WO2007084391A3 - Thiazole compounds as protein kinase b ( pkb) inhibitors - Google Patents
Thiazole compounds as protein kinase b ( pkb) inhibitors Download PDFInfo
- Publication number
- WO2007084391A3 WO2007084391A3 PCT/US2007/000871 US2007000871W WO2007084391A3 WO 2007084391 A3 WO2007084391 A3 WO 2007084391A3 US 2007000871 W US2007000871 W US 2007000871W WO 2007084391 A3 WO2007084391 A3 WO 2007084391A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- thiazole compounds
- pkb
- protein kinase
- inhibitors
- compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Abstract
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BRPI0706621-0A BRPI0706621A2 (en) | 2006-01-18 | 2007-01-11 | compound, pharmaceutical composition, methods for treating a kinase-mediated disorder in a mammal and for treating a proliferation-related disorder in a mammal, and, use of the compound |
EA200801716A EA200801716A1 (en) | 2006-01-18 | 2007-01-11 | THIAZOLE COMPOUNDS AND THEIR APPLICATION |
EP07718125A EP1981884B1 (en) | 2006-01-18 | 2007-01-11 | Thiazole compounds as protein kinase b (pkb) inhibitors |
CA2636077A CA2636077C (en) | 2006-01-18 | 2007-01-11 | Thiazole compounds as protein kinase b (pkb) inhibitors |
ES07718125T ES2389062T3 (en) | 2006-01-18 | 2007-01-11 | Thiazole compounds as protein kinase B inhibitors (PKB) |
JP2008551297A JP5199885B2 (en) | 2006-01-18 | 2007-01-11 | Thiazole compounds as protein kinase B (PKB) inhibitors |
AU2007207743A AU2007207743B2 (en) | 2006-01-18 | 2007-01-11 | Thiazole compounds as protein kinase B (PKB) inhibitors |
IL192751A IL192751A0 (en) | 2006-01-18 | 2008-07-10 | Thiazole compounds as protein kinase b (pkb) inhibitors |
NO20083572A NO20083572L (en) | 2006-01-18 | 2008-08-18 | Thiazole compounds as protein kinase-B (PKB) inhibitors |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75954606P | 2006-01-18 | 2006-01-18 | |
US60/759,546 | 2006-01-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007084391A2 WO2007084391A2 (en) | 2007-07-26 |
WO2007084391A3 true WO2007084391A3 (en) | 2008-03-20 |
Family
ID=38180602
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2007/000871 WO2007084391A2 (en) | 2006-01-18 | 2007-01-11 | Thiazole compounds as protein kinase b ( pkb) inhibitors |
Country Status (21)
Country | Link |
---|---|
US (2) | US7514566B2 (en) |
EP (1) | EP1981884B1 (en) |
JP (1) | JP5199885B2 (en) |
KR (1) | KR20080091369A (en) |
CN (1) | CN101421265A (en) |
AR (1) | AR059064A1 (en) |
AU (1) | AU2007207743B2 (en) |
BR (1) | BRPI0706621A2 (en) |
CA (1) | CA2636077C (en) |
CR (1) | CR10211A (en) |
EA (1) | EA200801716A1 (en) |
ES (1) | ES2389062T3 (en) |
IL (1) | IL192751A0 (en) |
MY (1) | MY149143A (en) |
NO (1) | NO20083572L (en) |
PE (1) | PE20071114A1 (en) |
TW (1) | TW200738657A (en) |
UA (1) | UA91895C2 (en) |
UY (1) | UY30098A1 (en) |
WO (1) | WO2007084391A2 (en) |
ZA (1) | ZA200806386B (en) |
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Also Published As
Publication number | Publication date |
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JP5199885B2 (en) | 2013-05-15 |
CR10211A (en) | 2008-10-03 |
NO20083572L (en) | 2008-10-17 |
BRPI0706621A2 (en) | 2011-04-05 |
US20070173506A1 (en) | 2007-07-26 |
MY149143A (en) | 2013-07-15 |
UA91895C2 (en) | 2010-09-10 |
WO2007084391A2 (en) | 2007-07-26 |
UY30098A1 (en) | 2007-10-31 |
ES2389062T3 (en) | 2012-10-22 |
CA2636077A1 (en) | 2007-07-26 |
JP2009525960A (en) | 2009-07-16 |
US20090270445A1 (en) | 2009-10-29 |
EP1981884A2 (en) | 2008-10-22 |
CA2636077C (en) | 2012-01-03 |
ZA200806386B (en) | 2009-11-25 |
EA200801716A1 (en) | 2009-04-28 |
US7514566B2 (en) | 2009-04-07 |
AU2007207743B2 (en) | 2010-07-08 |
AR059064A1 (en) | 2008-03-12 |
US8084479B2 (en) | 2011-12-27 |
CN101421265A (en) | 2009-04-29 |
EP1981884B1 (en) | 2012-06-13 |
KR20080091369A (en) | 2008-10-10 |
AU2007207743A1 (en) | 2007-07-26 |
PE20071114A1 (en) | 2008-01-10 |
TW200738657A (en) | 2007-10-16 |
IL192751A0 (en) | 2009-02-11 |
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