WO2006126201A2 - Suture loops for implantable device - Google Patents

Suture loops for implantable device Download PDF

Info

Publication number
WO2006126201A2
WO2006126201A2 PCT/IL2006/000616 IL2006000616W WO2006126201A2 WO 2006126201 A2 WO2006126201 A2 WO 2006126201A2 IL 2006000616 W IL2006000616 W IL 2006000616W WO 2006126201 A2 WO2006126201 A2 WO 2006126201A2
Authority
WO
WIPO (PCT)
Prior art keywords
header
securing
coupled
patient
securing element
Prior art date
Application number
PCT/IL2006/000616
Other languages
French (fr)
Other versions
WO2006126201A3 (en
Inventor
Ehud Cohen
Nir Betser
Avraham Biran
Tsachi Y. Y. Czackes Akselbrad
Original Assignee
Biocontrol Medical, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocontrol Medical, Ltd. filed Critical Biocontrol Medical, Ltd.
Publication of WO2006126201A2 publication Critical patent/WO2006126201A2/en
Publication of WO2006126201A3 publication Critical patent/WO2006126201A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/375—Constructional arrangements, e.g. casings
    • A61N1/37512—Pacemakers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/375—Constructional arrangements, e.g. casings
    • A61N1/37514—Brain implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/375—Constructional arrangements, e.g. casings
    • A61N1/37518—Anchoring of the implants, e.g. fixation

