WO2007125354A3 - Mass spectrometer - Google Patents

Mass spectrometer Download PDF

Info

Publication number
WO2007125354A3
WO2007125354A3 PCT/GB2007/001589 GB2007001589W WO2007125354A3 WO 2007125354 A3 WO2007125354 A3 WO 2007125354A3 GB 2007001589 W GB2007001589 W GB 2007001589W WO 2007125354 A3 WO2007125354 A3 WO 2007125354A3
Authority
WO
WIPO (PCT)
Prior art keywords
mass analyser
mass
ion guide
ion
ions
Prior art date
Application number
PCT/GB2007/001589
Other languages
French (fr)
Other versions
WO2007125354A2 (en
Inventor
Martin Green
Jason Lee Wildgoose
Steven Derek Pringle
Daniel James Kenny
Original Assignee
Micromass Ltd
Martin Green
Jason Lee Wildgoose
Steven Derek Pringle
Daniel James Kenny
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0608470.1A external-priority patent/GB0608470D0/en
Priority to JP2009507174A priority Critical patent/JP5290960B2/en
Priority to US12/297,481 priority patent/US7919747B2/en
Priority to EP07732622.1A priority patent/EP2013895B8/en
Priority to CA2650390A priority patent/CA2650390C/en
Priority to CN200780024103XA priority patent/CN101479828B/en
Application filed by Micromass Ltd, Martin Green, Jason Lee Wildgoose, Steven Derek Pringle, Daniel James Kenny filed Critical Micromass Ltd
Publication of WO2007125354A2 publication Critical patent/WO2007125354A2/en
Publication of WO2007125354A3 publication Critical patent/WO2007125354A3/en
Priority to HK09112043.3A priority patent/HK1132839A1/en
Priority to US13/078,198 priority patent/US8455819B2/en
Priority to US13/908,568 priority patent/US8586917B2/en
Priority to US14/081,201 priority patent/US9269549B2/en
Priority to US15/042,245 priority patent/US9786479B2/en

Links

Classifications

    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • H01J49/34Dynamic spectrometers
    • H01J49/42Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205Device types
    • H01J49/422Two-dimensional RF ion traps
    • H01J49/4235Stacked rings or stacked plates
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/06Electron- or ion-optical arrangements
    • H01J49/062Ion guides
    • H01J49/065Ion guides having stacked electrodes, e.g. ring stack, plate stack

Abstract

An ion guide or mass analyser (2) is disclosed comprising a plurality of electrodes (2a) having apertures through which ions are transmitted in use. A pseudo-potential barrier is created at the exit of the ion guide or mass analyser (2). The amplitude or depth of the pseudo-potential barrier is inversely proportional to the mass to charge ratio of an ion. One or more transient DC voltages (4) are applied to the electrodes (2a) of the ion guide or mass analyser (2) in order to urge ions along the length of the ion guides or mass analyser (2). The amplitude of the transient DC voltage (4) applied to the electrode (2a) may be increased with time so that ions are caused to be emitted from the ion guide or mass analyser (2) in reverse order of their mass to charge ratio.
PCT/GB2007/001589 2006-04-28 2007-04-30 Mass spectrometer WO2007125354A2 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP2009507174A JP5290960B2 (en) 2006-04-28 2007-04-30 Mass spectrometer
US12/297,481 US7919747B2 (en) 2006-04-28 2007-04-30 Mass spectrometer
EP07732622.1A EP2013895B8 (en) 2006-04-28 2007-04-30 Mass spectrometer
CA2650390A CA2650390C (en) 2006-04-28 2007-04-30 Mass spectrometer
CN200780024103XA CN101479828B (en) 2006-04-28 2007-04-30 Mass spectrometer
HK09112043.3A HK1132839A1 (en) 2006-04-28 2009-12-22 Mass to charge ratio selective barrier
US13/078,198 US8455819B2 (en) 2006-04-28 2011-04-01 Mass spectrometer device and method using scanned phase applied potentials in ion guidance
US13/908,568 US8586917B2 (en) 2006-04-28 2013-06-03 Mass spectrometer device and method using scanned phase applied potentials in ion guidance
US14/081,201 US9269549B2 (en) 2006-04-28 2013-11-15 Mass spectrometer device and method using scanned phase applied potentials in ion guidance
US15/042,245 US9786479B2 (en) 2006-04-28 2016-02-12 Mass spectrometer device and method using scanned phase applied potentials in ion guidance

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0608470.1 2006-04-28
GBGB0608470.1A GB0608470D0 (en) 2006-04-28 2006-04-28 Mass spectrometer
US80177206P 2006-05-19 2006-05-19
US60/801,772 2006-05-19

