WO2007081474A3 - System for dissociation and removal of proteinaceous tissue - Google Patents

System for dissociation and removal of proteinaceous tissue Download PDF

Info

Publication number
WO2007081474A3
WO2007081474A3 PCT/US2006/047185 US2006047185W WO2007081474A3 WO 2007081474 A3 WO2007081474 A3 WO 2007081474A3 US 2006047185 W US2006047185 W US 2006047185W WO 2007081474 A3 WO2007081474 A3 WO 2007081474A3
Authority
WO
WIPO (PCT)
Prior art keywords
tissue
dissociation
removal
proteinaceous tissue
energy field
Prior art date
Application number
PCT/US2006/047185
Other languages
French (fr)
Other versions
WO2007081474A2 (en
Inventor
Steven W Kovalcheck
Original Assignee
Alcon Inc
Steven W Kovalcheck
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE602006014206T priority Critical patent/DE602006014206D1/en
Application filed by Alcon Inc, Steven W Kovalcheck filed Critical Alcon Inc
Priority to KR1020087018975A priority patent/KR101296325B1/en
Priority to CA2632970A priority patent/CA2632970C/en
Priority to AT06849209T priority patent/ATE466537T1/en
Priority to CN2006800535452A priority patent/CN101389280B/en
Priority to MX2008008598A priority patent/MX2008008598A/en
Priority to EP06849209A priority patent/EP1968470B1/en
Priority to AU2006335194A priority patent/AU2006335194B2/en
Priority to JP2008549479A priority patent/JP5032500B2/en
Priority to BRPI0620895A priority patent/BRPI0620895B8/en
Publication of WO2007081474A2 publication Critical patent/WO2007081474A2/en
Publication of WO2007081474A3 publication Critical patent/WO2007081474A3/en
Priority to IL192344A priority patent/IL192344A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/00736—Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery

Abstract

An apparatus and method for the dissociation of soft proteinaceous tissue using pulsed rapid variable direction energy field flow fractionization is disclosed. The pulsed rapid disruptive energy field is created by the use of a probe which surrounds the soft proteinaceous tissue to be removed. Once the adhesive mechanism between tissue constituents has been compromised, fluidic techniques are used to remove the dissociated tissue.
PCT/US2006/047185 2006-01-03 2006-12-11 System for dissociation and removal of proteinaceous tissue WO2007081474A2 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
MX2008008598A MX2008008598A (en) 2006-01-03 2006-12-11 System for dissociation and removal of proteinaceous tissue.
KR1020087018975A KR101296325B1 (en) 2006-01-03 2006-12-11 System for dissociation and removal of proteinaceous tissue
CA2632970A CA2632970C (en) 2006-01-03 2006-12-11 System for dissociation and removal of proteinaceous tissue
AT06849209T ATE466537T1 (en) 2006-01-03 2006-12-11 SYSTEM FOR CLIVING AND REMOVAL OF PROTEINOUS TISSUE
CN2006800535452A CN101389280B (en) 2006-01-03 2006-12-11 System for dissociation and removal of proteinaceous tissue
DE602006014206T DE602006014206D1 (en) 2006-01-03 2006-12-11 SYSTEM FOR CUTTING AND REMOVING PROTEINOUS TISSUE
EP06849209A EP1968470B1 (en) 2006-01-03 2006-12-11 System for dissociation and removal of proteinaceous tissue
BRPI0620895A BRPI0620895B8 (en) 2006-01-03 2006-12-11 system for breaking connections that hold portions of soft tissue together
JP2008549479A JP5032500B2 (en) 2006-01-03 2006-12-11 System for dissociation and removal of proteinaceous tissue
AU2006335194A AU2006335194B2 (en) 2006-01-03 2006-12-11 System for dissociation and removal of proteinaceous tissue
IL192344A IL192344A (en) 2006-01-03 2008-06-19 System for breaking the bonds which hold proteins of soft tissue together

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75583906P 2006-01-03 2006-01-03
US60/755,839 2006-01-03

Publications (2)

Publication Number Publication Date
WO2007081474A2 WO2007081474A2 (en) 2007-07-19
WO2007081474A3 true WO2007081474A3 (en) 2007-09-07

