WO2007002602A3 - Intervertebral disc prosthesis and associated methods - Google Patents

Intervertebral disc prosthesis and associated methods Download PDF

Info

Publication number
WO2007002602A3
WO2007002602A3 PCT/US2006/024838 US2006024838W WO2007002602A3 WO 2007002602 A3 WO2007002602 A3 WO 2007002602A3 US 2006024838 W US2006024838 W US 2006024838W WO 2007002602 A3 WO2007002602 A3 WO 2007002602A3
Authority
WO
WIPO (PCT)
Prior art keywords
plate
spring
leg
intervertebral disc
prosthesis
Prior art date
Application number
PCT/US2006/024838
Other languages
French (fr)
Other versions
WO2007002602A2 (en
Inventor
Missoum Moumene
Martin Masson
Original Assignee
Depuy Spine Inc
Missoum Moumene
Martin Masson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Depuy Spine Inc, Missoum Moumene, Martin Masson filed Critical Depuy Spine Inc
Priority to AU2006261793A priority Critical patent/AU2006261793A1/en
Priority to EP06774028A priority patent/EP1895948A2/en
Publication of WO2007002602A2 publication Critical patent/WO2007002602A2/en
Publication of WO2007002602A3 publication Critical patent/WO2007002602A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442Intervertebral or spinal discs, e.g. resilient
    • A61F2/4425Intervertebral or spinal discs, e.g. resilient made of articulated components
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006Properties of materials and coating materials
    • A61F2002/30092Properties of materials and coating materials using shape memory or superelastic materials, e.g. nitinol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/30199Three-dimensional shapes
    • A61F2002/30252Three-dimensional shapes quadric-shaped
    • A61F2002/30253Three-dimensional shapes quadric-shaped ellipsoidal or ovoid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30329Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2002/30331Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements made by longitudinally pushing a protrusion into a complementarily-shaped recess, e.g. held by friction fit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30329Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2002/30476Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements locked by an additional locking mechanism
    • A61F2002/305Snap connection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30329Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2002/30518Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements with possibility of relative movement between the prosthetic parts
    • A61F2002/30528Means for limiting said movement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30565Special structural features of bone or joint prostheses not otherwise provided for having spring elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30604Special structural features of bone or joint prostheses not otherwise provided for modular
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30621Features concerning the anatomical functioning or articulation of the prosthetic joint
    • A61F2002/30649Ball-and-socket joints
    • A61F2002/30662Ball-and-socket joints with rotation-limiting means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30841Sharp anchoring protrusions for impaction into the bone, e.g. sharp pins, spikes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442Intervertebral or spinal discs, e.g. resilient
    • A61F2/4425Intervertebral or spinal discs, e.g. resilient made of articulated components
    • A61F2002/443Intervertebral or spinal discs, e.g. resilient made of articulated components having two transversal endplates and at least one intermediate component
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0014Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/0033Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements made by longitudinally pushing a protrusion into a complementary-shaped recess, e.g. held by friction fit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0073Quadric-shaped
    • A61F2230/0076Quadric-shaped ellipsoidal or ovoid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00011Metals or alloys
    • A61F2310/00029Cobalt-based alloys, e.g. Co-Cr alloys or Vitallium

Abstract

An intervertebral disc prosthesis comprises a first plate designed for attachment to an upper vertebra and a second plate designed for attachment to a lower vertebra. A prosthesis core is positioned between the first plate and the second plate. At least one spring is connected between the first plate and the second plate. The spring comprises a U-shaped torsion bar including a first leg and a second leg. The first leg of the U-shaped torsion spring is attached to the first plate and the second leg is attached to the second plate. The spring provides a selected amount of resistance to movement of the first plate relative to the second plate. In one embodiment, the selected resistance is provided by the attachment locations of the spring to the plates. In another embodiment, the selected resistance is provided by a predetermined spring rate of the springs of the prosthesis.
PCT/US2006/024838 2005-06-27 2006-06-26 Intervertebral disc prosthesis and associated methods WO2007002602A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2006261793A AU2006261793A1 (en) 2005-06-27 2006-06-26 Intervertebral disc prosthesis and associated methods
EP06774028A EP1895948A2 (en) 2005-06-27 2006-06-26 Intervertebral disc prosthesis and associated methods

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/167,709 2005-06-27
US11/167,709 US20060293752A1 (en) 2005-06-27 2005-06-27 Intervertebral disc prosthesis and associated methods

