WO2006066465A1 - A fusion implant for lumbal intervertebral columns - Google Patents

A fusion implant for lumbal intervertebral columns Download PDF

Info

Publication number
WO2006066465A1
WO2006066465A1 PCT/CN2005/000002 CN2005000002W WO2006066465A1 WO 2006066465 A1 WO2006066465 A1 WO 2006066465A1 CN 2005000002 W CN2005000002 W CN 2005000002W WO 2006066465 A1 WO2006066465 A1 WO 2006066465A1
Authority
WO
WIPO (PCT)
Prior art keywords
groove
shape
sides
facet
convex
Prior art date
Application number
PCT/CN2005/000002
Other languages
French (fr)
Chinese (zh)
Inventor
Tianjing Zhu
Original Assignee
Yang, Shouheng
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yang, Shouheng filed Critical Yang, Shouheng
Publication of WO2006066465A1 publication Critical patent/WO2006066465A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/4455—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30772—Apertures or holes, e.g. of circular cross section
    • A61F2002/30784—Plurality of holes
    • A61F2002/30785—Plurality of holes parallel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/3082—Grooves
    • A61F2002/30827—Plurality of grooves
    • A61F2002/30828—Plurality of grooves parallel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30841—Sharp anchoring protrusions for impaction into the bone, e.g. sharp pins, spikes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00359—Bone or bony tissue

Definitions

  • the invention belongs to the technical field of medical bone tools.
  • the instability of the spine occurs after removal of the lumbar disc herniation, or the degenerative lumbar disc disease is unstable, or the ⁇ ", ⁇ " spine slippage, etc., often placed between the vertebral bodies made of metal material
  • the internal fixation bracket - Cage for treatment For example, TFC and BAK, which were popular several years ago, have small bearing surfaces, which cause complications such as sinking and slippage after filling the bone, and are inconvenient to install.
  • the contact Fusion Cage (such as TELAMON, OIC- Titaniunu OIC- Peek) has been popular. ) replaced.
  • the technical solution of the present invention is a lumbar interbody fusion cage, see Fig. 1-2, having a body 4, which is made of fresh and healthy mammalian bones, and is made of fresh and healthy mammalian bones.
  • the body 4 has a vertebral shape, and the convex surfaces 1 are respectively disposed on the two sides of the main body 4.
  • the two sides of the main body 4 have two or more through holes 3, and the two sides of the main body 4 have a strip-shaped recess 2 at one end of the upper bottom surface. .
  • the lumbar interbody fusion cage of the present invention is taken from a fresh and healthy mammal
  • the bone is machined into a vertebral shape as described above, see Figure 1.
  • the section is in the shape of a 'work' shape, see Figure 2.
  • the front end of the body of the cage is smooth and streamlined, so that the implant resistance can be reduced to avoid nerve damage.
  • the convex surfaces on the two sides of the body are respectively distributed with the convex teeth 1 and can be engaged with the upper and lower end plates.
  • the finished lumbar interbody fusion cage can be used after sterilization.
  • the lumbar interbody fusion cage has greater mechanical strength and can be used for support fixation and fusion between the posterior lumbar vertebrae.
  • the bone connector made of bone material has non-toxic, non-carcinogenic and non-allergic reactions, has good compatibility with human tissues, can slowly absorb and fuse, and is convenient to install with special tools, so it can be considered as an ideal.
  • the finished product of the present invention is put into medical use, the following manner can be followed.
  • the cartilage surface of the vertebral body is cleaned, and the cage 2 is clamped by a special cage clamping clamp, and the cage is transversely fed into the intervertebral space. Note that the position is appropriate, and then rotate 90" to make the fusion force
  • the beam supports and closely contacts the endplate of the vertebral body, and exits the clamping jaw.
  • the structure of the cage with the convex teeth of the cone makes the friction increase and close tightly, so it does not withdraw with the holder.
  • the function of the through hole on the cage It is convenient for the autologous bone to grow in the future to facilitate bone fusion.
  • a lumbar interbody fixation fracturing machine comprising both the same and xenogeneic bones should fall within the scope of the present invention.
  • the invention adopts bone tissue as a material, has no immunogenicity, has high compressive strength, has high mechanical properties and image compatibility, and is suitable for support fixation and fusion between the posterior lumbar vertebrae.
  • the invention is convenient to take materials, safe and reliable in quality, and easy to install and apply.
  • the replacement of metallic materials with biological materials is in line with the physiological needs of human body.

