WO2006108183A3 - Label free biosensors and cells - Google Patents

Label free biosensors and cells Download PDF

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Publication number
WO2006108183A3
WO2006108183A3 PCT/US2006/013539 US2006013539W WO2006108183A3 WO 2006108183 A3 WO2006108183 A3 WO 2006108183A3 US 2006013539 W US2006013539 W US 2006013539W WO 2006108183 A3 WO2006108183 A3 WO 2006108183A3
Authority
WO
WIPO (PCT)
Prior art keywords
cells
label free
free biosensors
biosensors
methods
Prior art date
Application number
PCT/US2006/013539
Other languages
French (fr)
Other versions
WO2006108183A2 (en
Inventor
Ye Fang
Ann M Ferrie
Norman H Fontaine
Joydeep Lahiri
Po Ki Yuen
Original Assignee
Corning Inc
Ye Fang
Ann M Ferrie
Norman H Fontaine
Joydeep Lahiri
Po Ki Yuen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corning Inc, Ye Fang, Ann M Ferrie, Norman H Fontaine, Joydeep Lahiri, Po Ki Yuen filed Critical Corning Inc
Priority to CN200680019857.1A priority Critical patent/CN101500481B/en
Priority to EP06749802.2A priority patent/EP1874950B1/en
Priority to US11/887,809 priority patent/US8076090B2/en
Priority to JP2008505660A priority patent/JP5129119B2/en
Publication of WO2006108183A2 publication Critical patent/WO2006108183A2/en
Publication of WO2006108183A3 publication Critical patent/WO2006108183A3/en
Priority to US13/281,996 priority patent/US8338116B2/en
Priority to US13/675,396 priority patent/US8852876B2/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Disclosed are compositions and methods for using label free optical biosensors for performing cell assays. In certain embodiments the assays can be performed in highthough put methods and can be multiplexed.
PCT/US2006/013539 2005-04-05 2006-04-05 Label free biosensors and cells WO2006108183A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CN200680019857.1A CN101500481B (en) 2005-04-05 2006-04-05 methods for detecting influence on cells by stimulating event
EP06749802.2A EP1874950B1 (en) 2005-04-05 2006-04-05 Label free biosensors
US11/887,809 US8076090B2 (en) 2005-04-05 2006-04-05 Label free biosensors and cells
JP2008505660A JP5129119B2 (en) 2005-04-05 2006-04-05 Label-free biosensors and cells
US13/281,996 US8338116B2 (en) 2005-04-05 2011-10-26 Label free biosensors and cells
US13/675,396 US8852876B2 (en) 2005-04-05 2012-11-13 Label free biosensors and cells

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66890805P 2005-04-05 2005-04-05
US60/668,908 2005-04-05

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US11/887,809 A-371-Of-International US8076090B2 (en) 2005-04-05 2006-04-05 Label free biosensors and cells
US13/281,996 Division US8338116B2 (en) 2005-04-05 2011-10-26 Label free biosensors and cells

Publications (2)

Publication Number Publication Date
WO2006108183A2 WO2006108183A2 (en) 2006-10-12
WO2006108183A3 true WO2006108183A3 (en) 2009-04-16

Family

ID=37074131

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/013539 WO2006108183A2 (en) 2005-04-05 2006-04-05 Label free biosensors and cells

Country Status (5)

Country Link
US (3) US8076090B2 (en)
EP (2) EP1874950B1 (en)
JP (1) JP5129119B2 (en)
CN (2) CN103983772A (en)
WO (1) WO2006108183A2 (en)

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