WO2006054280A3 - System and method for delivering fluid into flexible biological barrier - Google Patents

System and method for delivering fluid into flexible biological barrier Download PDF

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Publication number
WO2006054280A3
WO2006054280A3 PCT/IL2005/000522 IL2005000522W WO2006054280A3 WO 2006054280 A3 WO2006054280 A3 WO 2006054280A3 IL 2005000522 W IL2005000522 W IL 2005000522W WO 2006054280 A3 WO2006054280 A3 WO 2006054280A3
Authority
WO
WIPO (PCT)
Prior art keywords
barrier
biological barrier
biological
delivering fluid
flexible
Prior art date
Application number
PCT/IL2005/000522
Other languages
French (fr)
Other versions
WO2006054280A2 (en
Inventor
Yehushua Yeshurun
Meir Hefetz
Yoel Sefi
Yotam Levin
Gilad Lavi
Original Assignee
Nanopass Technologies Ltd
Yehushua Yeshurun
Meir Hefetz
Yoel Sefi
Yotam Levin
Gilad Lavi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/IL2004/001065 external-priority patent/WO2005049107A2/en
Application filed by Nanopass Technologies Ltd, Yehushua Yeshurun, Meir Hefetz, Yoel Sefi, Yotam Levin, Gilad Lavi filed Critical Nanopass Technologies Ltd
Priority to US11/719,541 priority Critical patent/US8007466B2/en
Priority to EP05741986.3A priority patent/EP1819379B1/en
Priority to CA2587216A priority patent/CA2587216C/en
Priority to JP2007542497A priority patent/JP5026980B2/en
Publication of WO2006054280A2 publication Critical patent/WO2006054280A2/en
Publication of WO2006054280A3 publication Critical patent/WO2006054280A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
    • A61M2005/341—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub angularly adjustable or angled away from the axis of the injector
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen

Abstract

A system and method for delivering fluid into a flexible biological barrier employs a microneedle (12) structure wherein a final position of microneedles inserted into the biological barrier (14) is generally sideways projecting from the delivery configuration instead of the conventional downwards projecting arrangement. The microneedles project from a relief surface (16) which is distinct from a primary biological-barrier contact region (18, 26) of the delivery configuration, and is typically angled upwards away from the biological barrier. During insertion, the contact region is brought into contact with the biological barrier and moved parallel to the surface of the flexible biological barrier so as to generate a boundary (20) between a stretched portion (22) and a non-stretched portion (24) of the barrier.
PCT/IL2005/000522 2004-11-18 2005-05-19 System and method for delivering fluid into flexible biological barrier WO2006054280A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US11/719,541 US8007466B2 (en) 2004-11-18 2005-05-19 System and method for delivering fluid into flexible biological barrier
EP05741986.3A EP1819379B1 (en) 2004-11-18 2005-05-19 System for delivering fluid into flexible biological barrier
CA2587216A CA2587216C (en) 2004-11-18 2005-05-19 System and method for delivering fluid into flexible biological barrier
JP2007542497A JP5026980B2 (en) 2004-11-18 2005-05-19 Device for supplying fluid into a flexible biological barrier

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ILPCT/IL2004/001065 2004-11-18
PCT/IL2004/001065 WO2005049107A2 (en) 2003-11-18 2004-11-18 Enhanced penetration system and method for sliding microneedles
US65186105P 2005-02-11 2005-02-11
US60/651,861 2005-02-11

Publications (2)

Publication Number Publication Date
WO2006054280A2 WO2006054280A2 (en) 2006-05-26
WO2006054280A3 true WO2006054280A3 (en) 2006-10-12

Family

ID=36407535

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2005/000522 WO2006054280A2 (en) 2004-11-18 2005-05-19 System and method for delivering fluid into flexible biological barrier

Country Status (4)

Country Link
US (1) US8007466B2 (en)
EP (1) EP1819379B1 (en)
CA (1) CA2587216C (en)
WO (1) WO2006054280A2 (en)

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US8696637B2 (en) 2011-02-28 2014-04-15 Kimberly-Clark Worldwide Transdermal patch containing microneedles
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US20170246439A9 (en) 2011-10-27 2017-08-31 Kimberly-Clark Worldwide, Inc. Increased Bioavailability of Transdermally Delivered Agents
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WO2016209959A2 (en) 2015-06-22 2016-12-29 Alk-Abelló A/S Peptide combinations and use thereof in treating cedar pollen allergy
WO2017004561A1 (en) 2015-07-01 2017-01-05 Alk-Abelló A/S Peptide combinations and uses thereof for treating grass allergy
WO2017179025A1 (en) 2016-04-15 2017-10-19 Alk-Abelló A/S Epitope polypeptides of ragweed pollen allergens
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Also Published As

Publication number Publication date
EP1819379A4 (en) 2010-10-06
EP1819379A2 (en) 2007-08-22
US20090069788A1 (en) 2009-03-12
CA2587216C (en) 2014-11-18
US8007466B2 (en) 2011-08-30
WO2006054280A2 (en) 2006-05-26
CA2587216A1 (en) 2006-05-26
EP1819379B1 (en) 2016-08-31

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