Definitions

  • the present invention relates generally to implantable medical devices, and specifically to methods and apparatus for implanting a can containing circuitry.
  • the control unit of an implantable electronic device such as a pacemaker or a defibrillator typically has two portions: a metal can, which includes the circuitry of the device, and a non-metallic header, which provides connection points for leads.
  • a hole is typically formed in the header to allow the control unit to be attached by suture to the implantation site.
  • an implantable can is . secured against rotation and/or translation at its implantation site, by using one or more securing elements that are coupled to the body of the can.
  • the securing elements may comprise suture loops, through which a' surgical needle and suture may be passed in order to facilitate the securing of the can to the implantation site.
  • the can is coupled to a header, which typically comprises one or more securing elements.
  • both the header and the can comprise securing elements, while for other applications only the header or only the can comprises the securing elements.
  • the can is implanted closer than the header to the head of the patient.
  • the can is typically secured at the implantation site using at least one securing element of the can. This typically reduces movement of the can during everyday motion of the patient, which movement may otherwise occur in the absence of such securing, if the can is closer than the header to the patient's head.
  • the can is coupled to a first header and a second header.
  • the second header includes one or more securing elements.
  • at least one of the headers includes one or more connection points for leads .
  • implantable apparatus including: a biocompatible can; a header, coupled to the can; at least one can securing element coupled to the can, for securing the can to tissue; and circuitry, disposed within the can.
  • the header includes a header securing element .
  • the at least one can securing element is shaped to define a loop through which a surgical needle and suture can be passed during implantation of the apparatus .
  • the at least one can securing element is an integral part of the can. In an embodiment, the at least one can securing element is connected to an outer surface of the can.
  • the at least one can securing element is welded to the outer surface of the can.
  • the loop is non-metallic.
  • implantable apparatus including: a biocompatible can; circuitry, disposed within the can; and a header coupled to the can and including at least two header securing elements, for securing the header to tissue.
  • the can includes at least one securing element .
  • implantable apparatus including: a biocompatible can; circuitry, disposed within the can; and two headers, disposed at opposite ends of the can.
  • at least one of the headers includes at least two header securing elements, for securing the at least one header to tissue.
  • the can includes at least one can securing element coupled to the can, for securing the can to tissue.
  • a method including: providing a device that includes a can and a header coupled to the can; and placing the device in a patient in an orientation in which the can is closer than the header to a head of the patient .
  • the method includes securing the can to an implantation site of the patient using a securing element of the can.
  • a method including: providing a device that includes a can and a header coupled to the can; placing the device in a patient; and securing, to tissue of the patient, at least one can securing element coupled to the can.
  • a method including: providing a device that includes a can and a header coupled to the can; placing the device in a patient; and securing, to tissue of the patient, at least two header securing elements coupled to the header.
  • a method including: providing a device that includes a can and two headers disposed at opposite ends of the can; and placing the device in a patient .
  • IA-C are several schematic views of an implantable can, in accordance with an embodiment of the present invention.
  • Figs. 2A-C are several schematic views of the can of Figs. IA-C coupled to a header, in accordance with an embodiment of the present invention.
  • Figs. 3A-C are several schematic views of the can of Figs. IA-C coupled to a first header and a second header, in accordance with an embodiment of the present invention.
  • FIGs. IA-C are several schematic views of an implantable can 10, in accordance with an embodiment of the present invention.
  • can 10 holds circuitry (not shown) for an implantable device, such as a stimulator or sensor.
  • the circuitry may comprise a control unit and/or circuitry for operating a cardiac pacemaker, a defibrillator, an ICD, or a pelvic floor muscle stimulator, or other circuitry for applying signals to and/or sensing activity of tissue (e.g., heart, pancreas, liver, gastrointestinal tract, brain, or nerve tissue) .
  • Can 10 is typically secured against rotation and/or translation at its implantation site, by using one or more securing elements that are coupled to the body of can 10
  • the securing elements may comprise suture loops 12, through which a surgical needle and suture may be passed in order to facilitate the securing of the can to the implantation site.
  • Loops 12 may be circular (configuration not shown) or not circular.
  • suture loops 12 may be laser welded or otherwise welded to can 10 (as shown) , or they may be attached to the can using other techniques known in the art.
  • Suture loops 12 typically comprise a biocompatible metal, such as titanium or stainless steel, or a biocompatible non-metal, such as silicone, polyurethane, or epoxy.
  • the securing elements are an integral component of can 10. For example, if the can is formed by casting, then the securing elements may be formed during the same casting process. In this case, the securing elements may be outside of the overall body of the can (as shown in Figs. IA-C), or they may be formed as holes passing through the body of the can (configuration not shown) .
  • can 10 may be coupled to a single securing element, or, alternatively, to three, four, or more securing elements.
  • the number of securing elements is set in accordance with characteristics of the implantation site and the size of the can.
  • the locations of the securing elements shown in Figs. IA-C is by way of illustration and not limitation; in other applications, the securing elements are disposed at different locations on the can.
  • FIGs. 2A-C are several schematic views of can 10 coupled to a header 14, in accordance with an embodiment of the present invention.
  • Header 14 typically, but not necessarily, comprises a plastic, epoxy, or other suitable biocompatible material known in the art.
  • the header typically comprises one or more securing elements.
  • the securing element is formed by shaping header 14 to define a hole 16 passing therethrough.
  • header 14 comprises two, three, or more securing elements (e.g., holes) which permit securing of the header to the implantation site.
  • header 14 comprises one or more connection points 18 for leads (leads not shown) .
  • both header 14 and can 10 comprise securing elements (configuration shown in Figs. 2A- C) , while for other applications only the header or only the can comprises the securing elements.
  • can 10 is implanted closer than header 14 to the head of the patient.
  • the can is typically secured at the implantation site using at least one securing element of the can. This typically reduces movement of the can during everyday motion of the patient, which movement may otherwise occur in the absence of such securing, if the can is closer than the header to the patient's head.
  • leads (not shown) leaving the header are typically (a) further from the incision site, and/or (b) closer to a stimulation/sensing site.
  • Figs. 3A-C are several schematic views of can 10 coupled to a first header 14A (typically as described hereinabove with reference to header 14 in Figs. 2A-C), and also coupled to a second header 14B, in accordance with an embodiment of the present invention.
  • the second header typically but not necessarily comprises the same material as the first header.
  • the first and second headers may both comprise a transparent material.
  • one or both of the headers is not transparent.
  • second header 14B comprises one or more securing elements (e.g., holes 16, as shown) .
  • at least one of the headers, e.g., header 14A includes one or more connection points 18 for leads.
  • second header 14B does not comprise any securing elements or connection points 18.
  • can 10 comprises one or more securing elements, such as loops 12, while for other applications, the can does not comprise any securing elements.