Family

ID=38179730

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/047185 WO2007081474A2 (en) 2006-01-03 2006-12-11 System for dissociation and removal of proteinaceous tissue

Country Status (17)

Country Link
US (2) US7824870B2 (en)
EP (1) EP1968470B1 (en)
JP (1) JP5032500B2 (en)
KR (1) KR101296325B1 (en)
CN (1) CN101389280B (en)
AR (1) AR058905A1 (en)
AT (1) ATE466537T1 (en)
AU (1) AU2006335194B2 (en)
BR (1) BRPI0620895B8 (en)
CA (1) CA2632970C (en)
DE (1) DE602006014206D1 (en)
ES (1) ES2342790T3 (en)
IL (1) IL192344A (en)
MX (1) MX2008008598A (en)
RU (1) RU2419394C2 (en)
TW (1) TWI360410B (en)
WO (1) WO2007081474A2 (en)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8109981B2 (en) * 2005-01-25 2012-02-07 Valam Corporation Optical therapies and devices
JP4616683B2 (en) 2005-03-31 2011-01-19 富士通株式会社 Information processing apparatus and program
KR101471579B1 (en) * 2006-11-10 2014-12-11 라스 미카엘 라르센 Apparatus for non or minimally disruptive photomanipulation of an eye
WO2009026375A2 (en) * 2007-08-21 2009-02-26 Lehigh University Spermicidal and microbicidal compositions
US9402643B2 (en) 2008-01-15 2016-08-02 Novartis Ag Targeted illumination for surgical instrument
US8903488B2 (en) 2009-05-28 2014-12-02 Angiodynamics, Inc. System and method for synchronizing energy delivery to the cardiac rhythm
US9895189B2 (en) 2009-06-19 2018-02-20 Angiodynamics, Inc. Methods of sterilization and treating infection using irreversible electroporation
US8083737B2 (en) 2009-08-26 2011-12-27 Tyco Healthcare Group Lp Gas-enhanced surgical instrument with mechanism for cylinder puncture
US8835166B2 (en) * 2009-09-04 2014-09-16 The Regents Of The University Of California Extracellular matrix material created using non-thermal irreversible electroporation
US20110118728A1 (en) 2009-11-13 2011-05-19 Alcon Research, Ltd. Control of high-intensity pulsed electrical fields in surgical applications
US20110118729A1 (en) * 2009-11-13 2011-05-19 Alcon Research, Ltd High-intensity pulsed electric field vitrectomy apparatus with load detection
US20110118734A1 (en) * 2009-11-16 2011-05-19 Alcon Research, Ltd. Capsularhexis device using pulsed electric fields
US20110135626A1 (en) * 2009-12-08 2011-06-09 Alcon Research, Ltd. Localized Chemical Lysis of Ocular Tissue
US20110144638A1 (en) * 2009-12-14 2011-06-16 Alcon Research, Ltd. Localized Shockwave-Induced Tissue Disruption
US20110144562A1 (en) * 2009-12-14 2011-06-16 Alcon Research, Ltd. Localized Pharmacological Treatment of Ocular Tissue Using High-Intensity Pulsed Electrical Fields
WO2011081897A1 (en) * 2009-12-15 2011-07-07 Alcon Research, Ltd. High-intensity pulsed electric field vitrectomy apparatus
US8953651B2 (en) * 2010-02-24 2015-02-10 Alcon Lensx, Inc. High power femtosecond laser with repetition rate adjustable according to scanning speed