Publications (2)

Publication Number Publication Date
WO2007002602A2 WO2007002602A2 (en) 2007-01-04
WO2007002602A3 true WO2007002602A3 (en) 2007-03-08

Family

ID=37568603

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/024838 WO2007002602A2 (en) 2005-06-27 2006-06-26 Intervertebral disc prosthesis and associated methods

Country Status (4)

Country Link
US (1) US20060293752A1 (en)
EP (1) EP1895948A2 (en)
AU (1) AU2006261793A1 (en)
WO (1) WO2007002602A2 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8841275B2 (en) 2010-11-30 2014-09-23 Gilead Pharmasset Llc 2′-spiro-nucleosides and derivatives thereof useful for treating hepatitis C virus and dengue virus infections
US8957046B2 (en) 2007-03-30 2015-02-17 Gilead Pharmasset Llc Nucleoside phosphoramidate prodrugs
US9045520B2 (en) 2008-12-23 2015-06-02 Gilead Pharmasset Llc Synthesis of purine nucleosides
US9393256B2 (en) 2011-09-16 2016-07-19 Gilead Pharmasset Llc Methods for treating HCV
US9549941B2 (en) 2011-11-29 2017-01-24 Gilead Pharmasset Llc Compositions and methods for treating hepatitis C virus

Families Citing this family (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7041309B2 (en) 2002-06-13 2006-05-09 Neuropro Technologies, Inc. Spinal fusion using an HMG-CoA reductase inhibitor
EP2329778A3 (en) 2003-01-31 2012-06-20 Spinalmotion, Inc. Spinal midline indicator
WO2004066884A1 (en) 2003-01-31 2004-08-12 Spinalmotion, Inc. Intervertebral prosthesis placement instrument
US7575599B2 (en) 2004-07-30 2009-08-18 Spinalmotion, Inc. Intervertebral prosthetic disc with metallic core
WO2004105638A2 (en) 2003-05-27 2004-12-09 Spinalmotion, Inc. Prosthetic disc for intervertebral insertion
US10052211B2 (en) 2003-05-27 2018-08-21 Simplify Medical Pty Ltd. Prosthetic disc for intervertebral insertion
US7585326B2 (en) 2004-08-06 2009-09-08 Spinalmotion, Inc. Methods and apparatus for intervertebral disc prosthesis insertion
US8597360B2 (en) 2004-11-03 2013-12-03 Neuropro Technologies, Inc. Bone fusion device
US8083797B2 (en) 2005-02-04 2011-12-27 Spinalmotion, Inc. Intervertebral prosthetic disc with shock absorption
US8486145B2 (en) * 2005-09-19 2013-07-16 Premia Spine Ltd. Flexure limiter for spinal prosthesis
US20070233244A1 (en) * 2006-03-28 2007-10-04 Depuy Spine, Inc. Artificial Disc Replacement Using Posterior Approach
US8282641B2 (en) * 2006-03-28 2012-10-09 Depuy Spine, Inc. Methods and instrumentation for disc replacement
US8137404B2 (en) * 2006-03-28 2012-03-20 Depuy Spine, Inc. Artificial disc replacement using posterior approach
US8734519B2 (en) 2006-04-12 2014-05-27 Spinalmotion, Inc. Posterior spinal device and method
US9526525B2 (en) 2006-08-22 2016-12-27 Neuropro Technologies, Inc. Percutaneous system for dynamic spinal stabilization
US8715350B2 (en) 2006-09-15 2014-05-06 Pioneer Surgical Technology, Inc. Systems and methods for securing an implant in intervertebral space
EP2066267A4 (en) * 2006-09-15 2013-03-06 Pioneer Surgical Technology Inc Systems and methods for sizing, inserting and securing an implant intervertebral space
US8377133B2 (en) 2006-09-15 2013-02-19 Pioneer Surgical Technology, Inc. Systems and methods for sizing, inserting and securing an implant in intervertebral space
US8029574B2 (en) 2006-11-07 2011-10-04 Biomedflex Llc Prosthetic knee joint
US9005307B2 (en) 2006-11-07 2015-04-14 Biomedflex, Llc Prosthetic ball-and-socket joint
US7905919B2 (en) 2006-11-07 2011-03-15 Biomedflex Llc Prosthetic joint
US8308812B2 (en) 2006-11-07 2012-11-13 Biomedflex, Llc Prosthetic joint assembly and joint member therefor
EP2081520B1 (en) 2006-11-07 2017-07-12 Biomedflex, LLC Medical implants
US8070823B2 (en) 2006-11-07 2011-12-06 Biomedflex Llc Prosthetic ball-and-socket joint
US8512413B2 (en) 2006-11-07 2013-08-20 Biomedflex, Llc Prosthetic knee joint
US20110166671A1 (en) 2006-11-07 2011-07-07 Kellar Franz W Prosthetic joint
