-06 Panasonic Corporation Injector
USD647613S1 (en) 2010-12-30 2011-10-25 Kimberly-Clark, Inc. Ergonomic handle for medical device
WO2012103141A1 (en) 2011-01-24 2012-08-02 Abbott Biotechnology Ltd. Automatic injection devices having overmolded gripping surfaces
ES2859511T3 (en) 2011-01-24 2021-10-04 Abbvie Biotechnology Ltd Removal of needle guards from syringes and automatic injection devices
AU2012210170B2 (en) 2011-01-24 2016-09-29 Elcam Medical Agricultural Cooperative Association Ltd. Injector
USD677380S1 (en) 2011-01-24 2013-03-05 Abbvie Biotechnology Ltd. Automatic injection device
AU2012231178B2 (en) 2011-03-18 2015-11-05 Abbvie Inc. Systems, devices and methods for assembling automatic injection devices and sub-assemblies thereof
EP3020428A1 (en) 2011-04-21 2016-05-18 AbbVie Inc. Wearable automatic injection device for controlled administration of therapeutic agents
USD653329S1 (en) 2011-05-11 2012-01-31 Femasys Inc. Device for relieving fluid pressure
MX347426B (en) 2012-03-02 2017-04-26 Abbvie Inc Automatic injection training device.

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9333309B2 (en) 2002-02-11 2016-05-10 Antares Pharma, Inc. Intradermal injector
US9180259B2 (en) 2005-01-24 2015-11-10 Antares Pharma, Inc. Prefilled syringe jet injector
US9144648B2 (en) 2006-05-03 2015-09-29 Antares Pharma, Inc. Injector with adjustable dosing
US9561333B2 (en) 2008-08-05 2017-02-07 Antares Pharma, Inc. Multiple dosage injector
US8945063B2 (en) 2009-03-20 2015-02-03 Antares Pharma, Inc. Hazardous agent injection system
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US9446195B2 (en) 2011-07-15 2016-09-20 Antares Pharma, Inc. Injection device with cammed ram assembly
US9486583B2 (en) 2012-03-06 2016-11-08 Antares Pharma, Inc. Prefilled syringe with breakaway force feature
US9364610B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Injection device with cammed ram assembly
US9364611B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US9393367B2 (en) 2013-03-12 2016-07-19 Antares Pharma, Inc. Prefilled syringes and kits thereof

Also Published As

Publication number Publication date
CN103316403A (en) 2013-09-25
BRPI0713802A2 (en) 2012-11-06
WO2008005315A3 (en) 2008-11-13
KR20090025305A (en) 2009-03-10
US9486584B2 (en) 2016-11-08
CN107243099A (en) 2017-10-13
IL221301A (en) 2015-07-30
IL244058A0 (en) 2016-04-21
US20170203041A1 (en) 2017-07-20
CN101484199B (en) 2014-06-25
TWI527603B (en) 2016-04-01
US20100160894A1 (en) 2010-06-24
WO2008005315A2 (en) 2008-01-10
JP2015142747A (en) 2015-08-06
CN103316403B (en) 2017-05-24
TWI542374B (en) 2016-07-21
TW201406419A (en) 2014-02-16
AU2007269791B2 (en) 2013-10-03
IL195235A (en) 2014-05-28
SG173339A1 (en) 2011-08-29
JP5913422B2 (en) 2016-05-11
CN101484199A (en) 2009-07-15
CA2651992A1 (en) 2008-01-10
NZ608925A (en) 2014-10-31
JP6133949B2 (en) 2017-05-24
NZ595605A (en) 2013-05-31
RU2011137704A (en) 2013-03-20
IL215312A (en) 2015-05-31
TW201406420A (en) 2014-02-16
US20160089495A1 (en) 2016-03-31
IL221300A (en) 2016-02-29
EP2043711A4 (en) 2017-08-30
TWI498137B (en) 2015-09-01
AU2007269791A1 (en) 2008-01-10
CN103316402A (en) 2013-09-25
KR101440795B1 (en) 2014-09-22
KR101396797B1 (en) 2014-05-26
US20150037772A1 (en) 2015-02-05
ZA201006269B (en) 2019-06-26
JP2017185255A (en) 2017-10-12
IL195235A0 (en) 2009-08-03
EP2043711A2 (en) 2009-04-08
RU2015135983A (en) 2017-03-03
WO2008005315A9 (en) 2008-03-13
JP5758860B2 (en) 2015-08-05
ZA200810349B (en) 2010-11-24
US8679061B2 (en) 2014-03-25
JP2009542334A (en) 2009-12-03
MX2008016335A (en) 2009-01-21
KR20120112503A (en) 2012-10-11
JP5535623B2 (en) 2014-07-02
JP2014208026A (en) 2014-11-06
JP2013034869A (en) 2013-02-21
US9572938B2 (en) 2017-02-21
JP2016039906A (en) 2016-03-24
US20120107783A1 (en) 2012-05-03
IL215312A0 (en) 2011-11-30
TW200819154A (en) 2008-05-01
NZ572765A (en) 2012-08-31