Abstract

A fusion implant for lumbal inter-vertebral columns has a body (4) which is made from fresh and healthy mammiferous bones. The body has a shape of frustum. On the two conical side of the body are arranged projecting teeth (1). On the two planar sides of the body are made two or more through holes (3). There is a lengthwise groove (2) on the end of each planar side of the body towards the upper underside.

Description

腰椎椎体间固定融合器  Lumbar interbody fusion cage
技术领域 Technical field
本发明属于医疗用接骨器具技术领域。  The invention belongs to the technical field of medical bone tools.
背景技术 Background technique
骨科医疗实践中， 遇到摘除腰椎间盘突出后出现的脊柱不稳定， 或退行性腰椎间盘病变脊柱不稳定， 或 ΐ"、π"脊柱滑脱等情况， 常在 椎体间放置用金属材料制成的内固定支架 -Cage进行治疗处理。 如几 年前流行的 TFC、 BAK, 因承载面小， 填充接骨后会引起下沉与滑脱 等并发症， 且安装不便， 己被最近流行的 Contact Fusion Cage (如 TELAMON, OIC- Titaniunu OIC- Peek) 所代替。 然而， 不论是前者还 是后者， 所有这些内固定物几乎均是金属框架结构的异物， 而高分子 聚合物的 0IC-PEEK降解较快， 且框架内均要填充植骨， 故被认为不 够理想。  In orthopedic medical practice, the instability of the spine occurs after removal of the lumbar disc herniation, or the degenerative lumbar disc disease is unstable, or the ΐ", π" spine slippage, etc., often placed between the vertebral bodies made of metal material The internal fixation bracket - Cage for treatment. For example, TFC and BAK, which were popular several years ago, have small bearing surfaces, which cause complications such as sinking and slippage after filling the bone, and are inconvenient to install. Recently, the contact Fusion Cage (such as TELAMON, OIC- Titaniunu OIC- Peek) has been popular. ) replaced. However, both the former and the latter, all of these internal fixations are almost foreign bodies of metal frame structure, and the polymer of the polymer has a faster degradation of 0IC-PEEK, and the frame is filled with bone graft, so it is considered to be not ideal. .
发明内容 Summary of the invention
本发明的目的， 就是要提供一种既可作为椎体间的支撑固定物， 又可作为椎体间的植骨填充物的固定融合器。  It is an object of the present invention to provide a fixation cage that acts both as a support fixture between the vertebral bodies and as a bone graft between the vertebral bodies.
本发明的技术解决方案是， 一种腰椎椎体间固定融合器， 参见图 1-2, 具有本体 4， 所述本体 4取材新鲜健康的哺乳动物骨骼制作， 取 材新鲜健康的哺乳动物骨骼制作的该本体 4呈椎台形，本体 4两侧椎 面分别分布有凸齿 1， 本体 4两侧平面开有二个以上通孔 3， 本体 4 两侧平面朝向上底面一端开有条形凹槽 2。  The technical solution of the present invention is a lumbar interbody fusion cage, see Fig. 1-2, having a body 4, which is made of fresh and healthy mammalian bones, and is made of fresh and healthy mammalian bones. The body 4 has a vertebral shape, and the convex surfaces 1 are respectively disposed on the two sides of the main body 4. The two sides of the main body 4 have two or more through holes 3, and the two sides of the main body 4 have a strip-shaped recess 2 at one end of the upper bottom surface. .