Abstract

Implantable apparatus is provided, including a biocompatible can (10); a header (14), coupled to the can (10); at least one can securing element (12) coupled to the can (10), for securing the can (10) to tissue; and circuitry, disposed within the can (10). Other embodiments are also described.

Description

SUTURE LOOPS FOR IMPLANTABLE DEVICE
CROSS-REFERENCES TO RELATED APPLICATIONS
The present application claims the benefit of US Provisional Patent Application 60/685,234, filed May 26, 2005, which is assigned to the assignee of the present application and is incorporated herein by reference.
FIELD OF THE INVENTION
The present invention relates generally to implantable medical devices, and specifically to methods and apparatus for implanting a can containing circuitry.
BACKGROUND OF THE INVENTION
The control unit of an implantable electronic device such as a pacemaker or a defibrillator typically has two portions: a metal can, which includes the circuitry of the device, and a non-metallic header, which provides connection points for leads. A hole is typically formed in the header to allow the control unit to be attached by suture to the implantation site.
SUMMARY OF THE INVENTION In some embodiments of the present invention, an implantable can is . secured against rotation and/or translation at its implantation site, by using one or more securing elements that are coupled to the body of the can. For example, the securing elements may comprise suture loops, through which a' surgical needle and suture may be passed in order to facilitate the securing of the can to the implantation site. In some embodiments of the present invention, the can is coupled to a header, which typically comprises one or more securing elements. For some applications, both the header and the can comprise securing elements, while for other applications only the header or only the can comprises the securing elements.
In some embodiments of the present invention, the can is implanted closer than the header to the head of the patient. In these embodiments, the can is typically secured at the implantation site using at least one securing element of the can. This typically reduces movement of the can during everyday motion of the patient, which movement may otherwise occur in the absence of such securing, if the can is closer than the header to the patient's head. In some embodiments of the present invention, the can is coupled to a first header and a second header. For some applications, the second header includes one or more securing elements. Alternatively or additionally, at least one of the headers includes one or more connection points for leads .
There is therefore provided, in accordance with an embodiment of the present ' invention, implantable apparatus, including: a biocompatible can; a header, coupled to the can; at least one can securing element coupled to the can, for securing the can to tissue; and circuitry, disposed within the can.
In an embodiment, the header includes a header securing element . In an embodiment, the at least one can securing element is shaped to define a loop through which a surgical needle and suture can be passed during implantation of the apparatus .
In an embodiment, the at least one can securing element is an integral part of the can. In an embodiment, the at least one can securing element is connected to an outer surface of the can.
In an embodiment, the at least one can securing element is welded to the outer surface of the can.
In an embodiment, the loop is non-metallic. There is further provided, in accordance with an embodiment of the present invention, implantable apparatus, including: a biocompatible can; circuitry, disposed within the can; and a header coupled to the can and including at least two header securing elements, for securing the header to tissue.
In an embodiment, the can includes at least one securing element .
There is yet further provided, in accordance with an embodiment of the present invention, implantable apparatus, including: a biocompatible can; circuitry, disposed within the can; and two headers, disposed at opposite ends of the can. For some applications, at least one of the headers includes at least two header securing elements, for securing the at least one header to tissue. Alternatively or additionally, the can includes at least one can securing element coupled to the can, for securing the can to tissue. There is still further provided, in accordance with an embodiment of the present invention, a method including: providing a device that includes a can and a header coupled to the can; and placing the device in a patient in an orientation in which the can is closer than the header to a head of the patient .
In an embodiment, the method includes securing the can to an implantation site of the patient using a securing element of the can.
There is additionally provided, in accordance with an embodiment of the present invention, a method including: providing a device that includes a can and a header coupled to the can; placing the device in a patient; and securing, to tissue of the patient, at least one can securing element coupled to the can.
There is yet additionally provided, in accordance with an embodiment of the present invention, a method including: providing a device that includes a can and a header coupled to the can; placing the device in a patient; and securing, to tissue of the patient, at least two header securing elements coupled to the header.
There is also provided, in accordance with an embodiment of the present invention, a method including: providing a device that includes a can and two headers disposed at opposite ends of the can; and placing the device in a patient . The present invention will be more fully understood from the following detailed description of embodiments thereof, taken together with the drawings, in which:
BRIEF DESCRIPTION OF THE DRAWINGS Figs . IA-C are several schematic views of an implantable can, in accordance with an embodiment of the present invention;
