WO2007089948A3 - Improved apparatus and method for injection of fibrin sealant in spinal applications - Google Patents

Improved apparatus and method for injection of fibrin sealant in spinal applications Download PDF

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Publication number
WO2007089948A3
WO2007089948A3 PCT/US2007/003207 US2007003207W WO2007089948A3 WO 2007089948 A3 WO2007089948 A3 WO 2007089948A3 US 2007003207 W US2007003207 W US 2007003207W WO 2007089948 A3 WO2007089948 A3 WO 2007089948A3
Authority
WO
WIPO (PCT)
Prior art keywords
injection
improved apparatus
fibrin sealant
fluid
delivery tube
Prior art date
Application number
PCT/US2007/003207
Other languages
French (fr)
Other versions
WO2007089948A2 (en
Inventor
Mark Richards
Brian D Burkinshaw
Kevin Pauza
James B Rogan
John L Wheeler
Original Assignee
Spinal Restoration Inc
Mark Richards
Brian D Burkinshaw
Kevin Pauza
James B Rogan
John L Wheeler
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spinal Restoration Inc, Mark Richards, Brian D Burkinshaw, Kevin Pauza, James B Rogan, John L Wheeler filed Critical Spinal Restoration Inc
Publication of WO2007089948A2 publication Critical patent/WO2007089948A2/en
Publication of WO2007089948A3 publication Critical patent/WO2007089948A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/19Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00491Surgical glue applicators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00491Surgical glue applicators
    • A61B2017/00495Surgical glue applicators for two-component glue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M2005/3152Piston or piston-rod constructions, e.g. connection of piston with piston-rod including gearings to multiply or attenuate the piston displacing force
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M2005/3201Coaxially assembled needle cannulas placed on top of another, e.g. needles having different diameters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0021Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026Multi-lumen catheters with stationary elements
    • A61M25/0032Multi-lumen catheters with stationary elements characterized by at least one unconventionally shaped lumen, e.g. polygons, ellipsoids, wedges or shapes comprising concave and convex parts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2422Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
    • A61M5/2425Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by compression of deformable ampoule or carpule wall
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566Means improving security or handling thereof
    • A61M5/31573Accuracy improving means
    • A61M5/31575Accuracy improving means using scaling up or down transmissions, e.g. gearbox
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/31581Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by rotationally moving or pivoting actuator operated by user, e.g. an injection lever or handle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159Dose expelling manners
    • A61M5/31593Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/48Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for varying, regulating, indicating or limiting injection pressure
    • A61M5/486Indicating injection pressure

Abstract

An apparatus for percutaneous delivery of a sealant comprising: at least two fluid reservoirs, an introducer needle having a distal tip that is in fluid communication with at least one reservoir, a fluid delivery tube that is in fluid communication with a second reservoir, wherein the fluid delivery tube has a tip and wherein the fluid delivery tube is configured so that the tip of the fluid delivery tube does not extend past the distal tip of the introducer needle during use.
PCT/US2007/003207 2006-02-01 2007-02-01 Improved apparatus and method for injection of fibrin sealant in spinal applications WO2007089948A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US76402006P 2006-02-01 2006-02-01
US60/764,020 2006-02-01
US11/650,398 2007-01-05
US11/650,398 US8419722B2 (en) 2004-10-29 2007-01-05 Apparatus and method for injection of fibrin sealant in spinal applications

Publications (2)

Publication Number Publication Date
WO2007089948A2 WO2007089948A2 (en) 2007-08-09
WO2007089948A3 true WO2007089948A3 (en) 2008-01-17

Family

ID=38328081

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/003207 WO2007089948A2 (en) 2006-02-01 2007-02-01 Improved apparatus and method for injection of fibrin sealant in spinal applications

Country Status (2)

Country Link
US (2) US8419722B2 (en)
WO (1) WO2007089948A2 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8480757B2 (en) 2005-08-26 2013-07-09 Zimmer, Inc. Implants and methods for repair, replacement and treatment of disease
US8497121B2 (en) 2006-12-20 2013-07-30 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
US8518433B2 (en) 2003-12-11 2013-08-27 Zimmer, Inc. Method of treating an osteochondral defect
US9138318B2 (en) 2007-04-12 2015-09-22 Zimmer, Inc. Apparatus for forming an implant

