WO2007068885A3 - Active wound dressing materials - Google Patents

Active wound dressing materials Download PDF

Info

Publication number
WO2007068885A3
WO2007068885A3 PCT/GB2006/004511 GB2006004511W WO2007068885A3 WO 2007068885 A3 WO2007068885 A3 WO 2007068885A3 GB 2006004511 W GB2006004511 W GB 2006004511W WO 2007068885 A3 WO2007068885 A3 WO 2007068885A3
Authority
WO
WIPO (PCT)
Prior art keywords
wound dressing
dressing materials
sulfopropyl
wound
active wound
Prior art date
Application number
PCT/GB2006/004511
Other languages
French (fr)
Other versions
WO2007068885A2 (en
Inventor
Alicia Essler
Lorraine Nisbet
Original Assignee
Ethicon Inc
Alicia Essler
Lorraine Nisbet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethicon Inc, Alicia Essler, Lorraine Nisbet filed Critical Ethicon Inc
Publication of WO2007068885A2 publication Critical patent/WO2007068885A2/en
Publication of WO2007068885A3 publication Critical patent/WO2007068885A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/721—Dextrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/729—Agar; Agarose; Agaropectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/24—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/08—Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/16—Organic material
    • B01J39/18—Macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials For Medical Uses (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A wound dressing material comprising discrete particles of a strong cation exchange resin dispersed in a liquid-permeable matrix. Preferred resins are sulfopropyl dextrans and sulfopropyl agaroses. Also provided are wound dressings comprising such materials, and the use of such dressings for the treatment of wounds. The strong cation exchange materials selectively remove elastase from wound fluid.
PCT/GB2006/004511 2005-12-16 2006-12-04 Active wound dressing materials WO2007068885A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0525660.7 2005-12-16
GB0525660A GB2433205A (en) 2005-12-16 2005-12-16 Wound dressing comprising a strong cation exchange resin

Publications (2)

Publication Number Publication Date
WO2007068885A2 WO2007068885A2 (en) 2007-06-21
WO2007068885A3 true WO2007068885A3 (en) 2007-07-26

Family

ID=35736282

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2006/004511 WO2007068885A2 (en) 2005-12-16 2006-12-04 Active wound dressing materials

Country Status (2)

Country Link
GB (1) GB2433205A (en)
WO (1) WO2007068885A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8795730B2 (en) 2006-01-31 2014-08-05 David John Vachon Compositions and methods for promoting the healing of tissue of multicellular organisms
WO2007089902A2 (en) * 2006-01-31 2007-08-09 David Vachon Compositions and methods for promoting the healing of tissue of multicellular organisms
DE102006024748A1 (en) * 2006-05-26 2007-11-29 Paul Hartmann Ag Use of metalloprotease inhibitors such as polyacrylate for the preparation of an agent to treat chronic wound
US20110054375A1 (en) * 2007-11-27 2011-03-03 Hans Smola Dressing comprising polyacrylate particles and use thereof
US8454990B2 (en) 2008-08-01 2013-06-04 Milliken & Company Composite article suitable for use as a wound dressing

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB866723A (en) * 1956-10-11 1961-04-26 Permutit Co Ltd Improvements relating to ion-exchange membranes
WO2001066695A1 (en) * 2000-03-06 2001-09-13 United States Surgical Corporation Tissue compositions using cultured fibroblasts and keratinocytes and methods of use thereof
US20030175327A1 (en) * 2001-12-31 2003-09-18 Cochrum Kent C. Hemostatic compositions and methods for controlling bleeding
US20030206944A1 (en) * 2000-02-29 2003-11-06 Cohen Kelman I. Wound dressings with elastase-sequestering
GB2392913A (en) * 2002-09-11 2004-03-17 Johnson & Johnson Medical Ltd Complex of an anionic polysaccharide with silver
US20040142910A1 (en) * 2002-10-21 2004-07-22 Aegis Biosciences Llc Sulfonated styrene copolymers for medical uses

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1778143A4 (en) * 2004-07-12 2009-07-22 Aegis Biosciences Llc Sulfonated styrene polymers for medical articles

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB866723A (en) * 1956-10-11 1961-04-26 Permutit Co Ltd Improvements relating to ion-exchange membranes
US20030206944A1 (en) * 2000-02-29 2003-11-06 Cohen Kelman I. Wound dressings with elastase-sequestering
WO2001066695A1 (en) * 2000-03-06 2001-09-13 United States Surgical Corporation Tissue compositions using cultured fibroblasts and keratinocytes and methods of use thereof
US20030175327A1 (en) * 2001-12-31 2003-09-18 Cochrum Kent C. Hemostatic compositions and methods for controlling bleeding
GB2392913A (en) * 2002-09-11 2004-03-17 Johnson & Johnson Medical Ltd Complex of an anionic polysaccharide with silver
US20040142910A1 (en) * 2002-10-21 2004-07-22 Aegis Biosciences Llc Sulfonated styrene copolymers for medical uses

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
EDWARDS J V ET AL: "Modified cotton gauze dressings that selectively absorb neutrophil elastase activity in solution", WOUND REPAIR AND REGENERATION, MOSBY-YEAR BOOK, ST. LOUIS, MO, US, vol. 9, no. 1, January 2001 (2001-01-01), pages 50 - 58, XP002324103, ISSN: 1067-1927 *
VACHON DAVID J ET AL: "Novel sulfonated hydrogel composite with the ability to inhibit proteases and bacterial growth", JOURNAL OF BIOMEDICAL MATERIALS RESEARCH. PART A, WILEY, HOBOKEN, NY, US, vol. 76, no. 1, January 2006 (2006-01-01), pages 35 - 43, XP002423539, ISSN: 1549-3296 *

Also Published As

Publication number Publication date
GB2433205A (en) 2007-06-20
GB0525660D0 (en) 2006-01-25
WO2007068885A2 (en) 2007-06-21

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