WO2007038625A3 - Biodegradable nanocomposites with enhanced mechanical properties for soft tissue engineering. - Google Patents
Biodegradable nanocomposites with enhanced mechanical properties for soft tissue engineering. Download PDFInfo
- Publication number
- WO2007038625A3 WO2007038625A3 PCT/US2006/037723 US2006037723W WO2007038625A3 WO 2007038625 A3 WO2007038625 A3 WO 2007038625A3 US 2006037723 W US2006037723 W US 2006037723W WO 2007038625 A3 WO2007038625 A3 WO 2007038625A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- tissue engineering
- mechanical properties
- soft tissue
- enhanced mechanical
- poly
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
Abstract
The present invention is directed to a novel poly (diol citrates)-based nanocomposite materials created using completely biodegradable and biocompatible polymers that may be used in tissue engineering. More specifically, the specification describes methods and compositions for making and using nanocomposites comprised of citric acid copolymers and polymers including but not limited to poly(L-lactic acid) (PLLA) and poly(lactic-co-glycolic acid) (PLGA).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72168705P | 2005-09-28 | 2005-09-28 | |
US60/721,687 | 2005-09-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007038625A2 WO2007038625A2 (en) | 2007-04-05 |
WO2007038625A3 true WO2007038625A3 (en) | 2007-10-25 |
Family
ID=37900436
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/037723 WO2007038625A2 (en) | 2005-09-28 | 2006-09-28 | Biodegradable nanocomposites with enhanced mechanical properties for soft tissue engineering. |
Country Status (2)
Country | Link |
---|---|
US (2) | US20070071790A1 (en) |
WO (1) | WO2007038625A2 (en) |
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WO2007038246A2 (en) * | 2005-09-22 | 2007-04-05 | Medivas, Llc | Solid polymer delivery compositions and methods for use thereof |
WO2007035938A2 (en) | 2005-09-22 | 2007-03-29 | Medivas, Llc | BIS-(α-AMINO)-DIOL-DIESTER-CONTAINING POLY(ESTER AMIDE) AND POLY(ESTER URETHANE) COMPOSITIONS AND METHODS OF USE |
WO2007092583A2 (en) * | 2006-02-08 | 2007-08-16 | Northwestern University | Functionalizing implantable devices with a poly (diol-co-citrate) polymer |
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WO2007133616A2 (en) * | 2006-05-09 | 2007-11-22 | Medivas, Llc | Biodegradable water soluble polymers |
US7931651B2 (en) | 2006-11-17 | 2011-04-26 | Wake Lake University Health Sciences | External fixation assembly and method of use |
US8377016B2 (en) | 2007-01-10 | 2013-02-19 | Wake Forest University Health Sciences | Apparatus and method for wound treatment employing periodic sub-atmospheric pressure |
CN101679021B (en) | 2007-03-02 | 2014-04-30 | 伊利诺伊大学评议会 | Particulate drug delivery |
CA2685965A1 (en) | 2007-03-30 | 2008-10-09 | Medivas, Llc | Bioabsorbable elastomeric polymer networks, cross-linkers and methods of use |
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KR100963435B1 (en) * | 2008-06-19 | 2010-06-17 | 한국과학기술연구원 | Method of preparing biodegradable covered porous polymer microspheres for sustained-release drug delivery and tissue regeneration |
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CN110755447A (en) | 2013-01-04 | 2020-02-07 | 德克萨斯系统大学董事会 | Composition comprising citric acid and uses thereof |
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-
2006
- 2006-09-28 WO PCT/US2006/037723 patent/WO2007038625A2/en active Application Filing
- 2006-09-28 US US11/529,064 patent/US20070071790A1/en not_active Abandoned
-
2013
- 2013-11-18 US US14/083,071 patent/US9750845B2/en active Active
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US20040076681A1 (en) * | 2002-10-21 | 2004-04-22 | Dennis Donn M. | Nanoparticle delivery system |
US20050063939A1 (en) * | 2003-09-19 | 2005-03-24 | Northwestern University | Novel biodegradable elastomeric scaffold for tissue engineering and light scattering fingerprinting methods for testing the same |
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Also Published As
Publication number | Publication date |
---|---|
US9750845B2 (en) | 2017-09-05 |
US20140135407A1 (en) | 2014-05-15 |
US20070071790A1 (en) | 2007-03-29 |
WO2007038625A2 (en) | 2007-04-05 |
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