WO2007089883A3 - Nanoparticle coating of surfaces - Google Patents

Nanoparticle coating of surfaces Download PDF

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Publication number
WO2007089883A3
WO2007089883A3 PCT/US2007/002720 US2007002720W WO2007089883A3 WO 2007089883 A3 WO2007089883 A3 WO 2007089883A3 US 2007002720 W US2007002720 W US 2007002720W WO 2007089883 A3 WO2007089883 A3 WO 2007089883A3
Authority
WO
WIPO (PCT)
Prior art keywords
drug
nanoparticle coating
hydrogel
coating
capillary
Prior art date
Application number
PCT/US2007/002720
Other languages
French (fr)
Other versions
WO2007089883A2 (en
Inventor
Robert A Hoerr
John V Carlson
Original Assignee
Nanocopoeia Inc
Robert A Hoerr
John V Carlson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanocopoeia Inc, Robert A Hoerr, John V Carlson filed Critical Nanocopoeia Inc
Priority to CA2641117A priority Critical patent/CA2641117C/en
Priority to EP07762706A priority patent/EP1988941A2/en
Publication of WO2007089883A2 publication Critical patent/WO2007089883A2/en
Publication of WO2007089883A3 publication Critical patent/WO2007089883A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/085—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • G—PHYSICS
    • G02—OPTICS
    • G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00—Optical parts
    • G02C7/02—Lenses; Lens systems ; Methods of designing lenses
    • G02C7/04—Contact lenses for the eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/62—Encapsulated active agents, e.g. emulsified droplets
    • A61L2300/624—Nanocapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
    • B05B5/03—Discharge apparatus, e.g. electrostatic spray guns characterised by the use of gas, e.g. electrostatically assisted pneumatic spraying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/08—Plant for applying liquids or other fluent materials to objects
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
    • B05B7/02—Spray pistols; Apparatus for discharge
    • B05B7/06—Spray pistols; Apparatus for discharge with at least one outlet orifice surrounding another approximately in the same plane
    • B05B7/061—Spray pistols; Apparatus for discharge with at least one outlet orifice surrounding another approximately in the same plane with several liquid outlets discharging one or several liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D1/00—Processes for applying liquids or other fluent materials
    • B05D1/02—Processes for applying liquids or other fluent materials performed by spraying
    • B05D1/04—Processes for applying liquids or other fluent materials performed by spraying involving the use of an electrostatic field
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D1/00—Processes for applying liquids or other fluent materials
    • B05D1/02—Processes for applying liquids or other fluent materials performed by spraying
    • B05D1/04—Processes for applying liquids or other fluent materials performed by spraying involving the use of an electrostatic field
    • B05D1/06—Applying particulate materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D2258/00—Small objects (e.g. screws)
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D2451/00—Type of carrier, type of coating (Multilayers)

Abstract

A nanoparticle coated hydrogel may be formed by a method of electrospraying nanoparticles on to a hydrogel surface includes providing a drug and polymer combination in solvent to an inner capillary of a coaxial capillary spray nozzle. A coating with a drug that releases over time may be provided. Open and closed matrixes may be selectively formed to help modify time release periods.
PCT/US2007/002720 2006-01-31 2007-01-31 Nanoparticle coating of surfaces WO2007089883A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA2641117A CA2641117C (en) 2006-01-31 2007-01-31 Nanoparticle coating of surfaces
EP07762706A EP1988941A2 (en) 2006-01-31 2007-01-31 Nanoparticle coating of surfaces

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US76422906P 2006-01-31 2006-01-31
US60/764,229 2006-01-31
US83870806P 2006-08-18 2006-08-18
US60/838,708 2006-08-18

Publications (2)

Publication Number Publication Date
WO2007089883A2 WO2007089883A2 (en) 2007-08-09
WO2007089883A3 true WO2007089883A3 (en) 2007-11-15

Family

ID=38326884

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/002720 WO2007089883A2 (en) 2006-01-31 2007-01-31 Nanoparticle coating of surfaces

Country Status (4)

Country Link
US (1) US9248217B2 (en)
EP (2) EP1988941A2 (en)
CA (1) CA2641117C (en)
WO (1) WO2007089883A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9108217B2 (en) 2006-01-31 2015-08-18 Nanocopoeia, Inc. Nanoparticle coating of surfaces
US9248217B2 (en) 2006-01-31 2016-02-02 Nanocopocia, LLC Nanoparticle coating of surfaces

