WO2007095185A3 - Variants in complement regulatory genes predict age-related macular degeneration - Google Patents
Variants in complement regulatory genes predict age-related macular degeneration Download PDFInfo
- Publication number
- WO2007095185A3 WO2007095185A3 PCT/US2007/003696 US2007003696W WO2007095185A3 WO 2007095185 A3 WO2007095185 A3 WO 2007095185A3 US 2007003696 W US2007003696 W US 2007003696W WO 2007095185 A3 WO2007095185 A3 WO 2007095185A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- variants
- macular degeneration
- related macular
- regulatory genes
- complement regulatory
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
Abstract
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2008554415A JP5290772B2 (en) | 2006-02-13 | 2007-02-13 | Mutants in complement regulatory genes predict age-related macular degeneration |
AU2007215218A AU2007215218B2 (en) | 2006-02-13 | 2007-02-13 | Variants in complement regulatory genes predict age-related macular degeneration |
CA002638916A CA2638916A1 (en) | 2006-02-13 | 2007-02-13 | Variants in complement regulatory genes predict age-related macular degeneration |
NZ570431A NZ570431A (en) | 2006-02-13 | 2007-02-13 | Variants in complement regulatory genes predict age-related macular degeneration |
EP07750527A EP1989319A4 (en) | 2006-02-13 | 2007-02-13 | Variants in complement regulatory genes predict age-related macular degeneration |
IL193396A IL193396A (en) | 2006-02-13 | 2008-08-12 | Variants in complement regulatory genes to predict age-related macular degeneration |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US77298906P | 2006-02-13 | 2006-02-13 | |
US60/772,989 | 2006-02-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007095185A2 WO2007095185A2 (en) | 2007-08-23 |
WO2007095185A3 true WO2007095185A3 (en) | 2008-09-25 |
Family
ID=38372062
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2007/003696 WO2007095185A2 (en) | 2006-02-13 | 2007-02-13 | Variants in complement regulatory genes predict age-related macular degeneration |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1989319A4 (en) |
JP (1) | JP5290772B2 (en) |
CN (1) | CN101421409A (en) |
AU (1) | AU2007215218B2 (en) |
CA (1) | CA2638916A1 (en) |
IL (1) | IL193396A (en) |
NZ (1) | NZ570431A (en) |
WO (1) | WO2007095185A2 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8012683B2 (en) | 2006-02-13 | 2011-09-06 | University Of Iowa Research Foundation | Variants in complement regulatory genes predict age-related macular degeneration |
US20120141994A1 (en) * | 2009-04-29 | 2012-06-07 | Deangelis Margaret M | Methods and compositions for prognosing and detecting age-related macular degeneration |
WO2011006161A2 (en) | 2009-07-10 | 2011-01-13 | The Regents Of The University Of Michigan | Compositions and methods for diagnosing and treating macular degeneration |
US20110104154A1 (en) * | 2009-10-30 | 2011-05-05 | Alcon Research, Ltd. | Single nucleotide polymorphisms and genes associated with age-related macular degeneration |
US9056874B2 (en) | 2012-05-04 | 2015-06-16 | Novartis Ag | Complement pathway modulators and uses thereof |
CN102707068B (en) * | 2012-05-31 | 2015-03-18 | 北京大学 | Application of complement factor H (CFH) to genetic expression products of methamphetamine (METH) addiction patient |
WO2014143638A1 (en) | 2013-03-14 | 2014-09-18 | Novartis Ag | 2-(1h-indol-4-ylmethyl)-3h-imidazo[4,5-b]pyridine-6-carbonitrile derivatives as complement factor b inhibitors useful for the treatment of ophthalmic diseases |