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2248543A1 (en) * 2000-08-24 2010-11-10 Cordis Corporation Fluid delivery systems for delivering fluids to multi-lumen catheters
US7597687B2 (en) * 2004-10-29 2009-10-06 Spinal Restoration, Inc. Injection of fibrin sealant including an anesthetic in spinal applications
US20090324678A1 (en) 2004-07-16 2009-12-31 Spinal Restoration, Inc. Methods and kits for treating joints and soft tissues
US20090181093A1 (en) * 2004-07-16 2009-07-16 Spinal Restoration, Inc. Methods for treating soft tissue damage associated with a surgical procedure
US8206448B2 (en) * 2004-10-29 2012-06-26 Spinal Restoration, Inc. Injection of fibrin sealant using reconstituted components in spinal applications
US20090181092A1 (en) * 2004-07-16 2009-07-16 Spinal Restoration, Inc. Methods for Treating Joints and Discs with a Carrier Matrix and Cells
US20090181892A1 (en) 2004-07-16 2009-07-16 Spinal Restoration, Inc. Methods and kits for treating joints and soft tissues
US20110213464A1 (en) * 2004-10-29 2011-09-01 Whitlock Steven I Injection of fibrin sealant in the absence of corticosteroids in spinal applications
US20090318891A1 (en) * 2006-04-05 2009-12-24 Ronald Marcotte Delivery device, system, and method for delivering substances into blood vessels
US8057426B2 (en) 2007-01-03 2011-11-15 Medtronic Vascular, Inc. Devices and methods for injection of multiple-component therapies
US8343095B2 (en) 2007-02-27 2013-01-01 Regents Of The University Of Minnesota Thermochemical ablation of bodily tissue
EP2034010A1 (en) 2007-08-30 2009-03-11 Omrix Biopharmaceuticals Ltd. Compositions suitable for repair and/or treatment of injured spinal tissue
US8545440B2 (en) 2007-12-21 2013-10-01 Carticept Medical, Inc. Injection system for delivering multiple fluids within the anatomy
WO2009086182A1 (en) 2007-12-21 2009-07-09 Carticept Medical, Inc. Articular injection system
US9044542B2 (en) 2007-12-21 2015-06-02 Carticept Medical, Inc. Imaging-guided anesthesia injection systems and methods
US8197122B2 (en) * 2008-04-24 2012-06-12 Tyco Healthcare Group Lp Dynamic mixing applicator
US8979831B2 (en) * 2008-07-31 2015-03-17 Regents Of The University Of Minnesota Thermochemical ablation system using heat from delivery of electrophiles
US20110202037A1 (en) * 2008-08-18 2011-08-18 Bolger William E Fluid delivery catheter apparatus
US8945142B2 (en) 2008-08-27 2015-02-03 Cook Medical Technologies Llc Delivery system for implanting nasal ventilation tube
EP2334361A4 (en) * 2008-08-27 2011-10-26 Patrick C Melder Nasal ventilation system and method of using same
US8523805B2 (en) * 2008-10-29 2013-09-03 Biomet Biologics, Llc Method and apparatus for containing, transporting, and providing a material
JP5805542B2 (en) * 2009-02-20 2015-11-04 オムリックス・バイオファーマシューティカルズ・リミテッドOmrix Biopharmaceuticals Ltd. Device for administering at least two drugs
US8513259B2 (en) 2009-07-03 2013-08-20 Jdp Therapeutics, Inc. Non-sedating antihistamine injection formulations and methods of use thereof
US8263581B2 (en) 2009-07-03 2012-09-11 Jdp Therapeutics, Inc. Non-sedating antihistamine injection formulations and methods of use thereof
WO2011006056A1 (en) * 2009-07-09 2011-01-13 Ams Research Corporation Multi-chamber cellular mixing and delivery system and method
US9498271B2 (en) * 2009-10-29 2016-11-22 Cook Medical Technologies Llc Coaxial needle cannula with distal spiral mixer and side ports for fluid injection
US8734406B2 (en) 2009-11-24 2014-05-27 Regents Of The University Of Minnesota Methods and systems for chemical ablation
CA2795261C (en) * 2010-04-05 2020-08-25 Neomend, Inc. Method and apparatus for wound sealant application
CA2806755C (en) 2010-07-27 2018-07-10 Richard S. Ginn System for sacro-iliac stabilization
KR101948944B1 (en) * 2010-09-15 2019-02-15 데비오팜 인터네셔날 에스 에이 Method for separating target molecules or particles from fibrinogen-containing samples including blood components