US7914580B2 (en) 2006-11-07 2011-03-29 Biomedflex Llc Prosthetic ball-and-socket joint
US7892285B2 (en) * 2007-01-02 2011-02-22 Zimmer Spine, Inc. Universal joint total disc replacement
US8308801B2 (en) * 2007-02-12 2012-11-13 Brigham Young University Spinal implant
US8298287B2 (en) * 2007-06-26 2012-10-30 Depuy Spine, Inc. Intervertebral motion disc with helical shock absorber
ES2373980T3 (en) * 2007-07-26 2012-02-10 Biedermann Motech Gmbh INTERVERTEBRAL DISK PROSTHESIS.
US20090043391A1 (en) 2007-08-09 2009-02-12 Spinalmotion, Inc. Customized Intervertebral Prosthetic Disc with Shock Absorption
US8231676B2 (en) * 2007-09-17 2012-07-31 Pioneer Surgical Technology, Inc. Motion preserving artificial intervertebral disc device
US8758441B2 (en) 2007-10-22 2014-06-24 Spinalmotion, Inc. Vertebral body replacement and method for spanning a space formed upon removal of a vertebral body
DE102007058304A1 (en) * 2007-12-04 2009-06-10 Global Medical Consulting Gmbh Disc prosthesis
US20170216047A1 (en) * 2008-02-11 2017-08-03 Nexus TDR, Inc. Systems and Methods for Patient-Specific Total Disc Replacement
US8764833B2 (en) 2008-03-11 2014-07-01 Spinalmotion, Inc. Artificial intervertebral disc with lower height
US9034038B2 (en) 2008-04-11 2015-05-19 Spinalmotion, Inc. Motion limiting insert for an artificial intervertebral disc
KR20110009216A (en) 2008-05-05 2011-01-27 스피날모우션, 인코포레이티드 Polyaryletherketone artificial intervertebral disc
US9220603B2 (en) 2008-07-02 2015-12-29 Simplify Medical, Inc. Limited motion prosthetic intervertebral disc
EP2299944A4 (en) 2008-07-17 2013-07-31 Spinalmotion Inc Artificial intervertebral disc placement system
EP2299941A1 (en) 2008-07-18 2011-03-30 Spinalmotion Inc. Posterior prosthetic intervertebral disc
EP2376088B1 (en) 2008-12-23 2017-02-22 Gilead Pharmasset LLC 6-O-Substituted-2-amino-purine nucleoside phosphoramidates
SG172361A1 (en) 2008-12-23 2011-07-28 Pharmasset Inc Nucleoside analogs
JP2012514703A (en) * 2008-12-31 2012-06-28 エフ. ヒメネス、オマール Flexible joint configuration incorporating flexure members
US8628577B1 (en) 2009-03-19 2014-01-14 Ex Technology, Llc Stable device for intervertebral distraction and fusion
TWI598358B (en) 2009-05-20 2017-09-11 基利法瑪席特有限責任公司 Nucleoside phosphoramidates
US8618076B2 (en) 2009-05-20 2013-12-31 Gilead Pharmasset Llc Nucleoside phosphoramidates
US9358125B2 (en) 2009-07-22 2016-06-07 Spinex Tec, Llc Coaxial screw gear sleeve mechanism
US8636746B2 (en) 2009-12-31 2014-01-28 Spinex Tec, Llc Methods and apparatus for insertion of vertebral body distraction and fusion devices
PL2552930T3 (en) 2010-03-31 2016-02-29 Gilead Pharmasset Llc Crystalline (s)-isopropyl 2-(((s)-(((2r,3r,4r,5r)-5-(2,4-dioxo-3,4-dihydropyrimidin-1-(2h)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
UY33310A (en) 2010-03-31 2011-10-31 Pharmasset Inc ESTEREOSELECTIVE SYNTHESIS OF ASSETS CONTAINING PHOSPHORUS
US20110287403A1 (en) * 2010-05-21 2011-11-24 Ciccone Ii William Graft Tensioning Device
KR101052833B1 (en) * 2010-10-28 2011-07-29 박경우 A intervertebral cage having flexibility
US8998991B2 (en) * 2011-02-23 2015-04-07 Globus Medical, Inc. Six degree spine stabilization devices and methods
US9358123B2 (en) 2011-08-09 2016-06-07 Neuropro Spinal Jaxx, Inc. Bone fusion device, apparatus and method
US10420654B2 (en) 2011-08-09 2019-09-24 Neuropro Technologies, Inc. Bone fusion device, system and method
WO2013023096A1 (en) 2011-08-09 2013-02-14 Neuropro Technologies, Inc. Bone fusion device, system and method
US10159583B2 (en) 2012-04-13 2018-12-25 Neuropro Technologies, Inc. Bone fusion device
US9532883B2 (en) 2012-04-13 2017-01-03 Neuropro Technologies, Inc. Bone fusion device
US10258480B1 (en) 2012-10-20 2019-04-16 Carlos Andres Rodriguez Surgically implantable joint spacer
US9320611B2 (en) 2012-10-20 2016-04-26 Carlos Andres Rodriguez Surgically implantable joint spacer