US20110288545A1 (en) * 2010-04-22 2011-11-24 Old Dominion University Research Foundation Method and Device for Ablation of Cancer and Resistance to New Cancer Growth
US8834462B2 (en) * 2010-06-01 2014-09-16 Covidien Lp System and method for sensing tissue characteristics
US20160074221A1 (en) * 2010-06-14 2016-03-17 Marie-Jose B. Tassignon Femtosecond laser apparatus for plasma induced vitreous ablation in the eye
US9149388B2 (en) 2010-09-29 2015-10-06 Alcon Research, Ltd. Attenuated RF power for automated capsulorhexis
US9700368B2 (en) 2010-10-13 2017-07-11 Angiodynamics, Inc. System and method for electrically ablating tissue of a patient
US20130041355A1 (en) * 2011-08-11 2013-02-14 Tammo Heeren Reducing Damage From A Dielectric Breakdown in Surgical Applications
US9078665B2 (en) 2011-09-28 2015-07-14 Angiodynamics, Inc. Multiple treatment zone ablation probe
CN104136046B (en) 2011-12-28 2017-06-09 雅培制药有限公司 The method and apparatus that biological carrying is reduced using sensing heating
NL2009424C2 (en) 2012-09-06 2014-03-10 D O R C Dutch Ophthalmic Res Ct International B V Irrigation/aspiration system, cartridge, pump unit, surgical machine, method for controlling.
US9522012B2 (en) 2012-09-13 2016-12-20 Shockwave Medical, Inc. Shockwave catheter system with energy control
US9333000B2 (en) 2012-09-13 2016-05-10 Shockwave Medical, Inc. Shockwave catheter system with energy control
US9730835B2 (en) 2012-12-19 2017-08-15 Novartis Ag Burst mode vitrectomy system
US9888956B2 (en) 2013-01-22 2018-02-13 Angiodynamics, Inc. Integrated pump and generator device and method of use
US9333024B2 (en) * 2013-03-07 2016-05-10 Arthrocare Corporation Electrosurgical systems and methods
US9549850B2 (en) * 2013-04-26 2017-01-24 Novartis Ag Partial venting system for occlusion surge mitigation
CA2914195C (en) 2013-06-03 2020-06-02 Nanoblate Corporation Methods and devices for stimulating an immune response using nanosecond pulsed electric fields
US20160023020A1 (en) * 2014-07-24 2016-01-28 Strathspey Crown Holdings, LLC System and Method for Inducing a Post-Operative Posterior Vitreous Detachment
US9974689B2 (en) 2014-11-06 2018-05-22 Novartis Ag Dual mode vitrectomy surgical system
AU2015355241B2 (en) 2014-12-01 2019-10-24 Pulse Biosciences, Inc. Nanoelectroablation control and vaccination
US10070988B2 (en) * 2014-12-18 2018-09-11 Novartis Ag Devices, systems, and methods for visualization of moving tissue with strobed illumination
CN105310821A (en) * 2015-05-15 2016-02-10 以诺康医疗科技（苏州）有限公司 Ultrasonic vitrectomy needle and device thereof
US10244931B2 (en) 2015-07-13 2019-04-02 Novartis Ag Illuminated ophthalmic infusion line and associated devices, systems, and methods
EP3141204B1 (en) * 2015-09-10 2021-07-28 Erbe Elektromedizin GmbH Ablation system for the large-scale surface coagulation of biological tissues
