WO2007078661A3 - Silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups - Google Patents

Silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups Download PDF

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Publication number
WO2007078661A3
WO2007078661A3 PCT/US2006/047193 US2006047193W WO2007078661A3 WO 2007078661 A3 WO2007078661 A3 WO 2007078661A3 US 2006047193 W US2006047193 W US 2006047193W WO 2007078661 A3 WO2007078661 A3 WO 2007078661A3
Authority
WO
WIPO (PCT)
Prior art keywords
capped
silicon
hydrophilic groups
containing monomers
cationic hydrophilic
Prior art date
Application number
PCT/US2006/047193
Other languages
French (fr)
Other versions
WO2007078661A2 (en
Inventor
Derek Schorzman
Joseph C Salamone
Jay Kunzler
Original Assignee
Bausch & Lomb
Derek Schorzman
Joseph C Salamone
Jay Kunzler
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bausch & Lomb, Derek Schorzman, Joseph C Salamone, Jay Kunzler filed Critical Bausch & Lomb
Priority to JP2008547297A priority Critical patent/JP5410761B2/en
Priority to CN2006800482972A priority patent/CN101341191B/en
Priority to ES06839294T priority patent/ES2389567T3/en
Priority to EP06839294A priority patent/EP1963403B1/en
Priority to AU2006333274A priority patent/AU2006333274A1/en
Priority to BRPI0620358A priority patent/BRPI0620358A2/en
Priority to CA002634241A priority patent/CA2634241A1/en
Publication of WO2007078661A2 publication Critical patent/WO2007078661A2/en
Publication of WO2007078661A3 publication Critical patent/WO2007078661A3/en
Priority to HK09101009.8A priority patent/HK1120279A1/en

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041—Lenses
    • G02B1/043—Contact lenses
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/04—Polysiloxanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
    • C08F290/06—Polymers provided for in subclass C08G
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
    • C08F290/06—Polymers provided for in subclass C08G
    • C08F290/061—Polyesters; Polycarbonates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
    • C08F290/06—Polymers provided for in subclass C08G
    • C08F290/068—Polysiloxanes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/04—Polysiloxanes
    • C08G77/22—Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen and oxygen
    • C08G77/26—Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen and oxygen nitrogen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/04—Polysiloxanes
    • C08G77/38—Polysiloxanes modified by chemical after-treatment
    • C08G77/382—Polysiloxanes modified by chemical after-treatment containing atoms other than carbon, hydrogen, oxygen or silicon
    • C08G77/388—Polysiloxanes modified by chemical after-treatment containing atoms other than carbon, hydrogen, oxygen or silicon containing nitrogen
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/10—Esters
    • C08F222/1006—Esters of polyhydric alcohols or polyhydric phenols
    • C08F222/102—Esters of polyhydric alcohols or polyhydric phenols of dialcohols, e.g. ethylene glycol di(meth)acrylate or 1,4-butanediol dimethacrylate

Abstract

The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. Such properties include the ability to extract the polymerized medical devices with water. This avoids the use of organic solvents as is typical in the art. The polymer compositions comprise polymerized silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups.
PCT/US2006/047193 2005-12-21 2006-12-11 Silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups WO2007078661A2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP2008547297A JP5410761B2 (en) 2005-12-21 2006-12-11 Silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups
CN2006800482972A CN101341191B (en) 2005-12-21 2006-12-11 Silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups
ES06839294T ES2389567T3 (en) 2005-12-21 2006-12-11 Monomers containing silicon terminally protected with polymerizable cationic hydrophilic groups
EP06839294A EP1963403B1 (en) 2005-12-21 2006-12-11 Silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups
AU2006333274A AU2006333274A1 (en) 2005-12-21 2006-12-11 Silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups
BRPI0620358A BRPI0620358A2 (en) 2005-12-21 2006-12-11 prepolymer, monomer mixture, device, method of fabricating a device, and silicon-containing monomer
CA002634241A CA2634241A1 (en) 2005-12-21 2006-12-11 Silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups
HK09101009.8A HK1120279A1 (en) 2005-12-21 2009-02-04 Silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US75266305P 2005-12-21 2005-12-21
US60/752,663 2005-12-21
US11/341,209 US7759408B2 (en) 2005-12-21 2006-01-27 Silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups
US11/341,209 2006-01-27

Publications (2)

Publication Number Publication Date
WO2007078661A2 WO2007078661A2 (en) 2007-07-12
WO2007078661A3 true WO2007078661A3 (en) 2007-08-30

Family

ID=38123747

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/047193 WO2007078661A2 (en) 2005-12-21 2006-12-11 Silicon-containing monomers end-capped with polymerizable cationic hydrophilic groups

Country Status (11)

Country Link
US (1) US7759408B2 (en)
EP (1) EP1963403B1 (en)
JP (1) JP5410761B2 (en)
KR (1) KR20080078685A (en)
CN (1) CN101341191B (en)
AU (1) AU2006333274A1 (en)
BR (1) BRPI0620358A2 (en)
CA (1) CA2634241A1 (en)
ES (1) ES2389567T3 (en)
HK (1) HK1120279A1 (en)
WO (1) WO2007078661A2 (en)

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