WO2007018622A3 - Vaginal treatment composition - Google Patents

Vaginal treatment composition Download PDF

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Publication number
WO2007018622A3
WO2007018622A3 PCT/US2006/011918 US2006011918W WO2007018622A3 WO 2007018622 A3 WO2007018622 A3 WO 2007018622A3 US 2006011918 W US2006011918 W US 2006011918W WO 2007018622 A3 WO2007018622 A3 WO 2007018622A3
Authority
WO
WIPO (PCT)
Prior art keywords
gel
less
vaginal
treatment composition
vaginal treatment
Prior art date
Application number
PCT/US2006/011918
Other languages
French (fr)
Other versions
WO2007018622A2 (en
Inventor
Stephanie M Martin
Lei Huang
Shu-Ping Yang
Yanbin Huang
Julie Villanueva
Sharon Linda Greene
Kelly Arehart
Curtis Sayre
Robert B Johnson
Original Assignee
Kimberly Clark Co
Stephanie M Martin
Lei Huang
Shu-Ping Yang
Yanbin Huang
Julie Villanueva
Sharon Linda Greene
Kelly Arehart
Curtis Sayre
Robert B Johnson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kimberly Clark Co, Stephanie M Martin, Lei Huang, Shu-Ping Yang, Yanbin Huang, Julie Villanueva, Sharon Linda Greene, Kelly Arehart, Curtis Sayre, Robert B Johnson filed Critical Kimberly Clark Co
Priority to EP06749023A priority Critical patent/EP1909841A2/en
Publication of WO2007018622A2 publication Critical patent/WO2007018622A2/en
Publication of WO2007018622A3 publication Critical patent/WO2007018622A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Abstract

A vaginal treatment composition that rapidly forms a gel when placed into contact with monovalent or polyvalent cations, such as sodium (Na+) and calcium (Ca2+) cations naturally found in vaginal mucosa, is provided. The gel may form in less than about 1 hour, in some embodiments less than about 1 minute, and in some embodiments, less than about 30 seconds. Among other things, such rapid gelation reduces the likelihood of leakage during use. In addition, because the gel may form intravaginally, it is more likely to retain its structure and shape over an extended period of time. In this manner, the gel may provide the prolonged release of a therapeutic agent that inhibits and/or treats vaginal infection. For instance, the gel may remain within the vagina for about 2 to about 48 hours to provide the desired effect.
PCT/US2006/011918 2005-07-29 2006-03-30 Vaginal treatment composition WO2007018622A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP06749023A EP1909841A2 (en) 2005-07-29 2006-03-30 Vaginal treatment composition

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/194,064 2005-07-29
US11/194,064 US7786176B2 (en) 2005-07-29 2005-07-29 Vaginal treatment composition containing xylitol

Publications (2)

Publication Number Publication Date
WO2007018622A2 WO2007018622A2 (en) 2007-02-15
WO2007018622A3 true WO2007018622A3 (en) 2007-05-18

Family

ID=37665735

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/011918 WO2007018622A2 (en) 2005-07-29 2006-03-30 Vaginal treatment composition

Country Status (3)

Country Link
US (1) US7786176B2 (en)
EP (1) EP1909841A2 (en)
WO (1) WO2007018622A2 (en)

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US7619008B2 (en) * 2004-11-12 2009-11-17 Kimberly-Clark Worldwide, Inc. Xylitol for treatment of vaginal infections
WO2008150526A1 (en) * 2007-06-04 2008-12-11 Shear/Kershman Laboratories, Inc. Tamper resistant lipid-based oral dosage form for opioid agonists
US8420700B1 (en) * 2008-06-04 2013-04-16 James M. Bausch Tamper resistant lipid-based oral dosage form for sympathomimetic amines
EP2130531A1 (en) * 2008-06-04 2009-12-09 Rolf Kullgren AB Vaginal suppository comprising lactic acid
DE102009008094A1 (en) 2009-02-09 2010-08-19 Barnikol-Keuten, Doris, Dr. In situ adhesive gel-forming preparations, in particular for topical application to moisturized skin / mucosa
DE202009017825U1 (en) 2009-02-14 2010-09-23 Luxexcel Holding Bv Device for directing light rays
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US9011909B2 (en) * 2010-09-03 2015-04-21 Wisconsin Pharmacal Company, Llc Prebiotic suppositories
BR112013027221A2 (en) * 2011-04-29 2016-12-27 Effik S A polyglycoside alkyl based vaginal composition
EP3355893A4 (en) 2015-09-29 2019-06-12 Kimberly-Clark Worldwide, Inc. Synergistic composition for maintenance of healthy balance of microflora
US9913871B2 (en) * 2016-04-15 2018-03-13 Fairhaven Health, Llc Compositions and methods for maintaining or enhancing homeostasis or function of female lower reproductive tract
BR112019013612B1 (en) 2017-01-31 2022-08-09 Kimberly-Clark Worldwide, Inc METHOD FOR INHIBITING BACTERIAL GROWTH IN A PRODUCT, ANTI-BACTERIAL COMPOSITION, AND, SWITCH.
WO2018203327A1 (en) 2017-04-30 2018-11-08 Resdevco Research And Development Co. Ltd. Composition containing phenethyl alcohol for treatment of candida infection
CN109157505A (en) * 2018-09-19 2019-01-08 广州纳微生物科技有限公司 Anti-bacteria wet keeping gel and preparation method thereof

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Also Published As

Publication number Publication date
WO2007018622A2 (en) 2007-02-15
US20070026074A1 (en) 2007-02-01
EP1909841A2 (en) 2008-04-16
US7786176B2 (en) 2010-08-31

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