WO2006069349A3 - Cell-loaded prostheses for regenerative intraluminal applications - Google Patents

Cell-loaded prostheses for regenerative intraluminal applications Download PDF

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Publication number
WO2006069349A3
WO2006069349A3 PCT/US2005/046926 US2005046926W WO2006069349A3 WO 2006069349 A3 WO2006069349 A3 WO 2006069349A3 US 2005046926 W US2005046926 W US 2005046926W WO 2006069349 A3 WO2006069349 A3 WO 2006069349A3
Authority
WO
WIPO (PCT)
Prior art keywords
prostheses
cell
loaded
blood vessels
regenerative
Prior art date
Application number
PCT/US2005/046926
Other languages
French (fr)
Other versions
WO2006069349A9 (en
WO2006069349A2 (en
Inventor
Eric Daniels
Brian Strem
Susan Lynn Riley
Emedio Mike De
John K Fraser
Marc H Hedrick
Original Assignee
Cytori Therapeutics Inc
Eric Daniels
Brian Strem
Susan Lynn Riley
Emedio Mike De
John K Fraser
Marc H Hedrick
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytori Therapeutics Inc, Eric Daniels, Brian Strem, Susan Lynn Riley, Emedio Mike De, John K Fraser, Marc H Hedrick filed Critical Cytori Therapeutics Inc
Publication of WO2006069349A2 publication Critical patent/WO2006069349A2/en
Publication of WO2006069349A9 publication Critical patent/WO2006069349A9/en
Publication of WO2006069349A3 publication Critical patent/WO2006069349A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body

Abstract

Cell-loaded devices or prostheses having various applications such as insertion into body passages are disclosed. The prostheses include cell carrier portions which are compatible with living tissue and which are loaded with therapeutic cell populations, and the prostheses can be applied within or replace one or more of narrow segments, environments which may be difficult to access or luminal areas of the body such as parts of blood vessels. In the context of blood vessels, the cell-loaded devices or prostheses can line or otherwise treat with therapeutic cell populations inner walls of damaged blood vessels and surrounding parenchyma or other organs.
PCT/US2005/046926 2004-12-22 2005-12-22 Cell-loaded prostheses for regenerative intraluminal applications WO2006069349A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63901304P 2004-12-22 2004-12-22
US60/639,013 2004-12-22

Publications (3)

Publication Number Publication Date
WO2006069349A2 WO2006069349A2 (en) 2006-06-29
WO2006069349A9 WO2006069349A9 (en) 2006-09-08
WO2006069349A3 true WO2006069349A3 (en) 2007-08-09

Family

ID=36602362

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/046926 WO2006069349A2 (en) 2004-12-22 2005-12-22 Cell-loaded prostheses for regenerative intraluminal applications

Country Status (1)

Country Link
WO (1) WO2006069349A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9580678B2 (en) 2013-06-21 2017-02-28 The Regents Of The University Of California Microfluidic tumor tissue dissociation device
US10561830B2 (en) 2013-10-08 2020-02-18 The Johns Hopkins University Cell impregnated sleeve for paracrine and other factor production
US10722540B1 (en) 2016-02-01 2020-07-28 The Regents Of The University Of California Microfluidic device and method for shear stress-induced transformation of cells
CA3051051A1 (en) 2016-06-08 2017-12-14 The Regents Of The University Of California Method and device for processing tissues and cells

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010000802A1 (en) * 1998-04-30 2001-05-03 Medtronic, Inc. Implantable system with drug-eluting cells for on-demand local drug delivery
US6368356B1 (en) * 1996-07-11 2002-04-09 Scimed Life Systems, Inc. Medical devices comprising hydrogel polymers having improved mechanical properties
US20020103542A1 (en) * 2000-09-18 2002-08-01 Bilbo Patrick R. Methods for treating a patient using a bioengineered flat sheet graft prostheses
US20030014126A1 (en) * 2001-06-28 2003-01-16 Patel Umesh H. Graft prosthesis devices containing renal capsule collagen

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6368356B1 (en) * 1996-07-11 2002-04-09 Scimed Life Systems, Inc. Medical devices comprising hydrogel polymers having improved mechanical properties
US20010000802A1 (en) * 1998-04-30 2001-05-03 Medtronic, Inc. Implantable system with drug-eluting cells for on-demand local drug delivery
US20020103542A1 (en) * 2000-09-18 2002-08-01 Bilbo Patrick R. Methods for treating a patient using a bioengineered flat sheet graft prostheses
US20030014126A1 (en) * 2001-06-28 2003-01-16 Patel Umesh H. Graft prosthesis devices containing renal capsule collagen

Also Published As

Publication number Publication date
WO2006069349A9 (en) 2006-09-08
WO2006069349A2 (en) 2006-06-29

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