US11173008B2 (en) 2015-11-01 2021-11-16 Alcon Inc. Illuminated ophthalmic cannula
EP3181080A1 (en) * 2015-12-15 2017-06-21 Netvlieschirurg B.V. Microsurgical fine gripping and diathermy forceps and scissors
US10624785B2 (en) 2016-01-30 2020-04-21 Carl Zeiss Meditec Cataract Technology Inc. Devices and methods for ocular surgery
US9827066B2 (en) 2016-02-16 2017-11-28 Novartis Ag Methods and systems for pulsed illumination
US9956053B2 (en) 2016-03-04 2018-05-01 Novartis Ag Cannula with an integrated illumination feature
US20170319851A1 (en) * 2016-05-06 2017-11-09 Pulse Biosciences, Inc. Low-voltage impedance check pulse generator
JP7287888B2 (en) 2016-06-27 2023-06-06 ギャラリー，インコーポレイテッド A generator, a catheter with electrodes, and a method of treating a lung passageway
US10905492B2 (en) 2016-11-17 2021-02-02 Angiodynamics, Inc. Techniques for irreversible electroporation using a single-pole tine-style internal device communicating with an external surface electrode
CN110291843B (en) 2016-12-22 2022-06-28 雅培制药有限公司 Induction heating system for reducing biological carryover and control method thereof
AU2018261640B2 (en) 2017-05-04 2023-04-27 Carl Zeiss Meditec Cataract Technology Inc. Devices and methods for ocular surgery
US10996146B2 (en) 2017-06-01 2021-05-04 Becton, Dickinson And Company Devices for dissociating a biological tissue sample and methods of use thereof
EP3668430B1 (en) 2017-08-16 2024-02-14 Old Dominion University Research Foundation Targeted remote electrostimulation by interference of bipolar nanosecond pulses
US20190117196A1 (en) * 2017-10-19 2019-04-25 Canon Medical Systems Corporation Ultrasound diagnostic apparatus and ultrasound probe
US20220401261A1 (en) * 2017-12-07 2022-12-22 Harry Michael Lambert Ophthalmological surgery microsurgery instruments and methods of use in pars plana vitrectomy for increasing surgical precision and reducing vitreoretinal instrument insertions and removals and related trauma
KR102006907B1 (en) * 2018-03-12 2019-10-01 주식회사 씨오아이 Surgicalunit for ophthalmology
CN112702982B (en) 2018-06-05 2023-12-19 卡尔蔡司白内障医疗技术公司 Ophthalmic microsurgical tools, systems, and methods of use
EP3917468B1 (en) 2019-02-01 2023-11-15 Carl Zeiss Meditec Cataract Technology Inc. Ophthalmic cutting instruments having integrated aspiration pump
US20200309760A1 (en) * 2019-03-27 2020-10-01 Alcon Inc. Systems and methods for identifying material during an ophthalmic procedure using ac impedance measurement
WO2020236593A1 (en) 2019-05-17 2020-11-26 Carl Zeiss Meditec Cataract Technology Inc. Ophthalmic cutting instruments having integrated aspiration pump
AU2020288110A1 (en) 2019-06-07 2022-01-27 Carl Zeiss Meditec Cataract Technology Inc. Multi-stage trigger for ophthalmology cutting tool

