WO2007110052A3 - Method for inactivating unwanted organisms in blood plasma, especially viruses - Google Patents

Method for inactivating unwanted organisms in blood plasma, especially viruses Download PDF

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Publication number
WO2007110052A3
WO2007110052A3 PCT/DE2007/000525 DE2007000525W WO2007110052A3 WO 2007110052 A3 WO2007110052 A3 WO 2007110052A3 DE 2007000525 W DE2007000525 W DE 2007000525W WO 2007110052 A3 WO2007110052 A3 WO 2007110052A3
Authority
WO
WIPO (PCT)
Prior art keywords
blood plasma
unwanted organisms
especially viruses
inactivating
viruses
Prior art date
Application number
PCT/DE2007/000525
Other languages
German (de)
French (fr)
Other versions
WO2007110052A2 (en
Inventor
Gerd Heim
Original Assignee
Heim Heidrun
Gerd Heim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heim Heidrun, Gerd Heim filed Critical Heim Heidrun
Publication of WO2007110052A2 publication Critical patent/WO2007110052A2/en
Publication of WO2007110052A3 publication Critical patent/WO2007110052A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029—Radiation
    • A61L2/0052—Visible light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/10—Apparatus features
    • A61L2202/12—Apparatus for isolating biocidal substances from the environment
    • A61L2202/122—Chambers for sterilisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20—Targets to be treated
    • A61L2202/22—Blood or products thereof

Abstract

In order to inactivate with complete reliability the viruses and the like present in blood plasma immediately when it is obtained, it is proposed to add a porphyrin, in particular a chlorin e6, to the blood plasma immediately when it is obtained from blood (B), and to irradiate the mixture (10, 10a) with xenon rays. An apparatus with a special irradiation apparatus is likewise proposed for this purpose.
PCT/DE2007/000525 2006-03-24 2007-03-21 Method for inactivating unwanted organisms in blood plasma, especially viruses WO2007110052A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE200610014184 DE102006014184A1 (en) 2006-03-24 2006-03-24 Deactivating unwanted organisms in blood plasma, especially viruses, involves adding porphyrin to blood plasma immediately after extracting it from blood and irradiating mixture with xenon radiation
DE102006014184.9 2006-03-24

Publications (2)

Publication Number Publication Date
WO2007110052A2 WO2007110052A2 (en) 2007-10-04
WO2007110052A3 true WO2007110052A3 (en) 2008-03-20

Family

ID=38256975

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2007/000525 WO2007110052A2 (en) 2006-03-24 2007-03-21 Method for inactivating unwanted organisms in blood plasma, especially viruses

Country Status (2)

Country Link
DE (1) DE102006014184A1 (en)
WO (1) WO2007110052A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112386717B (en) * 2020-12-11 2022-05-24 西安市中心医院 Disposable blood virus inactivation device

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995000631A1 (en) * 1993-06-23 1995-01-05 New York Blood Center, Inc. System for viral inactivation of blood
US5660731A (en) * 1994-11-08 1997-08-26 Pall Corporation Filter for separating photoactive agent
US5935092A (en) * 1990-12-20 1999-08-10 Baxter International Inc. Systems and methods for removing free and entrained contaminants in plasma
DE20014311U1 (en) * 2000-08-15 2001-02-15 Heim Medizintechnik Gmbh Filter arrangement for separating blood into plasma and cellular components
US20020015662A1 (en) * 2000-06-15 2002-02-07 Hlavinka Dennis J. Inactivation of contaminants using photosensitizers and pulsed light

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4878891A (en) * 1987-06-25 1989-11-07 Baylor Research Foundation Method for eradicating infectious biological contaminants in body tissues
RU2118177C1 (en) * 1993-08-02 1998-08-27 Алексей Борисович Башкиров Method of inducing immune response of body
DE10162712A1 (en) * 2001-12-19 2003-07-17 Blutspendienst Der Landesverba Process for inactivating bacteria and leukocytes in blood or blood products

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5935092A (en) * 1990-12-20 1999-08-10 Baxter International Inc. Systems and methods for removing free and entrained contaminants in plasma
US6695805B1 (en) * 1990-12-20 2004-02-24 Baxter International Inc. Systems and methods for removing free and entrained contaminants in plasma
WO1995000631A1 (en) * 1993-06-23 1995-01-05 New York Blood Center, Inc. System for viral inactivation of blood
US5660731A (en) * 1994-11-08 1997-08-26 Pall Corporation Filter for separating photoactive agent
US20020015662A1 (en) * 2000-06-15 2002-02-07 Hlavinka Dennis J. Inactivation of contaminants using photosensitizers and pulsed light
DE20014311U1 (en) * 2000-08-15 2001-02-15 Heim Medizintechnik Gmbh Filter arrangement for separating blood into plasma and cellular components

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
"Römpp Online", 24 July 2007, GEORG THIEME VERLAG, STUTTGART, XP002443782 *
SUOMELA H: "INACTIVATION OF VIRUSES IN BLOOD AND PLASMA PRODUCTS", TRANSFUSION MEDICINE, OXFORD, GB, vol. 7, no. 1, 1993, pages 42 - 57, XP000573510 *

Also Published As

Publication number Publication date
DE102006014184A1 (en) 2007-09-27
WO2007110052A2 (en) 2007-10-04

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