US9676728B2 (en) | 2013-10-30 | 2017-06-13 | Novartis Ag | 2-benzyl-benzimidazole complement factor B inhibitors and uses thereof |
EP3102701A1 (en) * | 2014-02-07 | 2016-12-14 | Novartis AG | Impact of genetic factors on disease progression and response to anti-c5 antibody in geographic atrophy |
EP3233115B1 (en) * | 2014-12-19 | 2021-02-17 | Children's Hospital Medical Center | Methods and compositions related to transplant-associated thrombotic microangiopathy |
CN109082460B (en) * | 2018-09-27 | 2021-07-13 | 领航基因科技(杭州)有限公司 | Non-competitive probe design method, detection method and application applied to SNP typing |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5474796A (en) * | 1991-09-04 | 1995-12-12 | Protogene Laboratories, Inc. | Method and apparatus for conducting an array of chemical reactions on a support surface |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1985001051A1 (en) | 1983-09-02 | 1985-03-14 | Molecular Biosystems, Inc. | Oligonucleotide polymeric support system |
GB8810400D0 (en) | 1988-05-03 | 1988-06-08 | Southern E | Analysing polynucleotide sequences |
US5554501A (en) | 1992-10-29 | 1996-09-10 | Beckman Instruments, Inc. | Biopolymer synthesis using surface activated biaxially oriented polypropylene |
DE69503126T2 (en) | 1994-05-05 | 1998-11-12 | Beckman Instruments Inc | REPETITIVE OLIGONUCLEOTIDE MATRIX |
US5985567A (en) | 1997-08-15 | 1999-11-16 | Beckman Coulter, Inc. | Hybridization detection by pretreating bound single-stranded probes |
US6013789A (en) | 1998-02-20 | 2000-01-11 | Beckman Coulter, Inc. | Covalent attachment of biomolecules to derivatized polypropylene supports |
US20090017029A1 (en) * | 2004-11-18 | 2009-01-15 | Yale University | Methods and Compositions for Treating Ocular Disorders |
-
2007
- 2007-02-13 NZ NZ570431A patent/NZ570431A/en not_active IP Right Cessation
- 2007-02-13 EP EP07750527A patent/EP1989319A4/en not_active Withdrawn
- 2007-02-13 CA CA002638916A patent/CA2638916A1/en not_active Abandoned
- 2007-02-13 JP JP2008554415A patent/JP5290772B2/en not_active Expired - Fee Related
- 2007-02-13 CN CN200780012906.3A patent/CN101421409A/en active Pending
- 2007-02-13 AU AU2007215218A patent/AU2007215218B2/en not_active Ceased
- 2007-02-13 WO PCT/US2007/003696 patent/WO2007095185A2/en active Application Filing
-
2008
- 2008-08-12 IL IL193396A patent/IL193396A/en not_active IP Right Cessation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5474796A (en) * | 1991-09-04 | 1995-12-12 | Protogene Laboratories, Inc. | Method and apparatus for conducting an array of chemical reactions on a support surface |
Non-Patent Citations (3)
Title |
---|
ABRERA-ABELEDA M.A.: "Variations In The Complement Regulatory Genes Factor H and Factor H Related 5 Are Associated With Membranoproliferative Glomerulonephritis Type II", J. MED. GENET., vol. 43, 2006, pages 582 - 589, XP008102582 * |
BOERHINGER MANNHEIM: "Biochemical Catalog, Non-Radioactive Labeling and Detection of Nucleic Acids", 1997 * |
DATABASE SNP [online] "Cluster Report", XP008138645, Database accession no. (rs641153) * |
Also Published As
Publication number | Publication date |
---|---|
IL193396A (en) | 2013-03-24 |
AU2007215218A1 (en) | 2007-08-23 |
EP1989319A4 (en) | 2009-11-11 |
CN101421409A (en) | 2009-04-29 |
JP5290772B2 (en) | 2013-09-18 |
CA2638916A1 (en) | 2007-08-23 |
JP2009526524A (en) | 2009-07-23 |
EP1989319A2 (en) | 2008-11-12 |
AU2007215218B2 (en) | 2013-09-19 |
IL193396A0 (en) | 2009-05-04 |
WO2007095185A2 (en) | 2007-08-23 |
NZ570431A (en) | 2011-12-22 |
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