US8360765B2 (en) 2011-01-07 2013-01-29 Covidien Lp Systems and method for forming a coaxial implant
WO2013070692A1 (en) 2011-11-07 2013-05-16 Battelle Memorial Institute Processes for delivery of viscous drug therapies
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
WO2014138226A1 (en) * 2013-03-07 2014-09-12 Allergan, Inc. Double-cartridge syringe for mixing and dispensing adipose tissue with additive
US9867939B2 (en) 2013-03-12 2018-01-16 Allergan, Inc. Adipose tissue combinations, devices, and uses thereof
US9717898B2 (en) 2013-05-06 2017-08-01 Medtronic, Inc. Systems and methods for implanting a medical electrical lead
ES2755986T3 (en) * 2013-05-13 2020-04-24 Univ Arizona Aerostasis in lung surgery
US20140350516A1 (en) 2013-05-23 2014-11-27 Allergan, Inc. Mechanical syringe accessory
WO2015034870A2 (en) * 2013-09-03 2015-03-12 Arocha Max Double-chamber mixing syringe and method of use
US9248384B2 (en) 2013-10-02 2016-02-02 Allergan, Inc. Fat processing system
GB201321078D0 (en) * 2013-11-29 2014-01-15 Smiths Medical Int Ltd Syringe assemblies
US9956384B2 (en) 2014-01-24 2018-05-01 Cook Medical Technologies Llc Articulating balloon catheter and method for using the same
CN106102601B (en) 2014-04-18 2019-01-29 柯惠有限合伙公司 Mixing syringe
CN106102597B (en) * 2014-04-18 2018-12-28 柯惠有限合伙公司 mixing nozzle
US10029048B2 (en) 2014-05-13 2018-07-24 Allergan, Inc. High force injection devices
CN107106152B (en) 2014-09-11 2020-06-05 奥姆里克斯生物药品有限公司 Add-on to medical applicator
US10729456B2 (en) 2014-12-18 2020-08-04 Medtronic, Inc. Systems and methods for deploying an implantable medical electrical lead
CN107530490B (en) 2015-03-10 2021-06-25 爱力根销售有限责任公司 Multi-needle syringe
US20170014569A1 (en) * 2015-07-14 2017-01-19 Boston Scientific Scimed, Inc. Gel delivery catheters, systems, and methods
US10918790B2 (en) 2015-12-22 2021-02-16 Guangzhou Bioseal Biotech Co., Ltd. Dual syringe with funnel feeding kit
USD877890S1 (en) 2015-12-22 2020-03-10 Guangzhou Bioseal Biotech Co., Ltd. Reconstitution device
USD829888S1 (en) 2015-12-22 2018-10-02 Guangzhou Bioseal Biotech Co., Ltd. Reconstitution and delivery device
USD877891S1 (en) 2015-12-22 2020-03-10 Guangzhou Bioseal Biotech Co., Ltd. Reconstitution and delivery device
US11020160B2 (en) * 2016-03-21 2021-06-01 Warsaw Orthopedic, Inc. Surgical injection system and method
CA3016257A1 (en) * 2016-03-28 2017-10-05 Merit Medical Systems, Inc. Inflation device with detachable housing and related methods
AU2017246114B2 (en) 2016-04-08 2022-03-17 Allergan, Inc. Aspiration and injection device
WO2018086699A1 (en) * 2016-11-10 2018-05-17 Lightsens Medical Sa Needle for a syringe, syringe and corresponding control system
EP3823555A1 (en) * 2018-07-19 2021-05-26 Sanulus Medical, LLC Devices and methods for targeted delivery of a substance
US20220346876A1 (en) 2018-07-19 2022-11-03 Sanulus Medical, LLC Devices and methods for targeted delivery of a substance
EP3890652B1 (en) * 2018-12-04 2022-12-28 3M Innovative Properties Company A syringe for storing and dispensing a material
MX2021011881A (en) 2019-03-29 2021-10-26 Innovative Orthopedics Llc Cartilage replacement compositions and methods.
US11771881B2 (en) 2019-08-29 2023-10-03 Toyota Motor Engineering & Manufacturing North America, Inc. Needle adapter and device for soft material extrusion of core-shell structures
CN111588947A (en) * 2020-05-26 2020-08-28 四川大学华西医院 Injection device for stopping bleeding of cervical vertebral canal venous plexus
US20220241152A1 (en) * 2021-02-02 2022-08-04 Freedom Corp. Fibrin biopolymer formation and application device
US20220241521A1 (en) * 2021-02-02 2022-08-04 Freedom Corp. Device for fibrin-biopolymer-forming substance application
GB202108461D0 (en) * 2021-06-14 2021-07-28 Imperial College Innovations Ltd Injection device for injection of biological materials