MD4595B1 (en) 2013-01-31 2018-10-31 Gilead Pharmasset Llc. Combination formulation of two antiviral compounds
WO2014145766A1 (en) * 2013-03-15 2014-09-18 Paradigm Spine, Llc Modular, customizable spine stabilization system
WO2014151934A1 (en) 2013-03-15 2014-09-25 Neuropro Technologies, Inc. Bodiless bone fusion device, apparatus and method
US9198770B2 (en) * 2013-07-31 2015-12-01 Globus Medical, Inc. Artificial disc devices and related methods of use
NZ716840A (en) 2013-08-27 2017-06-30 Gilead Pharmasset Llc Combination formulation of two antiviral compounds
US9615935B2 (en) * 2014-01-30 2017-04-11 Titan Spine, Llc Thermally activated shape memory spring assemblies for implant expansion
US9486328B2 (en) 2014-04-01 2016-11-08 Ex Technology, Llc Expandable intervertebral cage
US8940049B1 (en) 2014-04-01 2015-01-27 Ex Technology, Llc Expandable intervertebral cage
RU2641854C2 (en) * 2015-09-10 2018-01-22 ФГАОУ ВО Севастопольский государственный университет Torsion intervertebral disk endoprosthesis
US10390959B2 (en) 2015-11-24 2019-08-27 Agada Medical Ltd. Intervertebral disc replacement
US11298931B2 (en) 2015-11-24 2022-04-12 Agada Medical Ltd. Intervertebral disc replacement
RU2653622C2 (en) * 2015-12-11 2018-05-11 Федеральное государственное автономное образовательное учреждение высшего образования "Севастопольский государственный университет" Six-step intervertebral disk endoprosthesis
RU2642722C2 (en) * 2016-01-12 2018-01-25 Федеральное государственное автономное образовательное учреждение высшего образования "Севастопольский государственный университет" Intervertebral disc endoprosthesis
RU2680917C2 (en) * 2016-05-26 2019-02-28 Федеральное государственное автономное образовательное учреждение высшего образования (ФГАОУ ВО) Севастопольский государственный университет Membrane-torsion intervertebral disc endoprosthesis
RU2653621C2 (en) * 2016-05-26 2018-05-11 Федеральное государственное автономное образовательное учреждение высшего образования (ФГАОУ ВО) Севастопольский государственный университет Interbody spinal endoprosthesis
US10213321B2 (en) 2017-01-18 2019-02-26 Neuropro Technologies, Inc. Bone fusion system, device and method including delivery apparatus
US10111760B2 (en) 2017-01-18 2018-10-30 Neuropro Technologies, Inc. Bone fusion system, device and method including a measuring mechanism
US10729560B2 (en) 2017-01-18 2020-08-04 Neuropro Technologies, Inc. Bone fusion system, device and method including an insertion instrument
US10973657B2 (en) 2017-01-18 2021-04-13 Neuropro Technologies, Inc. Bone fusion surgical system and method
JP2020533070A (en) 2017-09-08 2020-11-19 パイオニア サージカル テクノロジー インコーポレイテッド Intervertebral implants, instruments, and methods
USD907771S1 (en) 2017-10-09 2021-01-12 Pioneer Surgical Technology, Inc. Intervertebral implant
US10973658B2 (en) 2017-11-27 2021-04-13 Titan Spine, Inc. Rotating implant and associated instrumentation
US11135070B2 (en) 2018-02-14 2021-10-05 Titan Spine, Inc. Modular adjustable corpectomy cage
CN108836580A (en) * 2018-07-06 2018-11-20 北京爱康宜诚医疗器材有限公司 Artificial intervertebral disk frame body
US11129728B1 (en) 2018-10-03 2021-09-28 Guillermo Molina Surgically implantable joint spacer
CN109157312B (en) * 2018-10-23 2023-09-12 福州大学 Lumbar intervertebral disc prosthesis structure based on metal rubber and working method thereof
US11234835B2 (en) 2019-03-05 2022-02-01 Octagon Spine Llc Transversely expandable minimally invasive intervertebral cage
US11497622B2 (en) 2019-03-05 2022-11-15 Ex Technology, Llc Transversely expandable minimally invasive intervertebral cage and insertion and extraction device
US11642227B2 (en) * 2019-12-20 2023-05-09 Institute for Musculoskeletal Science and Education, Ltd. Dynamic disc assembly
US11684485B1 (en) 2020-02-04 2023-06-27 Guillermo Molina Surgically implantable joint spacer
MX2022011720A (en) * 2020-03-23 2023-01-04 Spinvention Llc Motion preserving spinal implant for total disc replacement.

