WO2007106158A3 - Biodegradable implants having accelerated biodegradation properties in vivo - Google Patents

Biodegradable implants having accelerated biodegradation properties in vivo Download PDF

Info

Publication number
WO2007106158A3
WO2007106158A3 PCT/US2006/046283 US2006046283W WO2007106158A3 WO 2007106158 A3 WO2007106158 A3 WO 2007106158A3 US 2006046283 W US2006046283 W US 2006046283W WO 2007106158 A3 WO2007106158 A3 WO 2007106158A3
Authority
WO
WIPO (PCT)
Prior art keywords
vivo
implant
biodegradable implants
present
biodegradable
Prior art date
Application number
PCT/US2006/046283
Other languages
French (fr)
Other versions
WO2007106158A2 (en
Inventor
Emily E Rusk
F Anthony Headley Jr
Claude Clerc
Original Assignee
Boston Scient Scimed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Scient Scimed Inc filed Critical Boston Scient Scimed Inc
Priority to EP06838950A priority Critical patent/EP1993628A2/en
Publication of WO2007106158A2 publication Critical patent/WO2007106158A2/en
Publication of WO2007106158A3 publication Critical patent/WO2007106158A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58Materials at least partially resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148Materials at least partially resorbable by the body

Abstract

The present invention is directed to a biodegradable implant including a biodegradable polymer previously exposed to conditions of biodegradation such as chemical, thermal or radiation degradation. The present invention further includes the possibility of attaching axial runners to the implant. The present invention is further directed to a method of forming a biodegradable implant, such as a stent, by irradiation of the individual filaments or fibers, or irradiation of the formed implant.
PCT/US2006/046283 2006-02-28 2006-12-05 Biodegradable implants having accelerated biodegradation properties in vivo WO2007106158A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP06838950A EP1993628A2 (en) 2006-02-28 2006-12-05 Biodegradable implants having accelerated biodegradation properties in vivo

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/363,836 US20070203564A1 (en) 2006-02-28 2006-02-28 Biodegradable implants having accelerated biodegradation properties in vivo
US11/363,836 2006-02-28

Publications (2)

Publication Number Publication Date
WO2007106158A2 WO2007106158A2 (en) 2007-09-20
WO2007106158A3 true WO2007106158A3 (en) 2008-04-17

Family

ID=38328587

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/046283 WO2007106158A2 (en) 2006-02-28 2006-12-05 Biodegradable implants having accelerated biodegradation properties in vivo

Country Status (3)

Country Link
US (1) US20070203564A1 (en)
EP (1) EP1993628A2 (en)
WO (1) WO2007106158A2 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5961545A (en) * 1997-01-17 1999-10-05 Meadox Medicals, Inc. EPTFE graft-stent composite device
US8083806B2 (en) * 2005-02-04 2011-12-27 Poly-Med, Inc. Radiation and radiochemically sterilized fiber-reinforced, composite urinogenital stents
WO2008112596A2 (en) * 2007-03-09 2008-09-18 Anthem Orthopaedics Llc Implantable device with bioabsorbable layer, kit and method for use therewith, and apparatus for preparing same
DE102007031945A1 (en) * 2007-07-06 2009-01-08 Resoimplant Gmbh Bioresorbable implant
US8017396B2 (en) * 2008-02-22 2011-09-13 Vijay Kumar Cellulose based heart valve prosthesis
US20100125326A1 (en) * 2008-11-20 2010-05-20 Medtronic Vascular, Inc. Braided Stent With a Shortenable Tether
JP5487122B2 (en) * 2009-02-06 2014-05-07 学校法人慶應義塾 Stent for use in biological tubular organs
US9216198B2 (en) * 2009-03-30 2015-12-22 The Board Of Regents, The University Of Texas System Compositions and medical devices for controlled release of nitric oxide and methods of production thereof
US9050264B2 (en) 2009-11-07 2015-06-09 University Of Iowa Research Foundation Cellulose capsules and methods for making them
US8834776B2 (en) * 2011-05-10 2014-09-16 Abbott Cardiovascular Systems Inc. Control of degradation profile of bioabsorbable poly(l-lactide) scaffold
GB2499211B (en) 2012-02-08 2016-03-02 Cook Medical Technologies Llc Bioabsorbable stent and implantable medical device
US20140065090A1 (en) * 2012-08-31 2014-03-06 W. L. Gore & Associates, Inc. Reactive Oxidative Species Generating Materials and Methods of Use
US9259435B2 (en) * 2012-08-31 2016-02-16 W. L. Gore & Associates, Inc. Reactive oxidative species generating materials and methods of use
US20140142683A1 (en) * 2012-11-21 2014-05-22 Lee Core Stent with elastomeric elements
US10293044B2 (en) 2014-04-18 2019-05-21 Auburn University Particulate formulations for improving feed conversion rate in a subject
CN106232106B (en) 2014-04-18 2020-08-11 奥本大学 Particulate vaccine formulations for inducing innate and adaptive immunity
US20160374838A1 (en) * 2015-06-29 2016-12-29 Abbott Cardiovascular Systems Inc. Drug-eluting coatings on poly(dl-lactide)-based scaffolds
CA3017310C (en) 2016-03-14 2023-09-26 Tazuke Kofukai Nerve regeneration-inducing material
US10583199B2 (en) 2016-04-26 2020-03-10 Northwestern University Nanocarriers having surface conjugated peptides and uses thereof for sustained local release of drugs
CN106308265B (en) * 2016-09-14 2018-03-20 嘉兴美东生物科技有限公司 A kind of washable acid fiber by polylactic material quilt and its manufacture craft