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4979942A (en) * 1989-10-16 1990-12-25 Johnson & Johnson Medical, Inc. Two component syringe delivery system
US6007515A (en) * 1997-04-14 1999-12-28 Epstein; Gordon Howard Controlled action, manually operable fluid application
US6132396A (en) * 1996-02-06 2000-10-17 Plasmaseal Llc Apparatus for applying tissue sealant
US6620125B1 (en) * 1999-03-19 2003-09-16 Baxter Aktiengesellschaft Method and device for mixing and applying components of differing viscosities
US20050070913A1 (en) * 2003-09-29 2005-03-31 Milbocker Michael T. Devices and methods for spine repair
US20050152889A1 (en) * 2000-06-22 2005-07-14 Spinal Restoration, Inc. Biological boadhesive compositions and methods of preparation and use

Family Cites Families (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2533004A (en) * 1943-10-27 1950-12-05 John D Ferry Fibrin clots and methods for preparing the same
US3089815A (en) * 1951-10-11 1963-05-14 Lieb Hans Injectable pharmaceutical preparation, and a method of making same
JPS56501129A (en) 1979-08-31 1981-08-13
AT366916B (en) * 1980-04-02 1982-05-25 Immuno Ag DEVICE FOR APPLICATING A TISSUE ADHESIVE BASED ON HUMAN OR ANIMAL PROTEINS
US4393041A (en) * 1980-04-25 1983-07-12 International Minerals & Chemical Corp. Fibrin binder/carrier for active biochemical agents
US5264446A (en) 1980-09-09 1993-11-23 Bayer Aktiengesellschaft Solid medicament formulations containing nifedipine, and processes for their preparation
DE3037270A1 (en) 1980-10-02 1982-05-19 Ulatowski, Lothar, Dr.med., 5630 Remscheid Fibrin-antibiotic composite chain - for use as an antiseptic implant
EP0068149A3 (en) 1981-06-25 1983-07-20 Serapharm GmbH & Co. KG Dry preparation containing fibrinogene, its production and use
ATE20824T1 (en) * 1981-06-25 1986-08-15 Serapharm Gmbh & Co Kg ENRICHED PLASMA DERIVES TO SUPPORT WOUND CLOSURE AND HEALING.
US4442655A (en) * 1981-06-25 1984-04-17 Serapharm Michael Stroetmann Fibrinogen-containing dry preparation, manufacture and use thereof
US4619913A (en) * 1984-05-29 1986-10-28 Matrix Pharmaceuticals, Inc. Treatments employing drug-containing matrices for introduction into cellular lesion areas
US5080648A (en) * 1987-06-08 1992-01-14 Antonio Nicholas F D Hypodermic fluid dispenser
DE3725552A1 (en) * 1987-08-01 1989-02-09 Hoechst Ag SPRAY HEAD TO APPLY A MULTI-COMPONENT MATERIAL BY GAS
US5290552A (en) * 1988-05-02 1994-03-01 Matrix Pharmaceutical, Inc./Project Hear Surgical adhesive material
US5124155A (en) * 1988-06-21 1992-06-23 Chiron Ophthalmics, Inc. Fibronectin wound-healing dressings
US6117425A (en) * 1990-11-27 2000-09-12 The American National Red Cross Supplemented and unsupplemented tissue sealants, method of their production and use
US6197325B1 (en) * 1990-11-27 2001-03-06 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6054122A (en) * 1990-11-27 2000-04-25 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6559119B1 (en) * 1990-11-27 2003-05-06 Loyola University Of Chicago Method of preparing a tissue sealant-treated biomedical material
SE9101853D0 (en) 1991-06-17 1991-06-17 Jonas Wadstroem IMPROVED TISSUE ASHESIVE
US5226446A (en) * 1991-06-25 1993-07-13 Eaton Corporation Flow noise reduction
US5370273A (en) * 1991-10-16 1994-12-06 Minnesota Mining And Manufacturing Company Multi-component applicator assembly
CN1091315A (en) * 1992-10-08 1994-08-31 E·R·斯奎布父子公司 Fibrin sealant compositions and using method thereof
AU696691C (en) 1993-03-12 2003-09-18 American National Red Cross, The Supplemented and unsupplemented tissue sealants, methods of their production and use
WO1995001133A1 (en) * 1993-06-30 1995-01-12 Baxter International Inc. Vial adapter
ATE241340T1 (en) * 1994-02-17 2003-06-15 New York Blood Ct Inc BIOLOGICAL BIOADHESIVE PREPARATIONS CONTAINING FIBRIN ADHESIVES AND LIPOSOMES, METHOD FOR THEIR PRODUCTION AND USE
CA2197679C (en) * 1994-08-17 2007-09-11 Patrik Luescher Implant, and method and device for inserting the implant
WO1996017633A1 (en) 1994-12-07 1996-06-13 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US5643192A (en) * 1995-04-06 1997-07-01 Hamilton Civic Hospitals Research Development, Inc. Autologous fibrin glue and methods for its preparation and use
WO1996041818A1 (en) * 1995-06-09 1996-12-27 Drohan William N Chitin hydrogels, methods of their production and use
HUP9700322A3 (en) * 1995-06-09 2001-03-28 Euro Celtique Sa Formulations and methods for providing prolonged local anesthesia
US5980504A (en) * 1996-08-13 1999-11-09 Oratec Interventions, Inc. Method for manipulating tissue of an intervertebral disc
US6007570A (en) 1996-08-13 1999-12-28 Oratec Interventions, Inc. Apparatus with functional element for performing function upon intervertebral discs