Similar Documents

Publication Publication Date Title
WO2008005315A8 (en) Automatic injection device
WO2008021706A3 (en) Injection system with hidden needles
EP2340863A3 (en) Substance delivery device
NZ590615A (en) Re-useable auto-injector with filling means and method of priming the device
MX2008005782A (en) Fluid delivery devices, systems and methods.
MX2010004542A (en) Implant delivery device and method.
MY152872A (en) Extraction system for the preparation of a beverage from a cartridge
NZ590611A (en) Re-useable auto-injector and method of priming the device
NZ593137A (en) Auto-injector apparatus with a pump for engaging with a flexible medicament container to expel the medicament
MX2009013562A (en) Syringe infusion pump.
PT1931407E (en) Single use safety syringe having a retractable needle
WO2005069831A3 (en) Injector for viscous materials
ATE516834T1 (en) ADMINISTRATION DEVICE WITH FUNCTIONAL DRIVE ELEMENT
MX345765B (en) Improvements relating to automatic injection devices.
WO2006113474A3 (en) Corneal implant injector assembly and methods of use
HUE047397T2 (en) Syringes, syringe interfaces and syringe plungers for use with medical injectors
EP1917991A4 (en) Plunger for injector, and syringe and prefilled syringe that use the same
TW200743500A (en) Disposable syringe
TWI256900B (en) Syringe with withdrawal force
GB2430628A (en) Disposable syringe
WO2009013011A3 (en) Injection device for injection into biological tissue, and injection depot
EP3834865A3 (en) Reusable automatic injection device
ATE349236T1 (en) DEVICE FOR INJECTING AN INJECTABLE PRODUCT
WO2007127859A3 (en) Apparatus for refilling an infusion device
ATE460198T1 (en) SHARP CONTAINER FOR CONTACTLESS SEQUENTIAL SAFE STORAGE OF USED PEN NEEDLES

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200780024818.5

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07810031

Country of ref document: EP

Kind code of ref document: A2

DPE2 Request for preliminary examination filed before expiration of 19th month from priority date (pct application filed from 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2651992

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2007269791

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 9978/DELNP/2008

Country of ref document: IN

ENP Entry into the national phase

Ref document number: 2007269791

Country of ref document: AU

Date of ref document: 20070629

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: MX/A/2008/016335

Country of ref document: MX

WWE Wipo information: entry into national phase

Ref document number: 2009518284

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 1020087032140

Country of ref document: KR

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2007810031

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2009102986

Country of ref document: RU

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 1020127017120

Country of ref document: KR

WWE Wipo information: entry into national phase

Ref document number: 221300

Country of ref document: IL

Ref document number: 221301

Country of ref document: IL

ENP Entry into the national phase

Ref document number: PI0713802

Country of ref document: BR

Kind code of ref document: A2

Effective date: 20081226

DPE2 Request for preliminary examination filed before expiration of 19th month from priority date (pct application filed from 20040101)
WWE Wipo information: entry into national phase

Ref document number: 244058

Country of ref document: IL