WO2007048092A3 - Immunoassay for venom detection including noninvasive sample collection - Google Patents

Immunoassay for venom detection including noninvasive sample collection Download PDF

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Publication number
WO2007048092A3
WO2007048092A3 PCT/US2006/060039 US2006060039W WO2007048092A3 WO 2007048092 A3 WO2007048092 A3 WO 2007048092A3 US 2006060039 W US2006060039 W US 2006060039W WO 2007048092 A3 WO2007048092 A3 WO 2007048092A3
Authority
WO
WIPO (PCT)
Prior art keywords
venom
bite
sting
sample
immunoassay
Prior art date
Application number
PCT/US2006/060039
Other languages
French (fr)
Other versions
WO2007048092A2 (en
Inventor
William V Stoecker
Hernan Gomez
Jonathan A Green
David L Mcglasson
Original Assignee
Spidertech A Division Of Stoec
Univ Missouri
Us Air Force
Univ Michigan
William V Stoecker
Hernan Gomez
Jonathan A Green
David L Mcglasson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spidertech A Division Of Stoec, Univ Missouri, Us Air Force, Univ Michigan, William V Stoecker, Hernan Gomez, Jonathan A Green, David L Mcglasson filed Critical Spidertech A Division Of Stoec
Priority to BRPI0617500A priority Critical patent/BRPI0617500B8/en
Publication of WO2007048092A2 publication Critical patent/WO2007048092A2/en
Priority to IL190810A priority patent/IL190810A/en
Publication of WO2007048092A3 publication Critical patent/WO2007048092A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/42—Poisoning, e.g. from bites or stings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/97—Test strip or test slide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/81—Tube, bottle, or dipstick

Abstract

Methods and immunoassays for diagnosing a bite or sting of a venomous organism in a patient having symptoms consistent with such a bite or sting are provided. A sample of venom is collected from the area of the suspected bite or sting using a swab and then contacted with an antibody that specifically binds to an antigenic site on venom present in the sample. Binding is then detected. The invention is illustrated by examples showing diagnosis of brown recluse spider bite, distinguishing it from other diagnoses with which it is often confused. This extremely sensitive test can detect venom antigens down to about 20 picograms even after the sample has been shipped and stored for periods of up to three weeks during the summer.
PCT/US2006/060039 2005-10-17 2006-10-17 Immunoassay for venom detection including noninvasive sample collection WO2007048092A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
BRPI0617500A BRPI0617500B8 (en) 2005-10-17 2006-10-17 immunoassay kit for detection of recluse loxosceles venom
IL190810A IL190810A (en) 2005-10-17 2008-04-13 Immunoassay kit for venom detection

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72730005P 2005-10-17 2005-10-17
US60/727,300 2005-10-17

Publications (2)

Publication Number Publication Date
WO2007048092A2 WO2007048092A2 (en) 2007-04-26
WO2007048092A3 true WO2007048092A3 (en) 2008-07-10

Family

ID=37963402

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/060039 WO2007048092A2 (en) 2005-10-17 2006-10-17 Immunoassay for venom detection including noninvasive sample collection

Country Status (4)

Country Link
US (2) US7927828B2 (en)
BR (1) BRPI0617500B8 (en)
IL (1) IL190810A (en)
WO (1) WO2007048092A2 (en)

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US20120208222A1 (en) * 2011-02-10 2012-08-16 Andrew Mark Hecht Microchemical reactor

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Also Published As

Publication number Publication date
IL190810A (en) 2013-02-28
IL190810A0 (en) 2008-11-03
BRPI0617500B1 (en) 2018-02-14
BRPI0617500A2 (en) 2011-07-26
US8426154B2 (en) 2013-04-23
WO2007048092A2 (en) 2007-04-26
US7927828B2 (en) 2011-04-19
BRPI0617500B8 (en) 2021-07-27
US20100196938A1 (en) 2010-08-05
US20070141626A1 (en) 2007-06-21

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