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4597388A (en) * 1983-12-15 1986-07-01 Trutek Research, Inc. Apparatus for removing cataracts
DE19740530A1 (en) * 1997-09-15 1999-03-18 Kreco Kreiner Consulting Ges F Device for removing eye tissue, especially natural lens
US6135998A (en) * 1999-03-16 2000-10-24 Board Of Trustees Of The Leland Stanford Junior University Method and apparatus for pulsed plasma-mediated electrosurgery in liquid media
WO2001010319A1 (en) * 1999-08-04 2001-02-15 Eastern Virginia Medical School Of The Medical College Of Hampton Roads Method and apparatus for intracellular electro-manipulation

Family Cites Families (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4395258A (en) * 1980-11-03 1983-07-26 Cooper Medical Devices Linear intra-ocular suction device
US4849355A (en) * 1985-01-08 1989-07-18 Wong Tai Kin Method of transferring genes into cells
US6277112B1 (en) * 1996-07-16 2001-08-21 Arthrocare Corporation Methods for electrosurgical spine surgery
US5697882A (en) 1992-01-07 1997-12-16 Arthrocare Corporation System and method for electrosurgical cutting and ablation
US7429262B2 (en) 1992-01-07 2008-09-30 Arthrocare Corporation Apparatus and methods for electrosurgical ablation and resection of target tissue
US6749604B1 (en) 1993-05-10 2004-06-15 Arthrocare Corporation Electrosurgical instrument with axially-spaced electrodes
ES2149241T3 (en) 1993-11-10 2000-11-01 Xomed Inc BIPOLAR ELECTRO-SURGICAL INSTRUMENT AND MANUFACTURING METHOD.
US6632193B1 (en) 1995-06-07 2003-10-14 Arthrocare Corporation Systems and methods for electrosurgical tissue treatment
US7507341B2 (en) 1999-01-13 2009-03-24 Opencel Llc Method of and apparatus for converting biological materials into energy resources
US5914255A (en) 1996-03-06 1999-06-22 Grae; Joel B. Temperature shock method and apparatus
US5869326A (en) 1996-09-09 1999-02-09 Genetronics, Inc. Electroporation employing user-configured pulsing scheme
US6352535B1 (en) 1997-09-25 2002-03-05 Nanoptics, Inc. Method and a device for electro microsurgery in a physiological liquid environment
US6117660A (en) 1997-06-10 2000-09-12 Cytopulse Sciences, Inc. Method and apparatus for treating materials with electrical fields having varying orientations
US6855143B2 (en) 1997-06-13 2005-02-15 Arthrocare Corporation Electrosurgical systems and methods for recanalization of occluded body lumens
US6479785B1 (en) 1998-07-09 2002-11-12 Richard J. Fugo Device for plasma incision of mater with a specifically tuned radiofrequencty electromagnetic field generator
US6508816B2 (en) 1998-03-27 2003-01-21 John H. Shadduck Medical instrument working end creating very high pressure gradients
US5989212A (en) * 1998-06-04 1999-11-23 Alcon Laboratories, Inc. Pumping chamber for a liquefaction handpiece having a countersink electrode
US6787730B2 (en) 1998-07-09 2004-09-07 Damian Coccio Device for plasma incision of matter with a specifically tuned radiofrequency electromagnetic field generator
US7435247B2 (en) 1998-08-11 2008-10-14 Arthrocare Corporation Systems and methods for electrosurgical tissue treatment
US6192270B1 (en) 1998-08-14 2001-02-20 Genetronics, Inc. Apparatus and method for the delivery of drugs and genes into tissue
US6937890B2 (en) 1998-12-17 2005-08-30 University Of South Florida Nonpenetrating electroporation device
CA2364717A1 (en) 1999-03-24 2000-09-28 Instituut Voor Agrotechnologisch Onderzoek (Ato-Dlo) Method for treating products by high voltage pulses
US6678558B1 (en) 1999-03-25 2004-01-13 Genetronics, Inc. Method and apparatus for reducing electroporation-mediated muscle reaction and pain response
US7171264B1 (en) 1999-05-10 2007-01-30 Genetronics, Inc. Intradermal delivery of active agents by needle-free injection and electroporation
US6890332B2 (en) 1999-05-24 2005-05-10 Csaba Truckai Electrical discharge devices and techniques for medical procedures
US7053063B2 (en) 1999-07-21 2006-05-30 The Regents Of The University Of California Controlled electroporation and mass transfer across cell membranes in tissue