Figs. 2A-C are several schematic views of the can of Figs. IA-C coupled to a header, in accordance with an embodiment of the present invention; and
Figs. 3A-C are several schematic views of the can of Figs. IA-C coupled to a first header and a second header, in accordance with an embodiment of the present invention.
DETAILED DESCRIPTION OF EMBODIMENTS Figs. IA-C are several schematic views of an implantable can 10, in accordance with an embodiment of the present invention. Typically, but not necessarily, can 10 holds circuitry (not shown) for an implantable device, such as a stimulator or sensor. For example, the circuitry may comprise a control unit and/or circuitry for operating a cardiac pacemaker, a defibrillator, an ICD, or a pelvic floor muscle stimulator, or other circuitry for applying signals to and/or sensing activity of tissue (e.g., heart, pancreas, liver, gastrointestinal tract, brain, or nerve tissue) . Can 10 is typically secured against rotation and/or translation at its implantation site, by using one or more securing elements that are coupled to the body of can 10
(i.e., connected to or integral with the body of can 10) .
For example, the securing elements may comprise suture loops 12, through which a surgical needle and suture may be passed in order to facilitate the securing of the can to the implantation site. Loops 12 may be circular (configuration not shown) or not circular. By way of illustration and not limitation, suture loops 12 may be laser welded or otherwise welded to can 10 (as shown) , or they may be attached to the can using other techniques known in the art. Suture loops 12 typically comprise a biocompatible metal, such as titanium or stainless steel, or a biocompatible non-metal, such as silicone, polyurethane, or epoxy. Alternatively, the securing elements are an integral component of can 10. For example, if the can is formed by casting, then the securing elements may be formed during the same casting process. In this case, the securing elements may be outside of the overall body of the can (as shown in Figs. IA-C), or they may be formed as holes passing through the body of the can (configuration not shown) .
Although two securing elements are shown in Fig. IA, it is to be understood that can 10 may be coupled to a single securing element, or, alternatively, to three, four, or more securing elements. Typically, the number of securing elements is set in accordance with characteristics of the implantation site and the size of the can. Similarly, the locations of the securing elements shown in Figs. IA-C is by way of illustration and not limitation; in other applications, the securing elements are disposed at different locations on the can.
It is noted that although some embodiments of the present invention are described herein with respect to attaching the securing elements to the implantation site using suture, other suitable surgical attachment mechanisms may be used, as appropriate. Figs. 2A-C are several schematic views of can 10 coupled to a header 14, in accordance with an embodiment of the present invention. Header 14 typically, but not necessarily, comprises a plastic, epoxy, or other suitable biocompatible material known in the art. The header typically comprises one or more securing elements. In the embodiment shown in Figs. 2A-C, the securing element is formed by shaping header 14 to define a hole 16 passing therethrough. For some applications, header 14 comprises two, three, or more securing elements (e.g., holes) which permit securing of the header to the implantation site. For some applications, header 14 comprises one or more connection points 18 for leads (leads not shown) .
For some applications, both header 14 and can 10 comprise securing elements (configuration shown in Figs. 2A- C) , while for other applications only the header or only the can comprises the securing elements.
Reference is again made to Figs. IA-C and 2A-C. In an embodiment, can 10 is implanted closer than header 14 to the head of the patient. In this embodiment, the can is typically secured at the implantation site using at least one securing element of the can. This typically reduces movement of the can during everyday motion of the patient, which movement may otherwise occur in the absence of such securing, if the can is closer than the header to the patient's head. In this embodiment, leads (not shown) leaving the header are typically (a) further from the incision site, and/or (b) closer to a stimulation/sensing site.
Figs. 3A-C are several schematic views of can 10 coupled to a first header 14A (typically as described hereinabove with reference to header 14 in Figs. 2A-C), and also coupled to a second header 14B, in accordance with an embodiment of the present invention. The second header typically but not necessarily comprises the same material as the first header. For example, the first and second headers may both comprise a transparent material. Alternatively, one or both of the headers is not transparent. For some applications, second header 14B comprises one or more securing elements (e.g., holes 16, as shown) . Alternatively or additionally, at least one of the headers, e.g., header 14A, includes one or more connection points 18 for leads. In an embodiment, second header 14B does not comprise any securing elements or connection points 18. For some applications, can 10 comprises one or more securing elements, such as loops 12, while for other applications, the can does not comprise any securing elements. It will be appreciated by persons skilled in the art that the present invention is not limited to what has been particularly shown and described hereinabove. Rather, the scope of the present invention includes both combinations and subcombinations of the various features described hereinabove, as well as variations and modifications thereof that are not in the prior art, which would occur to persons skilled in the art upon reading the foregoing description.