Families Citing this family (126)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6302875B1 (en) 1996-10-11 2001-10-16 Transvascular, Inc. Catheters and related devices for forming passageways between blood vessels or other anatomical structures
US6433154B1 (en) 1997-06-12 2002-08-13 Bristol-Myers Squibb Company Functional receptor/kinase chimera in yeast cells
EP1282470B1 (en) 2000-05-16 2008-08-20 Regents Of The University Of Minnesota High mass throughput particle generation using multiple nozzle spraying
US7247338B2 (en) 2001-05-16 2007-07-24 Regents Of The University Of Minnesota Coating medical devices
US20070129761A1 (en) 2002-04-08 2007-06-07 Ardian, Inc. Methods for treating heart arrhythmia
US7756583B2 (en) 2002-04-08 2010-07-13 Ardian, Inc. Methods and apparatus for intravascularly-induced neuromodulation
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US7617005B2 (en) 2002-04-08 2009-11-10 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US9636174B2 (en) 2002-04-08 2017-05-02 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US8347891B2 (en) 2002-04-08 2013-01-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen
US20080213331A1 (en) 2002-04-08 2008-09-04 Ardian, Inc. Methods and devices for renal nerve blocking
US20070135875A1 (en) 2002-04-08 2007-06-14 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
DE202004021944U1 (en) 2003-09-12 2013-07-16 Vessix Vascular, Inc. Selectable eccentric remodeling and / or ablation of atherosclerotic material
US9974607B2 (en) 2006-10-18 2018-05-22 Vessix Vascular, Inc. Inducing desirable temperature effects on body tissue
US9713730B2 (en) 2004-09-10 2017-07-25 Boston Scientific Scimed, Inc. Apparatus and method for treatment of in-stent restenosis
US8396548B2 (en) * 2008-11-14 2013-03-12 Vessix Vascular, Inc. Selective drug delivery in a lumen
WO2006063199A2 (en) 2004-12-09 2006-06-15 The Foundry, Inc. Aortic valve repair
WO2007089881A2 (en) * 2006-01-31 2007-08-09 Regents Of The University Of Minnesota Electrospray coating of objects
US8019435B2 (en) 2006-05-02 2011-09-13 Boston Scientific Scimed, Inc. Control of arterial smooth muscle tone
EP2455036B1 (en) 2006-10-18 2015-07-15 Vessix Vascular, Inc. Tuned RF energy and electrical tissue characterization for selective treatment of target tissues
CA2666663C (en) 2006-10-18 2016-02-09 Minnow Medical, Inc. System for inducing desirable temperature effects on body tissue
EP2111305A2 (en) * 2007-01-31 2009-10-28 Nanocopoeia, Inc. Nanoparticle coating of surfaces
US8496653B2 (en) 2007-04-23 2013-07-30 Boston Scientific Scimed, Inc. Thrombus removal
US8277867B2 (en) * 2007-09-14 2012-10-02 Boston Scientific Scimed, Inc. Microdrop ablumenal coating system and method
US20090104240A1 (en) * 2007-10-19 2009-04-23 Abbott Cardiovascular Systems Inc. Dual Drug Formulations For Implantable Medical Devices For Treatment of Vascular Diseases
KR100919772B1 (en) 2007-12-24 2009-10-07 연세대학교 산학협력단 Method and Apparatus for Producing Polymer Core-shell Microcapsules by Electrospraying
FR2926466B1 (en) * 2008-01-23 2010-11-12 Dbv Tech METHOD FOR MANUFACTURING PATCHES BY ELECTROSPRAY
US8293337B2 (en) * 2008-06-23 2012-10-23 Cornell University Multiplexed electrospray deposition method
WO2010056745A1 (en) 2008-11-17 2010-05-20 Minnow Medical, Inc. Selective accumulation of energy with or without knowledge of tissue topography
US8551096B2 (en) 2009-05-13 2013-10-08 Boston Scientific Scimed, Inc. Directional delivery of energy and bioactives
KR20130108067A (en) 2010-04-09 2013-10-02 베식스 바스큘라 인코포레이티드 Power generating and control apparatus for the treatment of tissue
US9192790B2 (en) 2010-04-14 2015-11-24 Boston Scientific Scimed, Inc. Focused ultrasonic renal denervation
US20110262654A1 (en) * 2010-04-26 2011-10-27 Yates Mathew Z Process for preparing polymer particles containing metallic flakes
US8473067B2 (en) 2010-06-11 2013-06-25 Boston Scientific Scimed, Inc. Renal denervation and stimulation employing wireless vascular energy transfer arrangement
US9358365B2 (en) 2010-07-30 2016-06-07 Boston Scientific Scimed, Inc. Precision electrode movement control for renal nerve ablation
US9155589B2 (en) 2010-07-30 2015-10-13 Boston Scientific Scimed, Inc. Sequential activation RF electrode set for renal nerve ablation
US9408661B2 (en) 2010-07-30 2016-08-09 Patrick A. Haverkost RF electrodes on multiple flexible wires for renal nerve ablation
US9463062B2 (en) 2010-07-30 2016-10-11 Boston Scientific Scimed, Inc. Cooled conductive balloon RF catheter for renal nerve ablation
US9084609B2 (en) 2010-07-30 2015-07-21 Boston Scientific Scime, Inc. Spiral balloon catheter for renal nerve ablation
US8974451B2 (en) 2010-10-25 2015-03-10 Boston Scientific Scimed, Inc. Renal nerve ablation using conductive fluid jet and RF energy
US9220558B2 (en) 2010-10-27 2015-12-29 Boston Scientific Scimed, Inc. RF renal denervation catheter with multiple independent electrodes
US9028485B2 (en) 2010-11-15 2015-05-12 Boston Scientific Scimed, Inc. Self-expanding cooling electrode for renal nerve ablation
US9089350B2 (en) 2010-11-16 2015-07-28 Boston Scientific Scimed, Inc. Renal denervation catheter with RF electrode and integral contrast dye injection arrangement