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991017789A1 (en) * 1990-05-18 1991-11-28 Stack Richard S Bioabsorbable stent
EP0493788A1 (en) * 1990-12-29 1992-07-08 MUDR. MILAN KRAJICEK CSc. Three-layer vascular prosthesis
WO1997046267A1 (en) * 1996-06-03 1997-12-11 Gore Enterprise Holdings, Inc. Materials and methods for the immobilization of bioactive species onto biodegradable polymers
WO1999033410A2 (en) * 1997-12-15 1999-07-08 The Cleveland Clinic Foundation Stent having a programmed pattern of in vivo degradation
WO2001015751A1 (en) * 1999-09-01 2001-03-08 Bioxid Oy Novel multilayered material bearing a biologically active agent and the preparation thereof
WO2004091714A2 (en) * 2003-04-08 2004-10-28 Scimed Life Systems, Inc. Implantable or insertable medical devices containing radiation-crosslinked polymer for controlled delivery of a therapeutic agent
US20050025801A1 (en) * 2003-07-31 2005-02-03 Richard Robert E. Implantable or insertable medical devices containing radiation-treated polymer for improved delivery of therapeutic agent
EP1698358A1 (en) * 2003-12-26 2006-09-06 Cardio Incorporated Transplantable biomaterial and method of preparing the same