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4759769A (en) * 1987-02-12 1988-07-26 Health & Research Services Inc. Artificial spinal disc
US5458642A (en) * 1994-01-18 1995-10-17 Beer; John C. Synthetic intervertebral disc
WO1996013209A1 (en) * 1994-10-31 1996-05-09 Haak Benjamin A Color coded medical instruments
WO1998022050A1 (en) * 1996-11-22 1998-05-28 Buttermann Glenn R Intervertebral prosthetic device
US6527804B1 (en) * 1998-12-11 2003-03-04 Dimso (Distribution Medicale Du Sud-Quest) Intervertebral disk prosthesis
US6770094B2 (en) * 2001-07-05 2004-08-03 Gerald Fehling Intervertebral disc prosthesis
WO2005011523A2 (en) * 2003-08-01 2005-02-10 Spinal Kinetics, Inc. Prosthetic intervertebral disc and methods for using same

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4208115A1 (en) * 1992-03-13 1993-09-16 Link Waldemar Gmbh Co DISC ENDOPROTHESIS
DE4208116C2 (en) * 1992-03-13 1995-08-03 Link Waldemar Gmbh Co Intervertebral disc prosthesis
US5423817A (en) * 1993-07-29 1995-06-13 Lin; Chih-I Intervertebral fusing device
US5514180A (en) * 1994-01-14 1996-05-07 Heggeness; Michael H. Prosthetic intervertebral devices
US6162252A (en) * 1997-12-12 2000-12-19 Depuy Acromed, Inc. Artificial spinal disc
US5989291A (en) * 1998-02-26 1999-11-23 Third Millennium Engineering, Llc Intervertebral spacer device
US7201776B2 (en) * 1999-10-08 2007-04-10 Ferree Bret A Artificial intervertebral disc replacements with endplates
US6579319B2 (en) * 2000-11-29 2003-06-17 Medicinelodge, Inc. Facet joint replacement
US6669730B2 (en) * 2001-02-15 2003-12-30 Spinecore, Inc. Intervertebral spacer device utilizing a spirally slotted belleville washer having radially extending grooves
US6673113B2 (en) * 2001-10-18 2004-01-06 Spinecore, Inc. Intervertebral spacer device having arch shaped spring elements
US6740117B2 (en) * 2001-02-15 2004-05-25 Spinecore, Inc. Intervertebral spacer device having a radially thinning slotted belleville spring
US6764515B2 (en) * 2001-02-15 2004-07-20 Spinecore, Inc. Intervertebral spacer device utilizing a spirally slotted belleville washer and a rotational mounting
US6887274B2 (en) * 2001-02-15 2005-05-03 Spinecore, Inc. Intervertebral spacer device utilizing a belleville washer having radially spaced concentric grooves
US6863688B2 (en) * 2001-02-15 2005-03-08 Spinecore, Inc. Intervertebral spacer device utilizing a spirally slotted belleville washer having radially spaced concentric grooves
US6726720B2 (en) * 2002-03-27 2004-04-27 Depuy Spine, Inc. Modular disc prosthesis
US6793678B2 (en) * 2002-06-27 2004-09-21 Depuy Acromed, Inc. Prosthetic intervertebral motion disc having dampening
US7156876B2 (en) * 2002-10-09 2007-01-02 Depuy Acromed, Inc. Intervertebral motion disc having articulation and shock absorption
WO2004105655A1 (en) * 2003-06-02 2004-12-09 Impliant Ltd. Spinal disc prosthesis
US7578847B2 (en) * 2005-03-03 2009-08-25 Cervical Xpand, Llc Posterior lumbar intervertebral stabilizer