US9668811B2 (en) 2010-11-16 2017-06-06 Boston Scientific Scimed, Inc. Minimally invasive access for renal nerve ablation
US9326751B2 (en) 2010-11-17 2016-05-03 Boston Scientific Scimed, Inc. Catheter guidance of external energy for renal denervation
US9060761B2 (en) 2010-11-18 2015-06-23 Boston Scientific Scime, Inc. Catheter-focused magnetic field induced renal nerve ablation
US9192435B2 (en) 2010-11-22 2015-11-24 Boston Scientific Scimed, Inc. Renal denervation catheter with cooled RF electrode
US9023034B2 (en) 2010-11-22 2015-05-05 Boston Scientific Scimed, Inc. Renal ablation electrode with force-activatable conduction apparatus
US20120157993A1 (en) 2010-12-15 2012-06-21 Jenson Mark L Bipolar Off-Wall Electrode Device for Renal Nerve Ablation
EP2665559B1 (en) 2011-01-19 2018-07-18 Washington University Electrohydrodynamic atomization nozzle emitting a liquid sheet
US9220561B2 (en) 2011-01-19 2015-12-29 Boston Scientific Scimed, Inc. Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury
WO2012161875A1 (en) 2011-04-08 2012-11-29 Tyco Healthcare Group Lp Iontophoresis drug delivery system and method for denervation of the renal sympathetic nerve and iontophoretic drug delivery
WO2012148969A2 (en) 2011-04-25 2012-11-01 Brian Kelly Apparatus and methods related to constrained deployment of cryogenic balloons for limited cryogenic ablation of vessel walls
WO2013013156A2 (en) 2011-07-20 2013-01-24 Boston Scientific Scimed, Inc. Percutaneous devices and methods to visualize, target and ablate nerves
JP6106669B2 (en) 2011-07-22 2017-04-05 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． A neuromodulation system having a neuromodulation element that can be placed in a helical guide
EP2765942B1 (en) 2011-10-10 2016-02-24 Boston Scientific Scimed, Inc. Medical devices including ablation electrodes
EP2765940B1 (en) 2011-10-11 2015-08-26 Boston Scientific Scimed, Inc. Off-wall electrode device for nerve modulation
US9420955B2 (en) 2011-10-11 2016-08-23 Boston Scientific Scimed, Inc. Intravascular temperature monitoring system and method
US9364284B2 (en) 2011-10-12 2016-06-14 Boston Scientific Scimed, Inc. Method of making an off-wall spacer cage
EP2768563B1 (en) 2011-10-18 2016-11-09 Boston Scientific Scimed, Inc. Deflectable medical devices
EP2768568B1 (en) 2011-10-18 2020-05-06 Boston Scientific Scimed, Inc. Integrated crossing balloon catheter
WO2013070724A1 (en) 2011-11-08 2013-05-16 Boston Scientific Scimed, Inc. Ostial renal nerve ablation
EP2779929A1 (en) 2011-11-15 2014-09-24 Boston Scientific Scimed, Inc. Device and methods for renal nerve modulation monitoring
US9119632B2 (en) 2011-11-21 2015-09-01 Boston Scientific Scimed, Inc. Deflectable renal nerve ablation catheter
US9265969B2 (en) 2011-12-21 2016-02-23 Cardiac Pacemakers, Inc. Methods for modulating cell function
WO2013096920A1 (en) 2011-12-23 2013-06-27 Vessix Vascular, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
WO2013101452A1 (en) 2011-12-28 2013-07-04 Boston Scientific Scimed, Inc. Device and methods for nerve modulation using a novel ablation catheter with polymeric ablative elements
US9050106B2 (en) 2011-12-29 2015-06-09 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
US10660703B2 (en) 2012-05-08 2020-05-26 Boston Scientific Scimed, Inc. Renal nerve modulation devices
US10321946B2 (en) 2012-08-24 2019-06-18 Boston Scientific Scimed, Inc. Renal nerve modulation devices with weeping RF ablation balloons
CN104780859B (en) 2012-09-17 2017-07-25 波士顿科学西美德公司 Self-positioning electrode system and method for renal regulation
US10398464B2 (en) 2012-09-21 2019-09-03 Boston Scientific Scimed, Inc. System for nerve modulation and innocuous thermal gradient nerve block
US10549127B2 (en) 2012-09-21 2020-02-04 Boston Scientific Scimed, Inc. Self-cooling ultrasound ablation catheter
CN104869930B (en) 2012-10-10 2020-12-25 波士顿科学国际有限公司 Renal neuromodulation apparatus and methods
US9392805B2 (en) * 2013-01-16 2016-07-19 1,4 Group, Inc. Methods for applying a liquid crop-preservative formulation to a container
US9693821B2 (en) 2013-03-11 2017-07-04 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
WO2014163987A1 (en) 2013-03-11 2014-10-09 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9808311B2 (en) 2013-03-13 2017-11-07 Boston Scientific Scimed, Inc. Deflectable medical devices
EP2967734B1 (en) 2013-03-15 2019-05-15 Boston Scientific Scimed, Inc. Methods and apparatuses for remodeling tissue of or adjacent to a body passage
WO2014149690A2 (en) 2013-03-15 2014-09-25 Boston Scientific Scimed, Inc. Medical devices and methods for treatment of hypertension that utilize impedance compensation
EP4233991A1 (en) 2013-03-15 2023-08-30 Medtronic Ardian Luxembourg S.à.r.l. Controlled neuromodulation systems
US10265122B2 (en) 2013-03-15 2019-04-23 Boston Scientific Scimed, Inc. Nerve ablation devices and related methods of use
KR101397384B1 (en) * 2013-03-28 2014-05-20 엔젯 주식회사 Spray nozzle and system for coating for the same
US20140327427A1 (en) * 2013-05-03 2014-11-06 Clinton Instrument Company Coating defect detection apparatus and method for cut-to-length catheter shafts
US20140356900A1 (en) * 2013-05-31 2014-12-04 Empire Technology Development Llc Detection of luminal urinary catheter colonization