US7146210B2 (en) 2000-02-17 2006-12-05 Standen Ltd. Apparatus and method for optimizing tumor treatment efficiency by electric fields
US6679879B2 (en) 2000-08-16 2004-01-20 John H. Shadduck Electrical discharge catheter system for extracting emboli in endovascular interventions
US6795728B2 (en) 2001-08-17 2004-09-21 Minnesota Medical Physics, Llc Apparatus and method for reducing subcutaneous fat deposits by electroporation
EP1343800A4 (en) 2000-12-18 2005-06-29 Univ Princeton Fractionation of macro-molecules using asymmetric pulsed field electrophoresis
US7011790B2 (en) 2001-05-07 2006-03-14 Regents Of The University Of Minnesota Non-thermal disinfection of biological fluids using non-thermal plasma
US6994706B2 (en) 2001-08-13 2006-02-07 Minnesota Medical Physics, Llc Apparatus and method for treatment of benign prostatic hyperplasia
US6730075B2 (en) 2001-10-12 2004-05-04 The Board Of Trustees Of The Leland Stanford Junior University Surgical probe for use in liquid media
US6783647B2 (en) 2001-10-19 2004-08-31 Ut-Battelle, Llc Microfluidic systems and methods of transport and lysis of cells and analysis of cell lysate
US7058269B2 (en) * 2001-10-24 2006-06-06 Institut National D'optique Reconstructed glass for fiber optic applications
AU2002348417B9 (en) 2001-10-26 2010-02-04 Baylor College Of Medicine A composition and method to alter lean body mass and bone properties in a subject
AU2002348163A1 (en) 2001-11-02 2003-05-19 Intradigm Corporation Therapeutic methods for nucleic acid delivery vehicles
WO2003047684A2 (en) 2001-12-04 2003-06-12 University Of Southern California Method for intracellular modifications within living cells using pulsed electric fields
US20040219660A1 (en) 2001-12-14 2004-11-04 Dev Sukhendu B. Electroporation-mediated intravascular delivery
US8150520B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods for catheter-based renal denervation
US20070135875A1 (en) 2002-04-08 2007-06-14 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US8131371B2 (en) 2002-04-08 2012-03-06 Ardian, Inc. Methods and apparatus for monopolar renal neuromodulation
US8145317B2 (en) 2002-04-08 2012-03-27 Ardian, Inc. Methods for renal neuromodulation
US8145316B2 (en) 2002-04-08 2012-03-27 Ardian, Inc. Methods and apparatus for renal neuromodulation
US20070129761A1 (en) 2002-04-08 2007-06-07 Ardian, Inc. Methods for treating heart arrhythmia
WO2003089046A1 (en) 2002-04-16 2003-10-30 Cyto Pulse Sciences, Inc. Method of treating biological materials with translating electrical fields and electrode polarity reversal
US6780178B2 (en) 2002-05-03 2004-08-24 The Board Of Trustees Of The Leland Stanford Junior University Method and apparatus for plasma-mediated thermo-electrical ablation
US8043286B2 (en) 2002-05-03 2011-10-25 The Board Of Trustees Of The Leland Stanford Junior University Method and apparatus for plasma-mediated thermo-electrical ablation
US7141031B2 (en) 2002-05-24 2006-11-28 W. G. Holdings, Llc. Cervical collar with end-supported chin strap
FR2841796B1 (en) 2002-07-05 2005-03-04 Commissariat Energie Atomique TREATMENT OF EFFLUENTS ASSOCIATED WITH SOLID / LIQUID SEPARATION AND PULSED ELECTRIC FIELDS
US6746613B2 (en) 2002-11-04 2004-06-08 Steris Inc. Pulsed electric field system for treatment of a fluid medium
GB2395481B (en) 2002-11-19 2006-06-28 C Tech Innovation Ltd Control of biocatalysis reactions
US7316682B2 (en) 2002-12-17 2008-01-08 Aaron Medical Industries, Inc. Electrosurgical device to generate a plasma stream
US7059269B2 (en) 2003-02-13 2006-06-13 Steris, Inc. Pulsed electric field system for decontamination of biological agents on a dielectric sheet material
US7736361B2 (en) 2003-02-14 2010-06-15 The Board Of Trustees Of The Leland Stamford Junior University Electrosurgical system with uniformly enhanced electric field and minimal collateral damage
EP1603474B1 (en) 2003-02-14 2013-09-11 The Board Of Trustees Of The Leland Stanford Junior University Electrosurgical system with uniformly enhanced electric field and minimal collateral damage