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4759769A (en) * 1987-02-12 1988-07-26 Health & Research Services Inc. Artificial spinal disc
US5458642A (en) * 1994-01-18 1995-10-17 Beer; John C. Synthetic intervertebral disc
WO1996013209A1 (en) * 1994-10-31 1996-05-09 Haak Benjamin A Color coded medical instruments
WO1998022050A1 (en) * 1996-11-22 1998-05-28 Buttermann Glenn R Intervertebral prosthetic device
US6527804B1 (en) * 1998-12-11 2003-03-04 Dimso (Distribution Medicale Du Sud-Quest) Intervertebral disk prosthesis
US6770094B2 (en) * 2001-07-05 2004-08-03 Gerald Fehling Intervertebral disc prosthesis
WO2005011523A2 (en) * 2003-08-01 2005-02-10 Spinal Kinetics, Inc. Prosthetic intervertebral disc and methods for using same

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8957046B2 (en) 2007-03-30 2015-02-17 Gilead Pharmasset Llc Nucleoside phosphoramidate prodrugs
US9045520B2 (en) 2008-12-23 2015-06-02 Gilead Pharmasset Llc Synthesis of purine nucleosides
US8841275B2 (en) 2010-11-30 2014-09-23 Gilead Pharmasset Llc 2′-spiro-nucleosides and derivatives thereof useful for treating hepatitis C virus and dengue virus infections
US9393256B2 (en) 2011-09-16 2016-07-19 Gilead Pharmasset Llc Methods for treating HCV
US9549941B2 (en) 2011-11-29 2017-01-24 Gilead Pharmasset Llc Compositions and methods for treating hepatitis C virus

Also Published As

Publication number Publication date
WO2007002602A2 (en) 2007-01-04
US20060293752A1 (en) 2006-12-28
AU2006261793A1 (en) 2007-01-04
EP1895948A2 (en) 2008-03-12

Similar Documents

Publication Publication Date Title
WO2007002602A3 (en) Intervertebral disc prosthesis and associated methods
WO2007028096A3 (en) Prosthetic intervertebral discs
WO2006084194A3 (en) System and methods for monitoring during anterior surgery
WO2006072050A3 (en) System and methods for monitoring during anterior surgery
WO2006120505B1 (en) Intervertebral disc prosthesis
GB0522786D0 (en) Prosthetic spinal disc
WO2005013864A3 (en) Devices for replacing posterior elements of the spine
WO2005011523A3 (en) Prosthetic intervertebral disc and methods for using same
WO2006015088A3 (en) Spinal disc prosthesis and methods
WO2006023549A3 (en) Bar supports for a weight bench
PL380611A1 (en) Management of ophthalmologic disorders, including macular degeneration
WO2007000654A3 (en) Instrumentation and methods for inserting an intervertebral disc prosthesis
WO2006086494A3 (en) Intervertebral prosthetic disc
WO2007062283A3 (en) Posterior articular disc and method for implantation
IL178842A0 (en) Intervertebral disc prothesis
HK1110183A1 (en) Upholstery spring device
WO2006128036A3 (en) Spinal disc annulus augmentation
WO2008048743A3 (en) A foam spring mattress configured with variable firmness
GB2437190B (en) Safety valve with extension springs
AU2002335806A1 (en) Leaf spring rocker mechanism for a reclining chair
EP1621393A4 (en) Height adjusting device for car seat
WO2006071891A3 (en) Evaluating central nervous system
HK1119131A1 (en) Spring loaded spacer
WO2006076135A3 (en) Collapsible spring mechanisms for items of furniture
IL175836A0 (en) Foam material-based spring mattress

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2006261793

Country of ref document: AU

NENP Non-entry into the national phase

Ref country code: DE

ENP Entry into the national phase

Ref document number: 2006261793

Country of ref document: AU

Date of ref document: 20060626

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 2006774028

Country of ref document: EP