JP2016523147A (en) 2013-06-21 2016-08-08 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． Renal denervation balloon catheter with a riding-type electrode support
CN105473092B (en) 2013-06-21 2019-05-17 波士顿科学国际有限公司 The medical instrument for renal nerve ablation with rotatable shaft
US9707036B2 (en) 2013-06-25 2017-07-18 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation using localized indifferent electrodes
AU2014284558B2 (en) 2013-07-01 2017-08-17 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
WO2015006573A1 (en) 2013-07-11 2015-01-15 Boston Scientific Scimed, Inc. Medical device with stretchable electrode assemblies
US10660698B2 (en) 2013-07-11 2020-05-26 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation
CN105682594B (en) 2013-07-19 2018-06-22 波士顿科学国际有限公司 Helical bipolar electrodes renal denervation dominates air bag
JP6122217B2 (en) 2013-07-22 2017-04-26 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． Renal nerve ablation medical device
EP3024406B1 (en) 2013-07-22 2019-06-19 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
US9744542B2 (en) * 2013-07-29 2017-08-29 Apeel Technology, Inc. Agricultural skin grafting
US10722300B2 (en) 2013-08-22 2020-07-28 Boston Scientific Scimed, Inc. Flexible circuit having improved adhesion to a renal nerve modulation balloon
EP3041425B1 (en) 2013-09-04 2022-04-13 Boston Scientific Scimed, Inc. Radio frequency (rf) balloon catheter having flushing and cooling capability
WO2015038947A1 (en) 2013-09-13 2015-03-19 Boston Scientific Scimed, Inc. Ablation balloon with vapor deposited cover layer
US11246654B2 (en) 2013-10-14 2022-02-15 Boston Scientific Scimed, Inc. Flexible renal nerve ablation devices and related methods of use and manufacture
CN105592778B (en) 2013-10-14 2019-07-23 波士顿科学医学有限公司 High-resolution cardiac mapping electrod-array conduit
US9770606B2 (en) 2013-10-15 2017-09-26 Boston Scientific Scimed, Inc. Ultrasound ablation catheter with cooling infusion and centering basket
CN105636537B (en) 2013-10-15 2018-08-17 波士顿科学国际有限公司 Medical instrument sacculus
WO2015057961A1 (en) 2013-10-18 2015-04-23 Boston Scientific Scimed, Inc. Balloon catheters with flexible conducting wires and related methods of use and manufacture
WO2015061457A1 (en) 2013-10-25 2015-04-30 Boston Scientific Scimed, Inc. Embedded thermocouple in denervation flex circuit
JP6382989B2 (en) 2014-01-06 2018-08-29 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． Medical device with tear resistant flexible circuit assembly
CN106572881B (en) 2014-02-04 2019-07-26 波士顿科学国际有限公司 Substitution of the heat sensor on bipolar electrode is placed
US11000679B2 (en) 2014-02-04 2021-05-11 Boston Scientific Scimed, Inc. Balloon protection and rewrapping devices and related methods of use
US10654056B1 (en) * 2014-04-06 2020-05-19 Clearist Inc. Charge assisted spray deposition method and apparatus
US10709490B2 (en) 2014-05-07 2020-07-14 Medtronic Ardian Luxembourg S.A.R.L. Catheter assemblies comprising a direct heating element for renal neuromodulation and associated systems and methods
US9573144B2 (en) 2014-05-30 2017-02-21 Taiwan Semiconductor Manufacturing Co., Ltd. Coating apparatus and method of forming coating film
KR101521552B1 (en) * 2014-06-30 2015-05-19 경북대학교 산학협력단 Bio-device using polymer film with polymer particle, and preparation method thereof
CN107709349B (en) 2015-05-20 2022-01-28 阿比尔技术公司 Plant extract composition and method for preparing the same
EP3349589B1 (en) 2015-09-16 2022-12-14 Apeel Technology, Inc. Method for forming a protective coating by applying fatty acid glyceride compounds to a surface
EP3386303B1 (en) 2015-12-10 2020-03-11 Apeel Technology, Inc. Process for depolymerising cutin
EP3407713A1 (en) 2016-01-26 2018-12-05 Apeel Technology, Inc. Method for preparing and preserving sanitized products
CN110087475B (en) 2016-11-17 2023-04-11 阿比尔技术公司 Composition comprising plant extracts and its preparation method
US11084100B2 (en) * 2017-08-23 2021-08-10 University Of Central Florida Research Foundation, Inc. Laser-assisted manufacturing system and associated method of use
US11116561B2 (en) 2018-01-24 2021-09-14 Medtronic Ardian Luxembourg S.A.R.L. Devices, agents, and associated methods for selective modulation of renal nerves
EP4054352A1 (en) * 2019-11-04 2022-09-14 Cannabis Global, Inc, Electrosprayed and electrospun cannabinoid compositions and process to produce
WO2021150981A1 (en) 2020-01-24 2021-07-29 Nanocopoeia, Llc Amorphous solid dispersions of dasatinib and uses thereof
CA3168680A1 (en) 2020-01-31 2021-08-05 Nanocopoeia, Llc Amorphous nilotinib microparticles and uses thereof
CN115443066A (en) 2020-03-04 2022-12-06 阿比尔技术公司 Coated agricultural products and corresponding method
CA3181361A1 (en) 2020-04-30 2021-11-04 Nanocopoeia, Llc Orally disintegrating tablet comprising amorphous solid dispersion of nilotinib
GB202008098D0 (en) 2020-05-29 2020-07-15 Uea Enterprises Ltd A method of coating an ocular prosthetic device and other prosthetics
KR102649715B1 (en) * 2020-10-30 2024-03-21 세메스 주식회사 Surface treatment apparatus and surface treatment method
JP2023548012A (en) 2020-10-30 2023-11-15 アピール テクノロジー，インコーポレイテッド Composition and method for its preparation