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US12/297,481 A-371-Of-International US7919747B2 (en) 2006-04-28 2007-04-30 Mass spectrometer
US13/078,198 Continuation US8455819B2 (en) 2006-04-28 2011-04-01 Mass spectrometer device and method using scanned phase applied potentials in ion guidance

Publications (2)

Publication Number Publication Date
WO2007125354A2 WO2007125354A2 (en) 2007-11-08
WO2007125354A3 true WO2007125354A3 (en) 2008-10-02

Family

ID=38573479

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2007/001589 WO2007125354A2 (en) 2006-04-28 2007-04-30 Mass spectrometer

Country Status (5)

Country Link
EP (1) EP2013895B8 (en)
JP (1) JP5290960B2 (en)
CA (1) CA2650390C (en)
HK (1) HK1132839A1 (en)
WO (1) WO2007125354A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0514964D0 (en) 2005-07-21 2005-08-24 Ms Horizons Ltd Mass spectrometer devices & methods of performing mass spectrometry
WO2008007069A2 (en) * 2006-07-10 2008-01-17 Micromass Uk Limited Mass spectrometer
GB0622780D0 (en) 2006-11-15 2006-12-27 Micromass Ltd Mass spectrometer
GB0718468D0 (en) 2007-09-21 2007-10-31 Micromass Ltd Mass spectrometer
GB0820308D0 (en) * 2008-11-06 2008-12-17 Micromass Ltd Mass spectrometer
GB201000852D0 (en) * 2010-01-19 2010-03-03 Micromass Ltd Mass spectrometer
KR20140020152A (en) * 2012-08-08 2014-02-18 (주)영린기기 Rf/dc ion guide for mass spectrometer
WO2015092399A1 (en) 2013-12-19 2015-06-25 Micromass Uk Limited High pressure mass resolving ion guide with axial field
DE112014005868T5 (en) 2013-12-24 2016-09-15 Micromass Uk Limited Travel wave IMS with countercurrent of gas
GB201323004D0 (en) * 2013-12-24 2014-02-12 Micromass Ltd Travelling wave IMS with counterflow of gas
WO2015198721A1 (en) * 2014-06-25 2015-12-30 株式会社 日立ハイテクノロジーズ Mass spectrometer
CN107665806B (en) 2016-07-28 2019-11-26 株式会社岛津制作所 Mass spectrograph, ion optics and the method to the operation of mass spectrograph intermediate ion
CN113066713A (en) 2020-01-02 2021-07-02 株式会社岛津制作所 Ion optical device, mass spectrometer, and ion manipulation method
US11600480B2 (en) * 2020-09-22 2023-03-07 Thermo Finnigan Llc Methods and apparatus for ion transfer by ion bunching

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206506A (en) * 1991-02-12 1993-04-27 Kirchner Nicholas J Ion processing: control and analysis
US6111250A (en) * 1995-08-11 2000-08-29 Mds Health Group Limited Quadrupole with axial DC field
US6483109B1 (en) * 1999-08-26 2002-11-19 University Of New Hampshire Multiple stage mass spectrometer
US20040124354A1 (en) * 2002-11-08 2004-07-01 Bateman Robert Harold Mass spectrometer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002184347A (en) * 2000-12-12 2002-06-28 Shimadzu Corp Mass spectroscope device
JP3791479B2 (en) * 2002-09-17 2006-06-28 株式会社島津製作所 Ion guide
ATE507576T1 (en) * 2004-01-09 2011-05-15 Micromass Ltd ION EXTRACTION DEVICES AND METHOD FOR THE SELECTIVE EXTRACTION OF IONS
JP4193734B2 (en) * 2004-03-11 2008-12-10 株式会社島津製作所 Mass spectrometer
GB0522327D0 (en) * 2005-11-01 2005-12-07 Micromass Ltd Mass spectrometer
EP1956635B1 (en) * 2005-11-28 2013-05-15 Hitachi, Ltd. Ion guide device, ion reactor, and mass analyzer

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206506A (en) * 1991-02-12 1993-04-27 Kirchner Nicholas J Ion processing: control and analysis
US6111250A (en) * 1995-08-11 2000-08-29 Mds Health Group Limited Quadrupole with axial DC field
US6483109B1 (en) * 1999-08-26 2002-11-19 University Of New Hampshire Multiple stage mass spectrometer
US20040124354A1 (en) * 2002-11-08 2004-07-01 Bateman Robert Harold Mass spectrometer

Also Published As

Publication number Publication date
EP2013895A2 (en) 2009-01-14
EP2013895B8 (en) 2019-07-17
JP5290960B2 (en) 2013-09-18
WO2007125354A2 (en) 2007-11-08
JP2009535761A (en) 2009-10-01
HK1132839A1 (en) 2010-03-05
EP2013895B1 (en) 2018-09-12
CA2650390C (en) 2017-05-16
CA2650390A1 (en) 2007-11-08

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