Family Cites Families (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4435590A (en) * 1981-08-06 1984-03-06 Ethicon, Inc. Radiation sterilizable absorbable polymeric materials and methods for manufacturing the same
US6004346A (en) * 1990-02-28 1999-12-21 Medtronic, Inc. Intralumenal drug eluting prosthesis
US5545208A (en) * 1990-02-28 1996-08-13 Medtronic, Inc. Intralumenal drug eluting prosthesis
US5571166A (en) * 1992-03-19 1996-11-05 Medtronic, Inc. Method of making an intraluminal stent
US5735892A (en) * 1993-08-18 1998-04-07 W. L. Gore & Associates, Inc. Intraluminal stent graft
WO1995010989A1 (en) * 1993-10-19 1995-04-27 Scimed Life Systems, Inc. Intravascular stent pump
US6334872B1 (en) * 1994-02-18 2002-01-01 Organogenesis Inc. Method for treating diseased or damaged organs
EP0754017B1 (en) * 1994-04-29 2002-06-19 SciMed Life Systems, Inc. Stent with collagen
US6451047B2 (en) * 1995-03-10 2002-09-17 Impra, Inc. Encapsulated intraluminal stent-graft and methods of making same
WO1997009006A1 (en) * 1995-09-01 1997-03-13 Emory University Endovascular support device and method of use
FI954565A0 (en) * 1995-09-27 1995-09-27 Biocon Oy Biologically applied polymeric material to the implant and foil preparation
US6689162B1 (en) * 1995-10-11 2004-02-10 Boston Scientific Scimed, Inc. Braided composite prosthesis
US5843158A (en) * 1996-01-05 1998-12-01 Medtronic, Inc. Limited expansion endoluminal prostheses and methods for their use
US6428571B1 (en) * 1996-01-22 2002-08-06 Scimed Life Systems, Inc. Self-sealing PTFE vascular graft and manufacturing methods
US5718159A (en) * 1996-04-30 1998-02-17 Schneider (Usa) Inc. Process for manufacturing three-dimensional braided covered stent
US6592617B2 (en) * 1996-04-30 2003-07-15 Boston Scientific Scimed, Inc. Three-dimensional braided covered stent
US6228900B1 (en) * 1996-07-09 2001-05-08 The Orthopaedic Hospital And University Of Southern California Crosslinking of polyethylene for low wear using radiation and thermal treatments
US5833651A (en) * 1996-11-08 1998-11-10 Medtronic, Inc. Therapeutic intraluminal stents
US5957974A (en) * 1997-01-23 1999-09-28 Schneider (Usa) Inc Stent graft with braided polymeric sleeve
US5980551A (en) * 1997-02-07 1999-11-09 Endovasc Ltd., Inc. Composition and method for making a biodegradable drug delivery stent
US6174330B1 (en) * 1997-08-01 2001-01-16 Schneider (Usa) Inc Bioabsorbable marker having radiopaque constituents
US5980564A (en) * 1997-08-01 1999-11-09 Schneider (Usa) Inc. Bioabsorbable implantable endoprosthesis with reservoir
US6245103B1 (en) * 1997-08-01 2001-06-12 Schneider (Usa) Inc Bioabsorbable self-expanding stent
US6626939B1 (en) * 1997-12-18 2003-09-30 Boston Scientific Scimed, Inc. Stent-graft with bioabsorbable structural support
US7713297B2 (en) * 1998-04-11 2010-05-11 Boston Scientific Scimed, Inc. Drug-releasing stent with ceramic-containing layer
US6156064A (en) * 1998-08-14 2000-12-05 Schneider (Usa) Inc Stent-graft-membrane and method of making the same
ATE407641T1 (en) * 1999-02-01 2008-09-15 Univ Texas WOVEN, TWO-WAY AND THREE-WAY STENTS AND METHODS OF PRODUCTION THEREOF
US6364903B2 (en) * 1999-03-19 2002-04-02 Meadox Medicals, Inc. Polymer coated stent
JP2002541916A (en) * 1999-04-21 2002-12-10 ハウメディカ・アスティオニクス・コーポレイション Selective cross-linked polyethylene shaping device
US7682647B2 (en) * 1999-09-03 2010-03-23 Advanced Cardiovascular Systems, Inc. Thermal treatment of a drug eluting implantable medical device
US6475235B1 (en) * 1999-11-16 2002-11-05 Iowa-India Investments Company, Limited Encapsulated stent preform
US7736687B2 (en) * 2006-01-31 2010-06-15 Advance Bio Prosthetic Surfaces, Ltd. Methods of making medical devices
US6251136B1 (en) * 1999-12-08 2001-06-26 Advanced Cardiovascular Systems, Inc. Method of layering a three-coated stent using pharmacological and polymeric agents
WO2001068158A1 (en) * 2000-03-15 2001-09-20 Orbus Medical Technologies Inc. Coating that promotes endothelial cell adherence
US6770086B1 (en) * 2000-11-02 2004-08-03 Scimed Life Systems, Inc. Stent covering formed of porous polytetraflouroethylene
US20040030377A1 (en) * 2001-10-19 2004-02-12 Alexander Dubson Medicated polymer-coated stent assembly
US7244272B2 (en) * 2000-12-19 2007-07-17 Nicast Ltd. Vascular prosthesis and method for production thereof
US20020084178A1 (en) * 2000-12-19 2002-07-04 Nicast Corporation Ltd. Method and apparatus for manufacturing polymer fiber shells via electrospinning
US6471980B2 (en) * 2000-12-22 2002-10-29 Avantec Vascular Corporation Intravascular delivery of mycophenolic acid
US6752829B2 (en) * 2001-01-30 2004-06-22 Scimed Life Systems, Inc. Stent with channel(s) for containing and delivering a biologically active material and method for manufacturing the same
US6871279B2 (en) * 2001-03-20 2005-03-22 Networks Associates Technology, Inc. Method and apparatus for securely and dynamically managing user roles in a distributed system
US6551352B2 (en) * 2001-05-03 2003-04-22 Bionx Implants, Inc. Method for attaching axial filaments to a self expanding stent
US20020165601A1 (en) * 2001-05-04 2002-11-07 Clerc Claude O. Bioabsorbable stent-graft and covered stent
US8182527B2 (en) * 2001-05-07 2012-05-22 Cordis Corporation Heparin barrier coating for controlled drug release
US7828833B2 (en) * 2001-06-11 2010-11-09 Boston Scientific Scimed, Inc. Composite ePTFE/textile prosthesis
US6656216B1 (en) * 2001-06-29 2003-12-02 Advanced Cardiovascular Systems, Inc. Composite stent with regioselective material
EP1273314A1 (en) * 2001-07-06 2003-01-08 Terumo Kabushiki Kaisha Stent
US7022135B2 (en) * 2001-08-17 2006-04-04 Medtronic, Inc. Film with highly porous vascular graft prostheses
US7989018B2 (en) * 2001-09-17 2011-08-02 Advanced Cardiovascular Systems, Inc. Fluid treatment of a polymeric coating on an implantable medical device
US6827737B2 (en) * 2001-09-25 2004-12-07 Scimed Life Systems, Inc. EPTFE covering for endovascular prostheses and method of manufacture
US6752826B2 (en) * 2001-12-14 2004-06-22 Thoratec Corporation Layered stent-graft and methods of making the same
US7473273B2 (en) * 2002-01-22 2009-01-06 Medtronic Vascular, Inc. Stent assembly with therapeutic agent exterior banding
US20030153901A1 (en) * 2002-02-08 2003-08-14 Atrium Medical Corporation Drug delivery panel
US7993390B2 (en) * 2002-02-08 2011-08-09 Boston Scientific Scimed, Inc. Implantable or insertable medical device resistant to microbial growth and biofilm formation
US7288111B1 (en) * 2002-03-26 2007-10-30 Thoratec Corporation Flexible stent and method of making the same
US7261734B2 (en) * 2002-04-23 2007-08-28 Boston Scientific Scimed, Inc. Resorption-controllable medical implants
US7105021B2 (en) * 2002-04-25 2006-09-12 Scimed Life Systems, Inc. Implantable textile prostheses having PTFE cold drawn yarns
EP2851097A3 (en) * 2002-07-12 2015-06-10 Cook Medical Technologies LLC Drug-coated angioplasty balloons
US7303575B2 (en) * 2002-08-01 2007-12-04 Lumen Biomedical, Inc. Embolism protection devices
EP1528901A1 (en) * 2002-08-15 2005-05-11 GMP Cardiac Care, Inc. Stent-graft with rails
US7029495B2 (en) * 2002-08-28 2006-04-18 Scimed Life Systems, Inc. Medical devices and methods of making the same
US7326238B1 (en) * 2002-09-30 2008-02-05 Abbott Cardiovascular Systems Inc. Method and apparatus for treating vulnerable plaque
US20060121080A1 (en) * 2002-11-13 2006-06-08 Lye Whye K Medical devices having nanoporous layers and methods for making the same
US7094256B1 (en) * 2002-12-16 2006-08-22 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical device containing polycationic peptides
US7718556B2 (en) * 2002-12-16 2010-05-18 Gunze Limited Medical film
US7135040B2 (en) * 2002-12-23 2006-11-14 Agency For Science, Technology And Research Medical guide tubes
US7105018B1 (en) * 2002-12-30 2006-09-12 Advanced Cardiovascular Systems, Inc. Drug-eluting stent cover and method of use
US7311727B2 (en) * 2003-02-05 2007-12-25 Board Of Trustees Of The University Of Arkansas Encased stent
US6932930B2 (en) * 2003-03-10 2005-08-23 Synecor, Llc Intraluminal prostheses having polymeric material with selectively modified crystallinity and methods of making same
US7452374B2 (en) * 2003-04-24 2008-11-18 Maquet Cardiovascular, Llc AV grafts with rapid post-operative self-sealing capabilities
US7214383B2 (en) * 2003-06-16 2007-05-08 Bruce Alan Daniels Stent for delivery of drugs to the endothelium
US20050038501A1 (en) * 2003-08-12 2005-02-17 Moore James E. Dynamic stent
US7806924B2 (en) * 2004-02-18 2010-10-05 Cordis Corporation Implantable structures for local vascular delivery of cladribine in combination with rapamycin for restenosis
US7761138B2 (en) * 2004-03-12 2010-07-20 Boston Scientific Scimed, Inc. MRI and X-ray visualization
US7794490B2 (en) * 2004-06-22 2010-09-14 Boston Scientific Scimed, Inc. Implantable medical devices with antimicrobial and biodegradable matrices
US20060058867A1 (en) * 2004-09-15 2006-03-16 Thistle Robert C Elastomeric radiopaque adhesive composite and prosthesis
WO2006053270A2 (en) * 2004-11-10 2006-05-18 Boston Scientific Limited Atraumatic stent with reduced deployment force, method for making the same and method and apparatus for deploying and positioning the stent
US7455688B2 (en) * 2004-11-12 2008-11-25 Con Interventional Systems, Inc. Ostial stent
US8043361B2 (en) * 2004-12-10 2011-10-25 Boston Scientific Scimed, Inc. Implantable medical devices, and methods of delivering the same
US7922761B2 (en) * 2005-01-25 2011-04-12 Nicast Ltd. Artificial vascular prosthesis
US7655584B2 (en) * 2005-07-29 2010-02-02 Gore Enterprise Holdings, Inc. Highly porous self-cohered web materials
US8048150B2 (en) * 2006-04-12 2011-11-01 Boston Scientific Scimed, Inc. Endoprosthesis having a fiber meshwork disposed thereon
US7951194B2 (en) * 2006-05-26 2011-05-31 Abbott Cardiovascular Sysetms Inc. Bioabsorbable stent with radiopaque coating
JP2010503491A (en) * 2006-09-15 2010-02-04 ボストン サイエンティフィック リミテッド Bioerodible endoprosthesis with biologically stable inorganic layers
CA2663220A1 (en) * 2006-09-15 2008-03-20 Boston Scientific Limited Medical devices and methods of making the same
US8002821B2 (en) * 2006-09-18 2011-08-23 Boston Scientific Scimed, Inc. Bioerodible metallic ENDOPROSTHESES
US8071156B2 (en) * 2009-03-04 2011-12-06 Boston Scientific Scimed, Inc. Endoprostheses