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5873523A (en) * 1996-02-29 1999-02-23 Yale University Electrospray employing corona-assisted cone-jet mode
US20020007869A1 (en) * 2000-05-16 2002-01-24 Pui David Y.H. High mass throughput particle generation using multiple nozzle spraying
US20020065553A1 (en) * 2000-11-28 2002-05-30 Scimed Life System, Inc. Method for manufacturing a medical device having a coated portion by laser ablation
US20030143315A1 (en) * 2001-05-16 2003-07-31 Pui David Y H Coating medical devices
WO2005074913A2 (en) * 2004-01-30 2005-08-18 Angiotech International Ag Compositions and methods for treating contracture

Family Cites Families (145)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3521125A (en) 1967-01-16 1970-07-21 Robert H Nelson Electrostatic crop dusting apparatus
US4002777A (en) 1967-10-25 1977-01-11 Ransburg Corporation Method of depositing electrostatically charged liquid coating material
CH496481A (en) 1969-06-25 1970-09-30 Gema Ag App Bau Device for the electrostatic coating of objects with atomized solid particles
US3654534A (en) 1971-02-09 1972-04-04 Ronald S Fischer Air neutralization
US4328940A (en) 1972-12-14 1982-05-11 Electrogasdynamics, Inc. Method of electrostatically enhancing deposition of air borne spray materials
US3905330A (en) 1973-11-21 1975-09-16 Ronald Alan Coffee Electrostatic deposition of particles
FR2283729A1 (en) 1974-09-06 1976-04-02 Air Ind ELECTROSTATIC PROJECTION NOZZLE FOR POWDERED PRODUCTS
IE45426B1 (en) 1976-07-15 1982-08-25 Ici Ltd Atomisation of liquids
US4265641A (en) 1979-05-18 1981-05-05 Monsanto Company Method and apparatus for particle charging and particle collecting
GB2075759B (en) 1980-03-27 1984-10-03 Masuda Senichi Particle charging apparatus
ATE29225T1 (en) 1982-08-25 1987-09-15 Ici Plc PUMP WITH ELECTROSTATIC DRIVE EFFECT FOR SPRAYING SYSTEM.
NZ209210A (en) 1983-08-18 1988-04-29 Ici Plc Electrostatic sprayhead atomises aqueous liquids
JPS60183067A (en) 1984-03-02 1985-09-18 Honda Motor Co Ltd Painting method
IE58110B1 (en) 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US5100792A (en) 1984-11-13 1992-03-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US5036006A (en) 1984-11-13 1991-07-30 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US5091204A (en) * 1985-08-23 1992-02-25 Weshington Research Foundation Polymeric intraocular lens material having improved surface properties
GB8604328D0 (en) 1986-02-21 1986-03-26 Ici Plc Producing spray of droplets of liquid
GB8609703D0 (en) 1986-04-21 1986-05-29 Ici Plc Electrostatic spraying
US4748043A (en) 1986-08-29 1988-05-31 Minnesota Mining And Manufacturing Company Electrospray coating process
US5120657A (en) 1986-12-05 1992-06-09 Agracetus, Inc. Apparatus for genetic transformation
IL84459A (en) 1986-12-05 1993-07-08 Agracetus Apparatus and method for the injection of carrier particles carrying genetic material into living cells
US4749125A (en) 1987-01-16 1988-06-07 Terronics Development Corp. Nozzle method and apparatus
US5179022A (en) 1988-02-29 1993-01-12 E. I. Du Pont De Nemours & Co. Biolistic apparatus for delivering substances into cells and tissues in a non-lethal manner
US4946899A (en) 1988-12-16 1990-08-07 The University Of Akron Thermoplastic elastomers of isobutylene and process of preparation
US5091205A (en) 1989-01-17 1992-02-25 Union Carbide Chemicals & Plastics Technology Corporation Hydrophilic lubricious coatings
US5000978A (en) 1989-06-29 1991-03-19 The Procter & Gamble Company Electrostatic coating of detergent granules
US5141131A (en) 1989-06-30 1992-08-25 Dowelanco Method and apparatus for the acceleration of a propellable matter
AU642889B2 (en) 1989-07-11 1993-11-04 Biotechnology Research And Development Corporation Aerosol beam microinjector
US5240842A (en) 1989-07-11 1993-08-31 Biotechnology Research And Development Corporation Aerosol beam microinjector
AU6964191A (en) 1989-11-16 1991-06-13 Cornell Research Foundation Inc. Particle-mediated transformation of animal tissue cells
GB8926281D0 (en) 1989-11-21 1990-01-10 Du Pont Improvements in or relating to radiation sensitive devices
US5044564A (en) 1989-11-21 1991-09-03 Sickles James E Electrostatic spray gun
ES2079467T3 (en) 1989-12-19 1996-01-16 Ciba Geigy Ag PROCEDURE AND DEVICE FOR THE GENETIC TRANSFORMATION OF CELLS.
CN1052695A (en) 1989-12-22 1991-07-03 中国科学院生物物理研究所 A kind of method of metastatic gene and the particle gun of metastatic gene thereof
US5066587A (en) 1990-01-26 1991-11-19 The Upjohn Company Gas driven microprojectile accelerator and method of use
US5204253A (en) 1990-05-29 1993-04-20 E. I. Du Pont De Nemours And Company Method and apparatus for introducing biological substances into living cells