本发明的这种腰椎椎体间固定融合器取材新鲜健康的哺乳动物 骨骼机械加工成如上述其本体呈椎台形， 见图 1。 截面呈 '工' 字形 之弹头状， 见图 2。 该融合器本体前端圆滑呈流线形， 故可减小植入 阻力避免神经损伤。 而本体两侧椎面又分别分布有凸齿 1， 可与上下 终板相啮合。成品腰椎椎体间固定融合器可以经灭菌处理后备用。本 腰椎椎体间固定融合器有较大的机械强度，可用于腰椎后路椎体间的 支撑固定和融合。用骨骼材料制成的本接骨器具有无毒、无致癌性与 无过敏反应， 与人体组织相容性好， 可缓慢吸收融合， 且用专用工具 安装较为方便， 故可认为是一种理想的 L1〜S 1 后路椎体间固定融合 器。 The lumbar interbody fusion cage of the present invention is taken from a fresh and healthy mammal The bone is machined into a vertebral shape as described above, see Figure 1. The section is in the shape of a 'work' shape, see Figure 2. The front end of the body of the cage is smooth and streamlined, so that the implant resistance can be reduced to avoid nerve damage. The convex surfaces on the two sides of the body are respectively distributed with the convex teeth 1 and can be engaged with the upper and lower end plates. The finished lumbar interbody fusion cage can be used after sterilization. The lumbar interbody fusion cage has greater mechanical strength and can be used for support fixation and fusion between the posterior lumbar vertebrae. The bone connector made of bone material has non-toxic, non-carcinogenic and non-allergic reactions, has good compatibility with human tissues, can slowly absorb and fuse, and is convenient to install with special tools, so it can be considered as an ideal. L1~S 1 posterior interbody fusion cage.
本发明的成品投入医疗使用时， 可遵循下述方式。将椎间盘摘除 后， 清净椎体软骨面， 用专用融合器夹持钳夹持融合器凹槽 2， 将融 合器横行送入椎间隙，·注意位置适当， 然后旋转 90"， 让融合器工字 梁支撑和紧密接触椎体终板， 退出夹持钳， 融合器呈椎形带凸齿的结 构使之磨擦加大结合紧密， 故不会随着夹持器退出。融合器上通孔的 作用是为自体骨日后长入提供方便， 以利于骨融合。  When the finished product of the present invention is put into medical use, the following manner can be followed. After the disc is removed, the cartilage surface of the vertebral body is cleaned, and the cage 2 is clamped by a special cage clamping clamp, and the cage is transversely fed into the intervertebral space. Note that the position is appropriate, and then rotate 90" to make the fusion force The beam supports and closely contacts the endplate of the vertebral body, and exits the clamping jaw. The structure of the cage with the convex teeth of the cone makes the friction increase and close tightly, so it does not withdraw with the holder. The function of the through hole on the cage It is convenient for the autologous bone to grow in the future to facilitate bone fusion.
应该指出的是，包括同种和异种骨骼加工成的腰椎椎体间固定融 合器都应落在本发明的保护范围之内。  It should be noted that a lumbar interbody fixation fracturing machine comprising both the same and xenogeneic bones should fall within the scope of the present invention.
本发明采用骨骼组织作材料， 无免疫抗原性， 其抗压强度大， 具 有极高的机械性能和影像兼容性，适合于腰椎后路椎体间的支撑固定 和融合需要。  The invention adopts bone tissue as a material, has no immunogenicity, has high compressive strength, has high mechanical properties and image compatibility, and is suitable for support fixation and fusion between the posterior lumbar vertebrae.
本发明取材方便， 质量安全可靠， 易于安装应用。 以生物材料取 代金属材料， 符合人体生理需要。  The invention is convenient to take materials, safe and reliable in quality, and easy to install and apply. The replacement of metallic materials with biological materials is in line with the physiological needs of human body.