US5702715A (en) * 1995-10-27 1997-12-30 Drying Technology Reinforced biological sealants
US5925738A (en) * 1995-12-01 1999-07-20 The American National Red Cross Methods of production and use of liquid formulations of plasma proteins
US6320029B1 (en) * 1996-11-29 2001-11-20 The American National Red Cross Methods of production and use of liquid formulations of plasma proteins
USRE38431E1 (en) * 1995-12-01 2004-02-17 The American National Red Cross Methods of production and use of liquid formulations of plasma proteins
EP0835667B1 (en) * 1996-03-15 2005-11-09 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Spray device for applying tissue adhesive
WO1997042986A1 (en) 1996-05-14 1997-11-20 C. R. Bard, Inc. Methods and products for sealing a fluid leak in a tissue
US6733496B2 (en) * 2001-06-06 2004-05-11 Oratec Interventions, Inc. Intervertebral disc device employing flexible probe
US6726685B2 (en) * 2001-06-06 2004-04-27 Oratec Interventions, Inc. Intervertebral disc device employing looped probe
US6126682A (en) * 1996-08-13 2000-10-03 Oratec Interventions, Inc. Method for treating annular fissures in intervertebral discs
US6733472B1 (en) * 1997-04-14 2004-05-11 Baxter International Inc. Sealant applicator tip and application method
US6007811A (en) * 1997-07-01 1999-12-28 Sea Run Holdings, Inc. Method of producing fibrin sealant from clotting factors in fish blood
CA2308462C (en) * 1997-11-17 2009-02-24 Haemacure Corporation Fibrin sealants or adhesives comprising a hyaluronic acid derivative material
US6079868A (en) * 1997-12-18 2000-06-27 Advanced Bio Surfaces, Inc. Static mixer
CA2314900C (en) * 1997-12-19 2009-02-24 United States Surgical Corporation Fibrin mixture and dispenser assembly
US6762336B1 (en) * 1998-01-19 2004-07-13 The American National Red Cross Hemostatic sandwich bandage
AU3104999A (en) * 1998-03-19 1999-10-11 Oratec Interventions, Inc. Catheter for delivery of energy to a surgical site
US6780411B2 (en) * 1998-05-01 2004-08-24 Zymogenetics, Inc. Tissue sealant compositions
US6224630B1 (en) * 1998-05-29 2001-05-01 Advanced Bio Surfaces, Inc. Implantable tissue repair device
US6428527B1 (en) * 1998-11-10 2002-08-06 Becton, Dickinson And Company Method for coating a blood collection device
US7449019B2 (en) * 1999-01-25 2008-11-11 Smith & Nephew, Inc. Intervertebral decompression
US6183518B1 (en) * 1999-02-22 2001-02-06 Anthony C. Ross Method of replacing nucleus pulposus and repairing the intervertebral disk
DE19910972C1 (en) * 1999-03-09 2000-10-26 Omrix Biopharm Sa Device for applying a flowable medium, in particular a tissue adhesive
US6428576B1 (en) 1999-04-16 2002-08-06 Endospine, Ltd. System for repairing inter-vertebral discs
US6554851B1 (en) * 1999-05-07 2003-04-29 Scimed Life Systems, Inc. Methods of sealing an injection site
US6648920B2 (en) * 1999-10-08 2003-11-18 Bret A. Ferree Natural and synthetic supplements to engineered annulus and disc tissues
ES2428025T3 (en) * 2000-04-28 2013-11-05 Cirque Medical Incorporated Intravenous multilumen extension
WO2001097872A1 (en) 2000-06-22 2001-12-27 Austin Sam L Bioadhesive compositions and methods of preparation and use
US20020045668A1 (en) * 2000-07-17 2002-04-18 Wenbin Dang Compositions for sustained release of analgesic agents, and methods of making and using the same
US6506365B1 (en) * 2000-09-25 2003-01-14 Baxter Aktiengesellschaft Fibrin/fibrinogen binding conjugate
US6695839B2 (en) * 2001-02-08 2004-02-24 Oratec Interventions, Inc. Method and apparatus for treatment of disrupted articular cartilage
GB2374014A (en) * 2001-04-02 2002-10-09 Cambridge Consultants Biological sealant storage and dispensing system
US6638276B2 (en) * 2001-06-06 2003-10-28 Oratec Interventions, Inc. Intervertebral disc device employing prebent sheath
US7455657B2 (en) * 2001-06-19 2008-11-25 Boston Scientific Scimed, Inc Method and apparatus to modify a fluid using a selectively permeable membrane
US20030091558A1 (en) * 2001-10-03 2003-05-15 Woolverton Christopher J. Storage-stable fibrinogen solutions
EP1448089A4 (en) 2001-11-01 2008-06-04 Spine Wave Inc Devices and methods for the restoration of a spinal disc
US6972005B2 (en) * 2002-05-10 2005-12-06 Boehm Jr Frank H Dual chamber syringe and dual lumen needle
WO2004060425A2 (en) * 2002-12-27 2004-07-22 Angiotech International Ag Compositions and methods of using collagen and mmpi
US7004971B2 (en) * 2002-12-31 2006-02-28 Depuy Acromed, Inc. Annular nucleus pulposus replacement
US6884232B1 (en) * 2003-10-31 2005-04-26 Baxter International Inc. Laparoscopic spray device and method of use
US8088228B2 (en) * 2010-04-28 2012-01-03 Cook Medical Technologies Llc Method and system for cleaning fluid reservoir of vascular access device