US5149655A (en) 1990-06-21 1992-09-22 Agracetus, Inc. Apparatus for genetic transformation
US5219746A (en) 1990-07-19 1993-06-15 Chris Brinegar Ice-mediated introduction of substances into biological material
DK0468735T3 (en) 1990-07-25 1995-07-17 Ici Plc Electrostatic spraying method
JP2977098B2 (en) 1990-08-31 1999-11-10 忠弘 大見 Charged material neutralization device
US5247842A (en) 1991-09-30 1993-09-28 Tsi Incorporated Electrospray apparatus for producing uniform submicrometer droplets
US5516670A (en) 1991-09-30 1996-05-14 Kuehnle; Adelheid R. Magnetophoretic particle delivery method and apparatus for the treatment of cells
GB9225098D0 (en) 1992-12-01 1993-01-20 Coffee Ronald A Charged droplet spray mixer
US6880554B1 (en) 1992-12-22 2005-04-19 Battelle Memorial Institute Dispensing device
US6105571A (en) 1992-12-22 2000-08-22 Electrosols, Ltd. Dispensing device
JPH06242273A (en) 1993-02-12 1994-09-02 Toshiba Corp Neutral particle injector
US5409162A (en) 1993-08-09 1995-04-25 Sickles; James E. Induction spray charging apparatus
US5534423A (en) 1993-10-08 1996-07-09 Regents Of The University Of Michigan Methods of increasing rates of infection by directing motion of vectors
US5506125A (en) 1993-12-22 1996-04-09 Agracetus, Inc. Gene delivery instrument with replaceable cartridges
ES2247248T3 (en) 1994-01-21 2006-03-01 Powderject Vaccines, Inc. GENES ADMINISTRATION INSTRUMENT MOVED BY COMPRESSED GAS.
US5457041A (en) 1994-03-25 1995-10-10 Science Applications International Corporation Needle array and method of introducing biological substances into living cells using the needle array
GB9406171D0 (en) 1994-03-29 1994-05-18 Electrosols Ltd Dispensing device
GB9406255D0 (en) 1994-03-29 1994-05-18 Electrosols Ltd Dispensing device
US5433865A (en) 1994-03-31 1995-07-18 Laurent; Edward L. Method for treating process waste streams by use of natural flocculants
GB9410658D0 (en) 1994-05-27 1994-07-13 Electrosols Ltd Dispensing device
US5475228A (en) 1994-11-28 1995-12-12 University Of Puerto Rico Unipolar blocking method and apparatus for monitoring electrically charged particles
JP2651478B2 (en) 1994-12-15 1997-09-10 春日電機株式会社 Static elimination method and device
US6126086A (en) 1995-01-10 2000-10-03 Georgia Tech Research Corp. Oscillating capillary nebulizer with electrospray
US5702754A (en) 1995-02-22 1997-12-30 Meadox Medicals, Inc. Method of providing a substrate with a hydrophilic coating and substrates, particularly medical devices, provided with such coatings
US5837313A (en) 1995-04-19 1998-11-17 Schneider (Usa) Inc Drug release stent coating process
US5525510A (en) 1995-06-02 1996-06-11 Agracetus, Inc. Coanda effect gene delivery instrument
US5714007A (en) 1995-06-06 1998-02-03 David Sarnoff Research Center, Inc. Apparatus for electrostatically depositing a medicament powder upon predefined regions of a substrate
US5609629A (en) 1995-06-07 1997-03-11 Med Institute, Inc. Coated implantable medical device
EP0862420A4 (en) 1995-10-13 1999-11-03 Penn State Res Found Synthesis of drug nanoparticles by spray drying
RU2196846C2 (en) 1995-11-13 2003-01-20 Дзе Юниверсити оф Коннектикут Nanostructural raw materials for thermic deposition
US5637357A (en) 1995-12-28 1997-06-10 Philips Electronics North America Corporation Rotary electrostatic dusting method
US5846595A (en) 1996-04-09 1998-12-08 Sarnoff Corporation Method of making pharmaceutical using electrostatic chuck
US6187214B1 (en) 1996-05-13 2001-02-13 Universidad De Seville Method and device for production of components for microfabrication
US6143037A (en) 1996-06-12 2000-11-07 The Regents Of The University Of Michigan Compositions and methods for coating medical devices
NL1003442C2 (en) 1996-06-27 1998-01-07 Univ Delft Tech A method of preparing a powder, a powder prepared by said method, an electrode and an apparatus for use in said method.
US6252129B1 (en) 1996-07-23 2001-06-26 Electrosols, Ltd. Dispensing device and method for forming material
US7193124B2 (en) 1997-07-22 2007-03-20 Battelle Memorial Institute Method for forming material
AU3628497A (en) 1996-07-23 1998-02-10 Electrosols Limited A dispensing device and method for forming material
US6933331B2 (en) 1998-05-22 2005-08-23 Nanoproducts Corporation Nanotechnology for drug delivery, contrast agents and biomedical implants
US5980972A (en) 1996-12-20 1999-11-09 Schneider (Usa) Inc Method of applying drug-release coatings
US5948483A (en) 1997-03-25 1999-09-07 The Board Of Trustees Of The University Of Illinois Method and apparatus for producing thin film and nanoparticle deposits
US6433154B1 (en) 1997-06-12 2002-08-13 Bristol-Myers Squibb Company Functional receptor/kinase chimera in yeast cells
US6207195B1 (en) 1997-06-13 2001-03-27 The Johns Hopkins University Therapeutic nanospheres