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991017789A1 (en) * 1990-05-18 1991-11-28 Stack Richard S Bioabsorbable stent
EP0493788A1 (en) * 1990-12-29 1992-07-08 MUDR. MILAN KRAJICEK CSc. Three-layer vascular prosthesis
WO1997046267A1 (en) * 1996-06-03 1997-12-11 Gore Enterprise Holdings, Inc. Materials and methods for the immobilization of bioactive species onto biodegradable polymers
WO1999033410A2 (en) * 1997-12-15 1999-07-08 The Cleveland Clinic Foundation Stent having a programmed pattern of in vivo degradation
WO2001015751A1 (en) * 1999-09-01 2001-03-08 Bioxid Oy Novel multilayered material bearing a biologically active agent and the preparation thereof
WO2004091714A2 (en) * 2003-04-08 2004-10-28 Scimed Life Systems, Inc. Implantable or insertable medical devices containing radiation-crosslinked polymer for controlled delivery of a therapeutic agent
US20050025801A1 (en) * 2003-07-31 2005-02-03 Richard Robert E. Implantable or insertable medical devices containing radiation-treated polymer for improved delivery of therapeutic agent
EP1698358A1 (en) * 2003-12-26 2006-09-06 Cardio Incorporated Transplantable biomaterial and method of preparing the same