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4979942A (en) * 1989-10-16 1990-12-25 Johnson & Johnson Medical, Inc. Two component syringe delivery system
US6132396A (en) * 1996-02-06 2000-10-17 Plasmaseal Llc Apparatus for applying tissue sealant
US6007515A (en) * 1997-04-14 1999-12-28 Epstein; Gordon Howard Controlled action, manually operable fluid application
US6620125B1 (en) * 1999-03-19 2003-09-16 Baxter Aktiengesellschaft Method and device for mixing and applying components of differing viscosities
US20050152889A1 (en) * 2000-06-22 2005-07-14 Spinal Restoration, Inc. Biological boadhesive compositions and methods of preparation and use
US20050070913A1 (en) * 2003-09-29 2005-03-31 Milbocker Michael T. Devices and methods for spine repair

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8518433B2 (en) 2003-12-11 2013-08-27 Zimmer, Inc. Method of treating an osteochondral defect
US8524268B2 (en) 2003-12-11 2013-09-03 Zimmer, Inc. Cadaveric allogenic human juvenile cartilage implant
US8652507B2 (en) 2003-12-11 2014-02-18 Zimmer, Inc. Juvenile cartilage composition
US8765165B2 (en) 2003-12-11 2014-07-01 Zimmer, Inc. Particulate cartilage system
US8784863B2 (en) 2003-12-11 2014-07-22 Zimmer, Inc. Particulate cadaveric allogenic cartilage system
US8834914B2 (en) 2003-12-11 2014-09-16 Zimmer, Inc. Treatment methods using a particulate cadaveric allogenic juvenile cartilage particles
US8480757B2 (en) 2005-08-26 2013-07-09 Zimmer, Inc. Implants and methods for repair, replacement and treatment of disease
US8497121B2 (en) 2006-12-20 2013-07-30 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
US9138318B2 (en) 2007-04-12 2015-09-22 Zimmer, Inc. Apparatus for forming an implant

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