FR2766092B1 (en) 1997-07-16 1999-10-08 Centre Nat Rech Scient IMPLANTABLE DEVICE COATED WITH A POLYMER CAPABLE OF RELEASING BIOLOGICALLY ACTIVE SUBSTANCES
GB2327895B (en) 1997-08-08 2001-08-08 Electrosols Ltd A dispensing device
US5897911A (en) 1997-08-11 1999-04-27 Advanced Cardiovascular Systems, Inc. Polymer-coated stent structure
US6306166B1 (en) 1997-08-13 2001-10-23 Scimed Life Systems, Inc. Loading and release of water-insoluble drugs
US6143370A (en) 1997-08-27 2000-11-07 Northeastern University Process for producing polymer coatings with various porosities and surface areas
US5973904A (en) 1997-10-10 1999-10-26 Regents Of The University Of Minnesota Particle charging apparatus and method of charging particles
EP1037858A1 (en) 1997-12-17 2000-09-27 Universidad de Sevilla Device and method for creating spherical particles of uniform size
CA2314919A1 (en) 1997-12-17 1999-06-24 Alfonso Ganan Calvo Device and method for aeration of fluids
US5992244A (en) 1998-03-04 1999-11-30 Regents Of The University Of Minnesota Charged particle neutralizing apparatus and method of neutralizing charged particles
CA2320259C (en) 1998-04-27 2006-01-24 Surmodics, Inc. Bioactive agent release coating
US6242369B1 (en) * 1998-09-04 2001-06-05 Milliken & Company Method of improving washfastness of metallized fabric
GB2345010B (en) 1998-12-17 2002-12-31 Electrosols Ltd A delivery device
US6120847A (en) 1999-01-08 2000-09-19 Scimed Life Systems, Inc. Surface treatment method for stent coating
US6419692B1 (en) 1999-02-03 2002-07-16 Scimed Life Systems, Inc. Surface protection method for stents and balloon catheters for drug delivery
DE19911504B4 (en) * 1999-03-16 2006-02-23 Südzucker AG Mannheim/Ochsenfurt Process for the industrial oxidation of alcohols, aldehydes or polyhydroxy compounds
US6364903B2 (en) 1999-03-19 2002-04-02 Meadox Medicals, Inc. Polymer coated stent
US6368658B1 (en) 1999-04-19 2002-04-09 Scimed Life Systems, Inc. Coating medical devices using air suspension
JP4191330B2 (en) 1999-08-03 2008-12-03 浜松ホトニクス株式会社 Microdroplet forming method and microdroplet forming apparatus
US6419745B1 (en) 1999-11-16 2002-07-16 Advanced Cardiovascular Systems, Inc. Method and apparatus for polymer application to intracorporeal device
US6251136B1 (en) 1999-12-08 2001-06-26 Advanced Cardiovascular Systems, Inc. Method of layering a three-coated stent using pharmacological and polymeric agents
US6670607B2 (en) 2000-01-05 2003-12-30 The Research Foundation Of State University Of New York Conductive polymer coated nano-electrospray emitter
MXPA02008361A (en) 2000-02-28 2004-05-17 Genesegues Inc Nanocapsule encapsulation system and method.
US20020151004A1 (en) 2000-07-24 2002-10-17 Roger Craig Delivery vehicles and methods for using the same
DE10036907B4 (en) * 2000-07-28 2012-03-22 Xantec Bioanalytics Gmbh Process for the preparation of a coating on a gold vapor-deposited glass substrate, coating produced by this process and their use
WO2002064877A2 (en) 2001-01-30 2002-08-22 The Procter & Gamble Company Coating compositions for modifying surfaces
ES2180405B1 (en) 2001-01-31 2004-01-16 Univ Sevilla DEVICE AND PROCEDURE FOR PRODUCING MULTICOMPONENT COMPOSITE LIQUID JEANS AND MULTICOMPONENT AND / OR MULTI-PAPER MICRO AND NANOMETRIC SIZE CAPSULES.
EP1355537A4 (en) 2001-01-31 2010-04-07 Kraft Foods Global Brands Llc Production of capsules and particles for improvement of food products
US6669980B2 (en) 2001-09-18 2003-12-30 Scimed Life Systems, Inc. Method for spray-coating medical devices
US7776379B2 (en) 2001-09-19 2010-08-17 Medlogics Device Corporation Metallic structures incorporating bioactive materials and methods for creating the same
US20030064965A1 (en) 2001-10-02 2003-04-03 Jacob Richter Method of delivering drugs to a tissue using drug-coated medical devices
US7341211B2 (en) 2002-02-04 2008-03-11 Universidad De Sevilla Device for the production of capillary jets and micro-and nanometric particles
US20030161937A1 (en) 2002-02-25 2003-08-28 Leiby Mark W. Process for coating three-dimensional substrates with thin organic films and products
US6743463B2 (en) 2002-03-28 2004-06-01 Scimed Life Systems, Inc. Method for spray-coating a medical device having a tubular wall such as a stent
US20030232087A1 (en) * 2002-06-18 2003-12-18 Lawin Laurie R. Bioactive agent release coating with aromatic poly(meth)acrylates
US8211455B2 (en) 2002-06-19 2012-07-03 Boston Scientific Scimed, Inc. Implantable or insertable medical devices for controlled delivery of a therapeutic agent
US6982004B1 (en) * 2002-11-26 2006-01-03 Advanced Cardiovascular Systems, Inc. Electrostatic loading of drugs on implantable medical devices