Claims

附图说明 图 1为本发明腰椎椎体间固定融合器的结构示意图。 图 2是图 1中 A- A向剖视图。 以上图 1-2中， 1一凸齿 2—凹槽 3—通孔 4一本体 具体实施方式 实施例 1 :本例采用牛骨骨骼组织作材料，经刨、铣制成高 25mm， 下底面长 14扁， 上底面长 10誦， 厚 10mm规格的椎台形本体 4， 凹槽 槽径 Φ 6ΜΙΙ。 凹槽处截面呈工字形。 将两侧椎面分别铣制加工成带凸 齿 1的椎面，凸齿 1排列均匀，再在本体 4之平面上开设二个通孔 3， 孑 L径 Φ 5ιηιη。 实施例 2:本例采用猪骨骨骼组织作材料，经刨、铣制成高 20隱， 下底面长 9腦， 上底面长 7瞧， 厚 7mm规格的椎台形本体 4， 凹槽槽 径 Φ ½ηι。 凹槽处截面呈工字形。 将两侧椎面分别铣制加工成带凸齿 1的椎面， 凸齿 1排列均匀， 再在本体 4之平面上开设二个通孔 3， 孔径 Φ 3ΙΉΠΙ。 由此构成的本发明的腰椎椎体间固定融合器经试制试用被证明 整体效果良好， 质量可靠， 安全实用， 疗效显著。 权利 要 求 BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a schematic structural view of a lumbar interbody fusion cage according to the present invention. Figure 2 is a cross-sectional view taken along line A-A of Figure 1; In the above figure 1-2, a convex tooth 2 - a groove 3 - a through hole 4 - a body embodiment 1 : This example uses bovine bone skeleton tissue as a material, plane and milling to make a height of 25 mm, the bottom surface The length is 14 flat, the upper base is 10 inches long, and the platform body 4 is 10 mm thick. The groove diameter is Φ 6ΜΙΙ. The cross section at the groove is in the shape of an I-shape. The two sides of the facet are respectively milled into a facet with a convex tooth 1, and the convex teeth 1 are evenly arranged, and then two through holes 3 are formed in the plane of the body 4, and the diameter L is Φ 5ιηιη. Example 2: This example uses porcine bone and bone tissue as the material, which is made by planing and milling to make a height of 20 hidden, the lower bottom surface is 9 brains, the upper bottom surface is 7 inches long, and the thickness of the 7 mm-sized vertebra-shaped body 4 is the groove groove diameter Φ. 1⁄2ηι. The cross section at the groove is in the shape of an I-shape. The two sides of the facet are respectively milled into a facet with a convex tooth 1, and the convex teeth 1 are evenly arranged, and then two through holes 3 are formed in the plane of the body 4, and the aperture Φ 3 ΙΉΠΙ. The thus constructed lumbar interbody fusion cage of the present invention has been proved to have a good overall effect, reliable quality, safety and practicability, and remarkable curative effect. Rights request
1、 一种腰椎椎体间固定融合器， 具有本体 （4)， 其特征在于， 所述本体 （4) 取材新鲜健康的哺乳动物骨骼制作， 取材新鲜健康的 哺乳动物骨骼制作的该本体（4)呈椎台形， 本体（4)两侧椎面分别 分布有凸齿 （1)， 本体 （4) 两侧平面开有二个以上通孔 （3)， 本体 (4) 两侧平面朝向上底面一端开有条形凹槽 （2)。  A lumbar interbody fusion cage having a body (4), wherein the body (4) is made of fresh and healthy mammalian bones, and the body is made of fresh and healthy mammalian bones (4) In the shape of a vertebral table, the convex surfaces (1) are respectively distributed on the two sides of the body (4), and two or more through holes (3) are formed on the two sides of the body (4), and the planes on both sides of the body (4) face the upper bottom surface A strip groove (2) is opened at one end.
PCT/CN2005/000002 2004-12-23 2005-01-04 A fusion implant for lumbal intervertebral columns WO2006066465A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN200410047086.X 2004-12-23
CN 200410047086 CN1795832A (en) 2004-12-23 2004-12-23 Fixing fusion device for vertebral bodies of lumbar

Publications (1)