JP4006696B2 (en) * 2003-02-21 2007-11-14 湘南デザイン株式会社 Lost wax precision casting mold manufacturing method
US7211083B2 (en) 2003-03-17 2007-05-01 Minnesota Medical Physics, Llc Apparatus and method for hair removal by electroporation
EP1648280A4 (en) 2003-06-18 2007-08-15 Univ Leland Stanford Junior Electro-adhesive tissue manipulator
US6960978B2 (en) * 2003-07-16 2005-11-01 Hewlett-Packard Development Company, L.P. Fuse structure
US20060269531A1 (en) 2003-07-18 2006-11-30 Eastern Virginia Medical School Apparatus for generating electrical pulses and methods of using the same
DE20312165U1 (en) 2003-08-01 2004-12-16 Belu Ag Enclosure with openable and closable side walls and roof areas as well as a roller door for this
JP5138229B2 (en) 2003-12-24 2013-02-06 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア Tissue ablation by irreversible electroporation
US7182762B2 (en) 2003-12-30 2007-02-27 Smith & Nephew, Inc. Electrosurgical device
US20050209548A1 (en) 2004-03-19 2005-09-22 Dev Sukhendu B Electroporation-mediated intravascular delivery
WO2005092433A1 (en) 2004-03-25 2005-10-06 University College Cork - National University Of Ireland, Cork Apparatus for prophylaxis or treatment of tissue
US20050238539A1 (en) 2004-04-01 2005-10-27 Gal Shafirstein Apparatus for automated fresh tissue sectioning
US7572998B2 (en) 2004-05-28 2009-08-11 Mohamed Abdel-Aleam H Method and device for creating a micro plasma jet
NL1026422C2 (en) 2004-06-15 2005-12-19 Univ Eindhoven Tech Device for creating a locally cold plasma at the location of an object.
AU2005289828A1 (en) 2004-09-24 2006-04-06 The Board Of Trustees Of The Leland Stanford Junior University Methods and devices for the non-thermal, electrically-induced closure of blood vessels
US8101169B2 (en) 2005-02-23 2012-01-24 The Board Of Trustees Of The Leland Stanford Junior University Ocular gene therapy using avalanche-mediated transfection
CA2612866A1 (en) 2005-05-11 2006-11-23 Corium International, Inc. Permeabilization of biological membranes
US20080039901A1 (en) 2005-06-03 2008-02-14 Kronberg James W Methods for modulating chondrocyte proliferation using pulsing electric fields
US20060293725A1 (en) 2005-06-24 2006-12-28 Boris Rubinsky Methods and systems for treating fatty tissue sites using electroporation
US20060293731A1 (en) 2005-06-24 2006-12-28 Boris Rubinsky Methods and systems for treating tumors using electroporation
US8114070B2 (en) 2005-06-24 2012-02-14 Angiodynamics, Inc. Methods and systems for treating BPH using electroporation
US20060293730A1 (en) 2005-06-24 2006-12-28 Boris Rubinsky Methods and systems for treating restenosis sites using electroporation
CA2547043C (en) 2005-08-05 2014-07-29 Mcgill University A plasma source and applications thereof
US20070265215A1 (en) 2006-05-11 2007-11-15 Iversen Patrick L Antisense restenosis composition and method
WO2008021321A2 (en) 2006-08-17 2008-02-21 Rjf Holdings Iv, Inc Method and apparatus for plasma incision of cardiovascular tissue
US7931811B2 (en) 2006-10-27 2011-04-26 Regents Of The University Of Minnesota Dielectric barrier reactor having concentrated electric field
GB2452103B (en) 2007-01-05 2011-08-31 Arthrocare Corp Electrosurgical system with suction control apparatus and system
US7655004B2 (en) 2007-02-15 2010-02-02 Ethicon Endo-Surgery, Inc. Electroporation ablation apparatus, system, and method
US8139339B2 (en) 2007-03-16 2012-03-20 Old Dominion University Research Foundation Modulation of neuromuscular functions with ultrashort electrical pulses
WO2008118393A1 (en) 2007-03-23 2008-10-02 University Of Southern California Compact subnanosecond high voltage pulse generation system for cell electro-manipulation
WO2008119749A1 (en) 2007-03-29 2008-10-09 Novozymes A/S Process for treating vegetable material with an enzyme
US20110118734A1 (en) * 2009-11-16 2011-05-19 Alcon Research, Ltd. Capsularhexis device using pulsed electric fields

