WO2007117964A3 - Apparatus and method for vaccine development using ultrasound technology - Google Patents

Apparatus and method for vaccine development using ultrasound technology Download PDF

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Publication number
WO2007117964A3
WO2007117964A3 PCT/US2007/064842 US2007064842W WO2007117964A3 WO 2007117964 A3 WO2007117964 A3 WO 2007117964A3 US 2007064842 W US2007064842 W US 2007064842W WO 2007117964 A3 WO2007117964 A3 WO 2007117964A3
Authority
WO
WIPO (PCT)
Prior art keywords
ultrasound
bacterium
solution
virus
infectious agent
Prior art date
Application number
PCT/US2007/064842
Other languages
French (fr)
Other versions
WO2007117964A2 (en
Inventor
Eilaz P Babaev
Original Assignee
Eilaz P Babaev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eilaz P Babaev filed Critical Eilaz P Babaev
Priority to EP07759299A priority Critical patent/EP1998803A4/en
Priority to JP2009503185A priority patent/JP2009531454A/en
Publication of WO2007117964A2 publication Critical patent/WO2007117964A2/en
Publication of WO2007117964A3 publication Critical patent/WO2007117964A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/06—Hydrolysis; Cell lysis; Extraction of intracellular or cell wall material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • C12N1/066—Lysis of microorganisms by physical methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)

Abstract

Method and device for the creation of vaccines using ultrasonic waves, comprised of an ultrasound generator and a transducer to produce ultrasonic waves, is disclosed. The transducer has a specific ultrasound tip depending upon the type of delivery method utilized and depending on the shape of the vial containing the solution of the virus, bacterium, or other infectious agent. The apparatus delivers ultrasonic waves to solution either directly through the insertion of the ultrasound tip into the solution through a coupling medium adjacent to the vial or near the vial, or through an air or gas medium. The ultrasound waves have the effect of destroying the viable virus, bacterium, or other infectious agent and of releasing the appropriate antigens, thus resulting in a vaccine for that virus, bacterium, or other infectious agent.
PCT/US2007/064842 2006-03-29 2007-03-23 Apparatus and method for vaccine development using ultrasound technology WO2007117964A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP07759299A EP1998803A4 (en) 2006-03-29 2007-03-23 Apparatus and method for vaccine development using ultrasound technology
JP2009503185A JP2009531454A (en) 2006-03-29 2007-03-23 Apparatus and method for vaccine development using ultrasonic technology

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/393,180 US7943352B2 (en) 2006-03-29 2006-03-29 Apparatus and methods for vaccine development using ultrasound technology
US11/393,180 2006-03-29

Publications (2)

Publication Number Publication Date
WO2007117964A2 WO2007117964A2 (en) 2007-10-18
WO2007117964A3 true WO2007117964A3 (en) 2009-01-29

Family

ID=38559305

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/064842 WO2007117964A2 (en) 2006-03-29 2007-03-23 Apparatus and method for vaccine development using ultrasound technology

Country Status (5)

Country Link
US (2) US7943352B2 (en)
EP (1) EP1998803A4 (en)
JP (1) JP2009531454A (en)
CN (1) CN101553250A (en)
WO (1) WO2007117964A2 (en)

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WO2012125708A2 (en) * 2011-03-15 2012-09-20 E. I. Du Pont De Nemours And Company Device for shearing nucleic acids and particulates
DE102012219575A1 (en) * 2012-10-25 2014-04-30 Robert Bosch Gmbh Lysing devices, methods and system

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Also Published As

Publication number Publication date
US20080095799A1 (en) 2008-04-24
CN101553250A (en) 2009-10-07
EP1998803A2 (en) 2008-12-10
WO2007117964A2 (en) 2007-10-18
US20070231346A1 (en) 2007-10-04
US7842249B2 (en) 2010-11-30
EP1998803A4 (en) 2009-12-23
US7943352B2 (en) 2011-05-17
JP2009531454A (en) 2009-09-03

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