Claims

1. Implantable apparatus, comprising: a biocompatible can; a header, coupled to the can; at least one can securing element coupled to the can, for securing the can to tissue; and circuitry, disposed within the can.
2. The apparatus according to claim 1, wherein the header comprises a header securing element.
3. The apparatus according to any one of claims 1-2, wherein the at least one can securing element is shaped to define a loop through which a surgical needle and suture can be passed during implantation of the apparatus.
4. The apparatus according to claim 3, wherein the at least one can securing element is an integral part of the can.
5. The apparatus according to claim 3, wherein the at least one can securing element is connected to an outer surface of the can.
6. The apparatus according to claim 5, wherein the at least one can securing element is welded to the outer surface of the can.
7. The apparatus according to claim 5, wherein the loop is non-metallic.
8. Implantable apparatus, comprising: a biocompatible can; circuitry, disposed within the can; and a header coupled to the can and comprising at least two 'header securing elements, for securing the header to tissue.
9. The apparatus according to claim 8, wherein the can comprises at least one can securing element.
10. Implantable apparatus, comprising: a biocompatible can; circuitry, disposed within the can; and two headers, disposed at opposite ends of the can.
11. The apparatus according to claim 10, wherein at least one of the headers comprises at least two header securing elements, for securing the at least one header to tissue.
12. The apparatus according to claim 10, wherein the can comprises at least one can securing element coupled to the can, for securing the can to tissue.
13. A method comprising: providing a device that includes a can and a header coupled to the can; and placing the device in a patient in an orientation in which the can is closer than the header to a head of the patient .
14. The method according to claim 13, comprising securing the can to an implantation site of the patient using a securing element of the can.
15. A method comprising: providing a device that includes a can and a header coupled to the can; placing the device in a patient; and securing, to tissue of the patient, at least one can securing element coupled to the can.
16. A method comprising: providing a device that includes a can and a header coupled to the can; placing the device in a patient; and securing, to tissue of the patient, at least two header securing elements coupled to the header.
17. A method comprising: providing a device that includes a can and two headers disposed at opposite ends of the can; and placing the device in a patient.
PCT/IL2006/000616 2005-05-26 2006-05-25 Suture loops for implantable device WO2006126201A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68523405P 2005-05-26 2005-05-26
US60/685,234 2005-05-26

Publications (2)

Publication Number Publication Date
WO2006126201A2 true WO2006126201A2 (en) 2006-11-30
WO2006126201A3 WO2006126201A3 (en) 2007-06-07