US6918869B2 (en) 2002-12-02 2005-07-19 Scimed Life Systems System for administering a combination of therapies to a body lumen
US20050023368A1 (en) 2003-01-24 2005-02-03 S.C. Johnson & Son, Inc. Method of designing improved spray dispenser assemblies
WO2005017137A1 (en) 2003-03-12 2005-02-24 Affinium Pharmaceuticals, Inc. Novel purified polypeptides from hemophilus influenzae
US7261915B2 (en) 2003-04-09 2007-08-28 Boston Scientific Scimed, Inc. Electrohydrodynamic coating fluid delivery apparatus and method
US7524527B2 (en) 2003-05-19 2009-04-28 Boston Scientific Scimed, Inc. Electrostatic coating of a device
WO2005002643A2 (en) 2003-06-24 2005-01-13 Johns Hopkins University Method and products for delivering biological molecules to cells using multicomponent nanostructures
US8025637B2 (en) 2003-07-18 2011-09-27 Boston Scientific Scimed, Inc. Medical balloons and processes for preparing same
US20050055078A1 (en) 2003-09-04 2005-03-10 Medtronic Vascular, Inc. Stent with outer slough coating
US7906125B2 (en) 2003-09-18 2011-03-15 Boston Scientific Scimed, Inc. Solid or semi-solid therapeutic formulations
US8801692B2 (en) 2003-09-24 2014-08-12 Medtronic Vascular, Inc. Gradient coated stent and method of fabrication
US7309593B2 (en) 2003-10-01 2007-12-18 Surmodics, Inc. Attachment of molecules to surfaces
WO2005046746A2 (en) 2003-11-10 2005-05-26 Angiotech International Ag Medical implants and fibrosis-inducing agents
US7582430B2 (en) 2004-01-20 2009-09-01 United States Of America As Represented By The Secretary Of The Army Immunoliposome-nucleic acid amplification (ILNAA) assay
US7241344B2 (en) 2004-02-10 2007-07-10 Boston Scientific Scimed, Inc. Apparatus and method for electrostatic spray coating of medical devices
US6979473B2 (en) 2004-03-15 2005-12-27 Boston Scientific Scimed, Inc. Method for fine bore orifice spray coating of medical devices and pre-filming atomization
US7604830B2 (en) * 2004-06-24 2009-10-20 Cook Incorporated Method and apparatus for coating interior surfaces of medical devices
MX2007000308A (en) 2004-07-01 2007-04-10 Warner Lambert Co Preparation of pharmaceutical compositions containing nanoparticles.
US7356368B2 (en) 2004-07-21 2008-04-08 Boston Scientific Scimed, Inc. Light-activated anti-infective coatings and devices made thereof
US20060024810A1 (en) 2004-07-27 2006-02-02 Khadkikar Surendra B Method of atttaching nanotubes to bacteria and applications
US20060088566A1 (en) 2004-10-27 2006-04-27 Scimed Life Systems, Inc.,A Corporation Method of controlling drug release from a coated medical device through the use of nucleating agents
US20060099235A1 (en) 2004-11-11 2006-05-11 Medtronic Vascular, Inc. Medical devices and compositions useful for treating or inhibiting restenosis
CN100346001C (en) 2005-01-07 2007-10-31 中国科学院上海硅酸盐研究所 Method of preparing nano-titanium oxide coating layer having bioactivity
US20090104269A1 (en) 2005-02-11 2009-04-23 Brian Graham Nanoformulations
WO2006086654A2 (en) 2005-02-11 2006-08-17 Battelle Memorial Institute Nanoformulations
US8048350B2 (en) * 2005-10-31 2011-11-01 Scott Epstein Structural hydrogel polymer device
US7842312B2 (en) * 2005-12-29 2010-11-30 Cordis Corporation Polymeric compositions comprising therapeutic agents in crystalline phases, and methods of forming the same
WO2007089881A2 (en) 2006-01-31 2007-08-09 Regents Of The University Of Minnesota Electrospray coating of objects
EP1988941A2 (en) 2006-01-31 2008-11-12 Nanocopoeia, Inc. Nanoparticle coating of surfaces
EP2111305A2 (en) 2007-01-31 2009-10-28 Nanocopoeia, Inc. Nanoparticle coating of surfaces

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5873523A (en) * 1996-02-29 1999-02-23 Yale University Electrospray employing corona-assisted cone-jet mode
US20020007869A1 (en) * 2000-05-16 2002-01-24 Pui David Y.H. High mass throughput particle generation using multiple nozzle spraying
US20020065553A1 (en) * 2000-11-28 2002-05-30 Scimed Life System, Inc. Method for manufacturing a medical device having a coated portion by laser ablation
US20030143315A1 (en) * 2001-05-16 2003-07-31 Pui David Y H Coating medical devices
WO2005074913A2 (en) * 2004-01-30 2005-08-18 Angiotech International Ag Compositions and methods for treating contracture

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9108217B2 (en) 2006-01-31 2015-08-18 Nanocopoeia, Inc. Nanoparticle coating of surfaces
US9248217B2 (en) 2006-01-31 2016-02-02 Nanocopocia, LLC Nanoparticle coating of surfaces

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US20070278103A1 (en) 2007-12-06
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EP1988941A2 (en) 2008-11-12
WO2007089883A2 (en) 2007-08-09
CA2641117A1 (en) 2007-08-09
CA2641117C (en) 2018-01-02
EP2529761B1 (en) 2017-06-14

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