Publication Number Publication Date
WO2006066465A1 true WO2006066465A1 (en) 2006-06-29

Family

ID=36601358

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2005/000002 WO2006066465A1 (en) 2004-12-23 2005-01-04 A fusion implant for lumbal intervertebral columns

Country Status (2)

Country Link
CN (1) CN1795832A (en)
WO (1) WO2006066465A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102335050B (en) * 2011-07-22 2014-07-16 李健 Tool for producing bone graft capable of being directly implanted into intervertenral space
CN103494657A (en) * 2013-08-15 2014-01-08 刘官喜生 Fusion cage

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192327A (en) * 1991-03-22 1993-03-09 Brantigan John W Surgical prosthetic implant for vertebrae
CN2163617Y (en) * 1993-06-04 1994-05-04 何时军 Internal fixator for fracture of thoracic and lumbar vertebra
CN2320212Y (en) * 1997-10-21 1999-05-26 谭明生 Internal fixation device for automatic opening reduction of spine
WO2001032110A2 (en) * 1999-11-03 2001-05-10 Tutogen Medical Gmbh Implant consisting of bone material
US6719798B2 (en) * 1999-08-20 2004-04-13 Peter Metz-Stavenhagen Vertebral column segment

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192327A (en) * 1991-03-22 1993-03-09 Brantigan John W Surgical prosthetic implant for vertebrae
CN2163617Y (en) * 1993-06-04 1994-05-04 何时军 Internal fixator for fracture of thoracic and lumbar vertebra
CN2320212Y (en) * 1997-10-21 1999-05-26 谭明生 Internal fixation device for automatic opening reduction of spine
US6719798B2 (en) * 1999-08-20 2004-04-13 Peter Metz-Stavenhagen Vertebral column segment
WO2001032110A2 (en) * 1999-11-03 2001-05-10 Tutogen Medical Gmbh Implant consisting of bone material

Also Published As

Publication number Publication date
CN1795832A (en) 2006-07-05

Similar Documents

Publication Publication Date Title
JP3636719B2 (en) Prosthetic implant for fusion of intervertebral spine
US9439779B2 (en) Composite implant
KR0153410B1 (en) Spinal implant and method of fusing together adjacent vertebrae of its use
US20120065734A1 (en) Intervertebral plate system
CN110063820B (en) 3D printing interbody fusion cage with interfacial bone ingrowth activity and preparation method thereof
JP2008528125A (en) Articulating intervertebral disc implant with amorphous metal elements
TW200422032A (en) Intervertebral implant comprising joint parts that are mounted to form a universal joint
KR20100081303A (en) Spinal interbody replacement devices
JP2005515024A (en) Spinal defect correction device
JP2007503924A (en) Multiple allograft implants
WO2013060168A1 (en) Fusion prosthesis
TWM333885U (en) Vertebral plate-like fixation for improving bone fusion efficiency
CN108514465B (en) Intervertebral fusion device filled with artificial bone
KR20170053890A (en) Cage device
WO2006066465A1 (en) A fusion implant for lumbal intervertebral columns
CN113749830A (en) 3D prints porous type interbody fusion cage
CN111658242A (en) Intervertebral fusion cage
CN216985303U (en) Porous tantalum lumbar vertebra fusion cage
CA3234038A1 (en) Bone repair device and surgical kit
RU2465870C1 (en) Intervertebral disc prosthesis
CN210582758U (en) 3D prints interbody fusion cage with interface bone grows into active
CN107252372B (en) Mortise and tenon type cervical vertebra intervertebral fixer
WO2006066466A1 (en) A filling member for fixing and fusing together adjacent cervical vertebrae
CN219720967U (en) Fusion device
US20240033101A1 (en) Flexible intervertebral fusion cage with opening

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

DPE2 Request for preliminary examination filed before expiration of 19th month from priority date (pct application filed from 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 05700377

Country of ref document: EP

Kind code of ref document: A1

WWW Wipo information: withdrawn in national office

Ref document number: 5700377

Country of ref document: EP