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8380312B2 (en) 2009-12-31 2013-02-19 Ams Research Corporation Multi-zone stimulation implant system and method
US9731112B2 (en) 2011-09-08 2017-08-15 Paul J. Gindele Implantable electrode assembly
US9889310B2 (en) 2014-07-23 2018-02-13 Medtronic, Inc. Suture loop with cover and strategic placement of suture points
WO2020068652A1 (en) * 2018-09-24 2020-04-02 Verily Life Sciences Llc Implantable pulse generator with suture holes, methods for implanting the same, and encapsulation of external components in active implantable medical devices
US11097115B2 (en) 2018-09-24 2021-08-24 Galvani Bioelectronics Limited Implantable pulse generator with suture holes and methods for implanting the same
WO2022053677A1 (en) * 2020-09-14 2022-03-17 Biotronik Se & Co. Kg Housing fixation
WO2022272001A3 (en) * 2021-06-23 2023-01-26 Children's Hospital Los Angeles Monolithic pericardial pacemakers

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US6907295B2 (en) 2001-08-31 2005-06-14 Biocontrol Medical Ltd. Electrode assembly for nerve control
US7904176B2 (en) 2006-09-07 2011-03-08 Bio Control Medical (B.C.M.) Ltd. Techniques for reducing pain associated with nerve stimulation
US8571653B2 (en) 2001-08-31 2013-10-29 Bio Control Medical (B.C.M.) Ltd. Nerve stimulation techniques
US8880192B2 (en) 2012-04-02 2014-11-04 Bio Control Medical (B.C.M.) Ltd. Electrode cuffs
US7627384B2 (en) 2004-11-15 2009-12-01 Bio Control Medical (B.C.M.) Ltd. Techniques for nerve stimulation

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US5411538A (en) * 1993-11-01 1995-05-02 Intermedics, Inc. Implantable medical device with detachable battery or electronic circuit
US5658321A (en) * 1995-06-09 1997-08-19 Ventritex, Inc. Conductive housing for implantable cardiac device
US6006135A (en) * 1997-09-26 1999-12-21 Medtronic, Inc. Apparatus for interconnecting implantable electrical leads and medical device
US6764472B1 (en) * 2000-01-11 2004-07-20 Bard Access Systems, Inc. Implantable refillable infusion device
US20060200200A1 (en) * 2005-03-04 2006-09-07 Malinowski Zdzislaw B Hermetic implantable stimulator

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Publication number Priority date Publication date Assignee Title
US5411538A (en) * 1993-11-01 1995-05-02 Intermedics, Inc. Implantable medical device with detachable battery or electronic circuit
US5658321A (en) * 1995-06-09 1997-08-19 Ventritex, Inc. Conductive housing for implantable cardiac device
US6006135A (en) * 1997-09-26 1999-12-21 Medtronic, Inc. Apparatus for interconnecting implantable electrical leads and medical device
US6764472B1 (en) * 2000-01-11 2004-07-20 Bard Access Systems, Inc. Implantable refillable infusion device
US20060200200A1 (en) * 2005-03-04 2006-09-07 Malinowski Zdzislaw B Hermetic implantable stimulator

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8380312B2 (en) 2009-12-31 2013-02-19 Ams Research Corporation Multi-zone stimulation implant system and method
US9731112B2 (en) 2011-09-08 2017-08-15 Paul J. Gindele Implantable electrode assembly
US9889310B2 (en) 2014-07-23 2018-02-13 Medtronic, Inc. Suture loop with cover and strategic placement of suture points
WO2020068652A1 (en) * 2018-09-24 2020-04-02 Verily Life Sciences Llc Implantable pulse generator with suture holes, methods for implanting the same, and encapsulation of external components in active implantable medical devices
US11097115B2 (en) 2018-09-24 2021-08-24 Galvani Bioelectronics Limited Implantable pulse generator with suture holes and methods for implanting the same
WO2022053677A1 (en) * 2020-09-14 2022-03-17 Biotronik Se & Co. Kg Housing fixation
WO2022272001A3 (en) * 2021-06-23 2023-01-26 Children's Hospital Los Angeles Monolithic pericardial pacemakers

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