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4597388A (en) * 1983-12-15 1986-07-01 Trutek Research, Inc. Apparatus for removing cataracts
DE19740530A1 (en) * 1997-09-15 1999-03-18 Kreco Kreiner Consulting Ges F Device for removing eye tissue, especially natural lens
US6135998A (en) * 1999-03-16 2000-10-24 Board Of Trustees Of The Leland Stanford Junior University Method and apparatus for pulsed plasma-mediated electrosurgery in liquid media
WO2001010319A1 (en) * 1999-08-04 2001-02-15 Eastern Virginia Medical School Of The Medical College Of Hampton Roads Method and apparatus for intracellular electro-manipulation

Also Published As

Publication number Publication date
EP1968470A2 (en) 2008-09-17
CN101389280A (en) 2009-03-18
MX2008008598A (en) 2008-09-26
TW200730157A (en) 2007-08-16
AU2006335194B2 (en) 2011-10-27
ES2342790T3 (en) 2010-07-14
DE602006014206D1 (en) 2010-06-17
RU2419394C2 (en) 2011-05-27
EP1968470B1 (en) 2010-05-05
JP5032500B2 (en) 2012-09-26
AU2006335194A1 (en) 2007-07-19
US7824870B2 (en) 2010-11-02
WO2007081474A2 (en) 2007-07-19
KR20080092400A (en) 2008-10-15
RU2008131943A (en) 2010-02-10
CN101389280B (en) 2011-02-16
US20100331911A1 (en) 2010-12-30
BRPI0620895B1 (en) 2018-05-22
AR058905A1 (en) 2008-03-05
BRPI0620895A2 (en) 2011-11-29
CA2632970A1 (en) 2007-07-19
JP2009522047A (en) 2009-06-11
BRPI0620895B8 (en) 2021-06-22
IL192344A (en) 2013-01-31
IL192344A0 (en) 2009-02-11
TWI360410B (en) 2012-03-21
CA2632970C (en) 2012-01-24
KR101296325B1 (en) 2013-08-14
ATE466537T1 (en) 2010-05-15
US20070156129A1 (en) 2007-07-05

Similar Documents

Publication Publication Date Title
WO2007081474A3 (en) System for dissociation and removal of proteinaceous tissue
WO2007087463A3 (en) Enhanced follicular extraction punch and method
WO2008076395A3 (en) Mechanically actuated diagnostic device
WO2007062652A3 (en) An apparatus and a method for cleaning a channel in a medical instrument
WO2008013818A3 (en) Method of denaturing and fragmenting dna or rna using ultrasound
WO2008142850A1 (en) Component separation device and method of component separation therewith
WO2009091925A3 (en) System and method for acoustic focusing hardware and implementations
EP2156178A4 (en) Methods and devices for enhanced analysis of field focused cells and particles
AU2003224930A1 (en) Apparatus and method for preshaped ultrasonic probe
WO2007147097A3 (en) Fluid treatment using plasma technology
EP2070079A4 (en) Method and apparatus for locating speech keyword and speech recognition system
TW200833310A (en) Method of operating a microsurgical instrument
PL363261A1 (en) A method and apparatus for isolation of ionic species by electrodialysis
ATE448562T1 (en) METHOD FOR DETECTING AN ARC DISCHARGE IN A PLASMA PROCESS AND ARC DISCHARGE DETECTION DEVICE
DE502005005490D1 (en) METHOD AND DEVICE FOR MONITORING AN SP
WO2008034833A3 (en) Apparatus for receiving biological specimens and method for laser dissection of biological specimens
IL176724A0 (en) Pulsed flow modulation method and device for gas chromatography
WO2011059504A3 (en) Method and apparatus for cleaning residue from an ion source component
WO2006066112A3 (en) Using parametric measurement units as a source of power for a device under test
GB2429777B (en) Method and apparatus for controlling the acoustic output of an airgun
WO2011017425A3 (en) Adapter system and method
WO2007070745A3 (en) Micro surgical cutting instruments
AU2003303542A8 (en) Method and apparatus for generating a membrane target for laser produced plasma
EP3892993A4 (en) Water removal method for gas concentration sampling, sampling method and device therefor
NO20084578L (en) Apparatus of method for sealing and insulating a pipeline

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 06849209

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 2632970

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2006849209

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2006335194

Country of ref document: AU

Ref document number: 12008501449

Country of ref document: PH

WWE Wipo information: entry into national phase

Ref document number: 5222/DELNP/2008

Country of ref document: IN

WWE Wipo information: entry into national phase

Ref document number: MX/a/2008/008598

Country of ref document: MX

WWE Wipo information: entry into national phase

Ref document number: 2008549479

Country of ref document: JP

NENP Non-entry into the national phase

Ref country code: DE

ENP Entry into the national phase

Ref document number: 2006335194

Country of ref document: AU

Date of ref document: 20061211

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 1020087018975

Country of ref document: KR

ENP Entry into the national phase

Ref document number: 2008131943

Country of ref document: RU

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 200680053545.2

Country of ref document: CN

ENP Entry into the national phase

Ref document number: PI0620895

Country of ref document: BR

Kind code of ref document: A2

Effective date: 20080703