Also Published As

Publication number Publication date
EP1993628A2 (en) 2008-11-26
WO2007106158A2 (en) 2007-09-20
US20070203564A1 (en) 2007-08-30

Similar Documents

Publication Publication Date Title
WO2007106158A3 (en) Biodegradable implants having accelerated biodegradation properties in vivo
WO2009005909A3 (en) Biodegradable triblock copolymers for implantable devices
WO2009117241A3 (en) Controlled degradation of magnesium stents
WO2008098927A3 (en) Degradable reservoir implants
WO2011084521A3 (en) Therapeutic polymeric nanoparticles comprising epothilone and methods of making and using same
WO2006110197A3 (en) Polymer biodegradable medical device
WO2007092559A3 (en) A poly (diol-co-citrate) hydroxyapatite composite for tissue engineering and orthopaedic fixation devices
WO2007125391A3 (en) Stent manufacturing methods
WO2009155206A3 (en) Bioabsorbable polymeric stent with improved structural and molecular weight integrity
WO2006099315A3 (en) Electrospun cell matrices
TW200801113A (en) The polylactic acid composition and the deep dyeing fiber manufactured from the same
WO2008089434A3 (en) Biodegradable endoprostheses and methods for their fabrication
ATE526048T1 (en) COATED BIODEGRADABLE METALLIC IMPLANT
CA2527975A1 (en) Biodegradable stents comprising a shape memory polymeric material
WO2009024778A3 (en) Bioactive material
WO2010017090A3 (en) Tube expansion process for semicrystalline polymers to maximize fracture toughness
IN2012DN00920A (en)
WO2007111811A3 (en) Corrosion resistant coatings for biodegradable metallic implants
WO2007050415A3 (en) Poly(ester urea) polymers and methods of use
WO2008077172A3 (en) Use of polymers
DK2712610T3 (en) Methods for the preparation of cyclic lipid implants for intraocular use
WO2008122594A3 (en) Partially biodegradable therapeutic implant for bone and cartilage repair
WO2009064767A3 (en) Bactericidal nanofibers, and methods of use thereof
WO2006076416A3 (en) Three dimensional cell protector/pore architecture formation for bone and tissue constructs
EP1967219A3 (en) Tissue growth devices

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 06838950

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2006838950

Country of ref document: EP