WO2007146001A3 - Coatings for implantable medical devices for controlled release of a hydrophilic drug and a hydrophobic drug - Google Patents

Coatings for implantable medical devices for controlled release of a hydrophilic drug and a hydrophobic drug Download PDF

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Publication number
WO2007146001A3
WO2007146001A3 PCT/US2007/013327 US2007013327W WO2007146001A3 WO 2007146001 A3 WO2007146001 A3 WO 2007146001A3 US 2007013327 W US2007013327 W US 2007013327W WO 2007146001 A3 WO2007146001 A3 WO 2007146001A3
Authority
WO
WIPO (PCT)
Prior art keywords
drug
coatings
controlled release
medical devices
implantable medical
Prior art date
Application number
PCT/US2007/013327
Other languages
French (fr)
Other versions
WO2007146001A2 (en
Inventor
Thierry Glauser
Irina Astafieva
Syed Faiyaz Ahmed Hossainy
Original Assignee
Abbott Cardiovascular Systems
Thierry Glauser
Irina Astafieva
Syed Faiyaz Ahmed Hossainy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Cardiovascular Systems, Thierry Glauser, Irina Astafieva, Syed Faiyaz Ahmed Hossainy filed Critical Abbott Cardiovascular Systems
Publication of WO2007146001A2 publication Critical patent/WO2007146001A2/en
Publication of WO2007146001A3 publication Critical patent/WO2007146001A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/25—Peptides having up to 20 amino acids in a defined sequence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow

Abstract

Provided herein is a coating that includes cRGD for endothelial cells and methods of making and using the same.
PCT/US2007/013327 2006-06-05 2007-06-05 Coatings for implantable medical devices for controlled release of a hydrophilic drug and a hydrophobic drug WO2007146001A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/447,551 US8703167B2 (en) 2006-06-05 2006-06-05 Coatings for implantable medical devices for controlled release of a hydrophilic drug and a hydrophobic drug
US11/447,551 2006-06-05

Publications (2)

Publication Number Publication Date
WO2007146001A2 WO2007146001A2 (en) 2007-12-21
WO2007146001A3 true WO2007146001A3 (en) 2008-02-07

Family

ID=38669207

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/013327 WO2007146001A2 (en) 2006-06-05 2007-06-05 Coatings for implantable medical devices for controlled release of a hydrophilic drug and a hydrophobic drug

Country Status (2)

Country Link
US (1) US8703167B2 (en)
WO (1) WO2007146001A2 (en)

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US8703167B2 (en) 2006-06-05 2014-04-22 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices for controlled release of a hydrophilic drug and a hydrophobic drug
US20090258028A1 (en) * 2006-06-05 2009-10-15 Abbott Cardiovascular Systems Inc. Methods Of Forming Coatings For Implantable Medical Devices For Controlled Release Of A Peptide And A Hydrophobic Drug
US8323676B2 (en) 2008-06-30 2012-12-04 Abbott Cardiovascular Systems Inc. Poly(ester-amide) and poly(amide) coatings for implantable medical devices for controlled release of a protein or peptide and a hydrophobic drug
US20080102123A1 (en) * 2006-10-27 2008-05-01 Schachter Deborah M Self-gelling tunable drug delivery system
US8679519B2 (en) * 2007-10-23 2014-03-25 Abbott Cardiovascular Systems Inc. Coating designs for the tailored release of dual drugs from polymeric coatings
US20090192583A1 (en) * 2008-01-28 2009-07-30 Medtronic Vascular, Inc. Ordered Coatings for Drug Eluting Stents and Medical Devices
EP2095832A1 (en) * 2008-02-28 2009-09-02 Bayer MaterialScience AG Post-operative adhesion barriers
US20090240323A1 (en) * 2008-03-20 2009-09-24 Medtronic Vascular, Inc. Controlled Degradation of Magnesium Stents
US8765162B2 (en) 2008-06-30 2014-07-01 Abbott Cardiovascular Systems Inc. Poly(amide) and poly(ester-amide) polymers and drug delivery particles and coatings containing same
ES2630805T3 (en) 2008-07-14 2017-08-24 Polypid Ltd. Sustained release drug vehicle composition
US20100047319A1 (en) * 2008-08-21 2010-02-25 Michael Huy Ngo Biodegradable Poly(Ester-Amide) And Poly(Amide) Coatings For Implantable Medical Devices With Enhanced Bioabsorption Times
US8092822B2 (en) * 2008-09-29 2012-01-10 Abbott Cardiovascular Systems Inc. Coatings including dexamethasone derivatives and analogs and olimus drugs
US20100094407A1 (en) * 2008-10-10 2010-04-15 Medtronic Vascular, Inc. Multiple Bioactive Agent Eluting Stents
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EP2452653B1 (en) 2010-11-12 2013-11-27 Biotronik AG cRGD peptide derivative and its manufacture and implant having a coating containing a cRGD peptide derivative
EP2452702B1 (en) * 2010-11-12 2015-03-04 Biotronik AG Functionalized RGD peptidomimetics and their manufacture, and implant having a coating containing such functionalized RGD peptidomimetics
US8961592B2 (en) 2010-11-12 2015-02-24 Biotronik Ag Functionalized RGD peptidomimetics and their manufacture, and implant having a coating containing such functional-ized RGD peptidomimetics
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US20140271861A1 (en) * 2011-07-27 2014-09-18 Polypid Ltd. Matrix compositions for controlled release of peptide and polypeptide molecules
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CN102964593B (en) * 2012-12-17 2015-02-18 中国科学院长春应用化学研究所 Block polymer, preparation method thereof and electrically active hydrogel
CA3062314C (en) 2017-05-04 2023-10-10 Hollister Incorporated Lubricious hydrophilic coatings and methods of forming the same
CN113786492B (en) * 2021-08-13 2023-03-28 四川大学华西医院 Polymer carrier for photodynamic therapy and preparation method and application thereof
CN113797350B (en) * 2021-08-13 2023-05-05 四川大学华西医院 Glycosyl polymer and preparation method and application thereof
WO2023126965A1 (en) * 2022-01-02 2023-07-06 Nano Therapeutics Private Limited Directional and temporal release of drugs from medical devices

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